ISMARA results: LEF1_TCF7

Motif ID: LEF1_TCF7_TCF7L1,2.p2

Gene Symbol	Entrez ID	Gene Name
LEF1	51176	lymphoid enhancer-binding factor 1
TCF7	6932	transcription factor 7 (T-cell specific, HMG-box)
TCF7L1	83439	transcription factor 7-like 1 (T-cell specific, HMG-box)
TCF7L2	6934	transcription factor 7-like 2 (T-cell specific, HMG-box)

Gene Symbol	Promoter	Pearson corr. coef.	P-value	Plot
TCF7L2	chr10_+_114709963	0.88	7.7e-06	Click!
LEF1	chr4_-_109087876	-0.79	2.7e-04	Click!
TCF7L1	chr2_+_85360373	0.50	4.8e-02	Click!
TCF7	chr5_+_133451297	-0.27	3.1e-01	Click!

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Showing 1 to 20 of 200 entries

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr10_+_54074037	6.489	NM_012242	DKK1	dickkopf 1 homolog (Xenopus laevis)
chr10_+_7745341	5.923		ITIH2	inter-alpha-trypsin inhibitor heavy chain 2
chr10_+_7745354	5.399		ITIH2	inter-alpha-trypsin inhibitor heavy chain 2
chr10_+_7745325	5.248		ITIH2	inter-alpha-trypsin inhibitor heavy chain 2
chr6_-_128841432	4.878	NM_002844 NM_001135648	PTPRK	protein tyrosine phosphatase, receptor type, K
chr11_+_69455837	4.580	NM_053056	CCND1	cyclin D1
chr14_-_65409445	4.556	NM_002083	GPX2	glutathione peroxidase 2 (gastrointestinal)
chr4_+_39063851	4.292	NM_015990 NM_199039	KLHL5	kelch-like 5 (Drosophila)
chr11_+_69455938	4.261		CCND1	cyclin D1
chr10_+_7745229	4.164	NM_002216	ITIH2	inter-alpha-trypsin inhibitor heavy chain 2
chr18_-_25757351	4.035	NM_001792	CDH2	cadherin 2, type 1, N-cadherin (neuronal)
chr4_-_186877413	3.963		SORBS2	sorbin and SH3 domain containing 2
chr5_-_16936371	3.818	NM_012334	MYO10	myosin X
chr1_-_225840660	3.818	NM_001008493 NM_018212	ENAH	enabled homolog (Drosophila)
chr10_+_7745284	3.803		ITIH2	inter-alpha-trypsin inhibitor heavy chain 2
chrX_-_105282714	3.639	NM_000354	SERPINA7	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr7_-_107643330	3.591	NM_002291	LAMB1	laminin, beta 1
chr12_-_122296619	3.259	NM_002150	HPD	4-hydroxyphenylpyruvate dioxygenase
chr5_-_16738346	3.192		MYO10	myosin X
chr4_-_157892545	3.186	NM_016205	PDGFC	platelet derived growth factor C

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Showing 1 to 7 of 7 entries

Enrichment	P-value	GO Accession	GO Term
16.17	7.32e-03	GO:0090090	negative regulation of canonical Wnt receptor signaling pathway
12.46	4.49e-03	GO:0030178	negative regulation of Wnt receptor signaling pathway
12.42	2.70e-02	GO:0010951	negative regulation of endopeptidase activity
8.86	7.49e-03	GO:0030162	regulation of proteolysis
6.96	1.04e-02	GO:0052548	regulation of endopeptidase activity
6.67	1.42e-02	GO:0052547	regulation of peptidase activity
4.09	1.87e-02	GO:0048585	negative regulation of response to stimulus

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Showing 1 to 4 of 4 entries

Enrichment	P-value	GO Accession	GO Term
7.38	5.22e-03	GO:0005912	adherens junction
6.63	1.03e-02	GO:0070161	anchoring junction
3.56	4.91e-04	GO:0005615	extracellular space
3.00	2.66e-03	GO:0044421	extracellular region part

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Showing 1 to 10 of 10 entries

Enrichment	P-value	GO Accession	GO Term
69.51	3.48e-02	GO:0070053	thrombospondin receptor activity
41.71	4.74e-03	GO:0045295	gamma-catenin binding
13.46	5.88e-04	GO:0004867	serine-type endopeptidase inhibitor activity
9.85	1.62e-04	GO:0004866	endopeptidase inhibitor activity
9.68	1.85e-04	GO:0030414	peptidase inhibitor activity
9.43	2.25e-04	GO:0061135	endopeptidase regulator activity
7.79	9.47e-04	GO:0061134	peptidase regulator activity
5.65	3.38e-03	GO:0004857	enzyme inhibitor activity
3.46	3.63e-02	GO:0008092	cytoskeletal protein binding
2.86	2.33e-02	GO:0030234	enzyme regulator activity