Motif ID: DBP.p2

Z-value: 1.534


Transcription factors associated with DBP.p2:

Gene SymbolEntrez IDGene Name
DBP 1628 D site of albumin promoter (albumin D-box) binding protein

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
DBPchr19_-_491405690.029.3e-01Click!


Activity profile for motif DBP.p2.

activity profile for motif DBP.p2


Sorted Z-values histogram for motif DBP.p2

Sorted Z-values for motif DBP.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of DBP.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_228678556 6.119 NM_001130046
NM_004591
CCL20

chemokine (C-C motif) ligand 20

chr4_-_186732208 5.351 NM_001145671
SORBS2
sorbin and SH3 domain containing 2
chr4_-_186732047 5.077 NM_001145672
SORBS2
sorbin and SH3 domain containing 2
chr4_-_155533882 5.047 NM_000509
NM_021870
FGG

fibrinogen gamma chain

chr10_+_7745341 4.919 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chrX_-_105282714 4.527 NM_000354
SERPINA7
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr10_+_7745284 4.465 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr2_-_88427535 4.231 NM_001443
FABP1
fatty acid binding protein 1, liver
chr3_+_186330711 3.989 AHSG
alpha-2-HS-glycoprotein
chr3_+_186330844 3.950 NM_001622
AHSG
alpha-2-HS-glycoprotein
chr2_-_21266809 3.937 APOB
apolipoprotein B (including Ag(x) antigen)
chr3_+_186330859 3.750 AHSG
alpha-2-HS-glycoprotein
chr2_-_21266915 3.718 NM_000384
APOB
apolipoprotein B (including Ag(x) antigen)
chr3_-_149095333 3.584 TM4SF1
transmembrane 4 L six family member 1
chr2_-_21266893 3.480 APOB
apolipoprotein B (including Ag(x) antigen)
chrX_+_115567746 3.307 NM_007231
SLC6A14
solute carrier family 6 (amino acid transporter), member 14
chr12_+_56473944 3.015 ERBB3
v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
chr12_+_100867550 3.007 NM_001206977
NM_001206978
NM_001206979
NM_005123
NR1H4



nuclear receptor subfamily 1, group H, member 4



chr4_-_155511838 2.997 NM_000508
NM_021871
FGA

fibrinogen alpha chain

chr4_-_155533850 2.957 FGG
fibrinogen gamma chain
chr4_-_23891608 2.899 NM_013261
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr10_+_7745325 2.895 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr3_-_187452669 2.855 NM_001134738
BCL6
B-cell CLL/lymphoma 6
chr12_+_100867739 2.842 NR1H4
nuclear receptor subfamily 1, group H, member 4
chr15_-_90349819 2.588 ANPEP
alanyl (membrane) aminopeptidase
chr3_-_145879222 2.525 NM_000935
NM_182943
PLOD2

procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2

chr1_-_173176314 2.428 NM_003326
TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr4_+_88896838 2.377 SPP1
secreted phosphoprotein 1
chr14_-_94854910 2.344 SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr9_-_75567915 2.344 ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr14_-_94855120 2.326 NM_000295
SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr3_-_145878936 2.321 PLOD2
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr11_-_115088628 2.312 CADM1
cell adhesion molecule 1
chr17_-_7082654 2.249 NM_001197216
NM_001671
ASGR1

asialoglycoprotein receptor 1

chr4_+_88896868 2.225 SPP1
secreted phosphoprotein 1
chr3_-_145878775 2.203 PLOD2
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr9_-_75568232 2.155 NM_000689
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr3_-_114343791 2.139 NM_001164346
ZBTB20
zinc finger and BTB domain containing 20
chr5_+_71502700 1.992 MAP1B
microtubule-associated protein 1B
chr3_-_148939784 1.872 NM_000096
CP
ceruloplasmin (ferroxidase)
chr13_-_48987247 1.863 LPAR6
lysophosphatidic acid receptor 6
chr12_-_9268513 1.850 A2M
alpha-2-macroglobulin
chr3_-_149095413 1.824 TM4SF1
transmembrane 4 L six family member 1
chr16_+_69680959 1.801 NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr22_+_38201113 1.755 NM_005318
H1F0
H1 histone family, member 0
chr20_+_11898536 1.730 NM_014962
BTBD3
BTB (POZ) domain containing 3
chr3_-_149095458 1.722 TM4SF1
transmembrane 4 L six family member 1
chr4_+_71062241 1.721 NM_017855
ODAM
odontogenic, ameloblast asssociated
chr3_-_149095517 1.700 NM_014220
TM4SF1
transmembrane 4 L six family member 1
chr2_+_128176019 1.685 PROC
protein C (inactivator of coagulation factors Va and VIIIa)
chr2_+_128175989 1.675 NM_000312
PROC
protein C (inactivator of coagulation factors Va and VIIIa)
chr12_-_9268522 1.673 NM_000014
A2M
alpha-2-macroglobulin
chr2_+_62934030 1.658 NM_001142614
EHBP1
EH domain binding protein 1
chr17_-_39093671 1.643 NM_015515
KRT23
keratin 23 (histone deacetylase inducible)
chr3_-_52479042 1.630 NM_020163
SEMA3G
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
chr13_-_48987017 1.625 LPAR6
lysophosphatidic acid receptor 6
chr17_-_26697310 1.579 VTN
vitronectin
chr12_-_9268440 1.578 A2M
alpha-2-macroglobulin
chr17_-_26697224 1.552 VTN
vitronectin
chr14_-_65409445 1.551 NM_002083
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr13_-_46679143 1.543 NM_001872
NM_016413
CPB2

carboxypeptidase B2 (plasma)

chr13_-_48987652 1.534 NM_001162498
LPAR6
lysophosphatidic acid receptor 6
chr4_-_89978117 1.507 NM_014883
FAM13A
family with sequence similarity 13, member A
chr2_-_216259197 1.479 FN1
fibronectin 1
chr10_+_7745229 1.469 NM_002216
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr22_+_38201232 1.459 H1F0
H1 histone family, member 0
chr22_+_21128378 1.442 NM_000185
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr13_+_97874540 1.435 NM_144778
NM_207304
MBNL2

muscleblind-like 2 (Drosophila)

chr10_+_7745354 1.374 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr12_-_9268475 1.367 A2M
alpha-2-macroglobulin
chr17_-_26697358 1.359 NM_000638
VTN
vitronectin
chr5_-_42811959 1.330 NM_001085486
NM_001093726
NM_005410
SEPP1


selenoprotein P, plasma, 1


chr7_+_100770378 1.327 NM_000602
NM_001165413
SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

chr3_-_149375584 1.319 NM_001168280
NM_015472
WWTR1

WW domain containing transcription regulator 1

chr17_+_27369917 1.317 NM_016518
PIPOX
pipecolic acid oxidase
chr20_-_22564893 1.314 FOXA2
forkhead box A2
chr7_+_94297448 1.309 PEG10
paternally expressed 10
chr9_+_103791030 1.305 NM_207299
LPPR1
lipid phosphate phosphatase-related protein type 1
chr3_-_12941547 1.304 IQSEC1
IQ motif and Sec7 domain 1
chr4_-_100140330 1.294 NM_000672
NM_001102470
ADH6

alcohol dehydrogenase 6 (class V)

chr17_-_8424217 1.287 MYH10
myosin, heavy chain 10, non-muscle
chr10_+_5136556 1.286 NM_003739
AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr4_-_155533800 1.276 FGG
fibrinogen gamma chain
chr13_-_75901897 1.275 TBC1D4
TBC1 domain family, member 4
chr6_-_29527701 1.232 NM_006398
UBD
ubiquitin D
chr13_-_49018802 1.231 NM_005767
LPAR6
lysophosphatidic acid receptor 6
chr10_+_5136613 1.208 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr12_-_89745997 1.195 DUSP6
dual specificity phosphatase 6
chr14_-_24777153 1.181 CIDEB
cell death-inducing DFFA-like effector b
chr1_+_220863627 1.171 NM_024709
C1orf115
chromosome 1 open reading frame 115
chr6_-_11382501 1.154 NM_001142393
NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr3_-_49726081 1.137 NM_020998
MST1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr17_-_39092714 1.126 KRT23
keratin 23 (histone deacetylase inducible)
chr1_+_44064509 1.126 PTPRF
protein tyrosine phosphatase, receptor type, F
chr3_-_114478117 1.124 NM_001164344
NM_001164345
ZBTB20

zinc finger and BTB domain containing 20

chr10_+_5136589 1.124 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr14_-_24777184 1.105 CIDEB
cell death-inducing DFFA-like effector b
chr3_-_114343052 1.105 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chr5_-_172755418 1.095 STC2
stanniocalcin 2
chr17_-_34308455 1.077 NM_004590
CCL16
chemokine (C-C motif) ligand 16
chr16_-_73092533 1.046 NM_001164766
ZFHX3
zinc finger homeobox 3
chr3_+_124303505 1.028 NM_007064
KALRN
kalirin, RhoGEF kinase
chr6_+_31982538 1.028 NM_001242823
NM_001252204
NM_007293
NM_001002029
LOC100293534
C4A

C4B
complement C4-B-like
complement component 4A (Rodgers blood group)

complement component 4B (Chido blood group)
chr15_-_90347534 1.023 ANPEP
alanyl (membrane) aminopeptidase
chr6_-_29527477 1.004 UBD
ubiquitin D
chr15_+_59904090 0.994 GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr11_+_19372270 0.993 NM_001111018
NAV2
neuron navigator 2
chr17_+_72429835 0.982 NM_018653
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr17_-_56492938 0.978 RNF43
ring finger protein 43
chrX_+_23801431 0.975 SAT1
spermidine/spermine N1-acetyltransferase 1
chr4_-_159094163 0.975 NM_001031700
NM_001128424
FAM198B

family with sequence similarity 198, member B

chr11_-_128894008 0.969 NM_014715
ARHGAP32
Rho GTPase activating protein 32
chr14_-_24777160 0.964 CIDEB
cell death-inducing DFFA-like effector b
chr20_-_45976626 0.959 ZMYND8
zinc finger, MYND-type containing 8
chr5_-_111091947 0.939 NM_001142483
C5orf13
chromosome 5 open reading frame 13
chr1_+_229440128 0.930 NM_006542
SPHAR
S-phase response (cyclin related)
chr1_+_207277577 0.924 NM_000715
C4BPA
complement component 4 binding protein, alpha
chr6_+_31949800 0.924 NM_001242823
NM_001252204
NM_007293
NM_001002029
LOC100293534
C4A

C4B
complement C4-B-like
complement component 4A (Rodgers blood group)

complement component 4B (Chido blood group)
chr5_-_95158365 0.922 GLRX
glutaredoxin (thioltransferase)
chr6_-_47253962 0.917 TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr2_-_152830448 0.911 NM_001005747
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr20_-_34543280 0.896 NM_016558
SCAND1
SCAN domain containing 1
chr3_-_170744767 0.895 NM_000340
SLC2A2
solute carrier family 2 (facilitated glucose transporter), member 2
chr6_+_151561094 0.890 NM_005100
AKAP12
A kinase (PRKA) anchor protein 12
chr12_-_89746238 0.880 DUSP6
dual specificity phosphatase 6
chrX_-_131573638 0.878 NM_018388
NM_133486
MBNL3

muscleblind-like 3 (Drosophila)

chr14_-_36278335 0.874 NM_014990
NM_194301
RALGAPA1

Ral GTPase activating protein, alpha subunit 1 (catalytic)

chr6_+_163984574 0.863 QKI
QKI, KH domain containing, RNA binding
chr1_-_173886464 0.863 NM_000488
SERPINC1
serpin peptidase inhibitor, clade C (antithrombin), member 1
chr6_-_47254143 0.857 TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr8_-_29120571 0.850 NM_015254
KIF13B
kinesin family member 13B
chr1_+_28764660 0.834 NM_023923
PHACTR4
phosphatase and actin regulator 4
chr5_+_176516550 0.833 NM_022963
FGFR4
fibroblast growth factor receptor 4
chr3_-_48671278 0.824 NM_001040454
SLC26A6
solute carrier family 26, member 6
chr1_+_167298382 0.822 POU2F1
POU class 2 homeobox 1
chr3_-_49459870 0.812 AMT
aminomethyltransferase
chr5_-_95158465 0.805 NM_001118890
NM_001243658
NM_001243659
NM_002064
GLRX



glutaredoxin (thioltransferase)



chr4_-_16077740 0.803 NM_001145849
NM_001145850
NM_001145851
NM_001145852
NM_006017
PROM1




prominin 1




chr11_+_129991582 0.802 APLP2
amyloid beta (A4) precursor-like protein 2
chrX_-_130423199 0.791 IGSF1
immunoglobulin superfamily, member 1
chr4_-_139163222 0.786 NM_014331
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr17_-_56494889 0.786 RNF43
ring finger protein 43
chr7_-_87342569 0.779 NM_000927
ABCB1
ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr17_+_72427535 0.778 NM_022036
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr3_+_171757413 0.775 NM_022763
FNDC3B
fibronectin type III domain containing 3B
chr15_+_59903980 0.772 NM_004751
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr6_+_151561508 0.764 AKAP12
A kinase (PRKA) anchor protein 12
chr20_-_22565050 0.755 NM_021784
FOXA2
forkhead box A2
chr16_-_28621279 0.752 NM_001055
NM_177529
SULT1A1

sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1

chr18_+_32621299 0.745 NM_014268
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr2_-_166930130 0.742 NM_001165963
NM_001165964
NM_006920
SCN1A


sodium channel, voltage-gated, type I, alpha subunit


chr7_-_121784236 0.742 NM_005763
AASS
aminoadipate-semialdehyde synthase
chr3_-_139258477 0.737 RBP1
retinol binding protein 1, cellular
chr20_-_34241830 0.730 NM_003915
CPNE1
copine I
chr8_-_17579729 0.728 NM_001001931
MTUS1
microtubule associated tumor suppressor 1
chr1_+_57320442 0.726 NM_000562
C8A
complement component 8, alpha polypeptide
chr1_+_212788359 0.721 NM_001206486
ATF3
activating transcription factor 3
chr2_+_211458078 0.721 NM_001122634
CPS1
carbamoyl-phosphate synthase 1, mitochondrial
chr10_-_74283693 0.714 NM_001195519
MICU1
mitochondrial calcium uptake 1
chr4_-_111563278 0.714 NM_001204397
NM_001204398
NM_001204399
NM_153426
NM_153427
PITX2




paired-like homeodomain 2




chr17_-_56494930 0.708 NM_017763
RNF43
ring finger protein 43
chr3_-_32022734 0.708 OSBPL10
oxysterol binding protein-like 10
chr13_-_49001042 0.704 NM_001162497
LPAR6
lysophosphatidic acid receptor 6
chr8_+_26435920 0.702 NM_001244604
DPYSL2
dihydropyrimidinase-like 2
chr1_-_23886284 0.701 NM_002167
ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr16_+_15031299 0.701 NM_006985
NPIP
nuclear pore complex interacting protein
chr7_+_134576150 0.701 NM_033139
NM_033140
CALD1

caldesmon 1

chr9_-_84304378 0.696 TLE1
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr17_+_28705981 0.691 CPD
carboxypeptidase D
chr5_+_140588267 0.685 NM_018932
PCDHB12
protocadherin beta 12
chr3_-_187463474 0.673 NM_001706
BCL6
B-cell CLL/lymphoma 6
chr2_+_138721807 0.666 NM_001024074
NM_001024075
NM_006895
HNMT


histamine N-methyltransferase


chr2_+_102508377 0.664 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr3_+_35721115 0.664 NM_001025068
NM_001025069
ARPP21

cAMP-regulated phosphoprotein, 21kDa

chr1_+_82266081 0.659 NM_012302
LPHN2
latrophilin 2
chr8_-_17580024 0.655 NM_001166393
MTUS1
microtubule associated tumor suppressor 1
chr2_-_167005641 0.651 NM_001202435
SCN1A
sodium channel, voltage-gated, type I, alpha subunit
chr1_-_23885916 0.644 ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr14_-_24777064 0.641


chr7_+_134576187 0.640 CALD1
caldesmon 1
chr14_-_54421269 0.637 NM_130851
BMP4
bone morphogenetic protein 4
chr3_-_139258531 0.635 NM_001130992
NM_001130993
NM_002899
RBP1


retinol binding protein 1, cellular


chr2_+_102508333 0.631 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr1_-_173886401 0.630 SERPINC1
serpin peptidase inhibitor, clade C (antithrombin), member 1
chrY_+_16635625 0.618 NM_014893
NLGN4Y
neuroligin 4, Y-linked
chr8_-_17555158 0.614 NM_020749
MTUS1
microtubule associated tumor suppressor 1
chr11_+_22696318 0.608 NM_005256
GAS2
growth arrest-specific 2
chr2_-_174830429 0.605 NM_001172712
NM_003111
SP3

Sp3 transcription factor

chr1_+_226016428 0.601 EPHX1
epoxide hydrolase 1, microsomal (xenobiotic)
chr6_-_131291480 0.599 NM_001199389
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr10_+_57358749 0.598 NM_001190478
MTRNR2L5
MT-RNR2-like 5
chr10_-_65028825 0.595 NM_004241
JMJD1C
jumonji domain containing 1C
chr18_+_3453771 0.591 NM_173211
TGIF1
TGFB-induced factor homeobox 1
chr22_-_31742329 0.587 PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr21_-_43786602 0.585 NM_003225
TFF1
trefoil factor 1
chr9_-_123812535 0.571 NM_001735
C5
complement component 5
chr3_-_187463227 0.569 BCL6
B-cell CLL/lymphoma 6
chr17_+_48624519 0.567 NM_022827
SPATA20
spermatogenesis associated 20
chr18_+_72922725 0.563 NM_005786
TSHZ1
teashirt zinc finger homeobox 1
chr7_+_134464417 0.562 CALD1
caldesmon 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
4.50 2.30e-05 GO:0009611 response to wounding
1.86 1.04e-04 GO:0050896 response to stimulus
2.73 1.60e-04 GO:0042221 response to chemical stimulus
20.24 2.48e-04 GO:0010951 negative regulation of endopeptidase activity
2.61 4.08e-04 GO:0006950 response to stress
2.94 4.82e-04 GO:0048583 regulation of response to stimulus
8.11 7.86e-04 GO:0032101 regulation of response to external stimulus
24.85 8.47e-04 GO:0030193 regulation of blood coagulation
23.04 1.25e-03 GO:0050818 regulation of coagulation
15.32 1.31e-03 GO:0002576 platelet degranulation
20.10 2.50e-03 GO:0061041 regulation of wound healing
13.34 2.97e-03 GO:0010466 negative regulation of peptidase activity
70.81 4.27e-03 GO:0034694 response to prostaglandin stimulus
4.52 5.76e-03 GO:0042060 wound healing
4.68 1.02e-02 GO:0080134 regulation of response to stress
8.12 1.26e-02 GO:0006887 exocytosis
21.59 1.81e-02 GO:0006953 acute-phase response
9.70 1.86e-02 GO:0051346 negative regulation of hydrolase activity
6.18 2.28e-02 GO:0006954 inflammatory response
4.47 3.78e-02 GO:0007596 blood coagulation
4.47 3.78e-02 GO:0050817 coagulation
4.44 4.01e-02 GO:0007599 hemostasis
4.02 4.08e-02 GO:0009725 response to hormone stimulus
125.87 4.56e-02 GO:0071379 cellular response to prostaglandin stimulus

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
5.69 9.15e-09 GO:0005615 extracellular space
29.06 2.32e-08 GO:0031983 vesicle lumen
4.75 7.78e-08 GO:0044421 extracellular region part
3.46 3.88e-07 GO:0005576 extracellular region
24.11 1.49e-05 GO:0031093 platelet alpha granule lumen
23.61 1.70e-05 GO:0034774 secretory granule lumen
22.67 2.18e-05 GO:0060205 cytoplasmic membrane-bounded vesicle lumen
20.24 4.34e-05 GO:0031091 platelet alpha granule
80.92 4.69e-04 GO:0005577 fibrinogen complex
6.31 3.49e-02 GO:0030141 stored secretory granule

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
15.05 7.74e-07 GO:0004866 endopeptidase inhibitor activity
14.79 9.04e-07 GO:0030414 peptidase inhibitor activity
14.41 1.14e-06 GO:0061135 endopeptidase regulator activity
11.90 6.11e-06 GO:0061134 peptidase regulator activity
18.28 9.33e-05 GO:0004867 serine-type endopeptidase inhibitor activity
7.67 2.53e-04 GO:0004857 enzyme inhibitor activity
3.88 5.00e-04 GO:0030234 enzyme regulator activity
2.92 4.46e-02 GO:0005102 receptor binding