Motif ID: HLF.p2

Z-value: 1.693


Transcription factors associated with HLF.p2:

Gene SymbolEntrez IDGene Name
HLF 3131 hepatic leukemia factor

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HLFchr17_+_533423200.923.2e-07Click!


Activity profile for motif HLF.p2.

activity profile for motif HLF.p2


Sorted Z-values histogram for motif HLF.p2

Sorted Z-values for motif HLF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HLF.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_+_117085302 7.285 NM_000607
 ORM1
orosomucoid 1
chr9_+_117092068 7.198 NM_000608
 ORM2
orosomucoid 2
chr7_+_45933096 6.985


chr10_-_52645430 6.879 NM_001198818
NM_001198819
NM_001198820
NM_014576
NM_138932
NM_138933
 A1CF





APOBEC1 complementation factor





chr1_-_230849863 6.067 AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr3_+_133494275 5.888 TF
transferrin
chr16_+_72088507 5.413 NM_001126102
NM_005143
 HP

haptoglobin

chr1_-_230849847 5.032 AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr2_-_88427535 5.000 NM_001443
 FABP1
fatty acid binding protein 1, liver
chr16_-_55866972 4.821 CES1
carboxylesterase 1
chr3_+_186330844 4.740 NM_001622
 AHSG
alpha-2-HS-glycoprotein
chr16_-_55867016 4.603 NM_001025194
NM_001025195
NM_001266
 CES1


carboxylesterase 1


chr2_+_113885137 4.497 NM_173842
 IL1RN
interleukin 1 receptor antagonist
chr3_-_49726081 4.245 NM_020998
 MST1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr2_-_99279935 3.883 NM_001160154
 MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr1_+_207262211 3.636 NM_001017365
NM_001017366
 C4BPB

complement component 4 binding protein, beta

chr19_+_35773409 3.563 NM_021175
 HAMP
hepcidin antimicrobial peptide
chr10_-_95360959 3.274 NM_006744
 RBP4
retinol binding protein 4, plasma
chr3_+_186330859 3.214 AHSG
alpha-2-HS-glycoprotein
chr13_-_46679143 3.160 NM_001872
NM_016413
 CPB2

carboxypeptidase B2 (plasma)


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 7 of 7 entries
Enrichment   P-value GO Accession GO Term
207.36 1.20e-02 GO:0006883 cellular sodium ion homeostasis
56.56 8.94e-03 GO:0051917 regulation of fibrinolysis
23.71 1.19e-02 GO:0006953 acute-phase response
17.30 5.04e-03 GO:0072376 protein activation cascade
4.12 1.00e-03 GO:0009611 response to wounding
3.79 2.96e-02 GO:0006952 defense response
2.55 2.56e-03 GO:0006950 response to stress

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
Enrichment   P-value GO Accession GO Term
82.95 2.00e-02 GO:0045179 apical cortex
37.72 2.91e-04 GO:0034364 high-density lipoprotein particle
25.93 1.38e-03 GO:0032994 protein-lipid complex
25.93 1.38e-03 GO:0034358 plasma lipoprotein particle
6.25 1.17e-09 GO:0005615 extracellular space
5.22 9.41e-09 GO:0044421 extracellular region part
3.80 2.97e-08 GO:0005576 extracellular region

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
Enrichment   P-value GO Accession GO Term
69.13 3.23e-02 GO:0030492 hemoglobin binding
19.45 4.53e-02 GO:0005504 fatty acid binding
9.36 1.78e-02 GO:0004252 serine-type endopeptidase activity
8.05 3.58e-02 GO:0008236 serine-type peptidase activity
7.93 3.84e-02 GO:0017171 serine hydrolase activity
4.60 2.97e-02 GO:0008289 lipid binding