Motif ID: FOXA2.p3

Z-value: 2.283


Transcription factors associated with FOXA2.p3:

Gene SymbolEntrez IDGene Name
FOXA2 3170 forkhead box A2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
FOXA2chr20_-_225648930.952.3e-08Click!


Activity profile for motif FOXA2.p3.

activity profile for motif FOXA2.p3


Sorted Z-values histogram for motif FOXA2.p3

Sorted Z-values for motif FOXA2.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXA2.p3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_69886112 12.807 NM_001075
NM_001144767
 UGT2B10

UDP glucuronosyltransferase 2 family, polypeptide B10

chr2_-_21225640 10.768 APOB
apolipoprotein B (including Ag(x) antigen)
chr4_+_6695565 9.226 NM_005980
 S100P
S100 calcium binding protein P
chr12_-_9268440 9.135 A2M
alpha-2-macroglobulin
chr12_-_9268513 9.098 A2M
alpha-2-macroglobulin
chr17_-_64225496 8.835 NM_000042
 APOH
apolipoprotein H (beta-2-glycoprotein I)
chr3_-_148939784 8.785 NM_000096
 CP
ceruloplasmin (ferroxidase)
chr4_-_70080448 8.724 NM_001073
 UGT2B11
UGT2B10
UDP glucuronosyltransferase 2 family, polypeptide B11
UDP glucuronosyltransferase 2 family, polypeptide B10
chr2_-_21266809 8.657 APOB
apolipoprotein B (including Ag(x) antigen)
chr17_-_26697224 7.996 VTN
vitronectin
chr1_-_169555624 7.843 F5
coagulation factor V (proaccelerin, labile factor)
chr10_+_7745229 7.749 NM_002216
 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr6_-_41715078 7.645 NM_001166424
NM_002630
 PGC

progastricsin (pepsinogen C)

chr22_+_21128378 7.588 NM_000185
 SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr17_-_26697310 7.498 VTN
vitronectin
chr1_-_169555710 7.388 NM_000130
 F5
coagulation factor V (proaccelerin, labile factor)
chr10_+_7745325 7.388 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr12_-_9268475 7.341 A2M
alpha-2-macroglobulin
chr10_+_7745341 7.239 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr10_+_7745284 7.038 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 6 of 6 entries
Enrichment   P-value GO Accession GO Term
21.82 2.01e-02 GO:0072378 blood coagulation, fibrin clot formation
20.78 2.46e-02 GO:0034367 macromolecular complex remodeling
20.78 2.46e-02 GO:0034368 protein-lipid complex remodeling
20.78 2.46e-02 GO:0034369 plasma lipoprotein particle remodeling
14.55 4.64e-05 GO:0072376 protein activation cascade
2.12 7.57e-03 GO:0065008 regulation of biological quality

Gene overrepresentation in compartment category:

Showing 1 to 15 of 15 entries
Enrichment   P-value GO Accession GO Term
29.75 1.44e-02 GO:0042627 chylomicron
24.24 2.28e-03 GO:0034361 very-low-density lipoprotein particle
24.24 2.28e-03 GO:0034385 triglyceride-rich lipoprotein particle
13.64 2.43e-02 GO:0032994 protein-lipid complex
13.64 2.43e-02 GO:0034358 plasma lipoprotein particle
12.59 9.22e-04 GO:0031983 vesicle lumen
11.61 8.21e-03 GO:0031093 platelet alpha granule lumen
11.37 9.10e-03 GO:0034774 secretory granule lumen
10.91 1.11e-02 GO:0060205 cytoplasmic membrane-bounded vesicle lumen
9.74 1.92e-02 GO:0031091 platelet alpha granule
5.15 2.99e-03 GO:0005792 microsome
4.99 3.96e-03 GO:0042598 vesicular fraction
4.27 2.57e-08 GO:0005615 extracellular space
3.66 1.60e-07 GO:0044421 extracellular region part
2.76 8.69e-07 GO:0005576 extracellular region

Gene overrepresentation in function category:

Showing 1 to 8 of 8 entries
Enrichment   P-value GO Accession GO Term
17.45 1.37e-02 GO:0015020 glucuronosyltransferase activity
12.32 2.75e-04 GO:0004867 serine-type endopeptidase inhibitor activity
9.57 3.19e-02 GO:0005319 lipid transporter activity
7.73 1.68e-03 GO:0004866 endopeptidase inhibitor activity
7.59 1.91e-03 GO:0030414 peptidase inhibitor activity
7.40 2.31e-03 GO:0061135 endopeptidase regulator activity
6.11 9.30e-03 GO:0061134 peptidase regulator activity
4.92 6.79e-03 GO:0004857 enzyme inhibitor activity