Motif ID: EGR1..3.p2

Z-value: 1.195


Transcription factors associated with EGR1..3.p2:

Gene SymbolEntrez IDGene Name
EGR1 1958 early growth response 1
EGR2 1959 early growth response 2 (Krox-20 homolog, Drosophila)
EGR3 1960 early growth response 3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
EGR2chr10_-_645760740.449.0e-02Click!
EGR1chr5_+_1378011660.371.6e-01Click!
EGR3chr8_-_22550057,
chr8_-_22550708,
chr8_-_22549901
-0.048.8e-01Click!


Activity profile for motif EGR1..3.p2.

activity profile for motif EGR1..3.p2


Sorted Z-values histogram for motif EGR1..3.p2

Sorted Z-values for motif EGR1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EGR1..3.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_133119624 1.270 NM_001164617
NM_001164618
NM_001164619
NM_004484
GPC3



glypican 3



chrX_-_133119475 1.207 GPC3
glypican 3
chr20_-_61569227 1.206 DIDO1
death inducer-obliterator 1
chr20_-_61569265 1.130 NM_022105
NM_033081
NM_080797
DIDO1


death inducer-obliterator 1


chr1_-_32801606 1.054 NM_023009
MARCKSL1
MARCKS-like 1
chr17_-_79008372 0.949 FLJ90757
uncharacterized LOC440465
chr14_+_101193313 0.926 DLK1
delta-like 1 homolog (Drosophila)
chr19_-_18717577 0.926 CRLF1
cytokine receptor-like factor 1
chr9_+_128509616 0.882 NM_006195
PBX3
pre-B-cell leukemia homeobox 3
chr20_+_61569358 0.882 NM_017896
C20orf11
chromosome 20 open reading frame 11
chr20_-_50384861 0.869 ATP9A
ATPase, class II, type 9A
chr6_-_74363689 0.844 NM_012434
SLC17A5
solute carrier family 17 (anion/sugar transporter), member 5
chr16_+_69600110 0.842 NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr7_-_51384458 0.810 NM_015198
COBL
cordon-bleu homolog (mouse)
chr10_-_75255718 0.791 PPP3CB
protein phosphatase 3, catalytic subunit, beta isozyme
chr9_+_35829208 0.776 NM_016446
NM_001042589
TMEM8B

transmembrane protein 8B

chr19_+_16435734 0.775 KLF2
Kruppel-like factor 2 (lung)
chr19_+_16435632 0.763 NM_016270
KLF2
Kruppel-like factor 2 (lung)
chr2_+_54683276 0.763 NM_003128
SPTBN1
spectrin, beta, non-erythrocytic 1
chr12_-_106641675 0.754 NM_006825
CKAP4
cytoskeleton-associated protein 4
chr15_-_61521416 0.745 RORA
RAR-related orphan receptor A
chr5_-_172755418 0.722 STC2
stanniocalcin 2
chr17_-_15466772 0.716 NM_001204478
NM_001135036
NM_145301
FAM18B2-CDRT4
FAM18B2

FAM18B2-CDRT4 readthrough
family with sequence similarity 18, member B2

chr4_-_74124305 0.709


chr10_+_89623419 0.696 PTEN
phosphatase and tensin homolog
chr1_+_60280462 0.688 NM_015888
HOOK1
hook homolog 1 (Drosophila)
chr19_-_18717631 0.680 NM_004750
CRLF1
cytokine receptor-like factor 1
chr20_-_50384899 0.679 NM_006045
ATP9A
ATPase, class II, type 9A
chr16_-_73092533 0.667 NM_001164766
ZFHX3
zinc finger homeobox 3
chr16_-_402617 0.662 NM_003502
NM_181050
AXIN1

axin 1

chr20_+_34894190 0.661 DLGAP4
discs, large (Drosophila) homolog-associated protein 4
chr19_-_18717467 0.658 CRLF1
cytokine receptor-like factor 1
chr20_+_45338125 0.652 NM_030777
SLC2A10
solute carrier family 2 (facilitated glucose transporter), member 10
chr11_-_2160199 0.651 NM_000612
IGF2
insulin-like growth factor 2 (somatomedin A)
chr17_-_76921076 0.638 TIMP2
TIMP metallopeptidase inhibitor 2
chr2_+_234263141 0.634 NM_152879
DGKD
diacylglycerol kinase, delta 130kDa
chr19_-_18392436 0.633 JUND
jun D proto-oncogene
chr6_+_89791510 0.627 PNRC1
proline-rich nuclear receptor coactivator 1
chr20_+_34742656 0.621 NM_012156
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr2_-_99347430 0.619 MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr2_+_234263153 0.615 DGKD
diacylglycerol kinase, delta 130kDa
chr13_+_20532788 0.611 NM_003453
NM_197968
NM_001190964
ZMYM2


zinc finger, MYM-type 2


chr19_+_45349560 0.610 PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr6_-_111136330 0.598 CDK19
cyclin-dependent kinase 19
chr17_+_65822206 0.598 BPTF
bromodomain PHD finger transcription factor
chr6_-_11044354 0.595 NM_017770
ELOVL2
ELOVL fatty acid elongase 2
chr6_+_37137882 0.594 NM_001243186
NM_002648
PIM1

pim-1 oncogene

chr6_-_46459010 0.590 NM_001251974
RCAN2
regulator of calcineurin 2
chr19_+_4969126 0.587 KDM4B
lysine (K)-specific demethylase 4B
chr1_-_200638996 0.583 DDX59
DEAD (Asp-Glu-Ala-Asp) box polypeptide 59
chrX_+_9432980 0.581 NM_005647
TBL1X
transducin (beta)-like 1X-linked
chrX_-_108976453 0.575 ACSL4
acyl-CoA synthetase long-chain family member 4
chr19_-_2702738 0.575 NM_052847
GNG7
guanine nucleotide binding protein (G protein), gamma 7
chr17_-_66287256 0.574 NM_001174166
NM_004694
SLC16A6

solute carrier family 16, member 6 (monocarboxylic acid transporter 7)

chr17_+_65822242 0.567 BPTF
bromodomain PHD finger transcription factor
chr1_+_150122246 0.566 PLEKHO1
pleckstrin homology domain containing, family O member 1
chr15_-_60884615 0.564 NM_134262
RORA
RAR-related orphan receptor A
chr8_+_38644754 0.563 TACC1
transforming, acidic coiled-coil containing protein 1
chr3_+_12329332 0.559 NM_005037
NM_138712
PPARG

peroxisome proliferator-activated receptor gamma

chr16_+_69599869 0.557 NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr19_+_708766 0.549 NM_001040134
NM_002579
PALM

paralemmin

chr15_-_61521478 0.548 NM_134261
RORA
RAR-related orphan receptor A
chrX_-_154688260 0.546 NM_001007523
NM_001007524
NM_012151
F8A2
F8A3
F8A1
coagulation factor VIII-associated 2
coagulation factor VIII-associated 3
coagulation factor VIII-associated 1
chr10_+_131265500 0.544 MGMT
O-6-methylguanine-DNA methyltransferase
chr1_+_150122415 0.543 PLEKHO1
pleckstrin homology domain containing, family O member 1
chrX_+_154114609 0.540 NM_001007523
NM_001007524
NM_012151
F8A2
F8A3
F8A1
coagulation factor VIII-associated 2
coagulation factor VIII-associated 3
coagulation factor VIII-associated 1
chr11_+_46403205 0.538 NM_002391
MDK
midkine (neurite growth-promoting factor 2)
chr1_-_85930733 0.537 NM_012137
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr2_+_97481977 0.537 NM_017623
NM_199078
CNNM3

cyclin M3

chr19_-_41196419 0.536 NM_004756
NUMBL
numb homolog (Drosophila)-like
chr18_-_25757351 0.536 NM_001792
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr6_+_107811272 0.535 NM_018013
SOBP
sine oculis binding protein homolog (Drosophila)
chr19_+_4969123 0.530 NM_015015
KDM4B
lysine (K)-specific demethylase 4B
chr7_+_65338161 0.528 NM_173517
VKORC1L1
vitamin K epoxide reductase complex, subunit 1-like 1
chrX_-_71792610 0.520 HDAC8
histone deacetylase 8
chr17_+_72428228 0.515 GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr19_+_2476122 0.512 NM_015675
GADD45B
growth arrest and DNA-damage-inducible, beta
chrX_+_47092362 0.512 USP11
ubiquitin specific peptidase 11
chrX_-_1571733 0.503 NM_001173474
NM_004192
ASMTL

acetylserotonin O-methyltransferase-like

chr10_+_131265453 0.502 NM_002412
MGMT
O-6-methylguanine-DNA methyltransferase
chr10_+_89623367 0.501 PTEN
phosphatase and tensin homolog
chr8_-_57123827 0.495 PLAG1
pleiomorphic adenoma gene 1
chr11_+_68079999 0.495 NM_002335
LRP5
low density lipoprotein receptor-related protein 5
chrY_-_1521733 0.494 NM_001173474
NM_004192
ASMTL

acetylserotonin O-methyltransferase-like

chr9_+_137218324 0.493 RXRA
retinoid X receptor, alpha
chr14_+_101193190 0.493 NM_003836
DLK1
delta-like 1 homolog (Drosophila)
chr14_-_38064440 0.492 NM_004496
FOXA1
forkhead box A1
chr16_+_23568833 0.484 NM_019116
UBFD1
ubiquitin family domain containing 1
chr17_-_56065474 0.484 VEZF1
vascular endothelial zinc finger 1
chrX_-_43741593 0.482 NM_000898
MAOB
monoamine oxidase B
chr14_+_101193275 0.482 DLK1
delta-like 1 homolog (Drosophila)
chr8_+_38644721 0.482 NM_001122824
NM_006283
TACC1

transforming, acidic coiled-coil containing protein 1

chr7_+_102715580 0.476 ARMC10
armadillo repeat containing 10
chr16_+_69599868 0.473 NM_001113178
NM_006599
NM_138713
NM_138714
NM_173214
NM_173215
NFAT5





nuclear factor of activated T-cells 5, tonicity-responsive





chr7_+_55955129 0.472 ZNF713
zinc finger protein 713
chr16_-_3930685 0.472 CREBBP
CREB binding protein
chr17_-_3599359 0.471 P2RX5
purinergic receptor P2X, ligand-gated ion channel, 5
chr9_+_131314669 0.470 NM_001130438
NM_001195532
NM_003127
SPTAN1


spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)


chr18_+_55102777 0.469 NM_004852
ONECUT2
one cut homeobox 2
chr1_+_65613211 0.463 NM_203464
NM_001005353
AK4

adenylate kinase 4

chr6_-_16761600 0.461 NM_000332
NM_001128164
ATXN1

ataxin 1

chr19_-_46000159 0.459 NM_005619
NM_206900
RTN2

reticulon 2

chr7_-_87104974 0.458 NM_000443
NM_018849
NM_018850
ABCB4


ATP-binding cassette, sub-family B (MDR/TAP), member 4


chr19_+_45349392 0.457 NM_001042724
NM_002856
PVRL2

poliovirus receptor-related 2 (herpesvirus entry mediator B)

chr1_+_17866276 0.456 NM_018125
ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr10_+_89623091 0.455 NM_000314
PTEN
phosphatase and tensin homolog
chr14_-_89883306 0.454 NM_005197
FOXN3
forkhead box N3
chr4_-_74124456 0.453 NM_032217
NM_198889
ANKRD17

ankyrin repeat domain 17

chr6_-_109777171 0.447 NM_001159291
NM_022765
MICAL1

microtubule associated monoxygenase, calponin and LIM domain containing 1

chr5_-_172755195 0.447 STC2
stanniocalcin 2
chr15_-_45480160 0.446 SHF
Src homology 2 domain containing F
chr17_-_74236272 0.445 NM_052916
RNF157
ring finger protein 157
chr22_-_38713217 0.443 CSNK1E
casein kinase 1, epsilon
chr2_+_27651483 0.441 NRBP1
nuclear receptor binding protein 1
chr14_-_53417636 0.434 FERMT2
fermitin family member 2
chr19_-_33793429 0.429 NM_004364
CEBPA
CCAAT/enhancer binding protein (C/EBP), alpha
chr6_-_167369990 0.427 RNASET2
ribonuclease T2
chr19_-_39340609 0.425 NM_001533
HNRNPL
heterogeneous nuclear ribonucleoprotein L
chr12_+_7023490 0.424 NM_001975
ENO2
enolase 2 (gamma, neuronal)
chr13_+_20532881 0.424 ZMYM2
zinc finger, MYM-type 2
chr20_-_22564893 0.422 FOXA2
forkhead box A2
chr6_-_109777085 0.421 MICAL1
microtubule associated monoxygenase, calponin and LIM domain containing 1
chr2_+_204192915 0.421 NM_005759
ABI2
abl-interactor 2
chr1_+_169075869 0.420 NM_001677
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr1_-_151431648 0.419 POGZ
pogo transposable element with ZNF domain
chr4_+_37892698 0.419 NM_015173
TBC1D1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr16_+_2588000 0.418 PDPK1
3-phosphoinositide dependent protein kinase-1
chr16_+_23569045 0.417 UBFD1
ubiquitin family domain containing 1
chr16_+_2588021 0.416 PDPK1
3-phosphoinositide dependent protein kinase-1
chr9_+_35829375 0.416 NM_001042590
TMEM8B
transmembrane protein 8B
chr10_+_124768401 0.416 NM_001609
ACADSB
acyl-CoA dehydrogenase, short/branched chain
chrX_+_152907892 0.416 NM_001395
DUSP9
dual specificity phosphatase 9
chr20_+_61273823 0.415 SLCO4A1
solute carrier organic anion transporter family, member 4A1
chr9_-_15510899 0.411 NM_001128217
NM_033222
PSIP1

PC4 and SFRS1 interacting protein 1

chr19_-_18392413 0.411 NM_005354
JUND
jun D proto-oncogene
chr6_-_109776942 0.410 MICAL1
microtubule associated monoxygenase, calponin and LIM domain containing 1
chr22_-_38713384 0.410 NM_152221
CSNK1E
casein kinase 1, epsilon
chr14_-_53417808 0.409 NM_001134999
NM_001135000
NM_006832
FERMT2


fermitin family member 2


chr6_-_109776946 0.408 MICAL1
microtubule associated monoxygenase, calponin and LIM domain containing 1
chr6_-_111804413 0.408 NM_002912
REV3L
REV3-like, catalytic subunit of DNA polymerase zeta (yeast)
chr11_-_75236866 0.407 GDPD5
glycerophosphodiester phosphodiesterase domain containing 5
chr1_-_146643722 0.406 PRKAB2
protein kinase, AMP-activated, beta 2 non-catalytic subunit
chr20_+_61448391 0.405 NM_001853
COL9A3
collagen, type IX, alpha 3
chr19_-_2702662 0.404 GNG7
guanine nucleotide binding protein (G protein), gamma 7
chr6_-_131384387 0.404 NM_001135554
NM_001135555
NM_001199388
NM_001431
EPB41L2



erythrocyte membrane protein band 4.1-like 2



chrX_-_128657453 0.402 NM_003069
NM_139035
SMARCA1

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1

chr7_+_75544472 0.401 POR
P450 (cytochrome) oxidoreductase
chr19_+_1071208 0.400 HMHA1
histocompatibility (minor) HA-1
chr2_+_235860616 0.398 NM_014521
SH3BP4
SH3-domain binding protein 4
chr16_+_23569027 0.397 UBFD1
ubiquitin family domain containing 1
chrX_-_128657440 0.396 SMARCA1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr2_-_99347588 0.396 NM_012214
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr6_-_167370037 0.394 NM_003730
RNASET2
ribonuclease T2
chr16_+_85646923 0.394 NM_014615
KIAA0182
KIAA0182
chr22_+_42229137 0.394 SREBF2
sterol regulatory element binding transcription factor 2
chr12_+_70759974 0.393 NM_014505
KCNMB4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr6_-_111136407 0.392 NM_015076
CDK19
cyclin-dependent kinase 19
chrX_+_154611748 0.391 NM_001007523
NM_001007524
NM_012151
F8A2
F8A3
F8A1
coagulation factor VIII-associated 2
coagulation factor VIII-associated 3
coagulation factor VIII-associated 1
chr2_-_220408264 0.388 NM_024536
CHPF
chondroitin polymerizing factor
chr2_+_86668270 0.388 NM_018433
KDM3A
lysine (K)-specific demethylase 3A
chr2_-_97535669 0.386 NM_017789
SEMA4C
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr5_-_137088952 0.386 HNRNPA0
heterogeneous nuclear ribonucleoprotein A0
chr1_+_182992329 0.385 NM_002293
LAMC1
laminin, gamma 1 (formerly LAMB2)
chr3_+_171757413 0.383 NM_022763
FNDC3B
fibronectin type III domain containing 3B
chr6_-_143266283 0.382 NM_006734
HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
chr4_-_105412466 0.381 NM_025212
CXXC4
CXXC finger protein 4
chr1_+_182992694 0.381


chr19_-_15442685 0.380 BRD4
bromodomain containing 4
chr8_-_57123858 0.378 NM_001114634
NM_001114635
NM_002655
PLAG1


pleiomorphic adenoma gene 1


chr10_+_45869667 0.376 ALOX5
arachidonate 5-lipoxygenase
chrX_-_128657381 0.375 SMARCA1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr4_+_6271605 0.371 WFS1
Wolfram syndrome 1 (wolframin)
chr3_+_53195214 0.370 NM_006254
NM_212539
PRKCD

protein kinase C, delta

chr19_-_39340548 0.369 HNRNPL
heterogeneous nuclear ribonucleoprotein L
chr19_+_45349584 0.368 PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr16_+_2587989 0.366 PDPK1
3-phosphoinositide dependent protein kinase-1
chr2_-_225907312 0.365 NM_014689
DOCK10
dedicator of cytokinesis 10
chr17_-_81009642 0.365 NM_001009905
B3GNTL1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
chr1_+_151584665 0.362 SNX27
sorting nexin family member 27
chr9_-_116163530 0.362 ALAD
aminolevulinate dehydratase
chr3_+_73046081 0.360 NM_174907
PPP4R2
protein phosphatase 4, regulatory subunit 2
chr7_-_103629962 0.360 NM_005045
NM_173054
RELN

reelin

chr11_-_86666211 0.358 NM_012193
FZD4
frizzled family receptor 4
chr2_-_64246205 0.357 NM_001005739
NM_016516
VPS54

vacuolar protein sorting 54 homolog (S. cerevisiae)

chr10_+_114709963 0.356 NM_001146274
NM_001146283
NM_001146284
NM_001146285
NM_001146286
NM_001198525
NM_001198526
NM_001198527
NM_001198528
NM_001198529
NM_001198530
NM_001198531
NM_030756
TCF7L2












transcription factor 7-like 2 (T-cell specific, HMG-box)












chr1_-_115053677 0.355 TRIM33
tripartite motif containing 33
chrX_+_47092264 0.353 NM_004651
USP11
ubiquitin specific peptidase 11
chr9_+_35605614 0.352 TESK1
testis-specific kinase 1
chr19_+_54057898 0.352 NM_001253801
ZNF331
zinc finger protein 331
chr9_-_130742803 0.352 NM_001035254
FAM102A
family with sequence similarity 102, member A
chr6_-_31239489 0.352 HLA-B
HLA-C
major histocompatibility complex, class I, B
major histocompatibility complex, class I, C
chr11_+_46403260 0.352 MDK
midkine (neurite growth-promoting factor 2)
chr10_-_125851850 0.351 NM_014863
NM_015892
CHST15

carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15

chr9_+_90112419 0.351 DAPK1
death-associated protein kinase 1
chr13_+_20532906 0.349 NM_001190965
ZMYM2
zinc finger, MYM-type 2
chr11_-_72852957 0.348 NM_014824
FCHSD2
FCH and double SH3 domains 2
chr7_+_73703704 0.347 NM_003388
NM_032421
CLIP2

CAP-GLY domain containing linker protein 2

chr2_+_30369868 0.346 YPEL5
yippee-like 5 (Drosophila)
chr1_-_235812994 0.346 NM_001098722
GNG4
guanine nucleotide binding protein (G protein), gamma 4
chr9_-_116163578 0.345 NM_000031
ALAD
aminolevulinate dehydratase

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.