Motif ID: HBP1_HMGB_SSRP1_UBTF.p2

Z-value: 2.269


Transcription factors associated with HBP1_HMGB_SSRP1_UBTF.p2:

Gene SymbolEntrez IDGene Name
HBP1 26959 HMG-box transcription factor 1
HMGB2 3148 high-mobility group box 2
HMGB3 3149 high-mobility group box 3
SSRP1 6749 structure specific recognition protein 1
UBTF 7343 upstream binding transcription factor, RNA polymerase I

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HBP1chr7_+_1068094050.783.3e-04Click!
SSRP1chr11_-_57103324-0.693.2e-03Click!
UBTFchr17_-_42297037,
chr17_-_42298228		-0.647.9e-03Click!
HMGB3chrX_+_150151757-0.283.0e-01Click!
HMGB2chr4_-_1742547300.068.2e-01Click!


Activity profile for motif HBP1_HMGB_SSRP1_UBTF.p2.

activity profile for motif HBP1_HMGB_SSRP1_UBTF.p2


Sorted Z-values histogram for motif HBP1_HMGB_SSRP1_UBTF.p2

Sorted Z-values for motif HBP1_HMGB_SSRP1_UBTF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HBP1_HMGB_SSRP1_UBTF.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_-_111091947 8.540 NM_001142483
 C5orf13
chromosome 5 open reading frame 13
chr7_+_134464417 7.719 CALD1
caldesmon 1
chr6_+_12290528 6.866 NM_001168319
NM_001955
 EDN1

endothelin 1

chr7_+_102553343 6.695 NM_001031692
NM_005824
 LRRC17

leucine rich repeat containing 17

chr10_+_63661012 5.797 NM_032199
 ARID5B
AT rich interactive domain 5B (MRF1-like)
chr18_-_52988916 5.545 NM_001243234
NM_001243235
 TCF4

transcription factor 4

chr3_-_114790221 5.398 NM_001164343
 ZBTB20
zinc finger and BTB domain containing 20
chr6_+_114178516 5.072 NM_002356
 MARCKS
myristoylated alanine-rich protein kinase C substrate
chr1_+_86046434 5.038 NM_001554
 CYR61
cysteine-rich, angiogenic inducer, 61
chr18_-_53071225 4.870 NM_001243232
 TCF4
transcription factor 4
chrX_-_99891690 4.677 NM_003270
 TSPAN6
tetraspanin 6
chr10_+_70847857 4.580 SRGN
serglycin
chr1_-_193155723 4.565 NM_003783
 B3GALT2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr10_+_70847817 4.555 NM_002727
 SRGN
serglycin
chr2_-_56151273 4.502 NM_001039348
NM_001039349
 EFEMP1

EGF containing fibulin-like extracellular matrix protein 1

chr6_+_89790464 4.483 PNRC1
proline-rich nuclear receptor coactivator 1
chr1_+_84647342 4.415 NM_001242862
 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr6_+_89790412 4.357 NM_006813
 PNRC1
proline-rich nuclear receptor coactivator 1
chr4_-_186877413 4.275 SORBS2
sorbin and SH3 domain containing 2
chr7_-_27205148 4.226 NM_152739
 HOXA9
homeobox A9

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 36 entries
Enrichment   P-value GO Accession GO Term
11.03 1.50e-02 GO:0030049 muscle filament sliding
11.03 1.50e-02 GO:0033275 actin-myosin filament sliding
10.74 1.76e-02 GO:0070252 actin-mediated cell contraction
9.49 3.66e-02 GO:0090090 negative regulation of canonical Wnt receptor signaling pathway
9.07 4.77e-02 GO:0010594 regulation of endothelial cell migration
8.12 5.93e-03 GO:0030178 negative regulation of Wnt receptor signaling pathway
7.91 5.09e-04 GO:0030198 extracellular matrix organization
6.36 3.87e-03 GO:0030111 regulation of Wnt receptor signaling pathway
6.19 4.49e-02 GO:0031589 cell-substrate adhesion
5.85 1.24e-04 GO:0007517 muscle organ development
5.67 3.89e-03 GO:0043062 extracellular structure organization
4.86 7.02e-03 GO:0003012 muscle system process
4.86 1.71e-02 GO:0006936 muscle contraction
4.72 3.02e-04 GO:0061061 muscle structure development
4.70 3.20e-04 GO:0001568 blood vessel development
4.37 8.28e-04 GO:0001944 vasculature development
4.28 2.56e-02 GO:0048514 blood vessel morphogenesis
3.92 1.44e-02 GO:0030029 actin filament-based process
3.61 3.77e-04 GO:0072358 cardiovascular system development
3.61 3.77e-04 GO:0072359 circulatory system development

Gene overrepresentation in compartment category:

Showing 1 to 20 of 20 entries
Enrichment   P-value GO Accession GO Term
14.43 6.63e-05 GO:0005581 collagen
8.33 3.15e-06 GO:0044420 extracellular matrix part
7.56 2.16e-02 GO:0016459 myosin complex
7.46 1.81e-03 GO:0030027 lamellipodium
6.19 8.76e-05 GO:0005912 adherens junction
6.05 8.42e-03 GO:0005925 focal adhesion
5.89 3.54e-03 GO:0030016 myofibril
5.83 1.22e-08 GO:0005578 proteinaceous extracellular matrix
5.79 1.15e-02 GO:0005924 cell-substrate adherens junction
5.56 2.78e-04 GO:0070161 anchoring junction
5.56 1.55e-02 GO:0030055 cell-substrate junction
5.54 4.32e-02 GO:0030017 sarcomere
5.52 5.97e-03 GO:0043292 contractile fiber
5.39 1.91e-02 GO:0044449 contractile fiber part
5.06 6.63e-08 GO:0031012 extracellular matrix
4.21 2.22e-04 GO:0015629 actin cytoskeleton
2.77 8.50e-06 GO:0044421 extracellular region part
2.71 2.03e-02 GO:0030054 cell junction
2.46 6.86e-03 GO:0005615 extracellular space
2.06 4.94e-04 GO:0005576 extracellular region

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
Enrichment   P-value GO Accession GO Term
13.61 1.15e-04 GO:0005518 collagen binding
9.96 4.96e-03 GO:0008307 structural constituent of muscle
8.01 1.19e-03 GO:0005201 extracellular matrix structural constituent
4.52 1.80e-05 GO:0003779 actin binding
3.38 1.07e-04 GO:0008092 cytoskeletal protein binding
1.30 1.45e-02 GO:0005515 protein binding