Motif ID: IKZF2.p2

Z-value: 1.712


Transcription factors associated with IKZF2.p2:

Gene SymbolEntrez IDGene Name
IKZF2 22807 IKAROS family zinc finger 2 (Helios)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
IKZF2chr2_-_214015053-0.243.7e-01Click!


Activity profile for motif IKZF2.p2.

activity profile for motif IKZF2.p2


Sorted Z-values histogram for motif IKZF2.p2

Sorted Z-values for motif IKZF2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of IKZF2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_-_38172862 6.980 NM_001135934
NM_001135935
NM_001135936
NM_006475
 POSTN



periostin, osteoblast specific factor



chr2_+_189839132 6.246 COL3A1
collagen, type III, alpha 1
chr2_+_189839113 5.701 COL3A1
collagen, type III, alpha 1
chr1_-_57045235 5.658 NM_003713
 PPAP2B
phosphatidic acid phosphatase type 2B
chr2_+_189839078 5.631 NM_000090
 COL3A1
collagen, type III, alpha 1
chr1_-_57045214 4.752 PPAP2B
phosphatidic acid phosphatase type 2B
chr2_-_238322770 4.170 COL6A3
collagen, type VI, alpha 3
chr2_-_238322840 3.902 NM_004369
NM_057164
NM_057165
NM_057166
NM_057167
 COL6A3




collagen, type VI, alpha 3




chr7_+_102553343 3.717 NM_001031692
NM_005824
 LRRC17

leucine rich repeat containing 17

chr2_-_238322815 3.350 COL6A3
collagen, type VI, alpha 3
chr7_+_94024201 3.201 COL1A2
collagen, type I, alpha 2
chr19_-_43709692 3.076 NM_002780
NM_213633
 PSG4

pregnancy specific beta-1-glycoprotein 4

chr12_-_91573264 3.051 NM_133503
 DCN
decorin
chr7_+_93551015 2.982 NM_004126
 GNG11
guanine nucleotide binding protein (G protein), gamma 11
chrX_-_135863104 2.972 ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chrX_+_135251454 2.955 NM_001159704
 FHL1
four and a half LIM domains 1
chr3_+_157154579 2.722 NM_002852
 PTX3
pentraxin 3, long
chr12_-_91576579 2.687 DCN
decorin
chr12_-_91505215 2.686 LUM
lumican
chr17_-_48262900 2.671 COL1A1
collagen, type I, alpha 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 13 of 13 entries
Enrichment   P-value GO Accession GO Term
122.22 3.66e-02 GO:0043589 skin morphogenesis
45.84 1.06e-06 GO:0030199 collagen fibril organization
31.89 2.73e-03 GO:0043588 skin development
17.07 7.81e-06 GO:0030198 extracellular matrix organization
11.12 2.23e-04 GO:0043062 extracellular structure organization
7.89 1.15e-02 GO:0007517 muscle organ development
7.74 5.79e-05 GO:0001501 skeletal system development
2.84 7.28e-04 GO:0048513 organ development
2.48 1.78e-04 GO:0048731 system development
2.23 6.70e-04 GO:0007275 multicellular organismal development
2.23 1.71e-03 GO:0048856 anatomical structure development
2.02 5.95e-03 GO:0032502 developmental process
1.74 3.56e-02 GO:0032501 multicellular organismal process

Gene overrepresentation in compartment category:

Showing 1 to 10 of 10 entries
Enrichment   P-value GO Accession GO Term
183.32 2.66e-03 GO:0005584 collagen type I
122.22 7.96e-03 GO:0005589 collagen type VI
83.33 1.67e-07 GO:0005583 fibrillar collagen
44.45 5.57e-10 GO:0005581 collagen
18.72 9.70e-09 GO:0044420 extracellular matrix part
9.74 4.84e-08 GO:0005578 proteinaceous extracellular matrix
8.68 4.38e-08 GO:0031012 extracellular matrix
4.98 8.34e-07 GO:0005615 extracellular space
4.83 2.00e-08 GO:0044421 extracellular region part
3.74 4.67e-09 GO:0005576 extracellular region

Gene overrepresentation in function category:

Showing 1 to 5 of 5 entries
Enrichment   P-value GO Accession GO Term
122.22 8.99e-03 GO:0005017 platelet-derived growth factor receptor activity
66.67 2.63e-05 GO:0048407 platelet-derived growth factor binding
26.20 1.20e-04 GO:0005518 collagen binding
16.19 1.77e-04 GO:0005201 extracellular matrix structural constituent
9.09 2.22e-02 GO:0019838 growth factor binding