Motif ID: GCUACAU

Z-value: 0.674


Mature miRNA associated with seed GCUACAU:

NamemiRBase Accession
hsa-miR-221 MIMAT0000278
hsa-miR-222 MIMAT0000279



Activity profile for motif GCUACAU.

activity profile for motif GCUACAU


Sorted Z-values histogram for motif GCUACAU

Sorted Z-values for motif GCUACAU



Network of associatons between targets according to the STRING database.



First level regulatory network of GCUACAU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_56652118 1.162 NM_173595
ANKRD52
ankyrin repeat domain 52
chr12_+_12869818 0.855 NM_004064
CDKN1B
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
chr17_-_47439326 0.771 NM_001145365
NM_014897
ZNF652

zinc finger protein 652

chr15_-_56535475 0.769 NM_022841
RFX7
regulatory factor X, 7
chr16_+_69599868 0.698 NM_001113178
NM_006599
NM_138713
NM_138714
NM_173214
NM_173215
NFAT5





nuclear factor of activated T-cells 5, tonicity-responsive





chr14_-_36278335 0.671 NM_014990
NM_194301
RALGAPA1

Ral GTPase activating protein, alpha subunit 1 (catalytic)

chr2_-_24149899 0.670 NM_001242338
NM_017552
ATAD2B

ATPase family, AAA domain containing 2B

chr5_-_175964223 0.617 NM_014901
RNF44
ring finger protein 44
chr18_-_11148760 0.573 NM_022068
PIEZO2
piezo-type mechanosensitive ion channel component 2
chr3_-_129612371 0.534 NM_001128224
TMCC1
transmembrane and coiled-coil domain family 1
chr3_-_129599220 0.533 NM_001017395
TMCC1
transmembrane and coiled-coil domain family 1
chr19_-_57336373 0.523 NM_001146186
PEG3
paternally expressed 3
chr16_+_68119211 0.497 NM_004555
NM_173163
NM_173165
NFATC3


nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3


chr14_-_95608054 0.490 NM_030621
DICER1
dicer 1, ribonuclease type III
chr22_+_21271619 0.481 NM_005207
CRKL
v-crk sarcoma virus CT10 oncogene homolog (avian)-like
chr1_+_114493766 0.481 NM_198269
HIPK1
homeodomain interacting protein kinase 1
chr14_+_74111577 0.473 NM_001201366
NM_031427
DNAL1

dynein, axonemal, light chain 1

chr11_-_35441099 0.466 NM_004171
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr5_-_171881421 0.455 NM_001017995
SH3PXD2B
SH3 and PX domains 2B
chr1_+_114496498 0.447 NM_181358
HIPK1
homeodomain interacting protein kinase 1
chr8_+_61591239 0.435 NM_017780
CHD7
chromodomain helicase DNA binding protein 7
chr6_+_16129285 0.427 NM_013262
MYLIP
myosin regulatory light chain interacting protein
chrX_+_152953751 0.418 NM_001142805
NM_005629
SLC6A8

solute carrier family 6 (neurotransmitter transporter, creatine), member 8

chr14_-_95599794 0.396 NM_001195573
DICER1
dicer 1, ribonuclease type III
chr7_+_112063131 0.395 NM_001007245
NM_001197080
IFRD1

interferon-related developmental regulator 1

chr11_-_35441501 0.391 NM_001195728
NM_001252652
SLC1A2

solute carrier family 1 (glial high affinity glutamate transporter), member 2

chr3_+_38495778 0.389 NM_001106
ACVR2B
activin A receptor, type IIB
chr8_+_11561710 0.387 NM_002052
GATA4
GATA binding protein 4
chr2_-_152955502 0.385 NM_000726
NM_001145798
CACNB4

calcium channel, voltage-dependent, beta 4 subunit

chrX_+_152954965 0.377 NM_001142806
SLC6A8
solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chr2_+_178257371 0.375 NM_003659
AGPS
alkylglycerone phosphate synthase
chr21_+_40177847 0.358 NM_005239
ETS2
v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)
chr16_-_73092533 0.357 NM_001164766
ZFHX3
zinc finger homeobox 3
chr7_+_94285676 0.356 NM_001172437
NM_001172438
PEG10

paternally expressed 10

chr2_+_111878450 0.350 NM_001204106
NM_001204107
NM_001204108
NM_001204109
NM_001204110
NM_001204111
NM_001204112
NM_001204113
NM_006538
NM_138621
NM_138622
NM_138623
NM_138624
NM_138625
NM_138626
NM_138627
NM_207002
NM_207003
BCL2L11

















BCL2-like 11 (apoptosis facilitator)

















chr6_-_2245655 0.335 NM_001500
GMDS
GDP-mannose 4,6-dehydratase
chr2_+_64681270 0.328 NM_014181
LGALSL
lectin, galactoside-binding-like
chr2_+_48541767 0.327 NM_002158
FOXN2
forkhead box N2
chr9_-_112260529 0.324 NM_001145368
NM_002829
PTPN3

protein tyrosine phosphatase, non-receptor type 3

chr13_+_50202434 0.318 NM_138450
ARL11
ADP-ribosylation factor-like 11
chr7_+_94285620 0.316 NM_001040152
NM_001184961
NM_001184962
NM_015068
PEG10



paternally expressed 10



chr2_-_152955208 0.313 NM_001005746
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr14_-_95623665 0.307 NM_177438
DICER1
dicer 1, ribonuclease type III
chr9_-_112213663 0.303 NM_001145369
NM_001145370
PTPN3

protein tyrosine phosphatase, non-receptor type 3

chr3_+_140660639 0.294 NM_001104647
NM_018155
SLC25A36

solute carrier family 25, member 36

chr2_-_43453737 0.288 NM_006887
ZFP36L2
zinc finger protein 36, C3H type-like 2
chr2_+_110371887 0.280 NM_023016
ANKRD57
ankyrin repeat domain 57
chr9_+_103791030 0.277 NM_207299
LPPR1
lipid phosphate phosphatase-related protein type 1
chr2_-_68479481 0.277 NM_000945
PPP3R1
protein phosphatase 3, regulatory subunit B, alpha
chr16_-_30798206 0.272 NM_001080417
ZNF629
zinc finger protein 629
chr16_-_73082169 0.270 NM_006885
ZFHX3
zinc finger homeobox 3
chr7_+_112092112 0.268 NM_001197079
IFRD1
interferon-related developmental regulator 1
chr7_+_112090463 0.266 NM_001550
IFRD1
interferon-related developmental regulator 1
chr2_-_152830448 0.265 NM_001005747
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr9_+_103947316 0.262 NM_017753
LPPR1
lipid phosphate phosphatase-related protein type 1
chr1_+_179923870 0.261 NM_014810
CEP350
centrosomal protein 350kDa
chrX_+_24073060 0.261 NM_001415
EIF2S3
eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
chr1_+_167298280 0.261 NM_001198783
POU2F1
POU class 2 homeobox 1
chr17_+_61627818 0.256 NM_005828
DCAF7
DDB1 and CUL4 associated factor 7
chr6_+_163835668 0.248 NM_006775
NM_206853
NM_206854
NM_206855
QKI



QKI, KH domain containing, RNA binding



chr3_+_10183318 0.244 NM_000551
NM_198156
VHL

von Hippel-Lindau tumor suppressor

chr12_+_69864065 0.242 NM_001042555
NM_006654
FRS2

fibroblast growth factor receptor substrate 2

chr1_+_116916488 0.239 NM_001160233
ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr6_+_7107986 0.231 NM_001003698
NM_001003699
NM_001003700
RREB1


ras responsive element binding protein 1


chr12_-_102872329 0.231 NM_001111284
IGF1
insulin-like growth factor 1 (somatomedin C)
chr18_-_19284737 0.229 NM_138340
ABHD3
abhydrolase domain containing 3
chr1_-_117210301 0.225 NM_001007237
NM_001542
IGSF3

immunoglobulin superfamily, member 3

chr8_+_28748030 0.223 NM_024567
HMBOX1
homeobox containing 1
chr1_+_116925991 0.222 NM_001160234
ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chrX_+_146993450 0.218 NM_001185075
NM_001185076
NM_001185081
NM_001185082
NM_002024
FMR1




fragile X mental retardation 1




chr6_-_111136407 0.217 NM_015076
CDK19
cyclin-dependent kinase 19
chr10_+_74033676 0.217 NM_019058
DDIT4
DNA-damage-inducible transcript 4
chr9_-_115095933 0.215 NM_001163788
NM_001163790
NM_001244896
NM_001244897
NM_005156
PTBP3




polypyrimidine tract binding protein 3




chr20_+_31367637 0.211 NM_175850
DNMT3B
DNA (cytosine-5-)-methyltransferase 3 beta
chr10_+_114709963 0.211 NM_001146274
NM_001146283
NM_001146284
NM_001146285
NM_001146286
NM_001198525
NM_001198526
NM_001198527
NM_001198528
NM_001198529
NM_001198530
NM_001198531
NM_030756
TCF7L2












transcription factor 7-like 2 (T-cell specific, HMG-box)












chr20_+_31350190 0.209 NM_001207055
NM_001207056
NM_006892
NM_175848
NM_175849
DNMT3B




DNA (cytosine-5-)-methyltransferase 3 beta




chr6_+_47445440 0.208 NM_012120
CD2AP
CD2-associated protein
chr1_+_116915794 0.207 NM_000701
ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr10_-_118765087 0.205 NM_001127211
NM_018330
KIAA1598

KIAA1598

chr3_+_50304989 0.202 NM_001005914
NM_004636
SEMA3B

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B

chr4_+_184020343 0.199 NM_024949
WWC2
WW and C2 domain containing 2
chr15_-_70390229 0.195 NM_001105192
NM_005078
NM_020908
TLE3


transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)


chr9_-_112191105 0.192 NM_001145371
NM_001145372
PTPN3

protein tyrosine phosphatase, non-receptor type 3

chr3_+_171758289 0.192 NM_001135095
FNDC3B
fibronectin type III domain containing 3B
chr16_-_2318412 0.189 NM_080594
RNPS1
RNA binding protein S1, serine-rich domain
chr10_+_102106771 0.188 NM_005063
SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chr15_+_44829265 0.187 NM_003758
EIF3J
eukaryotic translation initiation factor 3, subunit J
chr7_-_139477437 0.186 NM_001113239
NM_022740
HIPK2

homeodomain interacting protein kinase 2

chr1_+_150980895 0.186 NM_021222
PRUNE
prune homolog (Drosophila)
chr4_-_23891608 0.185 NM_013261
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr6_+_150920998 0.182 NM_001029884
PLEKHG1
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chrX_-_110655384 0.180 NM_178151
NM_001195553
NM_178152
NM_178153
DCX



doublecortin



chr1_-_245027808 0.178 NM_004501
NM_031844
HNRNPU

heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)

chrX_-_50557019 0.177 NM_020717
SHROOM4
shroom family member 4
chr9_-_5833072 0.177 NM_024896
ERMP1
endoplasmic reticulum metallopeptidase 1
chr12_-_53994783 0.176 NM_001130059
ATF7
activating transcription factor 7
chr1_+_167189948 0.176 NM_001198786
NM_002697
POU2F1

POU class 2 homeobox 1

chr5_-_138211054 0.176 NM_015564
LRRTM2
leucine rich repeat transmembrane neuronal 2
chr17_-_76356153 0.175 NM_003955
SOCS3
suppressor of cytokine signaling 3
chr17_-_27169740 0.175 NM_001077498
NM_018182
C17orf63

chromosome 17 open reading frame 63

chr9_-_74383301 0.174 NM_001135820
NM_013390
TMEM2

transmembrane protein 2

chr14_-_37641864 0.173 NM_001171170
NM_030631
SLC25A21

solute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 21

chr19_+_18942742 0.170 NM_002911
UPF1
UPF1 regulator of nonsense transcripts homolog (yeast)
chr16_-_23521803 0.170 NM_015044
GGA2
golgi-associated, gamma adaptin ear containing, ARF binding protein 2
chr1_+_114471995 0.169 NM_152696
NM_198268
HIPK1

homeodomain interacting protein kinase 1

chr2_+_109335906 0.166 NM_006267
RANBP2
RAN binding protein 2
chr3_-_13114547 0.162 NM_001134382
IQSEC1
IQ motif and Sec7 domain 1
chr1_+_10270680 0.161 NM_015074
NM_183416
KIF1B

kinesin family member 1B

chr10_+_5488521 0.161 NM_005863
NET1
neuroepithelial cell transforming 1
chr10_-_11574273 0.161 NM_001080491
USP6NL
USP6 N-terminal like
chr8_+_28747885 0.161 NM_001135726
HMBOX1
homeobox containing 1
chr1_+_220863627 0.160 NM_024709
C1orf115
chromosome 1 open reading frame 115
chr2_-_65593866 0.160 NM_001128210
SPRED2
sprouty-related, EVH1 domain containing 2
chr3_-_184870727 0.160 NM_001025266
C3orf70
chromosome 3 open reading frame 70
chr1_+_26438267 0.156 NM_001243533
NM_152835
PDIK1L

PDLIM1 interacting kinase 1 like

chr5_+_161277702 0.155 NM_001127648
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr4_+_38665587 0.154 NM_016531
KLF3
Kruppel-like factor 3 (basic)
chr16_-_2317827 0.152 NM_006711
RNPS1
RNA binding protein S1, serine-rich domain
chr10_+_5454516 0.151 NM_001047160
NET1
neuroepithelial cell transforming 1
chr14_-_34931413 0.150 NM_138288
SPTSSA
serine palmitoyltransferase, small subunit A
chr17_-_37607314 0.145 NM_004774
MED1
mediator complex subunit 1
chr2_-_61697846 0.145 NM_014709
USP34
ubiquitin specific peptidase 34
chr2_+_27274490 0.143 NM_001035507
NM_021831
AGBL5

ATP/GTP binding protein-like 5

chr10_-_6622200 0.142 NM_001242413
NM_006257
PRKCQ

protein kinase C, theta

chrX_-_110654373 0.141 NM_000555
DCX
doublecortin
chr11_+_9596233 0.140 NM_001143976
WEE1
WEE1 homolog (S. pombe)
chr1_+_226250407 0.139 NM_002107
H3F3A
H3 histone, family 3A
chr6_-_16761600 0.139 NM_000332
NM_001128164
ATXN1

ataxin 1

chr7_-_44924946 0.139 NM_033224
PURB
purine-rich element binding protein B
chr11_-_70507911 0.138 NM_133266
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr2_+_86947387 0.135 NM_022780
RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr3_+_169684549 0.134 NM_003262
SEC62
SEC62 homolog (S. cerevisiae)
chr2_-_65659634 0.133 NM_181784
SPRED2
sprouty-related, EVH1 domain containing 2
chr10_-_75910525 0.132 NM_012095
NM_207012
AP3M1

adaptor-related protein complex 3, mu 1 subunit

chr6_-_86352635 0.130 NM_001159673
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr2_+_177053306 0.130 NM_024501
HOXD1
homeobox D1
chrX_+_68725077 0.129 NM_015686
FAM155B
family with sequence similarity 155, member B
chr2_-_55646946 0.129 NM_001135597
NM_018084
CCDC88A

coiled-coil domain containing 88A

chr7_-_92463211 0.128 NM_001259
CDK6
cyclin-dependent kinase 6
chr1_+_169075869 0.128 NM_001677
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr12_-_115121939 0.127 NM_005996
NM_016569
TBX3

T-box 3

chr6_+_24775154 0.127 NM_001251989
NM_001251990
NM_015895
GMNN


geminin, DNA replication inhibitor


chr14_-_21899866 0.126 NM_001170629
CHD8
chromodomain helicase DNA binding protein 8
chr1_-_10856704 0.123 NM_001079843
NM_017766
CASZ1

castor zinc finger 1

chr11_-_70935807 0.123 NM_012309
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr12_+_5019048 0.121 NM_000217
KCNA1
potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
chr6_+_7107799 0.121 NM_001168344
RREB1
ras responsive element binding protein 1
chr2_-_128100673 0.121 NM_006609
MAP3K2
mitogen-activated protein kinase kinase kinase 2
chr6_+_36853639 0.119 NM_152734
C6orf89
chromosome 6 open reading frame 89
chr10_-_11653529 0.118 NM_014688
USP6NL
USP6 N-terminal like
chr1_-_200589856 0.117 NM_014875
KIF14
kinesin family member 14
chr2_+_60983354 0.117 NM_022894
PAPOLG
poly(A) polymerase gamma
chr1_-_47695442 0.117 NM_003189
TAL1
T-cell acute lymphocytic leukemia 1
chr1_-_27816676 0.117 NM_001201404
NM_006990
WASF2

WAS protein family, member 2

chr6_-_86352564 0.117 NM_001159674
NM_001253771
SYNCRIP

synaptotagmin binding, cytoplasmic RNA interacting protein

chr2_-_2334887 0.117 NM_015025
MYT1L
myelin transcription factor 1-like
chr10_-_99094427 0.117 NM_012083
FRAT2
frequently rearranged in advanced T-cell lymphomas 2
chr6_+_20402040 0.116 NM_001949
E2F3
E2F transcription factor 3
chr6_+_45296053 0.116 NM_001015051
NM_001024630
RUNX2

runt-related transcription factor 2

chr3_-_182698291 0.116 NM_020640
DCUN1D1
DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)
chr11_-_83984230 0.115 NM_001142700
DLG2
discs, large homolog 2 (Drosophila)
chr11_+_9595183 0.115 NM_003390
WEE1
WEE1 homolog (S. pombe)
chr16_-_56485113 0.115 NM_007006
NUDT21
nudix (nucleoside diphosphate linked moiety X)-type motif 21
chr4_-_176734181 0.113 NM_201591
GPM6A
glycoprotein M6A
chr11_+_32914359 0.113 NM_001076786
QSER1
glutamine and serine rich 1
chr6_-_79787939 0.111 NM_017934
PHIP
pleckstrin homology domain interacting protein
chr11_-_118927872 0.110 NM_006389
NM_001130991
HYOU1

hypoxia up-regulated 1

chr5_+_161274939 0.109 NM_001127644
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chrX_+_70315637 0.109 NM_001170931
NM_005938
FOXO4

forkhead box O4

chr1_+_28764660 0.109 NM_023923
PHACTR4
phosphatase and actin regulator 4
chr14_-_21905401 0.108 NM_020920
CHD8
chromodomain helicase DNA binding protein 8
chr20_-_48530275 0.106 NM_001135773
SPATA2
spermatogenesis associated 2
chr3_+_183353355 0.106 NM_017644
KLHL24
kelch-like 24 (Drosophila)
chr4_+_160188997 0.106 NM_014247
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr5_-_168006413 0.105 NM_024594
PANK3
pantothenate kinase 3
chr11_+_45868668 0.105 NM_001127457
CRY2
cryptochrome 2 (photolyase-like)
chr7_+_16793320 0.104 NM_014399
TSPAN13
tetraspanin 13
chr20_+_56964162 0.102 NM_001195677
NM_004738
VAPB

VAMP (vesicle-associated membrane protein)-associated protein B and C

chr20_-_16553911 0.101 NM_001199865
NM_001199866
NM_024704
KIF16B


kinesin family member 16B


chr1_+_24286300 0.100 NM_017761
PNRC2
proline-rich nuclear receptor coactivator 2
chr2_-_20424627 0.099 NM_002997
SDC1
syndecan 1
chr10_-_94003002 0.099 NM_001178137
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr13_-_45563554 0.098 NM_012345
NUFIP1
nuclear fragile X mental retardation protein interacting protein 1
chr12_+_94542239 0.098 NM_005761
PLXNC1
plexin C1
chr16_-_87525317 0.098 NM_015144
ZCCHC14
zinc finger, CCHC domain containing 14
chr11_-_94226906 0.098 NM_005590
NM_005591
MRE11A

MRE11 meiotic recombination 11 homolog A (S. cerevisiae)

chrX_+_68835910 0.098 NM_001005609
NM_001005610
NM_001005612
NM_001005613
NM_001399
EDA




ectodysplasin A




chr17_+_36861857 0.097 NM_005937
MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr4_-_89744154 0.096 NM_001015045
FAM13A
family with sequence similarity 13, member A
chr5_+_67586466 0.095 NM_181504
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr7_-_92465929 0.095 NM_001145306
CDK6
cyclin-dependent kinase 6
chr3_-_11761946 0.094 NM_014667
VGLL4
vestigial like 4 (Drosophila)
chr3_+_171757413 0.094 NM_022763
FNDC3B
fibronectin type III domain containing 3B
chr22_+_40573879 0.093 NM_001162501
NM_015088
TNRC6B

trinucleotide repeat containing 6B

chr8_+_42752019 0.092 NM_032410
HOOK3
hook homolog 3 (Drosophila)
chr8_+_106331146 0.092 NM_012082
ZFPM2
zinc finger protein, multitype 2
chr10_-_115613858 0.092 NM_014881
DCLRE1A
DNA cross-link repair 1A
chr3_-_11685395 0.092 NM_001128219
VGLL4
vestigial like 4 (Drosophila)
chr10_+_120789227 0.092 NM_199461
NANOS1
nanos homolog 1 (Drosophila)
chr4_+_144257982 0.091 NM_002039
NM_207123
GAB1

GRB2-associated binding protein 1


Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.