Motif ID: FOXO1,3,4.p2

Z-value: 1.499


Transcription factors associated with FOXO1,3,4.p2:

Gene SymbolEntrez IDGene Name
FOXO1 2308 forkhead box O1
FOXO3 2309 forkhead box O3
FOXO4 4303 forkhead box O4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
FOXO3chr6_+_1088820680.693.1e-03Click!
FOXO1chr13_-_41240607-0.224.2e-01Click!
FOXO4chrX_+_70315637-0.107.0e-01Click!


Activity profile for motif FOXO1,3,4.p2.

activity profile for motif FOXO1,3,4.p2


Sorted Z-values histogram for motif FOXO1,3,4.p2

Sorted Z-values for motif FOXO1,3,4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXO1,3,4.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_149086884 10.235 TM4SF1
transmembrane 4 L six family member 1
chr1_-_57044980 4.919 PPAP2B
phosphatidic acid phosphatase type 2B
chr1_-_57045235 4.771 NM_003713
 PPAP2B
phosphatidic acid phosphatase type 2B
chr9_+_75766794 4.450 ANXA1
annexin A1
chr1_-_57045129 3.702 PPAP2B
phosphatidic acid phosphatase type 2B
chr16_+_55512801 3.520 NM_004530
 MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr9_+_706744 3.476 NM_153186
 KANK1
KN motif and ankyrin repeat domains 1
chr18_-_21852189 2.723 NM_018030
 OSBPL1A
oxysterol binding protein-like 1A
chr8_-_13134028 2.716 DLC1
deleted in liver cancer 1
chr22_+_33196801 2.529 NM_000362
 TIMP3
TIMP metallopeptidase inhibitor 3
chr12_+_53491417 2.509 NM_002178
 IGFBP6
insulin-like growth factor binding protein 6
chr7_-_95064213 2.433 NM_000305
NM_001018161
 PON2

paraoxonase 2

chr1_-_57045214 2.419 PPAP2B
phosphatidic acid phosphatase type 2B
chr5_-_42811959 2.417 NM_001085486
NM_001093726
NM_005410
 SEPP1


selenoprotein P, plasma, 1


chr12_+_13043955 2.385 NM_003979
 GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr9_+_75766777 2.364 NM_000700
 ANXA1
annexin A1
chr4_-_80994183 2.246


chr6_+_121756744 2.192 NM_000165
 GJA1
gap junction protein, alpha 1, 43kDa
chr12_+_53491448 2.152 IGFBP6
insulin-like growth factor binding protein 6
chr7_+_134464417 2.064 CALD1
caldesmon 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 1 of 1 entries
Enrichment   P-value GO Accession GO Term
11.18 7.75e-03 GO:0030198 extracellular matrix organization

Gene overrepresentation in compartment category:

Showing 1 to 8 of 8 entries
Enrichment   P-value GO Accession GO Term
43.68 3.93e-03 GO:0005583 fibrillar collagen
19.42 5.27e-03 GO:0005581 collagen
11.45 2.56e-04 GO:0044420 extracellular matrix part
7.20 3.29e-05 GO:0005578 proteinaceous extracellular matrix
6.50 2.74e-05 GO:0031012 extracellular matrix
3.84 1.27e-05 GO:0044421 extracellular region part
3.14 2.25e-02 GO:0005615 extracellular space
3.04 5.49e-06 GO:0005576 extracellular region

Gene overrepresentation in function category:

Showing 1 to 9 of 9 entries
Enrichment   P-value GO Accession GO Term
80.06 5.01e-04 GO:0031994 insulin-like growth factor I binding
24.03 2.68e-02 GO:0005520 insulin-like growth factor binding
12.92 4.39e-03 GO:0004867 serine-type endopeptidase inhibitor activity
9.52 4.14e-03 GO:0019838 growth factor binding
8.51 7.77e-03 GO:0004866 endopeptidase inhibitor activity
8.37 8.57e-03 GO:0030414 peptidase inhibitor activity
8.15 9.89e-03 GO:0061135 endopeptidase regulator activity
6.73 2.84e-02 GO:0061134 peptidase regulator activity
5.78 7.52e-03 GO:0004857 enzyme inhibitor activity