Motif ID: HSF1,2.p2

Z-value: 1.617


Transcription factors associated with HSF1,2.p2:

Gene SymbolEntrez IDGene Name
HSF1 3297 heat shock transcription factor 1
HSF2 3298 heat shock transcription factor 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HSF2chr6_+_122720685-0.684.1e-03Click!
HSF1chr8_+_145515244,
chr8_+_145515279
-0.312.4e-01Click!


Activity profile for motif HSF1,2.p2.

activity profile for motif HSF1,2.p2


Sorted Z-values histogram for motif HSF1,2.p2

Sorted Z-values for motif HSF1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HSF1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_224903324 7.704 NM_001136530
SERPINE2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr9_-_88715024 6.163 NM_177937
GOLM1
golgi membrane protein 1
chr11_-_119294242 4.922 NM_006288
THY1
Thy-1 cell surface antigen
chr6_+_29913400 4.556


chr7_+_134464417 4.363 CALD1
caldesmon 1
chr7_+_134464161 4.090 NM_004342
NM_033138
NM_033157
CALD1


caldesmon 1


chr16_+_70502824 3.916 FUK
fucokinase
chr14_-_52535737 3.882 NID2
nidogen 2 (osteonidogen)
chr3_-_123411185 3.789 MYLK
myosin light chain kinase
chr14_-_52535945 3.660 NM_007361
NID2
nidogen 2 (osteonidogen)
chr14_-_52535765 3.370 NID2
nidogen 2 (osteonidogen)
chr14_-_52535711 3.303 NID2
nidogen 2 (osteonidogen)
chr12_+_119616594 3.282 NM_014365
HSPB8
heat shock 22kDa protein 8
chr20_+_19870209 3.257 NM_018993
RIN2
Ras and Rab interactor 2
chr3_+_158787040 3.251 NM_001197113
NM_001197114
NM_001042705
NM_001042706
NM_001197100
IQCJ-SCHIP1

IQCJ


IQCJ-SCHIP1 readthrough

IQ motif containing J


chr6_+_151646634 3.191 NM_144497
AKAP12
A kinase (PRKA) anchor protein 12
chr2_-_106055229 3.169 NM_201557
FHL2
four and a half LIM domains 2
chr7_-_80548322 2.751 SEMA3C
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr7_-_80548666 2.646 NM_006379
SEMA3C
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr11_-_111782447 2.642 NM_001885
CRYAB
crystallin, alpha B

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 1 of 1 entries
Enrichment   P-value GO Accession GO Term
3.80 1.30e-02 GO:0009888 tissue development

Gene overrepresentation in compartment category:

Showing 1 to 6 of 6 entries
Enrichment   P-value GO Accession GO Term
22.47 3.14e-02 GO:0031594 neuromuscular junction
11.93 1.05e-03 GO:0044420 extracellular matrix part
5.93 1.83e-03 GO:0031012 extracellular matrix
5.57 2.48e-02 GO:0005578 proteinaceous extracellular matrix
3.50 1.54e-03 GO:0044421 extracellular region part
2.47 1.99e-02 GO:0005576 extracellular region

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
Enrichment   P-value GO Accession GO Term
11.46 3.53e-02 GO:0005201 extracellular matrix structural constituent
3.41 2.75e-02 GO:0042802 identical protein binding
1.48 1.75e-02 GO:0005515 protein binding