Motif ID: EVI1.p2

Z-value: 0.512


Transcription factors associated with EVI1.p2:

Gene SymbolEntrez IDGene Name
EVI1 2122 ecotropic viral integration site 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
MECOMchr3_-_169381417-0.292.7e-01Click!


Activity profile for motif EVI1.p2.

activity profile for motif EVI1.p2


Sorted Z-values histogram for motif EVI1.p2

Sorted Z-values for motif EVI1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EVI1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_+_64680858 0.640 NM_182913
SYNE2
spectrin repeat containing, nuclear envelope 2
chr5_+_102201526 0.620 NM_000919
NM_001177306
NM_138766
NM_138821
NM_138822
PAM




peptidylglycine alpha-amidating monooxygenase




chr22_+_23010757 0.609


chr2_-_89165652 0.545


chr3_-_145968819 0.514 PLSCR4
phospholipid scramblase 4
chr3_+_121774208 0.513 NM_001206924
NM_001206925
NM_175862
CD86


CD86 molecule


chr1_-_9117554 0.499 SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr6_+_32407618 0.498 NM_019111
HLA-DRA
major histocompatibility complex, class II, DR alpha
chr22_+_23213671 0.462 IGLV4-3
immunoglobulin lambda variable 4-3
chr11_+_5710926 0.457 TRIM22
tripartite motif containing 22
chr4_+_74281884 0.448 ALB
albumin
chr10_-_91102430 0.442 LIPA
lipase A, lysosomal acid, cholesterol esterase
chr1_-_98386525 0.435 DPYD
dihydropyrimidine dehydrogenase
chr12_-_15038724 0.432 NM_000900
NM_001190839
MGP

matrix Gla protein

chr3_-_145968958 0.428 NM_001128306
NM_001177304
NM_020353
PLSCR4


phospholipid scramblase 4


chr17_+_53344966 0.428 HLF
hepatic leukemia factor
chr18_-_53303129 0.427 NM_001243226
TCF4
transcription factor 4
chr1_-_98386594 0.406 NM_000110
NM_001160301
DPYD

dihydropyrimidine dehydrogenase

chr18_-_67624159 0.399 NM_006566
CD226
CD226 molecule
chr10_+_7745325 0.387 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr17_-_29648631 0.384 NM_001003927
NM_014210
EVI2A

ecotropic viral integration site 2A

chr22_+_23134980 0.383


chr14_+_75988838 0.373 BATF
basic leucine zipper transcription factor, ATF-like
chr7_-_150329285 0.369 GIMAP6
GTPase, IMAP family member 6
chr8_-_6420454 0.368 NM_001118887
NM_001118888
NM_001147
ANGPT2


angiopoietin 2


chr12_+_25205180 0.366 NM_001204126
NM_001204127
NM_006152
LRMP


lymphoid-restricted membrane protein


chr13_+_31309644 0.361 NM_001629
ALOX5AP
arachidonate 5-lipoxygenase-activating protein
chr7_-_150329735 0.356 NM_001244071
NM_001244072
NM_024711
GIMAP6


GTPase, IMAP family member 6


chr14_+_75988765 0.352 NM_006399
BATF
basic leucine zipper transcription factor, ATF-like
chr10_+_7745341 0.352 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr11_+_22696318 0.351 NM_005256
GAS2
growth arrest-specific 2
chr10_-_98031154 0.343 NM_001114094
NM_013314
BLNK

B-cell linker

chr2_-_175499275 0.340 NM_003387
WIPF1
WAS/WASL interacting protein family, member 1
chr13_-_110802708 0.334 COL4A1
collagen, type IV, alpha 1
chr14_-_23284565 0.334 SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr1_-_173174611 0.330 TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr12_+_21168629 0.324 NM_001009562
SLCO1B7
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr8_+_97505895 0.322 SDC2
syndecan 2
chr3_+_157154579 0.321 NM_002852
PTX3
pentraxin 3, long
chr10_+_31607419 0.320 ZEB1
zinc finger E-box binding homeobox 1
chr1_-_89591685 0.316 NM_004120
GBP2
guanylate binding protein 2, interferon-inducible
chr2_-_56151273 0.315 NM_001039348
NM_001039349
EFEMP1

EGF containing fibulin-like extracellular matrix protein 1

chr4_+_8951476 0.314 NM_001040071
LOC650293
seven transmembrane helix receptor
chr6_+_32605182 0.314 NM_002122
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr1_+_32739711 0.311 NM_001042771
LCK
lymphocyte-specific protein tyrosine kinase
chr7_+_94297448 0.310 PEG10
paternally expressed 10
chr7_-_30029904 0.305 NM_001145514
SCRN1
secernin 1
chr16_+_28943259 0.304 NM_001178098
NM_001770
CD19

CD19 molecule

chr19_-_36643770 0.303 NM_001864
COX7A1
cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
chr3_-_114790221 0.303 NM_001164343
ZBTB20
zinc finger and BTB domain containing 20
chr3_-_58200397 0.301 NM_004944
DNASE1L3
deoxyribonuclease I-like 3
chr4_+_74301932 0.300 NM_001134
AFP
alpha-fetoprotein
chr10_+_7745354 0.299 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr13_+_31309690 0.289 ALOX5AP
arachidonate 5-lipoxygenase-activating protein
chr9_+_79115548 0.283 NM_001097636
GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2
chr15_-_80263460 0.280 NM_001114735
NM_004049
BCL2A1

BCL2-related protein A1

chr8_+_97505876 0.277 NM_002998
SDC2
syndecan 2
chr2_+_33661392 0.263 NM_170672
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr3_-_105421044 0.259 CBLB
Cas-Br-M (murine) ecotropic retroviral transforming sequence b
chr11_+_114166534 0.256 NM_006169
NNMT
nicotinamide N-methyltransferase
chr12_-_9913415 0.254 NM_001781
CD69
CD69 molecule
chr3_+_148583042 0.254 NM_001870
CPA3
carboxypeptidase A3 (mast cell)
chr1_+_50569581 0.252 NM_001144776
ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr6_+_52529157 0.248 LOC730101
uncharacterized LOC730101
chr7_-_30029284 0.247 NM_001145515
NM_014766
NM_001145513
SCRN1


secernin 1


chr3_-_114478117 0.246 NM_001164344
NM_001164345
ZBTB20

zinc finger and BTB domain containing 20

chr5_+_92918924 0.245 NM_005654
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr8_-_80993009 0.245 NM_001025252
TPD52
tumor protein D52
chr10_-_45474210 0.243 NM_007021
C10orf10
chromosome 10 open reading frame 10
chr13_-_34250899 0.243 NM_001243476
STARD13
StAR-related lipid transfer (START) domain containing 13
chr15_-_60919642 0.243 NM_002943
NM_134260
RORA

RAR-related orphan receptor A

chr16_-_24968856 0.242 ARHGAP17
Rho GTPase activating protein 17
chr1_+_212738675 0.236 NM_001030287
ATF3
activating transcription factor 3
chr1_-_204459445 0.235 NM_002646
PIK3C2B
phosphoinositide-3-kinase, class 2, beta polypeptide
chr3_+_158991035 0.231 NM_001197107
NM_001197108
NM_014575
SCHIP1


schwannomin interacting protein 1


chr2_+_138721807 0.231 NM_001024074
NM_001024075
NM_006895
HNMT


histamine N-methyltransferase


chr8_-_17767871 0.230


chr19_+_50030874 0.228 NM_020650
RCN3
reticulocalbin 3, EF-hand calcium binding domain
chr16_+_53479685 0.227 RBL2
retinoblastoma-like 2 (p130)
chr7_-_24797557 0.216 NM_001127454
NM_004403
DFNA5

deafness, autosomal dominant 5

chr2_-_158300517 0.212 NM_004288
CYTIP
cytohesin 1 interacting protein
chr10_-_88717319 0.211 NM_024756
MMRN2
multimerin 2
chr21_-_39956823 0.209 NM_001243429
ERG
v-ets erythroblastosis virus E26 oncogene homolog (avian)
chr6_-_32784727 0.208 NM_002120
HLA-DOB
major histocompatibility complex, class II, DO beta
chr16_+_50731049 0.207 NM_022162
NOD2
nucleotide-binding oligomerization domain containing 2
chr10_+_7745284 0.207 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr19_+_55128601 0.207 NM_006669
LILRB1
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
chr2_+_102979096 0.206 NM_003855
IL18R1
interleukin 18 receptor 1
chr11_+_22689653 0.206 NM_177553
GAS2
growth arrest-specific 2
chr19_-_52490050 0.206 NM_021632
ZNF350
zinc finger protein 350
chr12_+_113344738 0.203 NM_001032409
NM_002534
NM_016816
OAS1


2'-5'-oligoadenylate synthetase 1, 40/46kDa


chr5_-_96149804 0.203 NM_001198541
ERAP1
endoplasmic reticulum aminopeptidase 1
chr1_-_161193190 0.203 APOA2
apolipoprotein A-II
chr1_-_103496768 0.201 COL11A1
collagen, type XI, alpha 1
chr19_+_50031232 0.199 RCN3
reticulocalbin 3, EF-hand calcium binding domain
chr14_+_95047758 0.199 SERPINA5
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr9_+_82186846 0.198 NM_007005
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr9_+_79968344 0.198 VPS13A
vacuolar protein sorting 13 homolog A (S. cerevisiae)
chr7_+_102553343 0.197 NM_001031692
NM_005824
LRRC17

leucine rich repeat containing 17

chr8_+_11351509 0.197 NM_001715
BLK
B lymphoid tyrosine kinase
chr1_-_146697155 0.194 NM_001144829
NM_001144830
NM_001461
FMO5


flavin containing monooxygenase 5


chr10_+_7745229 0.192 NM_002216
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr11_+_5710816 0.187 NM_001199573
NM_006074
TRIM22

tripartite motif containing 22

chr2_+_189839132 0.187 COL3A1
collagen, type III, alpha 1
chr14_-_106746056 0.184


chr14_+_95047792 0.183 SERPINA5
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr5_-_151066492 0.183 NM_003118
SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chr5_-_88179278 0.183 NM_001193350
NM_002397
MEF2C

myocyte enhancer factor 2C

chr18_+_72922725 0.181 NM_005786
TSHZ1
teashirt zinc finger homeobox 1
chr4_+_41614911 0.181 NM_001112719
NM_001112720
LIMCH1

LIM and calponin homology domains 1

chr6_+_26440699 0.180 NM_001242803
NM_006994
NM_197974
BTN3A3


butyrophilin, subfamily 3, member A3


chr6_-_75970566 0.179 TMEM30A
transmembrane protein 30A
chr20_+_36011936 0.178 SRC
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
chr11_+_114167197 0.173 NNMT
nicotinamide N-methyltransferase
chr13_+_98086315 0.173 NM_021033
RAP2A
RAP2A, member of RAS oncogene family
chr2_+_33738941 0.171 NM_015376
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr12_+_25205488 0.170 LRMP
lymphoid-restricted membrane protein
chr2_+_189839113 0.169 COL3A1
collagen, type III, alpha 1
chr21_+_43710190 0.169 ABCG1
ATP-binding cassette, sub-family G (WHITE), member 1
chr3_+_186330711 0.167 AHSG
alpha-2-HS-glycoprotein
chr14_-_94844881 0.167 SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr22_-_19512859 0.166 NM_001130861
NM_003277
CLDN5

claudin 5

chr4_-_159094163 0.165 NM_001031700
NM_001128424
FAM198B

family with sequence similarity 198, member B

chr4_+_155484131 0.163 NM_001184741
NM_005141
FGB

fibrinogen beta chain

chr1_+_111772332 0.163 NM_001025199
CHI3L2
chitinase 3-like 2
chr11_+_114167168 0.162 NNMT
nicotinamide N-methyltransferase
chr1_+_79115476 0.160 NM_006417
IFI44
interferon-induced protein 44
chr8_-_19460005 0.159 NM_001130518
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr17_-_62084282 0.158 NM_000873
ICAM2
intercellular adhesion molecule 2
chr4_+_68424444 0.156 NM_012108
STAP1
signal transducing adaptor family member 1
chr6_+_153019029 0.151 NM_025107
MYCT1
myc target 1
chr4_-_76944585 0.151 NM_001565
CXCL10
chemokine (C-X-C motif) ligand 10
chr7_-_87342569 0.151 NM_000927
ABCB1
ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr3_-_27498244 0.150 NM_003615
SLC4A7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr2_+_189839078 0.150 NM_000090
COL3A1
collagen, type III, alpha 1
chr6_-_32920812 0.148 NM_006120
HLA-DMA
major histocompatibility complex, class II, DM alpha
chr20_+_9198036 0.148 NM_182797
PLCB4
phospholipase C, beta 4
chr12_-_47219734 0.148 NM_001143824
NM_018018
SLC38A4

solute carrier family 38, member 4

chr12_+_75874512 0.148 NM_006851
GLIPR1
GLI pathogenesis-related 1
chr22_+_44395090 0.147 NM_001003828
PARVB
parvin, beta
chr8_+_74903563 0.147 NM_001195797
NM_015364
LY96

lymphocyte antigen 96

chr2_-_56150862 0.145 EFEMP1
EGF containing fibulin-like extracellular matrix protein 1
chr16_+_3115312 0.145 NM_001012631
NM_001012633
NM_001012718
NM_004221
IL32



interleukin 32



chr5_-_78282356 0.142 NM_000046
ARSB
arylsulfatase B
chr13_-_48987017 0.141 LPAR6
lysophosphatidic acid receptor 6
chr2_+_177053306 0.141 NM_024501
HOXD1
homeobox D1
chr7_-_115670828 0.141 NM_001018058
NM_012252
TFEC

transcription factor EC

chr12_-_10251520 0.139 NM_016511
CLEC1A
C-type lectin domain family 1, member A
chr5_+_156820161 0.138 CYFIP2
cytoplasmic FMR1 interacting protein 2
chr13_-_48987247 0.138 LPAR6
lysophosphatidic acid receptor 6
chr22_+_22723972 0.138


chr6_+_26383323 0.137 NM_001197238
NM_001197239
NM_001197240
NM_006995
NM_181531
NM_001197237
BTN2A2





butyrophilin, subfamily 2, member A2





chr2_-_188419185 0.136 NM_001032281
NM_006287
TFPI

tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)

chr20_-_23066828 0.136 NM_012072
CD93
CD93 molecule
chr1_+_210501595 0.134 NM_001122834
NM_001170564
HHAT

hedgehog acyltransferase

chr1_-_161193375 0.133 NM_001643
APOA2
apolipoprotein A-II
chr1_-_110933683 0.133 NM_001201546
NM_001201547
NM_001201548
NM_001201549
NM_004696
SLC16A4




solute carrier family 16, member 4 (monocarboxylic acid transporter 5)




chr7_+_17338182 0.132 NM_001621
AHR
aryl hydrocarbon receptor
chr17_-_34417386 0.132 NM_002983
CCL3
chemokine (C-C motif) ligand 3
chr19_-_8642232 0.132 MYO1F
myosin IF
chr2_-_24307529 0.131 NM_004881
NM_147184
TP53I3

tumor protein p53 inducible protein 3

chr13_-_48987652 0.128 NM_001162498
LPAR6
lysophosphatidic acid receptor 6
chr4_+_41614933 0.127 LIMCH1
LIM and calponin homology domains 1
chr4_-_70626429 0.125 NM_014465
SULT1B1
sulfotransferase family, cytosolic, 1B, member 1
chr16_+_12058963 0.125 NM_001192
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr20_-_20036685 0.124 NM_016652
CRNKL1
crooked neck pre-mRNA splicing factor-like 1 (Drosophila)
chr22_-_36562224 0.123 NM_145641
NM_145642
APOL3

apolipoprotein L, 3

chr10_+_11047274 0.122 CELF2
CUGBP, Elav-like family member 2
chr3_-_46249787 0.122 NM_001295
CCR1
chemokine (C-C motif) receptor 1
chr6_-_22297729 0.121 NM_000948
PRL
prolactin
chr6_-_24936177 0.121 FAM65B
family with sequence similarity 65, member B
chr1_+_162602198 0.120 NM_001014796
NM_006182
DDR2

discoidin domain receptor tyrosine kinase 2

chr6_-_75994631 0.120 NM_001143958
NM_018247
TMEM30A

transmembrane protein 30A

chr17_+_32582295 0.120 NM_002982
CCL2
chemokine (C-C motif) ligand 2
chr4_-_159093717 0.119 NM_016613
FAM198B
family with sequence similarity 198, member B
chr1_+_171060017 0.119 NM_001002294
NM_006894
FMO3

flavin containing monooxygenase 3

chr10_-_103815868 0.116 NM_024541
C10orf76
chromosome 10 open reading frame 76
chr12_-_9268440 0.115 A2M
alpha-2-macroglobulin
chr22_-_31688329 0.114 NM_001135911
NM_052880
PIK3IP1

phosphoinositide-3-kinase interacting protein 1

chr11_+_5641173 0.113 NM_001003827
TRIM34
tripartite motif containing 34
chr22_-_37164073 0.111 NM_001177702
IFT27
intraflagellar transport 27 homolog (Chlamydomonas)
chr14_+_95047730 0.109 NM_000624
SERPINA5
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr16_+_69726751 0.109 NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr17_-_29641094 0.109 NM_006495
EVI2B
ecotropic viral integration site 2B
chr17_+_34431219 0.108 NM_002984
CCL4
chemokine (C-C motif) ligand 4
chr16_+_22524843 0.107 NM_001135865
LOC100132247
NPIPL3
nuclear pore complex interacting protein related gene
nuclear pore complex interacting protein-like 3
chr18_-_52988916 0.107 NM_001243234
NM_001243235
TCF4

transcription factor 4

chr1_+_101185195 0.107 NM_001078
NM_001199834
NM_080682
VCAM1


vascular cell adhesion molecule 1


chr17_-_29641068 0.107 EVI2B
ecotropic viral integration site 2B
chrX_+_2959511 0.106 NM_001201539
ARSF
arylsulfatase F
chr14_-_70883680 0.106 NM_001202547
NM_001202548
NM_001202549
NM_018373
SYNJ2BP-COX16


SYNJ2BP
SYNJ2BP-COX16 readthrough


synaptojanin 2 binding protein
chr7_+_134212343 0.106 NM_020299
AKR1B10
aldo-keto reductase family 1, member B10 (aldose reductase)
chr15_-_34629044 0.105 NM_001042497
NM_133647
SLC12A6

solute carrier family 12 (potassium/chloride transporters), member 6

chr8_-_101315457 0.103 NM_015435
RNF19A
ring finger protein 19A
chr17_+_25958217 0.103 LGALS9
lectin, galactoside-binding, soluble, 9
chr12_-_53600999 0.102 NM_000889
ITGB7
integrin, beta 7
chr10_-_65028825 0.102 NM_004241
JMJD1C
jumonji domain containing 1C
chr17_+_34538464 0.102 NM_207007
NM_001001435
CCL4L2
CCL4L1
chemokine (C-C motif) ligand 4-like 2
chemokine (C-C motif) ligand 4-like 1
chr2_-_133429069 0.102 NM_001077427
LYPD1
LY6/PLAUR domain containing 1
chr13_-_33780142 0.100 NM_001243474
NM_052851
STARD13

StAR-related lipid transfer (START) domain containing 13


Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.