Motif ID: HOXA9_MEIS1.p2

Z-value: 0.756


Transcription factors associated with HOXA9_MEIS1.p2:

Gene SymbolEntrez IDGene Name
HOXA9 3205 homeobox A9
MEIS1 4211 Meis homeobox 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
MEIS1chr2_+_66662516,
chr2_+_66662692
-0.572.1e-02Click!
HOXA9chr7_-_27205148-0.523.7e-02Click!


Activity profile for motif HOXA9_MEIS1.p2.

activity profile for motif HOXA9_MEIS1.p2


Sorted Z-values histogram for motif HOXA9_MEIS1.p2

Sorted Z-values for motif HOXA9_MEIS1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HOXA9_MEIS1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_-_105282714 2.428 NM_000354
SERPINA7
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr16_+_29690464 2.160 QPRT
quinolinate phosphoribosyltransferase
chr1_+_198608216 1.935 PTPRC
protein tyrosine phosphatase, receptor type, C
chr14_-_94856926 1.695 NM_001002235
NM_001002236
NM_001127700
NM_001127701
NM_001127702
NM_001127703
NM_001127704
NM_001127705
NM_001127706
NM_001127707
SERPINA1









serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1









chr15_-_58306185 1.295 NM_170697
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr16_+_29690328 1.295 NM_014298
QPRT
quinolinate phosphoribosyltransferase
chr2_+_68592317 1.128 NM_002664
PLEK
pleckstrin
chr1_+_198608244 1.038 PTPRC
protein tyrosine phosphatase, receptor type, C
chrX_-_129272014 1.015 NM_001130846
AIFM1
apoptosis-inducing factor, mitochondrion-associated, 1
chr1_+_198608136 0.967 NM_002838
NM_080921
NM_080923
PTPRC


protein tyrosine phosphatase, receptor type, C


chr1_-_169555624 0.962 F5
coagulation factor V (proaccelerin, labile factor)
chr3_-_138478184 0.883 NM_006219
PIK3CB
phosphoinositide-3-kinase, catalytic, beta polypeptide
chr1_-_169555710 0.753 NM_000130
F5
coagulation factor V (proaccelerin, labile factor)
chr4_+_88896899 0.738 SPP1
secreted phosphoprotein 1
chr18_+_2655885 0.685 NM_015295
SMCHD1
structural maintenance of chromosomes flexible hinge domain containing 1
chr12_-_51422012 0.665 NM_001174125
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr12_-_9268513 0.570 A2M
alpha-2-macroglobulin
chr2_+_68592432 0.565 PLEK
pleckstrin
chr7_+_115863004 0.559 NM_152829
TES
testis derived transcript (3 LIM domains)
chr17_-_39191100 0.545 NM_030966
KRTAP1-3
keratin associated protein 1-3

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 10 of 10 entries
Enrichment   P-value GO Accession GO Term
66.00 3.51e-02 GO:0033993 response to lipid
56.59 4.78e-02 GO:0010951 negative regulation of endopeptidase activity
40.66 3.17e-03 GO:0051346 negative regulation of hydrolase activity
29.77 8.09e-03 GO:0052548 regulation of endopeptidase activity
28.53 9.19e-03 GO:0052547 regulation of peptidase activity
17.99 2.40e-03 GO:0043086 negative regulation of catalytic activity
14.76 5.26e-03 GO:0044092 negative regulation of molecular function
14.47 5.71e-03 GO:0051336 regulation of hydrolase activity
8.39 5.55e-03 GO:0050790 regulation of catalytic activity
6.89 1.46e-02 GO:0065009 regulation of molecular function

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Showing 1 to 4 of 4 entries
Enrichment   P-value GO Accession GO Term
51.12 8.93e-03 GO:0004867 serine-type endopeptidase inhibitor activity
27.62 3.05e-02 GO:0030414 peptidase inhibitor activity
26.92 3.21e-02 GO:0061135 endopeptidase regulator activity
22.24 4.69e-02 GO:0061134 peptidase regulator activity