Motif ID: EWSR1-FLI1.p2

Z-value: 0.949


Transcription factors associated with EWSR1-FLI1.p2:

fusion protein between EWSR1 and FLI1 in an oncogenic event

Gene SymbolEntrez IDGene Name
EWSR1 2130 Ewing sarcoma breakpoint region 1
FLI1 2313 Friend leukemia virus integration 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
EWSR1chr22_+_29663997-0.214.4e-01Click!
FLI1chr11_+_1285637720.185.1e-01Click!


Activity profile for motif EWSR1-FLI1.p2.

activity profile for motif EWSR1-FLI1.p2


Sorted Z-values histogram for motif EWSR1-FLI1.p2

Sorted Z-values for motif EWSR1-FLI1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EWSR1-FLI1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_152009467 2.508 S100A11
S100 calcium binding protein A11
chr1_-_152009440 2.508 S100A11
S100 calcium binding protein A11
chr1_+_223889253 2.503 NM_001146068
CAPN2
calpain 2, (m/II) large subunit
chr1_-_152009406 2.458 S100A11
S100 calcium binding protein A11
chr7_+_16793320 2.410 NM_014399
TSPAN13
tetraspanin 13
chr1_-_68299047 2.328 NM_018841
GNG12
guanine nucleotide binding protein (G protein), gamma 12
chr1_+_186798031 1.908 NM_024420
PLA2G4A
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr6_-_10412606 1.809 NM_001032280
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr1_-_68697997 1.741 NM_001002292
NM_001193334
NM_024911
WLS


wntless homolog (Drosophila)


chr1_-_152009490 1.649 NM_005620
S100A11
S100 calcium binding protein A11
chrX_+_107683015 1.379 NM_000495
NM_033380
COL4A5

collagen, type IV, alpha 5

chr6_-_134496833 1.371 SGK1
serum/glucocorticoid regulated kinase 1
chr2_-_24307529 1.307 NM_004881
NM_147184
TP53I3

tumor protein p53 inducible protein 3

chr2_+_37571752 1.302 NM_012413
QPCT
glutaminyl-peptide cyclotransferase
chr6_-_132272311 1.255 NM_001901
CTGF
connective tissue growth factor
chr6_-_134497069 1.147 NM_001143678
SGK1
serum/glucocorticoid regulated kinase 1
chr3_-_42307661 1.082 NM_000729
CCK
cholecystokinin
chr17_+_48133357 0.995 ITGA3
integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
chr17_+_48133331 0.945 NM_002204
NM_005501
ITGA3

integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)

chr1_-_225840660 0.900 NM_001008493
NM_018212
ENAH

enabled homolog (Drosophila)


Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.