Motif ID: GTF2I.p2

Z-value: 1.493


Transcription factors associated with GTF2I.p2:

Gene SymbolEntrez IDGene Name
GTF2I 2969 general transcription factor II, i

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
GTF2Ichr7_+_740720550.504.9e-02Click!


Activity profile for motif GTF2I.p2.

activity profile for motif GTF2I.p2


Sorted Z-values histogram for motif GTF2I.p2

Sorted Z-values for motif GTF2I.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GTF2I.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrY_+_148060 5.210 NM_018390
PLCXD1
phosphatidylinositol-specific phospholipase C, X domain containing 1
chrX_+_198060 5.145 NM_018390
PLCXD1
phosphatidylinositol-specific phospholipase C, X domain containing 1
chr20_-_22564893 4.566 FOXA2
forkhead box A2
chr19_+_45452427 3.756 APOC2
apolipoprotein C-II
chr11_-_2159472 2.735 IGF2
insulin-like growth factor 2 (somatomedin A)
chr1_-_20812727 2.504 NM_018584
CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr20_-_22565050 2.363 NM_021784
FOXA2
forkhead box A2
chr12_-_115121939 2.315 NM_005996
NM_016569
TBX3

T-box 3

chr14_-_54423448 2.228 NM_001202
NM_130850
BMP4

bone morphogenetic protein 4

chr10_+_114709963 2.074 NM_001146274
NM_001146283
NM_001146284
NM_001146285
NM_001146286
NM_001198525
NM_001198526
NM_001198527
NM_001198528
NM_001198529
NM_001198530
NM_001198531
NM_030756
TCF7L2












transcription factor 7-like 2 (T-cell specific, HMG-box)












chr11_-_2160199 2.072 NM_000612
IGF2
insulin-like growth factor 2 (somatomedin A)
chr8_+_97506141 2.050 SDC2
syndecan 2
chr11_-_2159925 2.049 IGF2
insulin-like growth factor 2 (somatomedin A)
chr1_-_92351476 2.036 TGFBR3
transforming growth factor, beta receptor III
chr2_-_39664430 2.032 MAP4K3
mitogen-activated protein kinase kinase kinase kinase 3
chr16_-_29910340 1.961 NM_001114099
NM_001114100
NM_001243332
NM_001243333
NM_012410
NM_201575
SEZ6L2





seizure related 6 homolog (mouse)-like 2





chr2_+_128175989 1.904 NM_000312
PROC
protein C (inactivator of coagulation factors Va and VIIIa)
chr2_+_128176019 1.898 PROC
protein C (inactivator of coagulation factors Va and VIIIa)
chr5_+_92918924 1.844 NM_005654
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr5_+_92920592 1.747 NR2F1
NR2F2
nuclear receptor subfamily 2, group F, member 1
nuclear receptor subfamily 2, group F, member 2
chr19_+_50016435 1.652 NM_004107
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr11_-_2159784 1.651 IGF2
insulin-like growth factor 2 (somatomedin A)
chr14_+_32546445 1.590 NM_001030055
NM_001173
ARHGAP5

Rho GTPase activating protein 5

chr2_+_62932786 1.581 NM_001142616
NM_015252
EHBP1

EH domain binding protein 1

chr2_-_39664291 1.571 MAP4K3
mitogen-activated protein kinase kinase kinase kinase 3
chr2_-_227663454 1.544 NM_005544
IRS1
insulin receptor substrate 1
chr8_+_97506071 1.534 SDC2
syndecan 2
chr19_-_6720585 1.529 NM_000064
C3
complement component 3
chr16_-_73092533 1.521 NM_001164766
ZFHX3
zinc finger homeobox 3
chr8_+_97506020 1.503 SDC2
syndecan 2
chr17_-_36904545 1.485 NM_007144
PCGF2
polycomb group ring finger 2
chr2_-_218843541 1.476 TNS1
tensin 1
chr1_-_92351613 1.470 NM_001195683
NM_003243
TGFBR3

transforming growth factor, beta receptor III

chr16_+_69599869 1.456 NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr16_+_69599868 1.440 NM_001113178
NM_006599
NM_138713
NM_138714
NM_173214
NM_173215
NFAT5





nuclear factor of activated T-cells 5, tonicity-responsive





chr8_+_97505895 1.430 SDC2
syndecan 2
chr7_+_29234111 1.371 NM_004067
CHN2
chimerin (chimaerin) 2
chrX_-_128657453 1.355 NM_003069
NM_139035
SMARCA1

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1

chr7_-_150038689 1.351 NM_002889
RARRES2
retinoic acid receptor responder (tazarotene induced) 2
chr3_-_50349811 1.345 NM_153281
HYAL1
hyaluronoglucosaminidase 1
chr14_+_21538339 1.333 NM_018071
ARHGEF40
Rho guanine nucleotide exchange factor (GEF) 40
chrX_-_128657440 1.313 SMARCA1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chrX_-_130423387 1.304 NM_001170961
NM_001170962
NM_001555
NM_205833
IGSF1



immunoglobulin superfamily, member 1



chrX_-_20284910 1.299 RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr4_-_1166959 1.286 NM_001128325
SPON2
spondin 2, extracellular matrix protein
chr6_+_37137882 1.266 NM_001243186
NM_002648
PIM1

pim-1 oncogene

chr3_+_187871473 1.237 NM_001167672
LPP
LIM domain containing preferred translocation partner in lipoma
chr19_+_35629727 1.220 NM_021902
FXYD1
FXYD domain containing ion transport regulator 1
chrX_-_130423199 1.188 IGSF1
immunoglobulin superfamily, member 1
chr22_-_36236330 1.173 RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chrX_-_128657381 1.169 SMARCA1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr14_-_54421269 1.137 NM_130851
BMP4
bone morphogenetic protein 4
chr5_+_135364583 1.128 NM_000358
TGFBI
transforming growth factor, beta-induced, 68kDa
chr11_-_86666211 1.120 NM_012193
FZD4
frizzled family receptor 4
chrX_-_20285141 1.119 RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr19_+_45417920 1.081 NM_001645
APOC1
apolipoprotein C-I
chr8_+_97505876 1.078 NM_002998
SDC2
syndecan 2
chr3_-_185542807 1.076 NM_001007225
NM_006548
IGF2BP2

insulin-like growth factor 2 mRNA binding protein 2

chr21_+_40177754 1.075 ETS2
v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)
chr2_-_169103886 1.062 NM_013233
STK39
serine threonine kinase 39
chr2_-_21266809 1.061 APOB
apolipoprotein B (including Ag(x) antigen)
chr13_+_98795710 1.061 FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr2_+_54683276 1.052 NM_003128
SPTBN1
spectrin, beta, non-erythrocytic 1
chr15_-_37392322 1.031 MEIS2
Meis homeobox 2
chr16_-_30934437 1.029 FBXL19-AS1
FBXL19 antisense RNA 1 (non-protein coding)
chr14_+_101193190 1.029 NM_003836
DLK1
delta-like 1 homolog (Drosophila)
chr18_+_55711890 1.028 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr2_-_61697899 1.024 USP34
ubiquitin specific peptidase 34
chr5_+_36876838 1.014 NM_015384
NM_133433
NIPBL

Nipped-B homolog (Drosophila)

chr14_+_101193275 1.014 DLK1
delta-like 1 homolog (Drosophila)
chr1_+_214161279 1.009 PROX1
prospero homeobox 1
chr2_-_39664129 1.007 NM_003618
MAP4K3
mitogen-activated protein kinase kinase kinase kinase 3
chr17_+_45727303 1.000 KPNB1
karyopherin (importin) beta 1
chr17_+_45727558 0.987 KPNB1
karyopherin (importin) beta 1
chr2_+_46926049 0.984 NM_014011
SOCS5
suppressor of cytokine signaling 5
chr16_+_69600110 0.980 NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr14_+_23775970 0.973 NM_001199864
NM_004050
NM_001199839
BCL2L2-PABPN1
BCL2L2

BCL2L2-PABPN1 readthrough
BCL2-like 2

chr17_-_7155258 0.972 NM_015343
CTDNEP1
CTD nuclear envelope phosphatase 1
chr2_-_200322699 0.952 NM_001172509
SATB2
SATB homeobox 2
chr16_+_85645014 0.951 NM_001134473
KIAA0182
KIAA0182
chr3_+_37903643 0.947 NM_001008392
NM_005808
CTDSPL

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like

chr15_-_37392358 0.945 NM_170674
NM_170675
NM_170676
NM_170677
MEIS2



Meis homeobox 2



chr14_+_68086633 0.944 ARG2
arginase, type II
chr19_-_18717577 0.941 CRLF1
cytokine receptor-like factor 1
chr6_-_32143886 0.939 AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr17_+_53342356 0.939 HLF
hepatic leukemia factor
chr2_-_167232464 0.938 NM_002977
SCN9A
sodium channel, voltage-gated, type IX, alpha subunit
chr3_+_167453431 0.933 NM_001122752
NM_005025
SERPINI1

serpin peptidase inhibitor, clade I (neuroserpin), member 1

chr8_+_123793988 0.927 ZHX2
zinc fingers and homeoboxes 2
chr5_+_36876899 0.922 NIPBL
Nipped-B homolog (Drosophila)
chr22_-_36236264 0.908 RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr2_-_174828775 0.908 NM_001017371
SP3
Sp3 transcription factor
chr14_-_89883306 0.902 NM_005197
FOXN3
forkhead box N3
chr2_+_46926323 0.900 NM_144949
SOCS5
suppressor of cytokine signaling 5
chr21_+_40177847 0.899 NM_005239
ETS2
v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)
chr2_-_21266893 0.898 APOB
apolipoprotein B (including Ag(x) antigen)
chr14_+_101193313 0.896 DLK1
delta-like 1 homolog (Drosophila)
chr4_-_16900348 0.885 NM_001130834
NM_001290
LDB2

LIM domain binding 2

chr4_-_1166547 0.881 NM_012445
SPON2
spondin 2, extracellular matrix protein
chr6_-_32143795 0.875 AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr2_-_21266915 0.870 NM_000384
APOB
apolipoprotein B (including Ag(x) antigen)
chr22_-_36236421 0.865 NM_001031695
NM_001082576
NM_001082577
NM_014309
RBFOX2



RNA binding protein, fox-1 homolog (C. elegans) 2



chr16_-_10674443 0.855 NM_001424
EMP2
epithelial membrane protein 2
chr14_-_38064440 0.844 NM_004496
FOXA1
forkhead box A1
chr2_+_187454724 0.842 NM_001145000
NM_002210
ITGAV

integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)

chrX_+_49644469 0.841 NM_001145073
USP27X
ubiquitin specific peptidase 27, X-linked
chr8_+_30241943 0.824 NM_001008710
NM_001008711
NM_001008712
NM_006867
RBPMS



RNA binding protein with multiple splicing



chr12_+_53845884 0.824 NM_001098620
NM_001128911
NM_001128912
NM_001128913
NM_001128914
NM_005016
NM_031989
PCBP2






poly(rC) binding protein 2






chr14_-_94856926 0.821 NM_001002235
NM_001002236
NM_001127700
NM_001127701
NM_001127702
NM_001127703
NM_001127704
NM_001127705
NM_001127706
NM_001127707
SERPINA1









serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1









chr2_-_227664330 0.813 IRS1
insulin receptor substrate 1
chr17_+_53342320 0.808 NM_002126
HLF
hepatic leukemia factor
chr19_+_50016490 0.804 FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr7_+_94285620 0.802 NM_001040152
NM_001184961
NM_001184962
NM_015068
PEG10



paternally expressed 10



chr1_+_214161859 0.796 NM_002763
PROX1
prospero homeobox 1
chr3_-_32022734 0.796 OSBPL10
oxysterol binding protein-like 10
chr4_+_1795004 0.795 NM_000142
NM_001163213
NM_022965
FGFR3


fibroblast growth factor receptor 3


chr16_-_52580805 0.791 NM_001080430
TOX3
TOX high mobility group box family member 3
chr7_-_103629962 0.787 NM_005045
NM_173054
RELN

reelin

chr3_-_32023237 0.784 NM_001174060
NM_017784
OSBPL10

oxysterol binding protein-like 10

chr1_+_169075869 0.781 NM_001677
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr22_+_45898690 0.778 NM_001996
NM_006485
NM_006486
NM_006487
FBLN1



fibulin 1



chr1_+_205473768 0.773 CDK18
cyclin-dependent kinase 18
chr5_+_52776408 0.769 FST
follistatin
chr17_+_27370155 0.768 PIPOX
pipecolic acid oxidase
chr11_-_70672644 0.768 SHANK2
SH3 and multiple ankyrin repeat domains 2
chr6_-_32157511 0.768 NM_002586
PBX2
pre-B-cell leukemia homeobox 2
chr12_+_56473944 0.762 ERBB3
v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
chr10_+_114710785 0.757 TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr7_+_138144847 0.752 NM_003852
NM_015905
TRIM24

tripartite motif containing 24

chrX_+_107683015 0.748 NM_000495
NM_033380
COL4A5

collagen, type IV, alpha 5

chrX_+_152954965 0.747 NM_001142806
SLC6A8
solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chr20_+_8112762 0.745 NM_015192
NM_182734
PLCB1

phospholipase C, beta 1 (phosphoinositide-specific)

chr19_-_18717631 0.743 NM_004750
CRLF1
cytokine receptor-like factor 1
chr2_-_136743189 0.740 NM_001349
DARS
aspartyl-tRNA synthetase
chr6_-_134497069 0.737 NM_001143678
SGK1
serum/glucocorticoid regulated kinase 1
chr19_-_48894755 0.732 NM_006801
KDELR1
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
chr5_+_52776479 0.730 FST
follistatin
chr7_+_45927958 0.730 NM_000596
IGFBP1
insulin-like growth factor binding protein 1
chr17_+_27369917 0.729 NM_016518
PIPOX
pipecolic acid oxidase
chr5_+_150400132 0.729 GPX3
glutathione peroxidase 3 (plasma)
chr7_+_94138991 0.723 NM_022900
CASD1
CAS1 domain containing 1
chr7_+_73868397 0.720 GTF2IRD1
GTF2I repeat domain containing 1
chr20_-_3154169 0.716 ProSAPiP1
ProSAPiP1 protein
chr3_+_9439290 0.711 NM_001080517
SETD5
SET domain containing 5
chr20_+_44035203 0.704 NM_001048223
NM_001048224
DBNDD2

dysbindin (dystrobrevin binding protein 1) domain containing 2

chr12_+_3068442 0.704 NM_003213
NM_201441
NM_201443
TEAD4


TEA domain family member 4


chr1_+_205473683 0.703 NM_002596
NM_212502
NM_212503
CDK18


cyclin-dependent kinase 18


chr7_+_73868111 0.703 NM_001199207
NM_005685
NM_016328
GTF2IRD1


GTF2I repeat domain containing 1


chr5_-_172756505 0.703 NM_003714
STC2
stanniocalcin 2
chr13_-_96296919 0.702 NM_014934
NM_198968
DZIP1

DAZ interacting protein 1

chr17_-_7082654 0.702 NM_001197216
NM_001671
ASGR1

asialoglycoprotein receptor 1

chr8_+_123794043 0.699 ZHX2
zinc fingers and homeoboxes 2
chr2_+_219283809 0.699 NM_007127
VIL1
villin 1
chr1_+_204042191 0.693 NM_005686
SOX13
SRY (sex determining region Y)-box 13
chr17_+_45726838 0.691 KPNB1
karyopherin (importin) beta 1
chr17_+_70117177 0.690 SOX9
SRY (sex determining region Y)-box 9
chr13_+_98795468 0.685 FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr19_+_50016500 0.683 FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr19_+_56652529 0.681 NM_001253792
NM_018337
ZNF444

zinc finger protein 444

chr13_+_98795410 0.679 NM_001001715
NM_005766
FARP1

FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)

chr11_+_73359734 0.679 NM_001130036
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr7_-_27170351 0.678 NM_002141
HOXA4
homeobox A4
chr6_-_134496833 0.677 SGK1
serum/glucocorticoid regulated kinase 1
chr17_-_41623246 0.677 NM_001986
ETV4
ets variant 4
chr6_+_31868775 0.673 NM_001178063
C2
complement component 2
chr19_-_48894615 0.665 KDELR1
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
chr17_-_53499055 0.665 NM_012329
MMD
monocyte to macrophage differentiation-associated
chr3_-_185542744 0.663 IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr11_-_35441099 0.662 NM_004171
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr2_-_174829108 0.661 SP3
Sp3 transcription factor
chr20_+_306205 0.659 NM_006943
SOX12
SRY (sex determining region Y)-box 12
chr2_-_136743076 0.654 DARS
aspartyl-tRNA synthetase
chr12_-_81331487 0.652 NM_004664
LIN7A
lin-7 homolog A (C. elegans)
chr18_+_32621299 0.650 NM_014268
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr8_-_134584012 0.647 NM_003033
NM_173344
ST3GAL1

ST3 beta-galactoside alpha-2,3-sialyltransferase 1

chr8_+_123793894 0.646 NM_014943
ZHX2
zinc fingers and homeoboxes 2
chr10_+_21823093 0.642 NM_001195627
NM_001195628
NM_001195630
NM_004641
MLLT10



myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10



chr6_+_1390068 0.639 NM_001452
FOXF2
forkhead box F2
chr6_+_33378772 0.633 NM_002636
NM_024165
PHF1

PHD finger protein 1

chr19_+_35521591 0.633 NM_001037
NM_199037
SCN1B

sodium channel, voltage-gated, type I, beta

chr1_-_227505796 0.633 NM_003607
NM_014826
CDC42BPA

CDC42 binding protein kinase alpha (DMPK-like)

chr17_+_45727274 0.630 NM_002265
KPNB1
karyopherin (importin) beta 1
chr11_+_57365026 0.629 NM_000062
SERPING1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr18_+_55711388 0.629 NM_001144967
NM_001243960
NM_015277
NEDD4L


neural precursor cell expressed, developmentally down-regulated 4-like


chr6_-_32143899 0.627 NM_006411
AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr2_+_159313466 0.621 NM_001005476
NM_003628
PKP4

plakophilin 4

chr3_-_9439122 0.620 LOC440944
uncharacterized LOC440944
chr4_-_80994183 0.618


chr6_-_32143676 0.618 AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chrX_+_54834775 0.618 NM_014599
MAGED2
melanoma antigen family D, 2
chr4_-_39528921 0.616 UGDH
UDP-glucose 6-dehydrogenase
chr11_-_35440514 0.613 SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr1_+_116916488 0.610 NM_001160233
ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr20_+_34742656 0.608 NM_012156
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr17_+_40834571 0.607 NM_003632
CNTNAP1
contactin associated protein 1
chr10_+_111969988 0.607 NM_001008541
MXI1
MAX interactor 1
chr20_+_44034632 0.607 NM_001197139
NM_001048221
NM_001048222
NM_001197140
NM_018478
DBNDD2




dysbindin (dystrobrevin binding protein 1) domain containing 2




chr12_-_7261788 0.604 NM_016546
C1RL
complement component 1, r subcomponent-like
chr6_+_31623688 0.602 APOM
apolipoprotein M
chr17_-_7154994 0.600 NM_001143775
CTDNEP1
CTD nuclear envelope phosphatase 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
5.90 1.06e-04 GO:0031327 negative regulation of cellular biosynthetic process
5.77 1.36e-04 GO:0009890 negative regulation of biosynthetic process
8.41 1.43e-04 GO:0043009 chordate embryonic development
3.15 1.61e-04 GO:0048523 negative regulation of cellular process
8.29 1.62e-04 GO:0009792 embryo development ending in birth or egg hatching
3.01 1.72e-04 GO:0048519 negative regulation of biological process
7.79 2.89e-04 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
5.98 3.02e-04 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
5.93 3.29e-04 GO:0051172 negative regulation of nitrogen compound metabolic process
5.70 5.02e-04 GO:0010558 negative regulation of macromolecule biosynthetic process
6.36 5.36e-04 GO:0045892 negative regulation of transcription, DNA-dependent
1.80 5.56e-04 GO:0050794 regulation of cellular process
6.21 6.75e-04 GO:0051253 negative regulation of RNA metabolic process
1.74 8.51e-04 GO:0050789 regulation of biological process
121.63 8.71e-04 GO:0045662 negative regulation of myoblast differentiation
6.87 9.13e-04 GO:0032583 regulation of gene-specific transcription
4.35 1.32e-03 GO:0009892 negative regulation of metabolic process
3.54 1.39e-03 GO:0009653 anatomical structure morphogenesis
7.59 1.45e-03 GO:0007420 brain development
5.71 1.54e-03 GO:0010629 negative regulation of gene expression
1.66 1.65e-03 GO:0065007 biological regulation
5.51 2.17e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.69 2.62e-03 GO:0009889 regulation of biosynthetic process
6.08 2.73e-03 GO:0007417 central nervous system development
4.39 2.98e-03 GO:0031324 negative regulation of cellular metabolic process
33.57 3.70e-03 GO:0051153 regulation of striated muscle cell differentiation
2.52 4.10e-03 GO:0048731 system development
2.00 4.61e-03 GO:0032501 multicellular organismal process
5.09 4.71e-03 GO:0009790 embryo development
17.90 5.41e-03 GO:0055123 digestive system development
7.47 6.41e-03 GO:0001501 skeletal system development
2.37 6.66e-03 GO:0048856 anatomical structure development
4.01 8.03e-03 GO:0032879 regulation of localization
2.59 8.69e-03 GO:0031326 regulation of cellular biosynthetic process
60.83 9.42e-03 GO:0045661 regulation of myoblast differentiation
60.83 9.42e-03 GO:0051148 negative regulation of muscle cell differentiation
243.25 1.13e-02 GO:0060696 regulation of phospholipid catabolic process
243.25 1.13e-02 GO:0060838 lymphatic endothelial cell fate commitment
243.25 1.13e-02 GO:0060839 endothelial cell fate commitment
243.25 1.13e-02 GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment
243.25 1.13e-02 GO:0072148 epithelial cell fate commitment
4.06 1.68e-02 GO:0010605 negative regulation of macromolecule metabolic process
5.55 1.85e-02 GO:0072358 cardiovascular system development
5.55 1.85e-02 GO:0072359 circulatory system development
2.22 2.19e-02 GO:0007275 multicellular organismal development
2.21 2.32e-02 GO:0080090 regulation of primary metabolic process
2.62 2.37e-02 GO:2000112 regulation of cellular macromolecule biosynthetic process
45.63 2.37e-02 GO:0048844 artery morphogenesis
3.17 2.52e-02 GO:0007399 nervous system development
7.39 2.64e-02 GO:0061061 muscle structure development
7.36 2.71e-02 GO:0001568 blood vessel development
9.31 2.74e-02 GO:0032582 negative regulation of gene-specific transcription
3.82 3.01e-02 GO:0006357 regulation of transcription from RNA polymerase II promoter
162.17 3.37e-02 GO:0035117 embryonic arm morphogenesis
162.17 3.37e-02 GO:0035140 arm morphogenesis
162.17 3.37e-02 GO:0060836 lymphatic endothelial cell differentiation
40.56 3.43e-02 GO:0060840 artery development
2.37 3.50e-02 GO:0048518 positive regulation of biological process
2.10 3.58e-02 GO:0032502 developmental process
2.55 3.62e-02 GO:0010556 regulation of macromolecule biosynthetic process
38.42 4.07e-02 GO:0034381 plasma lipoprotein particle clearance
6.86 4.25e-02 GO:0001944 vasculature development
36.50 4.77e-02 GO:0003158 endothelium development
6.70 4.94e-02 GO:0051130 positive regulation of cellular component organization

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
66.35 8.05e-04 GO:0042627 chylomicron
3.80 1.65e-03 GO:0044421 extracellular region part
40.56 3.90e-03 GO:0034361 very-low-density lipoprotein particle
40.56 3.90e-03 GO:0034385 triglyceride-rich lipoprotein particle
4.04 4.58e-03 GO:0005615 extracellular space
121.63 7.63e-03 GO:0034363 intermediate-density lipoprotein particle
22.82 2.28e-02 GO:0032994 protein-lipid complex
22.82 2.28e-02 GO:0034358 plasma lipoprotein particle

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
6.47 2.57e-04 GO:0019904 protein domain specific binding
7.87 2.90e-03 GO:0003702 RNA polymerase II transcription factor activity
3.75 6.03e-03 GO:0030528 transcription regulator activity
3.51 2.36e-02 GO:0001071 nucleic acid binding transcription factor activity
3.51 2.36e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
12.82 2.85e-02 GO:0003704 specific RNA polymerase II transcription factor activity
4.09 3.17e-02 GO:0043565 sequence-specific DNA binding