Motif ID: GUGCAAA

Z-value: 2.917


Mature miRNA associated with seed GUGCAAA:

NamemiRBase Accession
hsa-miR-19a MIMAT0000073
hsa-miR-19b MIMAT0000074



Activity profile for motif GUGCAAA.

activity profile for motif GUGCAAA


Sorted Z-values histogram for motif GUGCAAA

Sorted Z-values for motif GUGCAAA



Network of associatons between targets according to the STRING database.



First level regulatory network of GUGCAAA

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_1748285 10.393 NM_012293
PXDN
peroxidasin homolog (Drosophila)
chr13_-_107187312 8.083 NM_004093
EFNB2
ephrin-B2
chr7_+_134464161 7.866 NM_004342
NM_033138
NM_033157
CALD1


caldesmon 1


chr6_+_121756744 7.700 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr6_-_132272311 7.148 NM_001901
CTGF
connective tissue growth factor
chr2_+_173292306 7.108 NM_000210
NM_001079818
ITGA6

integrin, alpha 6

chr20_+_19867075 6.869 NM_001242581
RIN2
Ras and Rab interactor 2
chr15_+_39873276 6.646 NM_003246
THBS1
thrombospondin 1
chr4_+_38869346 6.622 NM_138389
FAM114A1
family with sequence similarity 114, member A1
chr11_+_69455837 6.619 NM_053056
CCND1
cyclin D1
chr20_+_19870209 6.606 NM_018993
RIN2
Ras and Rab interactor 2
chr7_+_134576150 6.361 NM_033139
NM_033140
CALD1

caldesmon 1

chr11_-_12030882 6.164 NM_013253
DKK3
dickkopf 3 homolog (Xenopus laevis)
chr2_-_161350304 6.105 NM_002897
NM_016836
RBMS1

RNA binding motif, single stranded interacting protein 1

chr11_-_12030128 6.026 NM_001018057
DKK3
dickkopf 3 homolog (Xenopus laevis)
chr11_-_12030622 5.910 NM_015881
DKK3
dickkopf 3 homolog (Xenopus laevis)
chr3_-_98620452 5.638 NM_080927
DCBLD2
discoidin, CUB and LCCL domain containing 2
chr6_-_134639195 5.587 NM_001143676
SGK1
serum/glucocorticoid regulated kinase 1
chr6_-_134498973 5.480 NM_001143677
SGK1
serum/glucocorticoid regulated kinase 1
chr2_+_20646831 5.471 NM_004040
RHOB
ras homolog gene family, member B
chr3_+_30647901 5.440 NM_001024847
NM_003242
TGFBR2

transforming growth factor, beta receptor II (70/80kDa)

chr2_+_9346876 5.341 NM_001135191
NM_003887
ASAP2

ArfGAP with SH3 domain, ankyrin repeat and PH domain 2

chr6_-_134496006 5.302 NM_005627
SGK1
serum/glucocorticoid regulated kinase 1
chr20_-_56286540 5.249 NM_199171
PMEPA1
prostate transmembrane protein, androgen induced 1
chr12_+_78225068 5.101 NM_014903
NAV3
neuron navigator 3
chrX_-_10588458 5.074 NM_000381
NM_033289
MID1

midline 1 (Opitz/BBB syndrome)

chr2_-_20425166 5.059 NM_001006946
SDC1
syndecan 1
chr16_+_3070310 4.973 NM_016639
TNFRSF12A
tumor necrosis factor receptor superfamily, member 12A
chr1_-_95007139 4.927 NM_001178096
NM_001993
F3

coagulation factor III (thromboplastin, tissue factor)

chr6_-_134497069 4.864 NM_001143678
SGK1
serum/glucocorticoid regulated kinase 1
chr5_-_136834887 4.814 NM_004598
SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chrX_-_10645726 4.721 NM_001098624
MID1
midline 1 (Opitz/BBB syndrome)
chr9_-_107690526 4.629 NM_005502
ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
chrX_-_10544852 4.621 NM_001193277
MID1
midline 1 (Opitz/BBB syndrome)
chr7_-_27183225 4.607 NM_019102
HOXA5
homeobox A5
chr2_-_20424627 4.550 NM_002997
SDC1
syndecan 1
chr22_-_36236421 4.489 NM_001031695
NM_001082576
NM_001082577
NM_014309
RBFOX2



RNA binding protein, fox-1 homolog (C. elegans) 2



chrX_-_10851808 4.370 NM_033290
MID1
midline 1 (Opitz/BBB syndrome)
chr22_-_36424397 4.285 NM_001082578
NM_001082579
RBFOX2

RNA binding protein, fox-1 homolog (C. elegans) 2

chr20_-_56285576 4.233 NM_199169
NM_199170
PMEPA1

prostate transmembrane protein, androgen induced 1

chr20_-_56284945 4.130 NM_020182
PMEPA1
prostate transmembrane protein, androgen induced 1
chr5_-_73937248 3.995 NM_003633
ENC1
ectodermal-neural cortex 1 (with BTB-like domain)
chr9_-_14398981 3.882 NM_001190738
NFIB
nuclear factor I/B
chr1_+_82266081 3.815 NM_012302
LPHN2
latrophilin 2
chr8_+_104310660 3.722 NM_001164615
FZD6
frizzled family receptor 6
chr8_+_104311058 3.522 NM_001164616
NM_003506
FZD6

frizzled family receptor 6

chr8_-_67525426 3.506 NM_001080416
NM_001144755
MYBL1

LOC645895
v-myb myeloblastosis viral oncogene homolog (avian)-like 1

uncharacterized LOC645895
chr8_-_17555158 3.488 NM_020749
MTUS1
microtubule associated tumor suppressor 1
chr4_-_52904424 3.474 NM_000232
SGCB
sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
chr6_+_21593963 3.448 NM_003107
SOX4
SRY (sex determining region Y)-box 4
chr1_-_94147201 3.435 NM_003567
BCAR3
breast cancer anti-estrogen resistance 3
chr9_-_14314036 3.434 NM_001190737
NM_005596
NFIB

nuclear factor I/B

chr8_-_17658385 3.398 NM_001001924
NM_001001925
MTUS1

microtubule associated tumor suppressor 1

chr3_+_187943192 3.360 NM_001167671
LPP
LIM domain containing preferred translocation partner in lipoma
chr14_-_69446038 3.357 NM_001102
NM_001130004
NM_001130005
ACTN1


actinin, alpha 1


chr2_-_169103886 3.352 NM_013233
STK39
serine threonine kinase 39
chr4_+_85504056 3.279 NM_001263
CDS1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr11_+_69924407 3.225 NM_018043
ANO1
anoctamin 1, calcium activated chloride channel
chr4_+_166248816 3.152 NM_001017369
NM_006745
MSMO1

methylsterol monooxygenase 1

chr3_+_187871473 3.127 NM_001167672
LPP
LIM domain containing preferred translocation partner in lipoma
chr3_+_61547179 3.114 NM_002841
PTPRG
protein tyrosine phosphatase, receptor type, G
chr8_-_17580024 3.089 NM_001166393
MTUS1
microtubule associated tumor suppressor 1
chr2_-_86116016 3.001 NM_003896
ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr12_-_106533810 2.964 NM_014840
NUAK1
NUAK family, SNF1-like kinase, 1
chr8_-_17579729 2.946 NM_001001931
MTUS1
microtubule associated tumor suppressor 1
chrX_-_34675366 2.903 NM_031442
TMEM47
transmembrane protein 47
chr3_+_187930720 2.898 NM_005578
LPP
LIM domain containing preferred translocation partner in lipoma
chr9_+_115913227 2.889 NM_001860
SLC31A2
solute carrier family 31 (copper transporters), member 2
chr5_+_95997723 2.857 NM_001190442
CAST
calpastatin
chr7_-_27205148 2.840 NM_152739
HOXA9
homeobox A9
chr18_+_3453771 2.803 NM_173211
TGIF1
TGFB-induced factor homeobox 1
chr3_-_69062744 2.786 NM_173654
C3orf64
chromosome 3 open reading frame 64
chr5_+_95997871 2.766 NM_001042440
CAST
calpastatin
chr14_+_55034329 2.669 NM_001161576
NM_015589
SAMD4A

sterile alpha motif domain containing 4A

chr2_+_64681270 2.649 NM_014181
LGALSL
lectin, galactoside-binding-like
chr7_-_95064213 2.601 NM_000305
NM_001018161
PON2

paraoxonase 2

chr6_+_89790412 2.579 NM_006813
PNRC1
proline-rich nuclear receptor coactivator 1
chr5_+_96038492 2.569 NM_173060
CAST
calpastatin
chr12_+_79439432 2.567 NM_001135806
SYT1
synaptotagmin I
chr12_+_79258448 2.520 NM_005639
SYT1
synaptotagmin I
chr2_-_86094792 2.486 NM_001042437
ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr18_+_3447607 2.460 NM_173207
TGIF1
TGFB-induced factor homeobox 1
chr12_+_79257772 2.423 NM_001135805
SYT1
synaptotagmin I
chr6_-_167275657 2.365 NM_001006932
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr19_+_11200037 2.356 NM_000527
NM_001195798
NM_001195799
NM_001195800
NM_001195802
NM_001195803
LDLR





low density lipoprotein receptor





chr20_-_36156282 2.356 NM_001167820
NM_006698
BLCAP

bladder cancer associated protein

chr3_+_100211408 2.310 NM_018004
TMEM45A
transmembrane protein 45A
chr8_-_12990731 2.297 NM_006094
DLC1
deleted in liver cancer 1
chr5_+_52284903 2.294 NM_002203
ITGA2
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
chr18_+_3412071 2.287 NM_174886
TGIF1
TGFB-induced factor homeobox 1
chr18_+_8717368 2.274 NM_015210
CCDC165
coiled-coil domain containing 165
chr20_-_36156082 2.258 NM_001167822
NM_001167821
BLCAP

bladder cancer associated protein

chr8_-_12973752 2.233 NM_001164271
DLC1
deleted in liver cancer 1
chr10_-_79686279 2.232 NM_004747
DLG5
discs, large homolog 5 (Drosophila)
chr3_-_124774735 2.229 NM_020733
HEG1
HEG homolog 1 (zebrafish)
chr18_+_3451589 2.211 NM_170695
NM_173210
TGIF1

TGFB-induced factor homeobox 1

chr19_-_45909566 2.209 NM_001142502
PPP1R13L
protein phosphatase 1, regulatory subunit 13 like
chr5_-_1882764 2.174 NM_016358
IRX4
iroquois homeobox 4
chr15_-_73925658 2.164 NM_001161363
NM_001161364
NM_012428
NM_017455
NPTN



neuroplastin



chr18_+_3449972 2.157 NM_173209
NM_173208
NM_003244
TGIF1


TGFB-induced factor homeobox 1


chr7_-_111846384 2.154 NM_014705
DOCK4
dedicator of cytokinesis 4
chr2_+_203241044 2.124 NM_001204
BMPR2
bone morphogenetic protein receptor, type II (serine/threonine kinase)
chr1_+_160175114 2.069 NM_003768
PEA15
phosphoprotein enriched in astrocytes 15
chr19_-_45908288 1.954 NM_006663
PPP1R13L
protein phosphatase 1, regulatory subunit 13 like
chr6_-_167040700 1.882 NM_021135
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr22_-_28197469 1.872 NM_002430
MN1
meningioma (disrupted in balanced translocation) 1
chr5_-_55290601 1.871 NM_001190981
NM_002184
NM_175767
IL6ST


interleukin 6 signal transducer (gp130, oncostatin M receptor)


chr1_-_93426998 1.869 NM_001006605
NM_001252269
NM_001252270
NM_001252273
FAM69A



family with sequence similarity 69, member A



chr18_-_61089695 1.864 NM_004869
VPS4B
vacuolar protein sorting 4 homolog B (S. cerevisiae)
chr11_-_117186918 1.854 NM_012104
NM_138971
NM_138972
NM_138973
BACE1



beta-site APP-cleaving enzyme 1



chr16_-_4166185 1.828 NM_001116
ADCY9
adenylate cyclase 9
chr10_+_180404 1.809 NM_006624
NM_001202465
NM_001202466
NM_212479
ZMYND11



zinc finger, MYND-type containing 11



chr16_-_68269948 1.803 NM_024939
ESRP2
epithelial splicing regulatory protein 2
chr11_-_117166247 1.792 NM_001207048
NM_001207049
BACE1

beta-site APP-cleaving enzyme 1

chr10_-_15210610 1.775 NM_004808
NMT2
N-myristoyltransferase 2
chr17_-_1090562 1.715 NM_001159746
ABR
active BCR-related gene
chr1_+_101702304 1.713 NM_001400
S1PR1
sphingosine-1-phosphate receptor 1
chr4_-_85887543 1.696 NM_014991
WDFY3
WD repeat and FYVE domain containing 3
chr2_-_101767714 1.675 NM_001102426
TBC1D8
TBC1 domain family, member 8 (with GRAM domain)
chr10_+_6186758 1.658 NM_001145443
PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr2_-_122042767 1.627 NM_014553
TFCP2L1
transcription factor CP2-like 1
chr14_+_90863302 1.611 NM_006888
CALM1
calmodulin 1 (phosphorylase kinase, delta)
chr3_-_18480203 1.603 NM_001131010
SATB1
SATB homeobox 1
chr3_-_66550844 1.557 NM_015541
LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chr1_-_185286460 1.553 NM_006469
IVNS1ABP
influenza virus NS1A binding protein
chr2_+_46524448 1.553 NM_001430
EPAS1
endothelial PAS domain protein 1
chr15_+_99645152 1.519 NM_015286
NM_145728
SYNM

synemin, intermediate filament protein

chr1_-_201438150 1.515 NM_012396
PHLDA3
pleckstrin homology-like domain, family A, member 3
chr4_-_10118500 1.512 NM_005112
NM_017491
WDR1

WD repeat domain 1

chr11_-_65667860 1.508 NM_005438
FOSL1
FOS-like antigen 1
chr11_-_46722115 1.505 NM_004308
ARHGAP1
Rho GTPase activating protein 1
chr17_+_68165660 1.494 NM_000891
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr8_-_103667882 1.494 NM_005655
KLF10
Kruppel-like factor 10
chr7_-_45960738 1.492 NM_000598
NM_001013398
IGFBP3

insulin-like growth factor binding protein 3

chr17_-_1012257 1.476 NM_001092
ABR
active BCR-related gene
chr10_+_181410 1.456 NM_001202464
ZMYND11
zinc finger, MYND-type containing 11
chr4_-_56412968 1.452 NM_004898
CLOCK
clock homolog (mouse)
chr11_+_12132063 1.451 NM_014632
MICAL2
microtubule associated monoxygenase, calponin and LIM domain containing 2
chr6_+_25279651 1.435 NM_001173977
NM_017640
LRRC16A

leucine rich repeat containing 16A

chr10_+_63661012 1.420 NM_032199
ARID5B
AT rich interactive domain 5B (MRF1-like)
chr18_-_48724031 1.409 NM_016626
MEX3C
mex-3 homolog C (C. elegans)
chr2_-_242255114 1.409 NM_005336
HDLBP
high density lipoprotein binding protein
chr1_+_84609941 1.407 NM_182948
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr1_+_7831326 1.404 NM_004781
VAMP3
vesicle-associated membrane protein 3 (cellubrevin)
chr17_+_4736612 1.375 NM_001024937
NM_015716
NM_153827
NM_170663
MINK1



misshapen-like kinase 1



chr1_-_153958688 1.364 NM_002870
RAB13
RAB13, member RAS oncogene family
chr3_+_171757413 1.340 NM_022763
FNDC3B
fibronectin type III domain containing 3B
chr10_+_104503724 1.327 NM_001083913
C10orf26
chromosome 10 open reading frame 26
chr2_+_102770401 1.325 NM_000877
IL1R1
interleukin 1 receptor, type I
chr3_-_11685395 1.321 NM_001128219
VGLL4
vestigial like 4 (Drosophila)
chr9_-_79520878 1.320 NM_015225
PRUNE2
prune homolog 2 (Drosophila)
chr1_-_169336999 1.316 NM_013330
NM_197972
NME7

non-metastatic cells 7, protein expressed in (nucleoside-diphosphate kinase)

chr11_-_17191287 1.316 NM_002645
PIK3C2A
phosphoinositide-3-kinase, class 2, alpha polypeptide
chr17_+_18218569 1.314 NM_144775
SMCR8
Smith-Magenis syndrome chromosome region, candidate 8
chr22_-_37915209 1.298 NM_014550
CARD10
caspase recruitment domain family, member 10
chr14_+_59655351 1.296 NM_014992
DAAM1
dishevelled associated activator of morphogenesis 1
chr2_-_202316227 1.294 NM_015049
TRAK2
trafficking protein, kinesin binding 2
chr14_-_54955714 1.291 NM_004124
GMFB
glia maturation factor, beta
chr9_-_26947435 1.289 NM_001031689
PLAA
phospholipase A2-activating protein
chr20_-_36152952 1.286 NM_001167823
BLCAP
bladder cancer associated protein
chr3_-_11761946 1.279 NM_014667
VGLL4
vestigial like 4 (Drosophila)
chr20_+_57264186 1.265 NM_001204872
NM_001204873
NPEPL1

aminopeptidase-like 1

chr5_-_150460599 1.256 NM_001252385
NM_001252386
NM_001252393
NM_006058
TNIP1



TNFAIP3 interacting protein 1



chr13_-_25861608 1.241 NM_004685
MTMR6
myotubularin related protein 6
chr7_+_45614081 1.237 NM_021116
ADCY1
adenylate cyclase 1 (brain)
chr10_+_95256348 1.234 NM_001127182
NM_018131
CEP55

centrosomal protein 55kDa

chr1_-_43424834 1.228 NM_006516
SLC2A1
solute carrier family 2 (facilitated glucose transporter), member 1
chr13_-_38172862 1.225 NM_001135934
NM_001135935
NM_001135936
NM_006475
POSTN



periostin, osteoblast specific factor



chr8_+_87354958 1.212 NM_007013
WWP1
WW domain containing E3 ubiquitin protein ligase 1
chr3_-_18466759 1.199 NM_001195470
NM_002971
SATB1

SATB homeobox 1

chr10_-_3827418 1.197 NM_001160124
NM_001160125
NM_001300
KLF6


Kruppel-like factor 6


chr12_-_110318178 1.192 NM_016433
GLTP
glycolipid transfer protein
chr8_+_132916339 1.190 NM_015137
EFR3A
EFR3 homolog A (S. cerevisiae)
chr4_-_120549115 1.186 NM_033437
PDE5A
phosphodiesterase 5A, cGMP-specific
chr5_-_176899870 1.183 NM_080881
DBN1
drebrin 1
chr1_+_236305831 1.180 NM_003272
GPR137B
G protein-coupled receptor 137B
chr4_-_120548329 1.178 NM_033430
PDE5A
phosphodiesterase 5A, cGMP-specific
chr19_+_41770057 1.160 NM_007040
HNRNPUL1
heterogeneous nuclear ribonucleoprotein U-like 1
chr8_+_11141983 1.154 NM_015458
MTMR9
myotubularin related protein 9
chr13_+_35516390 1.154 NM_015678
NBEA
neurobeachin
chr4_+_75230856 1.148 NM_001432
EREG
epiregulin
chr1_+_39547088 1.120 NM_012090
MACF1
microtubule-actin crosslinking factor 1
chr6_+_1390068 1.118 NM_001452
FOXF2
forkhead box F2
chr17_+_28705922 1.115 NM_001304
CPD
carboxypeptidase D
chr2_-_39664129 1.109 NM_003618
MAP4K3
mitogen-activated protein kinase kinase kinase kinase 3
chr3_-_9291251 1.100 NM_001033117
NM_014850
SRGAP3

SLIT-ROBO Rho GTPase activating protein 3

chr7_+_106809405 1.096 NM_001244262
NM_012257
HBP1

HMG-box transcription factor 1

chr8_-_93029864 1.083 NM_175636
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr8_+_70378858 1.063 NM_001128204
NM_015170
SULF1

sulfatase 1

chrY_+_15016018 1.043 NM_001122665
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr11_-_8985955 1.039 NM_020644
TMEM9B
TMEM9 domain family, member B
chr8_-_93115453 1.034 NM_001198633
NM_175634
RUNX1T1

runt-related transcription factor 1; translocated to, 1 (cyclin D-related)

chr2_+_189156395 1.024 NM_001252668
NM_001252669
NM_016315
GULP1


GULP, engulfment adaptor PTB domain containing 1


chr3_+_179370779 1.010 NM_003940
USP13
ubiquitin specific peptidase 13 (isopeptidase T-3)
chr3_+_49506079 0.997 NM_001177643
DAG1
dystroglycan 1 (dystrophin-associated glycoprotein 1)
chr10_-_125851850 0.992 NM_014863
NM_015892
CHST15

carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15

chr8_-_93111915 0.990 NM_001198628
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr17_+_4843585 0.980 NM_015528
RNF167
ring finger protein 167
chr9_-_16870719 0.976 NM_017637
BNC2
basonuclin 2
chr1_+_51701943 0.958 NM_014372
RNF11
ring finger protein 11

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.71 2.00e-02 GO:0007165 signal transduction
1.41 2.42e-02 GO:0050794 regulation of cellular process
1.64 3.86e-02 GO:0023052 signaling
1.37 4.51e-02 GO:0050789 regulation of biological process
2.98 4.66e-02 GO:0042060 wound healing

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.80 7.95e-05 GO:0005886 plasma membrane
1.77 1.35e-04 GO:0071944 cell periphery
3.79 2.70e-03 GO:0009986 cell surface

Nothing significant found in function category.