Motif ID: GCUGGUG

Z-value: 0.920


Mature miRNA associated with seed GCUGGUG:

NamemiRBase Accession
hsa-miR-138 MIMAT0000430



Activity profile for motif GCUGGUG.

activity profile for motif GCUGGUG


Sorted Z-values histogram for motif GCUGGUG

Sorted Z-values for motif GCUGGUG



Network of associatons between targets according to the STRING database.



First level regulatory network of GCUGGUG

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_173176314 1.620 NM_003326
TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr7_-_103629962 1.470 NM_005045
NM_173054
RELN

reelin

chr16_-_29910340 1.311 NM_001114099
NM_001114100
NM_001243332
NM_001243333
NM_012410
NM_201575
SEZ6L2





seizure related 6 homolog (mouse)-like 2





chr4_-_23891608 1.217 NM_013261
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr11_-_70507911 1.200 NM_133266
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr11_-_70935807 1.189 NM_012309
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr20_-_3149070 1.135 NM_014731
ProSAPiP1
ProSAPiP1 protein
chr6_+_107811272 1.132 NM_018013
SOBP
sine oculis binding protein homolog (Drosophila)
chr2_+_7057471 1.091 NM_014746
RNF144A
ring finger protein 144A
chr9_-_140353785 1.050 NM_001130969
NM_001130970
NM_001130971
NM_001178064
NM_015537
NELF




nasal embryonic LHRH factor




chr16_-_57318574 0.985 NM_015993
PLLP
plasmolipin
chr16_+_69599868 0.966 NM_001113178
NM_006599
NM_138713
NM_138714
NM_173214
NM_173215
NFAT5





nuclear factor of activated T-cells 5, tonicity-responsive





chrX_+_9432980 0.962 NM_005647
TBL1X
transducin (beta)-like 1X-linked
chr3_-_13008959 0.957 NM_014869
IQSEC1
IQ motif and Sec7 domain 1
chr3_-_13114547 0.909 NM_001134382
IQSEC1
IQ motif and Sec7 domain 1
chr7_+_130131921 0.907 NM_002402
MEST
mesoderm specific transcript homolog (mouse)
chrX_+_9431314 0.905 NM_001139466
NM_001139467
NM_001139468
TBL1X


transducin (beta)-like 1X-linked


chr7_+_130126035 0.891 NM_177524
MEST
mesoderm specific transcript homolog (mouse)
chr20_+_306205 0.864 NM_006943
SOX12
SRY (sex determining region Y)-box 12
chr2_-_11484699 0.829 NM_004850
ROCK2
Rho-associated, coiled-coil containing protein kinase 2
chrX_+_152954965 0.801 NM_001142806
SLC6A8
solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chr2_-_97535669 0.793 NM_017789
SEMA4C
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr3_+_38495778 0.791 NM_001106
ACVR2B
activin A receptor, type IIB
chr7_+_130131172 0.780 NM_177525
MEST
mesoderm specific transcript homolog (mouse)
chr9_-_36401149 0.777 NM_194330
RNF38
ring finger protein 38
chr3_-_53381533 0.777 NM_018403
DCP1A
DCP1 decapping enzyme homolog A (S. cerevisiae)
chr5_-_74162614 0.775 NM_015566
FAM169A
family with sequence similarity 169, member A
chr10_+_80828776 0.754 NM_020338
ZMIZ1
zinc finger, MIZ-type containing 1
chr11_-_75062650 0.736 NM_004041
NM_020251
ARRB1

arrestin, beta 1

chr7_-_137686814 0.701 NM_001253775
NM_194071
CREB3L2

cAMP responsive element binding protein 3-like 2

chr9_-_36400212 0.693 NM_022781
NM_194329
RNF38

ring finger protein 38

chr11_-_78128852 0.689 NM_080491
GAB2
GRB2-associated binding protein 2
chr2_-_101034049 0.688 NM_004854
CHST10
carbohydrate sulfotransferase 10
chr9_-_36400817 0.681 NM_194328
NM_194332
RNF38

ring finger protein 38

chrX_+_152953751 0.674 NM_001142805
NM_005629
SLC6A8

solute carrier family 6 (neurotransmitter transporter, creatine), member 8

chr14_-_53417808 0.654 NM_001134999
NM_001135000
NM_006832
FERMT2


fermitin family member 2


chr16_+_58549382 0.615 NM_001160305
NM_024860
SETD6

SET domain containing 6

chr16_-_87525317 0.604 NM_015144
ZCCHC14
zinc finger, CCHC domain containing 14
chr12_+_132195632 0.603 NM_004592
SFSWAP
splicing factor, suppressor of white-apricot homolog (Drosophila)
chr9_+_706744 0.583 NM_153186
KANK1
KN motif and ankyrin repeat domains 1
chr9_-_95896498 0.583 NM_004148
NINJ1
ninjurin 1
chr11_-_65381641 0.580 NM_002419
MAP3K11
mitogen-activated protein kinase kinase kinase 11
chr11_-_78052925 0.579 NM_012296
GAB2
GRB2-associated binding protein 2
chr8_-_53626991 0.576 NM_001083617
NM_014781
RB1CC1

RB1-inducible coiled-coil 1

chr13_-_52585472 0.553 NM_000053
NM_001005918
NM_001243182
ATP7B


ATPase, Cu++ transporting, beta polypeptide


chr9_+_504661 0.550 NM_015158
KANK1
KN motif and ankyrin repeat domains 1
chr4_-_186578122 0.549 NM_001145674
NM_001145675
SORBS2

sorbin and SH3 domain containing 2

chr4_-_186877869 0.545 NM_021069
SORBS2
sorbin and SH3 domain containing 2
chr5_+_156693051 0.541 NM_001037333
NM_001037332
CYFIP2

cytoplasmic FMR1 interacting protein 2

chr6_+_87865261 0.537 NM_015021
ZNF292
zinc finger protein 292
chr2_-_240322620 0.528 NM_006037
HDAC4
histone deacetylase 4
chr4_+_41614911 0.525 NM_001112719
NM_001112720
LIMCH1

LIM and calponin homology domains 1

chr4_-_186697065 0.516 NM_001145673
SORBS2
sorbin and SH3 domain containing 2
chr6_+_158733691 0.512 NM_001007466
NM_020245
TULP4

tubby like protein 4

chr10_-_65225605 0.506 NM_032776
JMJD1C
jumonji domain containing 1C
chr2_+_86947387 0.503 NM_022780
RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr6_+_34759743 0.501 NM_017754
UHRF1BP1
UHRF1 binding protein 1
chr10_+_69644938 0.489 NM_001142498
SIRT1
sirtuin 1
chr4_-_186733372 0.484 NM_003603
NM_001145670
SORBS2

sorbin and SH3 domain containing 2

chr2_+_10184371 0.483 NM_001177718
KLF11
Kruppel-like factor 11
chr4_-_186732047 0.478 NM_001145672
SORBS2
sorbin and SH3 domain containing 2
chr2_+_10183630 0.476 NM_003597
NM_001177716
KLF11

Kruppel-like factor 11

chr13_+_36050885 0.472 NM_001204197
NBEA
neurobeachin
chr15_-_79237353 0.464 NM_004390
CTSH
cathepsin H
chr19_+_34663311 0.463 NM_001114093
NM_015578
LSM14A

LSM14A, SCD6 homolog A (S. cerevisiae)

chr4_-_186732208 0.462 NM_001145671
SORBS2
sorbin and SH3 domain containing 2
chr11_-_128894008 0.458 NM_014715
ARHGAP32
Rho GTPase activating protein 32
chr10_-_65028825 0.457 NM_004241
JMJD1C
jumonji domain containing 1C
chr15_-_75743776 0.446 NM_015477
SIN3A
SIN3 transcription regulator homolog A (yeast)
chr11_-_115375065 0.444 NM_001098517
NM_014333
CADM1

cell adhesion molecule 1

chr1_+_93544786 0.439 NM_001164391
NM_001164392
NM_001164393
NM_007358
MTF2



metal response element binding transcription factor 2



chr10_+_69644341 0.436 NM_012238
SIRT1
sirtuin 1
chr1_-_109940497 0.431 NM_002959
SORT1
sortilin 1
chr2_-_85788644 0.430 NM_000821
NM_001142269
GGCX

gamma-glutamyl carboxylase

chr19_+_19496629 0.430 NM_017660
GATAD2A
GATA zinc finger domain containing 2A
chr14_-_25519076 0.429 NM_014178
STXBP6
syntaxin binding protein 6 (amisyn)
chr5_-_115910406 0.426 NM_020796
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr11_-_129062092 0.414 NM_001142685
ARHGAP32
Rho GTPase activating protein 32
chr2_+_28615771 0.414 NM_005253
FOSL2
FOS-like antigen 2
chr20_-_4982133 0.414 NM_005116
SLC23A2
solute carrier family 23 (nucleobase transporters), member 2
chr1_+_36348795 0.413 NM_012199
EIF2C1
eukaryotic translation initiation factor 2C, 1
chr11_+_111944967 0.411 NM_001082969
NM_001082970
NM_018195
C11orf57


chromosome 11 open reading frame 57


chr4_+_41362750 0.406 NM_001112717
NM_001112718
NM_014988
LIMCH1


LIM and calponin homology domains 1


chr1_+_204042191 0.398 NM_005686
SOX13
SRY (sex determining region Y)-box 13
chr13_+_35516390 0.383 NM_015678
NBEA
neurobeachin
chr13_-_76055872 0.357 NM_014832
TBC1D4
TBC1 domain family, member 4
chr22_-_50746000 0.353 NM_012401
PLXNB2
plexin B2
chr3_-_142166782 0.350 NM_001042604
NM_019001
XRN1

5'-3' exoribonuclease 1

chr2_+_121103670 0.350 NM_002193
INHBB
inhibin, beta B
chr15_-_52587851 0.346 NM_018728
MYO5C
myosin VC
chr1_+_53068042 0.343 NM_015696
GPX6
GPX7
glutathione peroxidase 6 (olfactory)
glutathione peroxidase 7
chr10_+_97889467 0.342 NM_014803
ZNF518A
zinc finger protein 518A
chr5_+_156696351 0.338 NM_014376
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr2_+_24807345 0.335 NM_003743
NM_147223
NM_147233
NCOA1


nuclear receptor coactivator 1


chr6_+_64281910 0.335 NM_003463
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr6_-_111136407 0.333 NM_015076
CDK19
cyclin-dependent kinase 19
chr17_+_74864427 0.331 NM_001199172
NM_144677
MGAT5B

mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B

chr2_+_109150807 0.325 NM_001193483
LIMS1
LIM and senescent cell antigen-like domains 1
chr9_-_127905715 0.324 NM_001144877
NM_173690
SCAI

suppressor of cancer cell invasion

chr1_-_92351613 0.323 NM_001195683
NM_003243
TGFBR3

transforming growth factor, beta receptor III

chr20_+_1099216 0.322 NM_006814
PSMF1
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr1_+_114496498 0.316 NM_181358
HIPK1
homeodomain interacting protein kinase 1
chr1_+_33116748 0.315 NM_001135255
NM_005610
NM_001135256
RBBP4


retinoblastoma binding protein 4


chr3_+_140660639 0.308 NM_001104647
NM_018155
SLC25A36

solute carrier family 25, member 36

chr20_+_32077904 0.302 NM_001032999
CBFA2T2
core-binding factor, runt domain, alpha subunit 2; translocated to, 2
chr1_-_23886284 0.293 NM_002167
ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr1_-_92371558 0.289 NM_001195684
TGFBR3
transforming growth factor, beta receptor III
chrX_-_118827322 0.285 NM_015129
NM_145799
NM_145800
NM_145802
SEPT6



septin 6



chr8_-_134584012 0.285 NM_003033
NM_173344
ST3GAL1

ST3 beta-galactoside alpha-2,3-sialyltransferase 1

chr17_+_38465422 0.284 NM_000964
RARA
retinoic acid receptor, alpha
chr17_-_58603492 0.283 NM_006380
APPBP2
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr20_+_54933982 0.283 NM_080821
FAM210B
family with sequence similarity 210, member B
chr16_-_18937722 0.277 NM_015092
SMG1
smg-1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)
chr2_+_148602569 0.274 NM_001616
ACVR2A
activin A receptor, type IIA
chr20_+_47538211 0.274 NM_006420
ARFGEF2
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr5_+_179159799 0.273 NM_014757
MAML1
mastermind-like 1 (Drosophila)
chrX_-_131623994 0.268 NM_001170704
MBNL3
muscleblind-like 3 (Drosophila)
chr19_-_46234126 0.266 NM_001080469
FBXO46
F-box protein 46
chr1_+_114493766 0.263 NM_198269
HIPK1
homeodomain interacting protein kinase 1
chr22_-_43343046 0.261 NM_007229
PACSIN2
protein kinase C and casein kinase substrate in neurons 2
chr12_+_111843743 0.260 NM_005475
SH2B3
SH2B adaptor protein 3
chr2_+_219263060 0.259 NM_001206878
CTDSP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chrX_-_131573638 0.256 NM_018388
NM_133486
MBNL3

muscleblind-like 3 (Drosophila)

chr3_+_98451537 0.254 NM_006100
ST3GAL6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr20_+_3827421 0.252 NM_001206491
NM_020746
MAVS

mitochondrial antiviral signaling protein

chr12_-_23737507 0.248 NM_178010
SOX5
SRY (sex determining region Y)-box 5
chrX_-_131547536 0.248 NM_001170701
NM_001170702
NM_001170703
MBNL3


muscleblind-like 3 (Drosophila)


chr3_-_48700317 0.244 NM_001407
CELSR3
cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)
chr22_+_39101806 0.239 NM_004286
GTPBP1
GTP binding protein 1
chr8_+_106331146 0.239 NM_012082
ZFPM2
zinc finger protein, multitype 2
chr12_-_24102563 0.233 NM_006940
SOX5
SRY (sex determining region Y)-box 5
chr20_-_4990913 0.231 NM_203327
SLC23A2
solute carrier family 23 (nucleobase transporters), member 2
chr2_+_109271267 0.229 NM_001193485
LIMS1
LIM and senescent cell antigen-like domains 1
chr1_-_150241409 0.228 NM_001077628
NM_001243771
NM_001243772
NM_016022
APH1A



anterior pharynx defective 1 homolog A (C. elegans)



chr19_+_35521591 0.227 NM_001037
NM_199037
SCN1B

sodium channel, voltage-gated, type I, beta

chr4_-_140060601 0.226 NM_201999
ELF2
E74-like factor 2 (ets domain transcription factor)
chr21_-_28339405 0.225 NM_007038
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr9_-_73029539 0.223 NM_001206
KLF9
Kruppel-like factor 9
chr22_-_43411156 0.221 NM_001184970
PACSIN2
protein kinase C and casein kinase substrate in neurons 2
chr10_-_735522 0.221 NM_014974
DIP2C
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr20_-_30795346 0.219 NM_002657
PLAGL2
pleiomorphic adenoma gene-like 2
chr4_-_140005464 0.217 NM_006874
ELF2
E74-like factor 2 (ets domain transcription factor)
chr19_-_1652327 0.217 NM_003200
TCF3
transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)
chr12_-_24715349 0.217 NM_152989
SOX5
SRY (sex determining region Y)-box 5
chr10_+_72163860 0.216 NM_004096
EIF4EBP2
eukaryotic translation initiation factor 4E binding protein 2
chr3_+_138066489 0.216 NM_001252091
NM_012219
MRAS

muscle RAS oncogene homolog

chr1_-_109935869 0.210 NM_001205228
SORT1
sortilin 1
chr15_-_68498373 0.210 NM_001031733
NM_033429
CALML4

calmodulin-like 4

chr12_-_498428 0.208 NM_001042603
KDM5A
lysine (K)-specific demethylase 5A
chr17_-_56065596 0.207 NM_007146
VEZF1
vascular endothelial zinc finger 1
chr5_+_154238196 0.207 NM_004779
CNOT8
CCR4-NOT transcription complex, subunit 8
chr3_+_23987514 0.207 NM_001145425
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr2_+_27309610 0.205 NM_000221
NM_006488
KHK

ketohexokinase (fructokinase)

chr17_+_38498270 0.203 NM_001024809
RARA
retinoic acid receptor, alpha
chr17_+_7743233 0.202 NM_001080424
KDM6B
lysine (K)-specific demethylase 6B
chr9_-_131534186 0.201 NM_006336
ZER1
zer-1 homolog (C. elegans)
chr10_+_76586299 0.199 NM_012330
KAT6B
K(lysine) acetyltransferase 6B
chr2_+_20646831 0.197 NM_004040
RHOB
ras homolog gene family, member B
chr11_-_46142955 0.196 NM_001101802
NM_016621
PHF21A

PHD finger protein 21A

chr17_+_18163836 0.192 NM_001144900
NM_139162
SMCR7

Smith-Magenis syndrome chromosome region, candidate 7

chr9_-_33264458 0.192 NM_001172415
NM_004323
BAG1

BCL2-associated athanogene

chr16_-_12897693 0.190 NM_001099455
NM_018340
CPPED1

calcineurin-like phosphoesterase domain containing 1

chr5_+_121647773 0.190 NM_001242935
NM_005460
SNCAIP

synuclein, alpha interacting protein

chr20_-_47894591 0.188 NM_021035
ZNFX1
zinc finger, NFX1-type containing 1
chr22_+_37415701 0.188 NM_001013436
NM_001130517
NM_021126
MPST


mercaptopyruvate sulfurtransferase


chr2_+_109204745 0.188 NM_004987
LIMS1
LIM and senescent cell antigen-like domains 1
chr19_-_1650246 0.186 NM_001136139
TCF3
transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)
chr4_+_87856152 0.185 NM_001166693
AFF1
AF4/FMR2 family, member 1
chr1_+_26438267 0.185 NM_001243533
NM_152835
PDIK1L

PDLIM1 interacting kinase 1 like

chr13_-_67804432 0.184 NM_020403
NM_203487
PCDH9

protocadherin 9

chrX_-_50557019 0.183 NM_020717
SHROOM4
shroom family member 4
chr8_+_123793894 0.179 NM_014943
ZHX2
zinc fingers and homeoboxes 2
chr7_-_72936592 0.178 NM_032408
BAZ1B
bromodomain adjacent to zinc finger domain, 1B
chr16_+_67876211 0.177 NM_020457
THAP11
THAP domain containing 11
chr11_-_61584451 0.176 NM_013402
FADS1
fatty acid desaturase 1
chr17_-_79881304 0.175 NM_032711
MAFG
v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)
chr6_+_20402040 0.175 NM_001949
E2F3
E2F transcription factor 3
chr5_-_150537335 0.173 NM_001155
ANXA6
annexin A6
chr5_-_150521200 0.173 NM_001193544
ANXA6
annexin A6
chr11_-_67980699 0.172 NM_016028
NM_017635
SUV420H1

suppressor of variegation 4-20 homolog 1 (Drosophila)

chr10_+_181410 0.170 NM_001202464
ZMYND11
zinc finger, MYND-type containing 11
chr17_-_39968450 0.166 NM_006455
LEPREL4
leprecan-like 4
chr3_+_183873253 0.166 NM_004423
DVL3
dishevelled, dsh homolog 3 (Drosophila)
chr18_+_55102777 0.165 NM_004852
ONECUT2
one cut homeobox 2
chr2_+_46926049 0.164 NM_014011
SOCS5
suppressor of cytokine signaling 5
chr22_-_29075708 0.163 NM_001145418
TTC28
tetratricopeptide repeat domain 28
chr8_-_41754244 0.163 NM_001142446
ANK1
ankyrin 1, erythrocytic
chr2_+_109223600 0.162 NM_001193482
LIMS1
LIM and senescent cell antigen-like domains 1
chr15_+_57511616 0.162 NM_207040
TCF12
transcription factor 12
chr14_-_21852424 0.161 NM_007192
SUPT16H
suppressor of Ty 16 homolog (S. cerevisiae)
chr5_+_179125796 0.160 NM_001024649
NM_001746
CANX

calnexin

chr2_+_219264477 0.159 NM_021198
NM_182642
CTDSP1

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1

chr3_+_23986735 0.159 NM_005126
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr20_-_52199635 0.159 NM_006526
ZNF217
zinc finger protein 217
chr7_-_131241321 0.158 NM_001018111
NM_005397
PODXL

podocalyxin-like

chr22_-_43355886 0.157 NM_001184971
PACSIN2
protein kinase C and casein kinase substrate in neurons 2
chr8_-_41522724 0.157 NM_001142445
NM_020478
NM_020480
ANK1


ankyrin 1, erythrocytic


chr2_+_46926323 0.156 NM_144949
SOCS5
suppressor of cytokine signaling 5
chr4_+_159131400 0.155 NM_018342
TMEM144
transmembrane protein 144
chr15_+_52311408 0.151 NM_002748
MAPK6
mitogen-activated protein kinase 6

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.