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• Activity deltas table
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Motif ID: HNF4A_NR2F1,2.p2

Z-value: 3.941

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr17_+_27370155	14.541		PIPOX	pipecolic acid oxidase
chr14_-_94855120	12.439	NM_000295	SERPINA1	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr6_+_31623668	10.456	NM_019101	APOM	apolipoprotein M
chr12_+_53497273	10.428	NM_003578	SOAT2	sterol O-acyltransferase 2
chr1_-_169555710	10.353	NM_000130	F5	coagulation factor V (proaccelerin, labile factor)
chr1_-_230849847	10.199		AGT	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr6_+_31623688	10.115		APOM	apolipoprotein M
chr12_+_53497287	9.731		SOAT2	sterol O-acyltransferase 2
chr1_-_230849863	9.453		AGT	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr2_-_21266893	9.278		APOB	apolipoprotein B (including Ag(x) antigen)
chr1_-_169555624	9.095		F5	coagulation factor V (proaccelerin, labile factor)
chr6_+_31982538	9.031	NM_001242823 NM_001252204 NM_007293 NM_001002029	LOC100293534 C4A C4B	complement C4-B-like complement component 4A (Rodgers blood group) complement component 4B (Chido blood group)
chr5_-_42811959	8.433	NM_001085486 NM_001093726 NM_005410	SEPP1	selenoprotein P, plasma, 1
chr1_-_161193190	8.040		APOA2	apolipoprotein A-II
chr10_+_102732285	7.759	NM_001203244 NM_017893	SEMA4G	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr17_+_27369917	7.743	NM_016518	PIPOX	pipecolic acid oxidase
chr11_-_116708334	7.634	NM_000039	APOA1	apolipoprotein A-I
chr11_+_46740769	7.585		F2	coagulation factor II (thrombin)
chr11_+_46740736	7.573	NM_000506	F2	coagulation factor II (thrombin)
chr14_-_24777184	7.511		CIDEB	cell death-inducing DFFA-like effector b
chr14_-_24777153	7.449		CIDEB	cell death-inducing DFFA-like effector b
chr17_-_34329083	7.376	NM_032965	CCL15	chemokine (C-C motif) ligand 15
chr3_-_52479042	7.311	NM_020163	SEMA3G	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
chr2_-_21225640	7.139		APOB	apolipoprotein B (including Ag(x) antigen)
chr6_+_31913763	7.105		CFB	complement factor B
chr14_-_24777160	7.048		CIDEB	cell death-inducing DFFA-like effector b
chr1_-_230850335	6.965	NM_000029	AGT	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr17_+_19437140	6.897	NM_018242	SLC47A1	solute carrier family 47, member 1
chr13_+_113777112	6.852	NM_000504	F10	coagulation factor X
chr1_-_173886464	6.712	NM_000488	SERPINC1	serpin peptidase inhibitor, clade C (antithrombin), member 1
chr6_+_31913852	6.429		CFB	complement factor B
chr14_-_94854910	6.338		SERPINA1	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr1_-_173886401	6.244		SERPINC1	serpin peptidase inhibitor, clade C (antithrombin), member 1
chr1_-_161193375	6.192	NM_001643	APOA2	apolipoprotein A-II
chr19_+_35629727	6.189	NM_021902	FXYD1	FXYD domain containing ion transport regulator 1
chr10_+_114133838	6.074	NM_203379	ACSL5	acyl-CoA synthetase long-chain family member 5
chr17_-_7082654	6.002	NM_001197216 NM_001671	ASGR1	asialoglycoprotein receptor 1
chr19_-_6720585	5.924	NM_000064	C3	complement component 3
chr2_-_238499317	5.812		RAB17	RAB17, member RAS oncogene family
chr6_+_31949800	5.720	NM_001242823 NM_001252204 NM_007293 NM_001002029	LOC100293534 C4A C4B	complement C4-B-like complement component 4A (Rodgers blood group) complement component 4B (Chido blood group)
chr6_-_29527477	5.718		UBD	ubiquitin D
chr2_+_219646448	5.460	NM_000784	CYP27A1	cytochrome P450, family 27, subfamily A, polypeptide 1
chr2_+_219283809	5.363	NM_007127	VIL1	villin 1
chr10_+_114133775	5.215		ACSL5	acyl-CoA synthetase long-chain family member 5
chr2_-_238499713	5.171	NM_022449	RAB17	RAB17, member RAS oncogene family
chr3_-_50340979	5.041	NM_007312 NM_033159 NM_153282 NM_153283 NM_153285	HYAL1	hyaluronoglucosaminidase 1
chr4_+_100495972	4.953		MTTP	microsomal triglyceride transfer protein
chr17_-_7018049	4.881	NM_001181 NM_001201352 NM_080912 NM_080913	ASGR2	asialoglycoprotein receptor 2
chrX_-_105282714	4.819	NM_000354	SERPINA7	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr3_-_194072004	4.789	NM_001080513	CPN2	carboxypeptidase N, polypeptide 2
chr3_+_186330711	4.705		AHSG	alpha-2-HS-glycoprotein
chr17_+_4675175	4.550	NM_003963	TM4SF5	transmembrane 4 L six family member 5
chr6_+_31913708	4.508	NM_001710	CFB	complement factor B
chr20_+_56136136	4.502	NM_002591	PCK1	phosphoenolpyruvate carboxykinase 1 (soluble)
chr2_-_88427535	4.472	NM_001443	FABP1	fatty acid binding protein 1, liver
chr19_+_5823817	4.413	NM_004558	NRTN	neurturin
chr22_+_25003610	4.405	NM_001032365	GGT1	gamma-glutamyltransferase 1
chr17_-_7017971	4.345		ASGR2	asialoglycoprotein receptor 2
chr4_+_69962191	4.324	NM_001074	UGT2B7	UDP glucuronosyltransferase 2 family, polypeptide B7
chr17_-_26697224	4.322		VTN	vitronectin
chr19_-_41196419	4.278	NM_004756	NUMBL	numb homolog (Drosophila)-like
chr11_+_73358593	4.225	NM_001130034 NM_001130035	PLEKHB1	pleckstrin homology domain containing, family B (evectins) member 1
chr1_-_110306525	4.187	NM_024526 NM_133181 NM_139053	EPS8L3	EPS8-like 3
chr6_+_31895401	4.176		C2	complement component 2
chr2_-_21266809	4.151		APOB	apolipoprotein B (including Ag(x) antigen)
chr17_+_41006094	4.137		AOC3	amine oxidase, copper containing 3 (vascular adhesion protein 1)
chr4_-_69886112	4.048	NM_001075 NM_001144767	UGT2B10	UDP glucuronosyltransferase 2 family, polypeptide B10
chr19_+_18496966	3.997	NM_004864	GDF15	growth differentiation factor 15
chr14_-_24777064	3.942
chr16_-_87970107	3.933	NM_001739	CA5A	carbonic anhydrase VA, mitochondrial
chr17_-_34328607	3.931		CCL14-CCL15	CCL14-CCL15 readthrough
chr17_+_1646290	3.907	NM_001165920	SERPINF2	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
chr16_-_55867016	3.849	NM_001025194 NM_001025195 NM_001266	CES1	carboxylesterase 1
chr17_+_1646129	3.699	NM_000934 NM_001165921	SERPINF2	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
chr13_+_113760101	3.691	NM_000131 NM_019616	F7	coagulation factor VII (serum prothrombin conversion accelerator)
chr8_+_21916858	3.680		EPB49	erythrocyte membrane protein band 4.9 (dematin)
chr6_+_31895201	3.679	NM_000063 NM_001145903	C2	complement component 2
chr12_+_7169192	3.649
chr2_-_21266915	3.641	NM_000384	APOB	apolipoprotein B (including Ag(x) antigen)
chr17_+_41052813	3.538	NM_000151	G6PC	glucose-6-phosphatase, catalytic subunit
chr16_-_55866972	3.536		CES1	carboxylesterase 1
chr12_-_110939877	3.534	NM_016226 NM_057180	VPS29	vacuolar protein sorting 29 homolog (S. cerevisiae)
chr14_-_65409445	3.458	NM_002083	GPX2	glutathione peroxidase 2 (gastrointestinal)
chr2_+_241544819	3.449	NM_001195381 NM_001195382	GPR35	G protein-coupled receptor 35
chr10_+_101542554	3.407		ABCC2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr19_-_51869632	3.402	NM_001985	ETFB	electron-transfer-flavoprotein, beta polypeptide
chr2_+_11674241	3.397	NM_014668	GREB1	growth regulation by estrogen in breast cancer 1
chr17_-_34328530	3.374		CCL14-CCL15 CCL15	CCL14-CCL15 readthrough chemokine (C-C motif) ligand 15
chr10_+_101542460	3.282	NM_000392	ABCC2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr8_-_17743062	3.262		FGL1	fibrinogen-like 1
chr17_+_72439187	3.257		GPRC5C	G protein-coupled receptor, family C, group 5, member C
chr16_-_16317290	3.248	NM_001079528 NM_001171	ABCC6	ATP-binding cassette, sub-family C (CFTR/MRP), member 6
chr12_-_122296619	3.197	NM_002150	HPD	4-hydroxyphenylpyruvate dioxygenase
chr12_-_8043743	3.164		SLC2A14	solute carrier family 2 (facilitated glucose transporter), member 14
chr6_-_29527701	3.151	NM_006398	UBD	ubiquitin D
chr16_+_8768403	3.112	NM_020686	ABAT	4-aminobutyrate aminotransferase
chr19_+_925984	3.110	NM_005224	ARID3A	AT rich interactive domain 3A (BRIGHT-like)
chr4_-_10023094	3.088	NM_020041	SLC2A9	solute carrier family 2 (facilitated glucose transporter), member 9
chr17_+_1665342	3.084		SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr4_+_140587086	3.038		MGST2	microsomal glutathione S-transferase 2
chrX_+_115567746	2.977	NM_007231	SLC6A14	solute carrier family 6 (amino acid transporter), member 14
chr4_+_140586921	2.936	NM_001204366 NM_001204367 NM_001204368 NM_002413	MGST2	microsomal glutathione S-transferase 2
chr16_+_29471206	2.936	NM_001017390 NM_177552	SULT1A4 SULT1A3	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr7_+_137761177	2.910	NM_001190906 NM_001190907 NM_005989	AKR1D1	aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)
chr12_+_100897137	2.894	NM_001206992 NM_001206993	NR1H4	nuclear receptor subfamily 1, group H, member 4
chr14_+_39735500	2.888	NM_001247988 NM_203356	CTAGE5	CTAGE family, member 5
chr3_-_120400957	2.886		HGD	homogentisate 1,2-dioxygenase
chr17_-_26697293	2.867		VTN	vitronectin
chr14_+_74003817	2.837	NM_001037161	ACOT1	acyl-CoA thioesterase 1
chr6_+_30130982	2.799	NM_033229	TRIM15	tripartite motif containing 15
chr3_-_58522873	2.795	NM_003500	ACOX2	acyl-CoA oxidase 2, branched chain
chr2_+_42396392	2.785	NM_001145076 NM_019063	EML4	echinoderm microtubule associated protein like 4
chr19_-_51869579	2.779		ETFB	electron-transfer-flavoprotein, beta polypeptide
chr1_+_155100304	2.745	NM_004428 NM_182685	EFNA1	ephrin-A1
chr19_-_4540078	2.708		LRG1	leucine-rich alpha-2-glycoprotein 1
chr9_-_99329092	2.701	NM_001077181	CDC14B	CDC14 cell division cycle 14 homolog B (S. cerevisiae)
chr16_-_30124829	2.684	NM_024307	GDPD3	glycerophosphodiester phosphodiesterase domain containing 3
chr14_+_21156922	2.674	NM_001097577 NM_194431	ANG RNASE4	angiogenin, ribonuclease, RNase A family, 5 ribonuclease, RNase A family, 4
chr8_+_21916685	2.640	NM_001114138 NM_001978	EPB49	erythrocyte membrane protein band 4.9 (dematin)
chr22_+_21128378	2.624	NM_000185	SERPIND1	serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr3_+_133464883	2.589	NM_001063	TF	transferrin
chr15_-_79237353	2.568	NM_004390	CTSH	cathepsin H
chr19_-_41255827	2.568	NM_198476	C19orf54	chromosome 19 open reading frame 54
chr16_+_29690464	2.560		QPRT	quinolinate phosphoribosyltransferase
chr19_-_633526	2.560		POLRMT	polymerase (RNA) mitochondrial (DNA directed)
chr1_+_44064509	2.555		PTPRF	protein tyrosine phosphatase, receptor type, F
chr1_+_145727665	2.539	NM_001201325 NM_001201326 NM_002614	PDZK1	PDZ domain containing 1
chr16_+_30210548	2.533	NM_001017390 NM_177552	SULT1A4 SULT1A3	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr3_+_52812438	2.467	NM_001166434	ITIH1	inter-alpha-trypsin inhibitor heavy chain 1
chr17_-_26697310	2.376		VTN	vitronectin
chr9_-_130712866	2.355	NM_203305	FAM102A	family with sequence similarity 102, member A
chr17_+_53344966	2.341		HLF	hepatic leukemia factor
chr16_+_3115312	2.289	NM_001012631 NM_001012633 NM_001012718 NM_004221	IL32	interleukin 32
chr1_+_145727712	2.275		PDZK1	PDZ domain containing 1
chr18_-_21166440	2.274	NM_000271	NPC1	Niemann-Pick disease, type C1
chr18_-_21166378	2.239		NPC1	Niemann-Pick disease, type C1
chr17_+_41003184	2.235	NM_003734	AOC3	amine oxidase, copper containing 3 (vascular adhesion protein 1)
chr11_-_71781091	2.182		NUMA1	nuclear mitotic apparatus protein 1
chr12_-_57009361	2.178		BAZ2A	bromodomain adjacent to zinc finger domain, 2A
chr2_+_159313407	2.177		PKP4	plakophilin 4
chr19_+_45449228	2.170	NM_000483	APOC2	apolipoprotein C-II
chr19_-_55720812	2.150	NM_001161440 NM_002842	PTPRH	protein tyrosine phosphatase, receptor type, H
chrX_-_130423199	2.146		IGSF1	immunoglobulin superfamily, member 1
chr1_+_28696056	2.127	NM_001048183	PHACTR4	phosphatase and actin regulator 4
chr1_-_15911461	2.111	NM_024758	AGMAT	agmatine ureohydrolase (agmatinase)
chr17_+_1665306	2.109		SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr3_-_9921933	2.095	NM_001199551 NM_001199552	CIDEC	cell death-inducing DFFA-like effector c
chr16_-_28621279	2.063	NM_001055 NM_177529	SULT1A1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr17_+_1665281	2.058		SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr19_-_36304200	2.050	NM_021232	PRODH2	proline dehydrogenase (oxidase) 2
chr1_+_65613211	1.995	NM_203464 NM_001005353	AK4	adenylate kinase 4
chr17_+_72427535	1.989	NM_022036	GPRC5C	G protein-coupled receptor, family C, group 5, member C
chr17_+_37896219	1.987	NM_001242443	GRB7	growth factor receptor-bound protein 7
chr10_+_102729249	1.973		SEMA4G	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr11_+_61102035	1.955		DAK	dihydroxyacetone kinase 2 homolog (S. cerevisiae)
chr20_-_3149070	1.951	NM_014731	ProSAPiP1	ProSAPiP1 protein
chr16_+_29690328	1.921	NM_014298	QPRT	quinolinate phosphoribosyltransferase
chr22_-_37975937	1.896	NM_006498	LGALS2	lectin, galactoside-binding, soluble, 2
chr3_-_49459870	1.896		AMT	aminomethyltransferase
chr17_+_37894212	1.884		GRB7	growth factor receptor-bound protein 7
chr20_+_35973083	1.864	NM_005417	SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
chr2_+_219575507	1.861	NM_014640	TTLL4	tubulin tyrosine ligase-like family, member 4
chr2_+_27719702	1.859	NM_001486	GCKR	glucokinase (hexokinase 4) regulator
chr11_-_2170792	1.857	NM_001007139	IGF2	insulin-like growth factor 2 (somatomedin A)
chr7_+_149571029	1.844		ATP6V0E2	ATPase, H+ transporting V0 subunit e2
chr19_-_4342718	1.838		STAP2	signal transducing adaptor family member 2
chr3_+_142315205	1.832	NM_001145319	PLS1	plastin 1
chr3_+_38495778	1.827	NM_001106	ACVR2B	activin A receptor, type IIB
chr20_-_22566092	1.817	NM_153675	FOXA2	forkhead box A2
chr11_+_121461070	1.813		SORL1	sortilin-related receptor, L(DLR class) A repeats containing
chr19_-_36303766	1.811		PRODH2	proline dehydrogenase (oxidase) 2
chr19_+_45445494	1.796	NM_001646	APOC4-APOC2 APOC4	APOC4-APOC2 readthrough apolipoprotein C-IV
chr2_+_47596286	1.796	NM_002354	EPCAM	epithelial cell adhesion molecule
chr16_+_29912146	1.793	NM_181718	ASPHD1	aspartate beta-hydroxylase domain containing 1
chrX_+_38420690	1.789	NM_004615	TSPAN7	tetraspanin 7
chr19_+_50016490	1.788		FCGRT	Fc fragment of IgG, receptor, transporter, alpha
chr9_-_95896498	1.786	NM_004148	NINJ1	ninjurin 1
chr11_-_2160199	1.769	NM_000612	IGF2	insulin-like growth factor 2 (somatomedin A)
chr2_+_211421322	1.766	NM_001875	CPS1	carbamoyl-phosphate synthase 1, mitochondrial
chr19_+_50016500	1.739		FCGRT	Fc fragment of IgG, receptor, transporter, alpha
chr2_+_228678556	1.734	NM_001130046 NM_004591	CCL20	chemokine (C-C motif) ligand 20
chr3_-_8693723	1.725	NM_015931	C3orf32	chromosome 3 open reading frame 32
chr3_+_186330859	1.724		AHSG	alpha-2-HS-glycoprotein
chr4_-_69817478	1.707	NM_024743	UGT2A3	UDP glucuronosyltransferase 2 family, polypeptide A3
chr19_-_633563	1.705	NM_005035	POLRMT	polymerase (RNA) mitochondrial (DNA directed)
chr7_-_100882100	1.692	NM_001185080	CLDN15	claudin 15
chr3_-_9920471	1.691	NM_001199623	CIDEC	cell death-inducing DFFA-like effector c
chr7_-_95025622	1.688	NM_000940	PON3	paraoxonase 3
chr20_+_31367637	1.685	NM_175850	DNMT3B	DNA (cytosine-5-)-methyltransferase 3 beta
chr19_+_50016606	1.678		FCGRT	Fc fragment of IgG, receptor, transporter, alpha
chr16_+_72088507	1.675	NM_001126102 NM_005143	HP	haptoglobin
chr17_+_37894161	1.670	NM_005310	GRB7	growth factor receptor-bound protein 7
chr3_-_120401401	1.658	NM_000187	HGD	homogentisate 1,2-dioxygenase
chr8_+_22224758	1.656	NM_001128431 NM_001135154 NM_015359	SLC39A14	solute carrier family 39 (zinc transporter), member 14
chr12_-_48398284	1.648	NM_001844 NM_033150	COL2A1	collagen, type II, alpha 1
chr3_+_186330844	1.645	NM_001622	AHSG	alpha-2-HS-glycoprotein
chr6_-_47254143	1.639		TNFRSF21	tumor necrosis factor receptor superfamily, member 21
chr2_+_211458078	1.635	NM_001122634	CPS1	carbamoyl-phosphate synthase 1, mitochondrial
chr12_-_51419923	1.633	NM_001174129	SLC11A2	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr2_+_219646704	1.632		CYP27A1	cytochrome P450, family 27, subfamily A, polypeptide 1

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
3.30	1.76e-07	GO:0006082	organic acid metabolic process
2.91	4.02e-07	GO:0006629	lipid metabolic process
2.00	2.11e-06	GO:0042221	response to chemical stimulus
3.10	5.10e-06	GO:0019752	carboxylic acid metabolic process
3.10	5.10e-06	GO:0043436	oxoacid metabolic process
3.03	9.08e-06	GO:0042180	cellular ketone metabolic process
9.76	1.65e-05	GO:0055088	lipid homeostasis
16.46	2.00e-05	GO:0071825	protein-lipid complex subunit organization
16.46	2.00e-05	GO:0071827	plasma lipoprotein particle organization
12.18	4.62e-05	GO:0030301	cholesterol transport
25.71	5.77e-05	GO:0034377	plasma lipoprotein particle assembly
25.71	5.77e-05	GO:0065005	protein-lipid complex assembly
11.87	5.91e-05	GO:0015918	sterol transport
3.61	7.29e-05	GO:0071702	organic substance transport
6.16	7.99e-05	GO:0051346	negative regulation of hydrolase activity
18.00	8.15e-05	GO:0033344	cholesterol efflux
5.15	1.16e-04	GO:0052548	regulation of endopeptidase activity
17.14	1.20e-04	GO:0034367	macromolecular complex remodeling
17.14	1.20e-04	GO:0034368	protein-lipid complex remodeling
17.14	1.20e-04	GO:0034369	plasma lipoprotein particle remodeling
4.93	2.11e-04	GO:0052547	regulation of peptidase activity
3.91	2.74e-04	GO:0032787	monocarboxylic acid metabolic process
12.10	2.89e-04	GO:0097006	regulation of plasma lipoprotein particle levels
1.88	3.47e-04	GO:0065008	regulation of biological quality
1.99	3.99e-04	GO:0044281	small molecule metabolic process
8.04	5.24e-04	GO:0006638	neutral lipid metabolic process
8.04	5.24e-04	GO:0006639	acylglycerol metabolic process
4.19	9.07e-04	GO:0008202	steroid metabolic process
6.66	9.74e-04	GO:0010466	negative regulation of peptidase activity
16.24	1.51e-03	GO:0034381	plasma lipoprotein particle clearance
8.27	1.58e-03	GO:0010951	negative regulation of endopeptidase activity
5.61	1.97e-03	GO:0030162	regulation of proteolysis
9.57	1.99e-03	GO:0042632	cholesterol homeostasis
9.57	1.99e-03	GO:0055092	sterol homeostasis
5.11	2.12e-03	GO:0006869	lipid transport
34.28	2.75e-03	GO:0034384	high-density lipoprotein particle clearance
6.43	4.34e-03	GO:0006662	glycerol ether metabolic process
3.92	4.59e-03	GO:0032101	regulation of response to external stimulus
6.35	4.87e-03	GO:0018904	organic ether metabolic process
4.68	5.69e-03	GO:0010876	lipid localization
29.38	6.31e-03	GO:0010873	positive regulation of cholesterol esterification
6.61	1.07e-02	GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
1.56	1.23e-02	GO:0051179	localization
25.71	1.24e-02	GO:0010872	regulation of cholesterol esterification
6.43	1.36e-02	GO:0002250	adaptive immune response
15.13	1.85e-02	GO:0043691	reverse cholesterol transport
2.85	2.17e-02	GO:0006066	alcohol metabolic process
22.86	2.20e-02	GO:0033700	phospholipid efflux
2.76	2.23e-02	GO:0009308	amine metabolic process
2.53	2.55e-02	GO:0048878	chemical homeostasis
6.86	2.64e-02	GO:0006641	triglyceride metabolic process
6.86	2.64e-02	GO:0072376	protein activation cascade
1.36	2.79e-02	GO:0050896	response to stimulus
2.24	2.88e-02	GO:0042592	homeostatic process
6.53	3.79e-02	GO:0002449	lymphocyte mediated immunity
38.57	3.88e-02	GO:0010901	regulation of very-low-density lipoprotein particle remodeling
7.66	4.23e-02	GO:0061041	regulation of wound healing
7.50	4.87e-02	GO:0033993	response to lipid

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
3.10	2.78e-08	GO:0005615	extracellular space
2.58	2.20e-06	GO:0044421	extracellular region part
20.00	5.13e-06	GO:0034361	very-low-density lipoprotein particle
20.00	5.13e-06	GO:0034385	triglyceride-rich lipoprotein particle
2.10	5.36e-06	GO:0005576	extracellular region
12.86	2.57e-05	GO:0032994	protein-lipid complex
12.86	2.57e-05	GO:0034358	plasma lipoprotein particle
14.03	5.86e-04	GO:0034364	high-density lipoprotein particle
25.71	1.84e-03	GO:0034366	spherical high-density lipoprotein particle
18.70	8.30e-03	GO:0034362	low-density lipoprotein particle
18.70	8.30e-03	GO:0042627	chylomicron

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
7.74	1.68e-08	GO:0004866	endopeptidase inhibitor activity
7.60	2.24e-08	GO:0030414	peptidase inhibitor activity
7.41	3.40e-08	GO:0061135	endopeptidase regulator activity
5.10	1.06e-07	GO:0004857	enzyme inhibitor activity
6.12	7.22e-07	GO:0061134	peptidase regulator activity
7.47	8.52e-04	GO:0004867	serine-type endopeptidase inhibitor activity
7.22	3.98e-03	GO:0005319	lipid transporter activity
7.20	1.42e-02	GO:0033293	monocarboxylic acid binding
17.14	1.84e-02	GO:0015248	sterol transporter activity
30.85	2.12e-02	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity
4.73	3.60e-02	GO:0008201	heparin binding