Motif ID: EN1,2.p2

Z-value: 0.865


Transcription factors associated with EN1,2.p2:

Gene SymbolEntrez IDGene Name
EN1 2019 engrailed homeobox 1
EN2 2020 engrailed homeobox 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
EN1chr2_-_119605758-0.552.8e-02Click!
EN2chr7_+_155250705-0.543.1e-02Click!


Activity profile for motif EN1,2.p2.

activity profile for motif EN1,2.p2


Sorted Z-values histogram for motif EN1,2.p2

Sorted Z-values for motif EN1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EN1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_74281884 2.224 ALB
albumin
chr11_+_22696318 1.636 NM_005256
 GAS2
growth arrest-specific 2
chr10_-_98031154 1.444 NM_001114094
NM_013314
 BLNK

B-cell linker

chr12_+_53342842 1.433 NM_000224
 KRT18
keratin 18
chr17_-_39675078 1.407 NM_002275
 KRT15
keratin 15
chr12_+_53342899 1.184 KRT18
keratin 18
chr17_-_64225496 0.923 NM_000042
 APOH
apolipoprotein H (beta-2-glycoprotein I)
chr12_-_6486522 0.749 NM_001159575
 SCNN1A
sodium channel, nonvoltage-gated 1 alpha
chr6_+_30294224 0.739


chr11_+_60223281 0.736 NM_021950
NM_152866
 MS4A1

membrane-spanning 4-domains, subfamily A, member 1

chr12_-_53343607 0.733 KRT8
keratin 8
chr2_-_88427535 0.723 NM_001443
 FABP1
fatty acid binding protein 1, liver
chr14_-_65409445 0.694 NM_002083
 GPX2
glutathione peroxidase 2 (gastrointestinal)
chr6_+_32407618 0.693 NM_019111
 HLA-DRA
major histocompatibility complex, class II, DR alpha
chr10_+_114133838 0.685 NM_203379
 ACSL5
acyl-CoA synthetase long-chain family member 5
chr19_-_7764283 0.671 NM_001207019
 FCER2
Fc fragment of IgE, low affinity II, receptor for (CD23)
chr10_+_114133775 0.584 ACSL5
acyl-CoA synthetase long-chain family member 5
chr12_-_102591547 0.567 NM_002674
 PMCH
pro-melanin-concentrating hormone
chr3_-_148939784 0.562 NM_000096
 CP
ceruloplasmin (ferroxidase)
chr1_+_32043745 0.555 NM_001204415
 TINAGL1
tubulointerstitial nephritis antigen-like 1

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

Showing 1 to 3 of 3 entries
Enrichment   P-value GO Accession GO Term
52.87 7.53e-03 GO:0005882 intermediate filament
41.91 1.20e-02 GO:0045111 intermediate filament cytoskeleton
8.39 3.97e-02 GO:0044430 cytoskeletal part

Nothing significant found in function category.