Motif ID: GTF2A1,2.p2

Z-value: 1.577


Transcription factors associated with GTF2A1,2.p2:

Gene SymbolEntrez IDGene Name
GTF2A1 2957 general transcription factor IIA, 1, 19/37kDa
GTF2A2 2958 general transcription factor IIA, 2, 12kDa

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
GTF2A2chr15_-_59949536-0.421.0e-01Click!
GTF2A1chr14_-_81687574-0.136.3e-01Click!


Activity profile for motif GTF2A1,2.p2.

activity profile for motif GTF2A1,2.p2


Sorted Z-values histogram for motif GTF2A1,2.p2

Sorted Z-values for motif GTF2A1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GTF2A1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_145878775 3.143 PLOD2
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr7_+_100770378 3.131 NM_000602
NM_001165413
 SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

chr12_+_53491417 2.892 NM_002178
 IGFBP6
insulin-like growth factor binding protein 6
chr3_-_145878936 2.803 PLOD2
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr19_+_41725098 2.656 NM_001699
NM_021913
 AXL

AXL receptor tyrosine kinase

chr21_+_42540054 2.387 BACE2
beta-site APP-cleaving enzyme 2
chr12_+_53491448 2.371 IGFBP6
insulin-like growth factor binding protein 6
chr21_+_42540092 2.341 BACE2
beta-site APP-cleaving enzyme 2
chr21_-_28217692 2.295 NM_006988
 ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr1_-_57045129 2.254 PPAP2B
phosphatidic acid phosphatase type 2B
chr12_+_13349601 2.235 NM_001423
 EMP1
epithelial membrane protein 1
chr1_-_57045214 2.220 PPAP2B
phosphatidic acid phosphatase type 2B
chr1_-_57045235 2.189 NM_003713
 PPAP2B
phosphatidic acid phosphatase type 2B
chrX_-_3264680 2.185 NM_015419
 MXRA5
matrix-remodelling associated 5
chr3_+_62304667 2.136 C3orf14
chromosome 3 open reading frame 14
chr1_-_57044980 2.130 PPAP2B
phosphatidic acid phosphatase type 2B
chr3_-_145879222 2.103 NM_000935
NM_182943
 PLOD2

procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2

chr15_+_81071708 2.081 NM_018689
 KIAA1199
KIAA1199
chr11_-_111782447 2.070 NM_001885
 CRYAB
crystallin, alpha B
chr21_+_42539727 2.041 NM_012105
NM_138991
NM_138992
 BACE2


beta-site APP-cleaving enzyme 2



Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 13 of 13 entries
Enrichment   P-value GO Accession GO Term
147.95 2.98e-02 GO:0010757 negative regulation of plasminogen activation
37.00 3.33e-02 GO:0010812 negative regulation of cell-substrate adhesion
30.62 3.95e-03 GO:0045861 negative regulation of proteolysis
21.35 1.66e-03 GO:0010810 regulation of cell-substrate adhesion
18.90 2.80e-02 GO:0061041 regulation of wound healing
13.55 1.58e-02 GO:0040013 negative regulation of locomotion
9.14 2.29e-02 GO:0001525 angiogenesis
9.01 2.47e-02 GO:0030155 regulation of cell adhesion
7.67 4.07e-03 GO:0001568 blood vessel development
7.15 6.81e-03 GO:0001944 vasculature development
6.10 2.10e-03 GO:0048646 anatomical structure formation involved in morphogenesis
5.06 2.93e-02 GO:0072358 cardiovascular system development
5.06 2.93e-02 GO:0072359 circulatory system development

Gene overrepresentation in compartment category:

Showing 1 to 4 of 4 entries
Enrichment   P-value GO Accession GO Term
6.01 3.75e-03 GO:0031012 extracellular matrix
4.02 2.33e-03 GO:0005615 extracellular space
3.99 2.01e-04 GO:0044421 extracellular region part
2.97 5.50e-04 GO:0005576 extracellular region

Nothing significant found in function category.