Motif ID: GFI1B.p2

Z-value: 1.165


Transcription factors associated with GFI1B.p2:

Gene SymbolEntrez IDGene Name
GFI1B 8328 growth factor independent 1B transcription repressor

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
GFI1Bchr9_+_135854097-0.581.8e-02Click!


Activity profile for motif GFI1B.p2.

activity profile for motif GFI1B.p2


Sorted Z-values histogram for motif GFI1B.p2

Sorted Z-values for motif GFI1B.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GFI1B.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_28124915 5.103 NM_002820
NM_198965
 PTHLH

parathyroid hormone-like hormone

chr7_-_27205148 3.128 NM_152739
 HOXA9
homeobox A9
chr7_-_27205123 3.101 HOXA9
homeobox A9
chr6_+_12290528 2.451 NM_001168319
NM_001955
 EDN1

endothelin 1

chr10_-_91011516 2.040 LIPA
lipase A, lysosomal acid, cholesterol esterase
chr21_-_27512668 2.040 NM_001136016
 APP
amyloid beta (A4) precursor protein
chr2_-_113542970 1.953 NM_000575
 IL1A
interleukin 1, alpha
chr17_+_70117168 1.719 SOX9
SRY (sex determining region Y)-box 9
chr10_-_91011562 1.687 LIPA
lipase A, lysosomal acid, cholesterol esterase
chr17_-_56494930 1.576 NM_017763
 RNF43
ring finger protein 43
chr5_+_102201526 1.545 NM_000919
NM_001177306
NM_138766
NM_138821
NM_138822
 PAM




peptidylglycine alpha-amidating monooxygenase




chr4_-_40936640 1.499 APBB2
amyloid beta (A4) precursor protein-binding, family B, member 2
chr5_+_66124603 1.436 NM_015183
 MAST4
microtubule associated serine/threonine kinase family member 4
chr6_-_134498973 1.420 NM_001143677
 SGK1
serum/glucocorticoid regulated kinase 1
chr1_+_101702304 1.345 NM_001400
 S1PR1
sphingosine-1-phosphate receptor 1
chr2_-_165424993 1.345 GRB14
growth factor receptor-bound protein 14
chr17_+_70117177 1.275 SOX9
SRY (sex determining region Y)-box 9
chr1_+_27189628 1.274 NM_006142
 SFN
stratifin
chr7_-_56101830 1.272 PSPH
phosphoserine phosphatase
chr2_-_113594325 1.252 NM_000576
 IL1B
interleukin 1, beta

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 25 entries
Enrichment   P-value GO Accession GO Term
496.06 2.11e-03 GO:0010193 response to ozone
372.06 4.22e-03 GO:0033591 response to L-ascorbic acid
186.06 1.96e-02 GO:0032331 negative regulation of chondrocyte differentiation
165.39 2.52e-02 GO:0051482 elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger
135.33 3.85e-02 GO:0032874 positive regulation of stress-activated MAPK cascade
97.10 1.37e-03 GO:0045840 positive regulation of mitosis
97.10 1.37e-03 GO:0051785 positive regulation of nuclear division
54.50 8.13e-03 GO:0060560 developmental growth involved in morphogenesis
42.57 7.09e-04 GO:0045787 positive regulation of cell cycle
32.41 3.91e-02 GO:0048871 multicellular organismal homeostasis
31.06 4.44e-02 GO:0007088 regulation of mitosis
31.06 4.44e-02 GO:0051783 regulation of nuclear division
17.46 2.46e-02 GO:0006874 cellular calcium ion homeostasis
17.06 2.69e-02 GO:0072503 cellular divalent inorganic cation homeostasis
16.87 2.82e-02 GO:0055074 calcium ion homeostasis
16.41 3.14e-02 GO:0072507 divalent inorganic cation homeostasis
16.37 3.25e-03 GO:0007346 regulation of mitotic cell cycle
12.80 1.08e-02 GO:0060429 epithelium development
7.77 4.35e-03 GO:0031328 positive regulation of cellular biosynthetic process
7.64 4.89e-03 GO:0009891 positive regulation of biosynthetic process

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
Enrichment   P-value GO Accession GO Term
212.63 1.37e-03 GO:0005149 interleukin-1 receptor binding