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Motif ID: HBP1_HMGB_SSRP1_UBTF.p2

Z-value: 2.269

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr5_-_111091947	8.540	NM_001142483	C5orf13	chromosome 5 open reading frame 13
chr7_+_134464417	7.719		CALD1	caldesmon 1
chr6_+_12290528	6.866	NM_001168319 NM_001955	EDN1	endothelin 1
chr7_+_102553343	6.695	NM_001031692 NM_005824	LRRC17	leucine rich repeat containing 17
chr10_+_63661012	5.797	NM_032199	ARID5B	AT rich interactive domain 5B (MRF1-like)
chr18_-_52988916	5.545	NM_001243234 NM_001243235	TCF4	transcription factor 4
chr3_-_114790221	5.398	NM_001164343	ZBTB20	zinc finger and BTB domain containing 20
chr6_+_114178516	5.072	NM_002356	MARCKS	myristoylated alanine-rich protein kinase C substrate
chr1_+_86046434	5.038	NM_001554	CYR61	cysteine-rich, angiogenic inducer, 61
chr18_-_53071225	4.870	NM_001243232	TCF4	transcription factor 4
chrX_-_99891690	4.677	NM_003270	TSPAN6	tetraspanin 6
chr10_+_70847857	4.580		SRGN	serglycin
chr1_-_193155723	4.565	NM_003783	B3GALT2	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr10_+_70847817	4.555	NM_002727	SRGN	serglycin
chr2_-_56151273	4.502	NM_001039348 NM_001039349	EFEMP1	EGF containing fibulin-like extracellular matrix protein 1
chr6_+_89790464	4.483		PNRC1	proline-rich nuclear receptor coactivator 1
chr1_+_84647342	4.415	NM_001242862	PRKACB	protein kinase, cAMP-dependent, catalytic, beta
chr6_+_89790412	4.357	NM_006813	PNRC1	proline-rich nuclear receptor coactivator 1
chr4_-_186877413	4.275		SORBS2	sorbin and SH3 domain containing 2
chr7_-_27205148	4.226	NM_152739	HOXA9	homeobox A9
chr7_-_47621635	4.140		TNS3	tensin 3
chr13_-_110959441	4.019	NM_001845	COL4A1	collagen, type IV, alpha 1
chr7_-_47621741	3.946	NM_022748	TNS3	tensin 3
chr18_-_53177999	3.932	NM_001243231	TCF4	transcription factor 4
chr11_+_112831968	3.717	NM_000615 NM_001076682 NM_001242607 NM_001242608 NM_181351	NCAM1	neural cell adhesion molecule 1
chr8_+_70405080	3.684		SULF1	sulfatase 1
chr3_-_114478117	3.597	NM_001164344 NM_001164345	ZBTB20	zinc finger and BTB domain containing 20
chr2_-_216259197	3.566		FN1	fibronectin 1
chr1_-_85930610	3.565		DDAH1	dimethylarginine dimethylaminohydrolase 1
chr4_-_186732047	3.540	NM_001145672	SORBS2	sorbin and SH3 domain containing 2
chr4_-_186577858	3.476		SORBS2	sorbin and SH3 domain containing 2
chr5_-_121414011	3.469	NM_002317	LOX	lysyl oxidase
chr18_-_53257033	3.444	NM_001243227 NM_001243228	TCF4	transcription factor 4
chr1_-_86043932	3.427	NM_001134445	DDAH1	dimethylarginine dimethylaminohydrolase 1
chr4_-_101439071	3.410	NM_001159694 NM_016242	EMCN	endomucin
chr4_+_146403955	3.408	NM_001003688	SMAD1	SMAD family member 1
chrX_+_135251795	3.399	NM_001167819	FHL1	four and a half LIM domains 1
chr8_+_70405027	3.193	NM_001128205 NM_001128206	SULF1	sulfatase 1
chr5_+_15500288	3.150	NM_012304	FBXL7	F-box and leucine-rich repeat protein 7
chrX_+_135251454	3.104	NM_001159704	FHL1	four and a half LIM domains 1
chr18_+_72922725	3.099	NM_005786	TSHZ1	teashirt zinc finger homeobox 1
chr1_+_81771844	3.082		LPHN2	latrophilin 2
chr7_-_47622127	3.008		TNS3	tensin 3
chr4_+_78078332	2.993	NM_004354	CCNG2	cyclin G2
chr7_-_27205123	2.920		HOXA9	homeobox A9
chr4_-_111558150	2.915		PITX2	paired-like homeodomain 2
chr7_+_93551015	2.815	NM_004126	GNG11	guanine nucleotide binding protein (G protein), gamma 11
chr9_-_14313899	2.781		NFIB	nuclear factor I/B
chr5_-_39424930	2.752		DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr12_+_13349720	2.751		EMP1	epithelial membrane protein 1
chr7_+_134464372	2.708		CALD1	caldesmon 1
chr11_+_19372270	2.671	NM_001111018	NAV2	neuron navigator 2
chr5_-_39425297	2.656	NM_001244871 NM_001343	DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr4_-_186732208	2.642	NM_001145671	SORBS2	sorbin and SH3 domain containing 2
chr2_-_152590983	2.632	NM_001164507 NM_001164508 NM_004543	NEB	nebulin
chrX_-_13835187	2.632		GPM6B	glycoprotein M6B
chr4_+_78078394	2.619		CCNG2	cyclin G2
chr1_-_201476218	2.557		CSRP1	cysteine and glycine-rich protein 1
chr8_+_26435920	2.546	NM_001244604	DPYSL2	dihydropyrimidinase-like 2
chr6_+_148663728	2.492	NM_015278	SASH1	SAM and SH3 domain containing 1
chrX_-_13835012	2.481		GPM6B	glycoprotein M6B
chr3_-_114343052	2.475	NM_001164347	ZBTB20	zinc finger and BTB domain containing 20
chr9_+_116343169	2.441		RGS3	regulator of G-protein signaling 3
chr2_-_188312872	2.436	NM_005795	CALCRL	calcitonin receptor-like
chr7_+_134576150	2.434	NM_033139 NM_033140	CALD1	caldesmon 1
chr7_-_131241321	2.412	NM_001018111 NM_005397	PODXL	podocalyxin-like
chr9_+_116342939	2.400	NM_021106	RGS3	regulator of G-protein signaling 3
chr1_-_95392501	2.396	NM_001839	CNN3	calponin 3, acidic
chr5_-_168271852	2.383
chr6_+_148664124	2.382		SASH1	SAM and SH3 domain containing 1
chr2_+_189839132	2.323		COL3A1	collagen, type III, alpha 1
chr2_-_175869910	2.311	NM_001822 NM_001025201	CHN1	chimerin (chimaerin) 1
chr6_-_11232901	2.307	NM_006403 NM_182966	NEDD9	neural precursor cell expressed, developmentally down-regulated 9
chr4_+_90816002	2.286	NM_007351	MMRN1	multimerin 1
chr9_-_16727887	2.274		BNC2	basonuclin 2
chr2_-_190927321	2.266	NM_005259	MSTN	myostatin
chr3_-_99594915	2.252	NM_014890	FILIP1L	filamin A interacting protein 1-like
chr6_+_148663953	2.248		SASH1	SAM and SH3 domain containing 1
chr5_-_111092918	2.239	NM_004772	C5orf13	chromosome 5 open reading frame 13
chr5_-_121413967	2.231		LOX	lysyl oxidase
chr7_+_134464161	2.225	NM_004342 NM_033138 NM_033157	CALD1	caldesmon 1
chr12_-_6233684	2.221	NM_000552	VWF	von Willebrand factor
chr7_+_116165043	2.202	NM_001172895	CAV1	caveolin 1, caveolae protein, 22kDa
chr21_-_28339405	2.202	NM_007038	ADAMTS5	ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr18_-_53089722	2.170	NM_001243233	TCF4	transcription factor 4
chr5_-_121413906	2.154		LOX	lysyl oxidase
chr5_-_111312522	2.154	NM_001142474 NM_001142475	C5orf13	chromosome 5 open reading frame 13
chr1_-_201476241	2.133		CSRP1	cysteine and glycine-rich protein 1
chr1_-_201475966	2.126	NM_001193571	CSRP1	cysteine and glycine-rich protein 1
chr9_+_116263706	2.123	NM_130795	RGS3	regulator of G-protein signaling 3
chr12_-_91505541	2.108	NM_002345	LUM	lumican
chr1_-_201476248	2.104	NM_001193570 NM_004078	CSRP1	cysteine and glycine-rich protein 1
chr2_+_69240137	2.101	NM_018153 NM_032208 NM_053034	ANTXR1	anthrax toxin receptor 1
chr9_-_14313509	2.100		NFIB	nuclear factor I/B
chr5_+_86563594	2.096		RASA1	RAS p21 protein activator (GTPase activating protein) 1
chr14_-_89883306	2.072	NM_005197	FOXN3	forkhead box N3
chr2_-_163099877	2.054	NM_004460	FAP	fibroblast activation protein, alpha
chr7_-_111846384	2.039	NM_014705	DOCK4	dedicator of cytokinesis 4
chr7_+_116165089	2.028		CAV1	caveolin 1, caveolae protein, 22kDa
chr12_-_91505215	2.009		LUM	lumican
chr3_-_55521567	2.007		WNT5A	wingless-type MMTV integration site family, member 5A
chr7_+_94297448	2.004		PEG10	paternally expressed 10
chr10_-_91102430	2.002		LIPA	lipase A, lysosomal acid, cholesterol esterase
chr4_-_186578122	1.998	NM_001145674 NM_001145675	SORBS2	sorbin and SH3 domain containing 2
chr16_+_66400524	1.979	NM_001795	CDH5	cadherin 5, type 2 (vascular endothelium)
chr1_+_100111430	1.964	NM_017734	PALMD	palmdelphin
chr6_-_11232883	1.962		NEDD9	neural precursor cell expressed, developmentally down-regulated 9
chr12_-_91573264	1.951	NM_133503	DCN	decorin
chr2_+_36583369	1.919	NM_016441	CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr5_-_111092865	1.906		C5orf13	chromosome 5 open reading frame 13
chr14_+_105941061	1.904	NM_001312	CRIP2	cysteine-rich protein 2
chr5_-_39425030	1.901		DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr8_-_82395401	1.890	NM_001442	FABP4	fatty acid binding protein 4, adipocyte
chr3_-_149688886	1.885		PFN2	profilin 2
chr2_+_102508333	1.874		MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4
chr15_-_35087748	1.868	NM_005159	ACTC1	actin, alpha, cardiac muscle 1
chr7_+_134576187	1.867		CALD1	caldesmon 1
chr2_-_151344145	1.864	NM_005168	RND3	Rho family GTPase 3
chr13_-_33780142	1.858	NM_001243474 NM_052851	STARD13	StAR-related lipid transfer (START) domain containing 13
chr2_+_148602050	1.839		ACVR2A	activin A receptor, type IIA
chr3_+_158787040	1.829	NM_001197113 NM_001197114 NM_001042705 NM_001042706 NM_001197100	IQCJ-SCHIP1 IQCJ	IQCJ-SCHIP1 readthrough IQ motif containing J
chr2_+_102508377	1.823		MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4
chrX_-_100914816	1.818	NM_014782 NM_177949	ARMCX2	armadillo repeat containing, X-linked 2
chrX_+_51927918	1.804	NM_001098800 NM_001242362 NM_030801 NM_177535 NM_177537	MAGED4 MAGED4B	melanoma antigen family D, 4 melanoma antigen family D, 4B
chrX_+_114795176	1.798	NM_005032	PLS3	plastin 3
chr21_+_35190586	1.795		ITSN1	intersectin 1 (SH3 domain protein)
chr7_-_107643330	1.787	NM_002291	LAMB1	laminin, beta 1
chr3_-_99833348	1.785	NM_001042459 NM_182909	FILIP1L	filamin A interacting protein 1-like
chr4_-_40936640	1.773		APBB2	amyloid beta (A4) precursor protein-binding, family B, member 2
chr8_-_18666295	1.771	NM_206909	PSD3	pleckstrin and Sec7 domain containing 3
chr9_+_36036900	1.771	NM_021111	RECK	reversion-inducing-cysteine-rich protein with kazal motifs
chr14_-_52535737	1.749		NID2	nidogen 2 (osteonidogen)
chr1_+_155853546	1.714		SYT11	synaptotagmin XI
chr14_-_92413738	1.712		FBLN5	fibulin 5
chr1_-_57045129	1.696		PPAP2B	phosphatidic acid phosphatase type 2B
chr6_-_128841432	1.692	NM_002844 NM_001135648	PTPRK	protein tyrosine phosphatase, receptor type, K
chr14_-_23288912	1.673	NM_001126106	SLC7A7	solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr18_-_53255361	1.666		TCF4	transcription factor 4
chr3_-_149421059	1.665	NM_001168278	WWTR1	WW domain containing transcription regulator 1
chr12_-_16757944	1.655		LMO3	LIM domain only 3 (rhombotin-like 2)
chr12_-_10251520	1.653	NM_016511	CLEC1A	C-type lectin domain family 1, member A
chr1_-_244006471	1.649	NM_005465 NM_181690	AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
chr4_+_41258909	1.643		UCHL1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr15_+_25200069	1.629	NM_003097 NM_022804 NM_005678	SNRPN SNURF	small nuclear ribonucleoprotein polypeptide N SNRPN upstream reading frame
chr7_+_116164838	1.627	NM_001753	CAV1	caveolin 1, caveolae protein, 22kDa
chr1_+_163038564	1.621	NM_005613	RGS4	regulator of G-protein signaling 4
chr5_+_140739589	1.621	NM_018923 NM_032096	PCDHGB2	protocadherin gamma subfamily B, 2
chr3_-_55521330	1.615	NM_003392	WNT5A	wingless-type MMTV integration site family, member 5A
chr12_-_91576579	1.611		DCN	decorin
chr9_-_14314036	1.609	NM_001190737 NM_005596	NFIB	nuclear factor I/B
chr13_-_48987247	1.604		LPAR6	lysophosphatidic acid receptor 6
chrX_-_51812249	1.600	NM_001098800 NM_001242362 NM_030801 NM_177535 NM_177537	MAGED4 MAGED4B	melanoma antigen family D, 4 melanoma antigen family D, 4B
chr22_+_38598065	1.600		MAFF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
chr3_+_154797644	1.599	NM_007287	MME	membrane metallo-endopeptidase
chr11_-_2162340	1.597	NM_001127598	IGF2	insulin-like growth factor 2 (somatomedin A)
chr2_-_218843541	1.587		TNS1	tensin 1
chr1_-_95392449	1.586		CNN3	calponin 3, acidic
chr8_-_6420454	1.582	NM_001118887 NM_001118888 NM_001147	ANGPT2	angiopoietin 2
chr3_+_154797435	1.581	NM_000902	MME	membrane metallo-endopeptidase
chr4_+_41258895	1.580	NM_004181	UCHL1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr3_-_145879222	1.567	NM_000935 NM_182943	PLOD2	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr14_-_52535765	1.559		NID2	nidogen 2 (osteonidogen)
chr1_+_151032683	1.552		MLLT11	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr14_+_85996454	1.551	NM_013231	FLRT2	fibronectin leucine rich transmembrane protein 2
chr13_-_48987017	1.537		LPAR6	lysophosphatidic acid receptor 6
chr22_+_38092994	1.524	NM_001039141	TRIOBP	TRIO and F-actin binding protein
chr22_+_38599026	1.521	NM_001161573	MAFF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
chr16_+_55515468	1.514	NM_001127891	MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr1_-_68697997	1.491	NM_001002292 NM_001193334 NM_024911	WLS	wntless homolog (Drosophila)
chr12_+_13349601	1.486	NM_001423	EMP1	epithelial membrane protein 1
chr3_+_62305395	1.485	NM_020685	C3orf14	chromosome 3 open reading frame 14
chr14_-_52535711	1.478		NID2	nidogen 2 (osteonidogen)
chr2_+_33359607	1.476	NM_000627 NM_001166264 NM_001166265 NM_001166266	LTBP1	latent transforming growth factor beta binding protein 1
chr1_-_57045214	1.459		PPAP2B	phosphatidic acid phosphatase type 2B
chr1_+_84630374	1.456		PRKACB	protein kinase, cAMP-dependent, catalytic, beta
chr20_+_19870209	1.454	NM_018993	RIN2	Ras and Rab interactor 2
chr5_-_39394423	1.451		DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr1_+_244216506	1.450	NM_006352	ZNF238	zinc finger protein 238
chr1_-_57045235	1.444	NM_003713	PPAP2B	phosphatidic acid phosphatase type 2B
chr3_-_127541160	1.441	NM_007283	MGLL	monoglyceride lipase
chr6_-_134498973	1.439	NM_001143677	SGK1	serum/glucocorticoid regulated kinase 1
chr17_-_10452939	1.437	NM_001100112 NM_017534	MYH2	myosin, heavy chain 2, skeletal muscle, adult
chr1_+_151032866	1.435		MLLT11	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr8_+_79428335	1.419	NM_006823 NM_181839	PKIA	protein kinase (cAMP-dependent, catalytic) inhibitor alpha
chr14_+_21156922	1.416	NM_001097577 NM_194431	ANG RNASE4	angiogenin, ribonuclease, RNase A family, 5 ribonuclease, RNase A family, 4
chr12_-_49319211	1.415	NM_001143782 NM_016594	FKBP11	FK506 binding protein 11, 19 kDa
chr13_-_48987652	1.402	NM_001162498	LPAR6	lysophosphatidic acid receptor 6
chr18_+_7946885	1.400		PTPRM	protein tyrosine phosphatase, receptor type, M
chr1_+_66458389	1.398	NM_001037340	PDE4B	phosphodiesterase 4B, cAMP-specific
chrX_+_100333835	1.391	NM_021637	TMEM35	transmembrane protein 35
chr8_+_79578258	1.387	NM_016010	FAM164A	family with sequence similarity 164, member A
chr22_-_19512859	1.384	NM_001130861 NM_003277	CLDN5	claudin 5
chr7_+_94292816	1.379		PEG10	paternally expressed 10
chrX_-_10645726	1.376	NM_001098624	MID1	midline 1 (Opitz/BBB syndrome)
chr1_+_151032880	1.372		MLLT11	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr10_+_54074037	1.371	NM_012242	DKK1	dickkopf 1 homolog (Xenopus laevis)
chr5_-_16936371	1.369	NM_012334	MYO10	myosin X
chr13_+_98795468	1.366		FARP1	FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr3_-_149095458	1.363		TM4SF1	transmembrane 4 L six family member 1
chr8_-_17579729	1.351	NM_001001931	MTUS1	microtubule associated tumor suppressor 1

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
2.67	4.36e-07	GO:0009653	anatomical structure morphogenesis
1.87	4.51e-05	GO:0048856	anatomical structure development
1.75	1.07e-04	GO:0032502	developmental process
5.85	1.24e-04	GO:0007517	muscle organ development
1.89	1.66e-04	GO:0048731	system development
1.78	2.87e-04	GO:0007275	multicellular organismal development
4.72	3.02e-04	GO:0061061	muscle structure development
4.70	3.20e-04	GO:0001568	blood vessel development
3.61	3.77e-04	GO:0072358	cardiovascular system development
3.61	3.77e-04	GO:0072359	circulatory system development
7.91	5.09e-04	GO:0030198	extracellular matrix organization
2.97	6.40e-04	GO:0007155	cell adhesion
2.97	6.40e-04	GO:0022610	biological adhesion
4.37	8.28e-04	GO:0001944	vasculature development
6.36	3.87e-03	GO:0030111	regulation of Wnt receptor signaling pathway
5.67	3.89e-03	GO:0043062	extracellular structure organization
2.01	4.00e-03	GO:0048513	organ development
2.98	4.84e-03	GO:0032989	cellular component morphogenesis
1.52	5.27e-03	GO:0032501	multicellular organismal process
8.12	5.93e-03	GO:0030178	negative regulation of Wnt receptor signaling pathway
2.10	6.18e-03	GO:0023051	regulation of signaling
4.86	7.02e-03	GO:0003012	muscle system process
1.98	8.34e-03	GO:0048583	regulation of response to stimulus
2.17	9.86e-03	GO:0009966	regulation of signal transduction
2.51	1.38e-02	GO:0040011	locomotion
3.92	1.44e-02	GO:0030029	actin filament-based process
11.03	1.50e-02	GO:0030049	muscle filament sliding
11.03	1.50e-02	GO:0033275	actin-myosin filament sliding
4.86	1.71e-02	GO:0006936	muscle contraction
10.74	1.76e-02	GO:0070252	actin-mediated cell contraction
2.86	2.48e-02	GO:0000902	cell morphogenesis
4.28	2.56e-02	GO:0048514	blood vessel morphogenesis
3.01	3.21e-02	GO:0000904	cell morphogenesis involved in differentiation
9.49	3.66e-02	GO:0090090	negative regulation of canonical Wnt receptor signaling pathway
6.19	4.49e-02	GO:0031589	cell-substrate adhesion
9.07	4.77e-02	GO:0010594	regulation of endothelial cell migration

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
5.83	1.22e-08	GO:0005578	proteinaceous extracellular matrix
5.06	6.63e-08	GO:0031012	extracellular matrix
8.33	3.15e-06	GO:0044420	extracellular matrix part
2.77	8.50e-06	GO:0044421	extracellular region part
14.43	6.63e-05	GO:0005581	collagen
6.19	8.76e-05	GO:0005912	adherens junction
4.21	2.22e-04	GO:0015629	actin cytoskeleton
5.56	2.78e-04	GO:0070161	anchoring junction
2.06	4.94e-04	GO:0005576	extracellular region
7.46	1.81e-03	GO:0030027	lamellipodium
5.89	3.54e-03	GO:0030016	myofibril
5.52	5.97e-03	GO:0043292	contractile fiber
2.46	6.86e-03	GO:0005615	extracellular space
6.05	8.42e-03	GO:0005925	focal adhesion
5.79	1.15e-02	GO:0005924	cell-substrate adherens junction
5.56	1.55e-02	GO:0030055	cell-substrate junction
5.39	1.91e-02	GO:0044449	contractile fiber part
2.71	2.03e-02	GO:0030054	cell junction
7.56	2.16e-02	GO:0016459	myosin complex
5.54	4.32e-02	GO:0030017	sarcomere

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
4.52	1.80e-05	GO:0003779	actin binding
3.38	1.07e-04	GO:0008092	cytoskeletal protein binding
13.61	1.15e-04	GO:0005518	collagen binding
8.01	1.19e-03	GO:0005201	extracellular matrix structural constituent
9.96	4.96e-03	GO:0008307	structural constituent of muscle
1.30	1.45e-02	GO:0005515	protein binding