Motif ID: FOSL2.p2

Z-value: 1.088


Transcription factors associated with FOSL2.p2:

Gene SymbolEntrez IDGene Name
FOSL2 2355 FOS-like antigen 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
FOSL2chr2_+_28615695,
chr2_+_28616346
0.467.6e-02Click!


Activity profile for motif FOSL2.p2.

activity profile for motif FOSL2.p2


Sorted Z-values histogram for motif FOSL2.p2

Sorted Z-values for motif FOSL2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOSL2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_133494275 2.925 TF
transferrin
chr11_-_115088628 2.308 CADM1
cell adhesion molecule 1
chr7_+_23286277 2.139 NM_001005340
NM_002510
GPNMB

glycoprotein (transmembrane) nmb

chr8_-_27472188 2.106 CLU
clusterin
chr7_+_23286386 1.911 GPNMB
glycoprotein (transmembrane) nmb
chr7_+_23286390 1.910 GPNMB
glycoprotein (transmembrane) nmb
chr2_-_216259197 1.840 FN1
fibronectin 1
chr7_+_23286384 1.772 GPNMB
glycoprotein (transmembrane) nmb
chr18_+_21452981 1.693 NM_000227
NM_001127718
LAMA3

laminin, alpha 3

chr22_+_23040394 1.687 IGL@
immunoglobulin lambda locus
chr14_-_94855120 1.680 NM_000295
SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr17_+_80193649 1.648 NM_001206952
SLC16A3
solute carrier family 16, member 3 (monocarboxylic acid transporter 4)
chr14_-_94854910 1.635 SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr22_+_22758538 1.597


chr6_+_83072922 1.516 NM_006670
TPBG
trophoblast glycoprotein
chr22_+_22735134 1.509 CYAT1
immunoglobulin lambda light chain-like
chr11_+_121461070 1.446 SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr7_+_23286420 1.438 GPNMB
glycoprotein (transmembrane) nmb
chr6_-_30712294 1.408 NM_003897
IER3
immediate early response 3
chr11_+_101983170 1.358 NM_001195045
YAP1
Yes-associated protein 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 13 of 13 entries
Enrichment   P-value GO Accession GO Term
34.22 6.61e-05 GO:0002576 platelet degranulation
15.56 3.30e-03 GO:0006887 exocytosis
12.20 1.07e-02 GO:0030168 platelet activation
9.96 2.81e-02 GO:0032940 secretion by cell
8.92 9.50e-03 GO:0071702 organic substance transport
8.50 1.25e-02 GO:0046903 secretion
7.20 3.14e-02 GO:0007596 blood coagulation
7.20 3.14e-02 GO:0050817 coagulation
7.15 3.26e-02 GO:0007599 hemostasis
6.20 1.95e-02 GO:0006915 apoptosis
6.09 2.18e-02 GO:0012501 programmed cell death
5.98 2.45e-02 GO:0007155 cell adhesion
5.98 2.45e-02 GO:0022610 biological adhesion

Gene overrepresentation in compartment category:

Showing 1 to 16 of 16 entries
Enrichment   P-value GO Accession GO Term
43.10 1.35e-04 GO:0031093 platelet alpha granule lumen
42.20 1.48e-04 GO:0034774 secretory granule lumen
40.51 1.74e-04 GO:0060205 cytoplasmic membrane-bounded vesicle lumen
38.96 2.04e-04 GO:0031983 vesicle lumen
36.18 2.76e-04 GO:0031091 platelet alpha granule
17.49 4.57e-02 GO:0019717 synaptosome
14.09 1.53e-03 GO:0030141 stored secretory granule
6.01 6.77e-03 GO:0016023 cytoplasmic membrane-bounded vesicle
5.88 7.76e-03 GO:0031988 membrane-bounded vesicle
5.66 9.91e-03 GO:0031410 cytoplasmic vesicle
5.46 1.25e-02 GO:0031982 vesicle
4.23 8.11e-03 GO:0005887 integral to plasma membrane
4.18 8.96e-03 GO:0031226 intrinsic to plasma membrane
3.42 2.84e-03 GO:0044459 plasma membrane part
2.62 3.77e-03 GO:0005886 plasma membrane
2.59 4.54e-03 GO:0071944 cell periphery

Nothing significant found in function category.