Motif ID: ESR1.p2

Z-value: 1.724


Transcription factors associated with ESR1.p2:

Gene SymbolEntrez IDGene Name
ESR1 2099 estrogen receptor 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ESR1chr6_+_152011630-0.184.9e-01Click!


Activity profile for motif ESR1.p2.

activity profile for motif ESR1.p2


Sorted Z-values histogram for motif ESR1.p2

Sorted Z-values for motif ESR1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ESR1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_57976550 3.037 NM_001253835
NM_001553
 IGFBP7

insulin-like growth factor binding protein 7

chr11_+_129939792 2.617 APLP2
amyloid beta (A4) precursor-like protein 2
chr6_+_148663953 2.520 SASH1
SAM and SH3 domain containing 1
chr11_+_129939807 2.425 APLP2
amyloid beta (A4) precursor-like protein 2
chr11_+_129939787 2.419 APLP2
amyloid beta (A4) precursor-like protein 2
chr16_+_55515468 2.224 NM_001127891
 MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr6_+_148663728 2.206 NM_015278
 SASH1
SAM and SH3 domain containing 1
chr7_-_47621635 2.196 TNS3
tensin 3
chr11_+_129939667 2.184 NM_001142276
NM_001142277
NM_001142278
NM_001642
 APLP2



amyloid beta (A4) precursor-like protein 2



chr1_-_94702916 2.118 ARHGAP29
Rho GTPase activating protein 29
chr17_-_74707000 2.038 NM_001008528
NM_001008529
NM_198530
 MXRA7


matrix-remodelling associated 7


chr7_-_47621741 2.035 NM_022748
 TNS3
tensin 3
chr6_+_7541837 2.008 DSP
desmoplakin
chr6_+_7541892 1.981 DSP
desmoplakin
chr2_-_1748317 1.948 PXDN
peroxidasin homolog (Drosophila)
chr19_+_45349560 1.920 PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr6_+_7541863 1.880 NM_001008844
NM_004415
 DSP

desmoplakin

chr4_-_122618098 1.860 ANXA5
annexin A5
chr1_-_94703252 1.844 NM_004815
 ARHGAP29
Rho GTPase activating protein 29
chr12_-_124457099 1.840 NM_025140
 CCDC92
coiled-coil domain containing 92

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 2 of 2 entries
Enrichment   P-value GO Accession GO Term
21.05 1.46e-02 GO:0007266 Rho protein signal transduction
1.49 4.41e-02 GO:0065007 biological regulation

Gene overrepresentation in compartment category:

Showing 1 to 6 of 6 entries
Enrichment   P-value GO Accession GO Term
64.88 3.52e-02 GO:0005587 collagen type IV
55.61 4.92e-02 GO:0030935 sheet-forming collagen
5.93 1.64e-03 GO:0031012 extracellular matrix
3.50 1.37e-03 GO:0044421 extracellular region part
3.23 4.50e-02 GO:0005615 extracellular space
2.47 1.78e-02 GO:0005576 extracellular region

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
Enrichment   P-value GO Accession GO Term
20.86 3.29e-02 GO:0071814 protein-lipid complex binding
17.18 1.03e-04 GO:0005201 extracellular matrix structural constituent
1.51 6.07e-03 GO:0005515 protein binding