Motif ID: MYFfamily.p2

Z-value: 3.120


Transcription factors associated with MYFfamily.p2:

Gene SymbolEntrez IDGene Name
MYF5 4617 myogenic factor 5
MYF6 4618 myogenic factor 6 (herculin)
MYOD1 4654 myogenic differentiation 1
MYOG 4656 myogenin (myogenic factor 4)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
MYOD1chr11_+_177411090.243.6e-01Click!
MYF6chr12_+_811014070.107.2e-01Click!
MYF5chr12_+_811106890.087.7e-01Click!
MYOGchr1_-_203055088,
chr1_-_203055376
0.048.7e-01Click!


Activity profile for motif MYFfamily.p2.

activity profile for motif MYFfamily.p2


Sorted Z-values histogram for motif MYFfamily.p2

Sorted Z-values for motif MYFfamily.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MYFfamily.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_76424474 10.371 PHLDA1
pleckstrin homology-like domain, family A, member 1
chr12_-_76425207 10.204 PHLDA1
pleckstrin homology-like domain, family A, member 1
chr3_-_32022734 10.153 OSBPL10
oxysterol binding protein-like 10
chr4_-_57976516 9.101 IGFBP7
insulin-like growth factor binding protein 7
chr4_-_57976550 8.809 NM_001253835
NM_001553
IGFBP7

insulin-like growth factor binding protein 7

chr12_-_76425375 8.277 NM_007350
PHLDA1
pleckstrin homology-like domain, family A, member 1
chr4_-_57976355 7.593 IGFBP7
insulin-like growth factor binding protein 7
chr12_-_106641675 7.168 NM_006825
CKAP4
cytoskeleton-associated protein 4
chr1_-_57045214 6.593 PPAP2B
phosphatidic acid phosphatase type 2B
chr2_-_227664330 6.127 IRS1
insulin receptor substrate 1
chr16_-_74640997 5.938 GLG1
golgi glycoprotein 1
chr2_+_36583369 5.622 NM_016441
CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr2_-_161350304 5.551 NM_002897
NM_016836
RBMS1

RNA binding motif, single stranded interacting protein 1

chr16_-_74640915 5.535 GLG1
golgi glycoprotein 1
chr12_-_89745997 5.522 DUSP6
dual specificity phosphatase 6
chr1_-_57045129 5.505 PPAP2B
phosphatidic acid phosphatase type 2B
chr10_+_124220990 5.305 NM_002775
HTRA1
HtrA serine peptidase 1
chr1_-_57045235 5.177 NM_003713
PPAP2B
phosphatidic acid phosphatase type 2B
chr6_+_107811272 4.997 NM_018013
SOBP
sine oculis binding protein homolog (Drosophila)
chr1_-_57044980 4.888 PPAP2B
phosphatidic acid phosphatase type 2B
chr3_-_124774735 4.824 NM_020733
HEG1
HEG homolog 1 (zebrafish)
chrX_-_38079980 4.745 NM_001170750
NM_001170751
NM_001170752
NM_006307
SRPX



sushi-repeat containing protein, X-linked



chr2_-_160654736 3.997 NM_001198763
NM_001198764
NM_014880
CD302


CD302 molecule


chr2_-_160654668 3.811 CD302
CD302 molecule
chr3_-_49395697 3.704 GPX1
glutathione peroxidase 1
chr8_-_62627111 3.553 ASPH
aspartate beta-hydroxylase
chr2_-_161349874 3.540 RBMS1
RNA binding motif, single stranded interacting protein 1
chr3_-_49395751 3.509 NM_000581
NM_201397
GPX1

glutathione peroxidase 1

chr1_-_59248287 3.487 JUN
jun proto-oncogene
chr14_-_52535737 3.487 NID2
nidogen 2 (osteonidogen)
chr3_-_145878775 3.476 PLOD2
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr3_-_145878936 3.455 PLOD2
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr10_+_89419352 3.435 NM_001015880
NM_004670
PAPSS2

3'-phosphoadenosine 5'-phosphosulfate synthase 2

chr2_-_56150862 3.420 EFEMP1
EGF containing fibulin-like extracellular matrix protein 1
chr8_+_37654757 3.385 GPR124
G protein-coupled receptor 124
chr16_-_74641014 3.347 NM_001145666
NM_001145667
NM_012201
GLG1


golgi glycoprotein 1


chr11_+_32112414 3.264 NM_002901
RCN1
reticulocalbin 1, EF-hand calcium binding domain
chr13_-_114567011 3.247 GAS6
growth arrest-specific 6
chr6_+_114178516 3.235 NM_002356
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr8_+_56015013 3.134 NM_052898
XKR4
XK, Kell blood group complex subunit-related family, member 4
chr4_+_169753105 3.126 NM_001166110
PALLD
palladin, cytoskeletal associated protein
chr11_-_12030128 3.065 NM_001018057
DKK3
dickkopf 3 homolog (Xenopus laevis)
chrX_-_154688260 2.993 NM_001007523
NM_001007524
NM_012151
F8A2
F8A3
F8A1
coagulation factor VIII-associated 2
coagulation factor VIII-associated 3
coagulation factor VIII-associated 1
chr20_-_23066828 2.973 NM_012072
CD93
CD93 molecule
chr5_+_140864626 2.967 NM_018928
NM_032406
PCDHGC4

protocadherin gamma subfamily C, 4

chr1_-_59042827 2.963 TACSTD2
tumor-associated calcium signal transducer 2
chr9_-_84304378 2.932 TLE1
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr13_-_114567040 2.897 NM_000820
GAS6
growth arrest-specific 6
chr8_+_31497267 2.859 NM_013962
NRG1
neuregulin 1
chr13_-_114567034 2.842 GAS6
growth arrest-specific 6
chr8_+_37654833 2.805 GPR124
G protein-coupled receptor 124
chr4_-_102267952 2.766 PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr13_-_114566951 2.756 GAS6
growth arrest-specific 6
chr3_-_79068542 2.750 NM_001145845
NM_133631
ROBO1

roundabout, axon guidance receptor, homolog 1 (Drosophila)

chr14_-_75078669 2.746 NM_000428
LTBP2
latent transforming growth factor beta binding protein 2
chr19_+_3094528 2.738 GNA11
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
chr18_+_61637262 2.736 NM_001031848
NM_002640
NM_198833
SERPINB8


serpin peptidase inhibitor, clade B (ovalbumin), member 8


chr11_+_69455938 2.684 CCND1
cyclin D1
chr12_-_49319211 2.623 NM_001143782
NM_016594
FKBP11

FK506 binding protein 11, 19 kDa

chr2_-_56151273 2.591 NM_001039348
NM_001039349
EFEMP1

EGF containing fibulin-like extracellular matrix protein 1

chr9_-_139940556 2.556 NPDC1
neural proliferation, differentiation and control, 1
chr6_-_31239888 2.539 NM_001243042
NM_002117
HLA-C

major histocompatibility complex, class I, C

chr2_+_217498205 2.537 IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr2_+_217498082 2.483 NM_000597
IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr1_+_25071906 2.444 CLIC4
chloride intracellular channel 4
chr2_+_191745791 2.436 GLS
glutaminase
chr1_+_64058891 2.403 NM_002633
PGM1
phosphoglucomutase 1
chr22_+_33197678 2.368 TIMP3
TIMP metallopeptidase inhibitor 3
chr10_+_54074037 2.366 NM_012242
DKK1
dickkopf 1 homolog (Xenopus laevis)
chr2_-_190044330 2.342 NM_000393
COL5A2
collagen, type V, alpha 2
chr6_+_151646634 2.336 NM_144497
AKAP12
A kinase (PRKA) anchor protein 12
chr2_-_227663454 2.330 NM_005544
IRS1
insulin receptor substrate 1
chr2_+_173292344 2.280 ITGA6
integrin, alpha 6
chr3_+_110790460 2.271 NM_001243286
NM_015480
PVRL3

poliovirus receptor-related 3

chr12_-_54813002 2.262 ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr10_+_120967094 2.255 NM_005308
GRK5
G protein-coupled receptor kinase 5
chr4_-_102268333 2.240 PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr9_+_133320093 2.239 NM_000050
NM_054012
ASS1

argininosuccinate synthase 1

chr13_+_36050885 2.146 NM_001204197
NBEA
neurobeachin
chr18_-_25756946 2.145 CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr8_+_37654406 2.119 GPR124
G protein-coupled receptor 124
chr1_+_25071759 2.116 NM_013943
CLIC4
chloride intracellular channel 4
chr8_-_23712297 2.085 NM_003155
STC1
stanniocalcin 1
chr2_-_216300770 2.071 NM_002026
NM_054034
NM_212474
NM_212476
NM_212478
NM_212482
FN1





fibronectin 1





chr19_-_19051112 2.067 NM_001145722
NM_001145721
HOMER3

homer homolog 3 (Drosophila)

chr13_-_110438896 2.053 NM_003749
IRS2
insulin receptor substrate 2
chrX_-_140271275 2.046 LDOC1
leucine zipper, down-regulated in cancer 1
chr12_-_7261788 2.040 NM_016546
C1RL
complement component 1, r subcomponent-like
chr2_+_173292306 2.040 NM_000210
NM_001079818
ITGA6

integrin, alpha 6

chr9_+_116263706 2.026 NM_130795
RGS3
regulator of G-protein signaling 3
chr1_+_180123906 2.019 NM_001004128
NM_002826
QSOX1

quiescin Q6 sulfhydryl oxidase 1

chr12_-_6665220 2.017 NM_001039670
NM_001193457
NM_080730
IFFO1


intermediate filament family orphan 1


chr19_+_3094266 2.014 NM_002067
GNA11
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
chr3_-_99833348 2.005 NM_001042459
NM_182909
FILIP1L

filamin A interacting protein 1-like

chr15_+_96873845 1.995 NM_021005
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr9_-_139940464 1.978 NPDC1
neural proliferation, differentiation and control, 1
chr12_+_53491417 1.973 NM_002178
IGFBP6
insulin-like growth factor binding protein 6
chr18_-_25757351 1.963 NM_001792
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr6_-_132272311 1.955 NM_001901
CTGF
connective tissue growth factor
chr12_-_54813010 1.955 NM_002205
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr22_-_36681757 1.953 MYH9
myosin, heavy chain 9, non-muscle
chr13_+_110959592 1.952 NM_001846
COL4A2
collagen, type IV, alpha 2
chr1_+_64059479 1.941 NM_001172819
PGM1
phosphoglucomutase 1
chr6_-_31239489 1.940 HLA-B
HLA-C
major histocompatibility complex, class I, B
major histocompatibility complex, class I, C
chr1_+_25071967 1.938 CLIC4
chloride intracellular channel 4
chr5_+_92920592 1.929 NR2F1
NR2F2
nuclear receptor subfamily 2, group F, member 1
nuclear receptor subfamily 2, group F, member 2
chr11_-_117166247 1.923 NM_001207048
NM_001207049
BACE1

beta-site APP-cleaving enzyme 1

chr19_-_44174271 1.917 PLAUR
plasminogen activator, urokinase receptor
chr18_+_56530677 1.902 ZNF532
zinc finger protein 532
chr12_-_54812936 1.900 ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr13_-_72440557 1.896 DACH1
dachshund homolog 1 (Drosophila)
chr8_+_17433941 1.883 NM_006207
PDGFRL
platelet-derived growth factor receptor-like
chr2_+_191745568 1.874 GLS
glutaminase
chr21_+_42540092 1.867 BACE2
beta-site APP-cleaving enzyme 2
chr9_+_133320247 1.867 ASS1
argininosuccinate synthase 1
chr7_+_100199881 1.846 NM_002593
PCOLCE
procollagen C-endopeptidase enhancer
chrX_-_140271293 1.846 NM_012317
LDOC1
leucine zipper, down-regulated in cancer 1
chr8_-_62626929 1.841 ASPH
aspartate beta-hydroxylase
chr7_+_32996961 1.840 NM_007270
FKBP9
FK506 binding protein 9, 63 kDa
chr20_-_23618382 1.827 NM_000099
CST3
cystatin C
chr22_-_36783851 1.824 MYH9
myosin, heavy chain 9, non-muscle
chr11_-_6341708 1.821 NM_145040
PRKCDBP
protein kinase C, delta binding protein
chr2_-_20212408 1.814 MATN3
matrilin 3
chr11_+_32112607 1.813 RCN1
reticulocalbin 1, EF-hand calcium binding domain
chr6_+_43043944 1.807 NM_002821
NM_152880
NM_152881
NM_152882
PTK7



PTK7 protein tyrosine kinase 7



chr6_+_7541863 1.794 NM_001008844
NM_004415
DSP

desmoplakin

chr7_-_45960738 1.788 NM_000598
NM_001013398
IGFBP3

insulin-like growth factor binding protein 3

chr1_-_85930610 1.777 DDAH1
dimethylarginine dimethylaminohydrolase 1
chr15_+_99191671 1.775 IGF1R
insulin-like growth factor 1 receptor
chr2_+_71295407 1.772 NM_017567
NAGK
N-acetylglucosamine kinase
chr5_+_52284903 1.765 NM_002203
ITGA2
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
chr3_-_145879222 1.729 NM_000935
NM_182943
PLOD2

procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2

chr10_-_15413054 1.722 NM_001010924
FAM171A1
family with sequence similarity 171, member A1
chr9_-_139940595 1.718 NM_015392
NPDC1
neural proliferation, differentiation and control, 1
chr17_+_38599651 1.711 NM_001552
IGFBP4
insulin-like growth factor binding protein 4
chr12_+_53491448 1.702 IGFBP6
insulin-like growth factor binding protein 6
chr20_+_3451615 1.692 NM_001207047
NM_139321
NM_139322
ATRN


attractin


chr1_-_85930733 1.687 NM_012137
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr13_-_110959441 1.676 NM_001845
COL4A1
collagen, type IV, alpha 1
chr6_+_7727010 1.664 NM_001718
BMP6
bone morphogenetic protein 6
chr8_+_37654395 1.649 NM_032777
GPR124
G protein-coupled receptor 124
chr2_+_191745546 1.619 NM_014905
GLS
glutaminase
chr1_+_90286595 1.611 LRRC8D
leucine rich repeat containing 8 family, member D
chr3_-_149688886 1.598 PFN2
profilin 2
chr14_-_94856926 1.593 NM_001002235
NM_001002236
NM_001127700
NM_001127701
NM_001127702
NM_001127703
NM_001127704
NM_001127705
NM_001127706
NM_001127707
SERPINA1









serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1









chr12_+_66218879 1.586 HMGA2
high mobility group AT-hook 2
chr3_-_189838907 1.584 NM_018192
LEPREL1
leprecan-like 1
chr14_-_74960035 1.571 NM_006432
NPC2
Niemann-Pick disease, type C2
chr21_-_28217272 1.569 ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr14_-_74960003 1.568 NPC2
Niemann-Pick disease, type C2
chrX_+_154611748 1.562 NM_001007523
NM_001007524
NM_012151
F8A2
F8A3
F8A1
coagulation factor VIII-associated 2
coagulation factor VIII-associated 3
coagulation factor VIII-associated 1
chr5_+_86564146 1.560 RASA1
RAS p21 protein activator (GTPase activating protein) 1
chr1_-_94703252 1.545 NM_004815
ARHGAP29
Rho GTPase activating protein 29
chr11_-_86666211 1.531 NM_012193
FZD4
frizzled family receptor 4
chr2_+_20646831 1.522 NM_004040
RHOB
ras homolog gene family, member B
chr9_+_114393543 1.521 NM_001015882
NM_004125
DNAJC25
DNAJC25-GNG10
DnaJ (Hsp40) homolog, subfamily C , member 25
DNAJC25-GNG10 readthrough
chr6_+_7541892 1.517 DSP
desmoplakin
chr14_-_74959976 1.512 NPC2
Niemann-Pick disease, type C2
chr5_-_178772328 1.509 ADAMTS2
ADAM metallopeptidase with thrombospondin type 1 motif, 2
chr4_+_15704572 1.508 NM_004334
BST1
bone marrow stromal cell antigen 1
chr8_-_62627167 1.499 NM_001164754
NM_001164755
NM_001164756
NM_004318
NM_032466
ASPH




aspartate beta-hydroxylase




chr22_+_33197744 1.499 TIMP3
TIMP metallopeptidase inhibitor 3
chr3_-_149688638 1.484 NM_002628
NM_053024
PFN2

profilin 2

chr5_+_52776479 1.478 FST
follistatin
chr4_-_102268626 1.477 NM_000944
NM_001130691
NM_001130692
PPP3CA


protein phosphatase 3, catalytic subunit, alpha isozyme


chr14_+_65007163 1.471 NM_021979
HSPA2
heat shock 70kDa protein 2
chr9_+_124030455 1.467 GSN
gelsolin
chr4_-_5021095 1.467 NM_018659
CYTL1
cytokine-like 1
chr9_-_14313899 1.466 NFIB
nuclear factor I/B
chr3_-_187463474 1.466 NM_001706
BCL6
B-cell CLL/lymphoma 6
chr14_-_52535765 1.440 NID2
nidogen 2 (osteonidogen)
chr11_-_102668892 1.434 NM_001145938
NM_002421
MMP1

matrix metallopeptidase 1 (interstitial collagenase)

chr5_+_52776408 1.432 FST
follistatin
chr1_-_98386594 1.427 NM_000110
NM_001160301
DPYD

dihydropyrimidine dehydrogenase

chr11_-_102668822 1.424 MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr1_+_86046434 1.423 NM_001554
CYR61
cysteine-rich, angiogenic inducer, 61
chr20_+_44520203 1.419 CTSA
cathepsin A
chr17_+_28705960 1.409 CPD
carboxypeptidase D
chr20_+_44520021 1.407 CTSA
cathepsin A
chr12_+_49208615 1.404 CACNB3
calcium channel, voltage-dependent, beta 3 subunit
chr11_-_12030539 1.396 DKK3
dickkopf 3 homolog (Xenopus laevis)
chr19_-_44174497 1.394 NM_001005376
NM_001005377
NM_002659
PLAUR


plasminogen activator, urokinase receptor


chr3_-_158390266 1.393 NM_020169
LXN
latexin
chrX_+_154114609 1.390 NM_001007523
NM_001007524
NM_012151
F8A2
F8A3
F8A1
coagulation factor VIII-associated 2
coagulation factor VIII-associated 3
coagulation factor VIII-associated 1
chr11_-_66115016 1.385 NM_006876
B3GNT1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
chr16_+_56659584 1.373 NM_175617
MT1E
metallothionein 1E
chr7_-_131241321 1.373 NM_001018111
NM_005397
PODXL

podocalyxin-like

chr3_+_105085553 1.371 NM_001243280
NM_001243281
NM_001243283
NM_001627
ALCAM



activated leukocyte cell adhesion molecule



chr19_+_16187315 1.357 TPM4
tropomyosin 4
chr14_-_54423448 1.328 NM_001202
NM_130850
BMP4

bone morphogenetic protein 4

chr19_+_45349560 1.326 PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr14_-_52535945 1.320 NM_007361
NID2
nidogen 2 (osteonidogen)
chr13_-_72440143 1.318 DACH1
dachshund homolog 1 (Drosophila)
chr16_+_56659679 1.318 MT1E
metallothionein 1E
chr12_+_49208214 1.316 NM_001206917
CACNB3
calcium channel, voltage-dependent, beta 3 subunit
chr13_+_113951461 1.310 NM_005561
LAMP1
lysosomal-associated membrane protein 1
chr1_-_225840660 1.305 NM_001008493
NM_018212
ENAH

enabled homolog (Drosophila)

chr9_-_130616760 1.300 ENG
endoglin
chr1_-_156647088 1.276 NM_006617
NES
nestin
chr8_+_94929991 1.276 NM_001161778
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
6.96 2.70e-09 GO:0048514 blood vessel morphogenesis
2.80 3.38e-09 GO:0009653 anatomical structure morphogenesis
3.50 4.38e-09 GO:0040011 locomotion
6.00 1.56e-08 GO:0001568 blood vessel development
4.48 2.65e-08 GO:0072358 cardiovascular system development
4.48 2.65e-08 GO:0072359 circulatory system development
5.59 6.29e-08 GO:0001944 vasculature development
1.89 7.53e-08 GO:0032502 developmental process
2.00 1.00e-07 GO:0048856 anatomical structure development
2.04 2.86e-07 GO:0048731 system development
1.91 4.15e-07 GO:0007275 multicellular organismal development
1.68 7.25e-07 GO:0032501 multicellular organismal process
3.22 1.25e-06 GO:0009888 tissue development
3.01 2.33e-06 GO:0009611 response to wounding
2.06 1.02e-05 GO:0042221 response to chemical stimulus
6.50 1.10e-05 GO:0001525 angiogenesis
3.99 1.71e-05 GO:0048646 anatomical structure formation involved in morphogenesis
2.16 2.09e-05 GO:0048869 cellular developmental process
1.52 3.31e-05 GO:0050896 response to stimulus
2.13 6.11e-05 GO:0030154 cell differentiation
3.46 6.36e-05 GO:0006928 cellular component movement
3.27 1.04e-04 GO:0042060 wound healing
3.78 1.92e-04 GO:0016477 cell migration
2.98 2.34e-04 GO:0007155 cell adhesion
2.98 2.34e-04 GO:0022610 biological adhesion
2.57 5.34e-04 GO:0009605 response to external stimulus
2.77 6.35e-04 GO:0051128 regulation of cellular component organization
3.51 6.56e-04 GO:0048870 cell motility
3.51 6.56e-04 GO:0051674 localization of cell
7.36 1.13e-03 GO:0030198 extracellular matrix organization
5.75 1.34e-03 GO:0043062 extracellular structure organization
3.02 1.45e-03 GO:0032989 cellular component morphogenesis
4.08 2.26e-03 GO:0040012 regulation of locomotion
2.55 3.45e-03 GO:0048468 cell development
1.66 3.46e-03 GO:0007165 signal transduction
1.89 3.62e-03 GO:0048523 negative regulation of cellular process
1.97 4.47e-03 GO:0048583 regulation of response to stimulus
5.13 4.50e-03 GO:0030155 regulation of cell adhesion
1.83 4.69e-03 GO:0048519 negative regulation of biological process
1.96 5.17e-03 GO:0048513 organ development
3.42 6.29e-03 GO:0009968 negative regulation of signal transduction
2.92 7.23e-03 GO:0000902 cell morphogenesis
3.11 7.77e-03 GO:0000904 cell morphogenesis involved in differentiation
3.10 8.35e-03 GO:0048585 negative regulation of response to stimulus
3.86 9.54e-03 GO:0016337 cell-cell adhesion
2.08 1.12e-02 GO:0007399 nervous system development
7.56 1.17e-02 GO:0045785 positive regulation of cell adhesion
3.77 1.28e-02 GO:0051270 regulation of cellular component movement
1.53 1.38e-02 GO:0051716 cellular response to stimulus
1.92 1.46e-02 GO:0007166 cell surface receptor linked signaling pathway
3.18 1.76e-02 GO:0023057 negative regulation of signaling
2.94 1.80e-02 GO:0006935 chemotaxis
2.94 1.80e-02 GO:0042330 taxis
3.47 1.82e-02 GO:0060429 epithelium development
3.87 1.88e-02 GO:0030334 regulation of cell migration
3.16 1.90e-02 GO:0010648 negative regulation of cell communication
3.84 2.07e-02 GO:2000145 regulation of cell motility
4.77 2.32e-02 GO:0030855 epithelial cell differentiation
6.75 2.73e-02 GO:0030879 mammary gland development
8.05 2.82e-02 GO:0007229 integrin-mediated signaling pathway
3.14 3.57e-02 GO:0040008 regulation of growth
4.44 4.57e-02 GO:0010038 response to metal ion
3.56 4.77e-02 GO:0010035 response to inorganic substance
2.84 4.82e-02 GO:0007596 blood coagulation
2.84 4.82e-02 GO:0050817 coagulation

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
3.78 1.19e-14 GO:0044421 extracellular region part
2.80 1.02e-12 GO:0005576 extracellular region
5.99 3.19e-12 GO:0031012 extracellular matrix
3.62 5.04e-10 GO:0005615 extracellular space
5.17 3.12e-07 GO:0005578 proteinaceous extracellular matrix
9.73 2.56e-04 GO:0031983 vesicle lumen
8.73 6.01e-04 GO:0005604 basement membrane
3.31 2.75e-03 GO:0009986 cell surface
5.81 4.36e-03 GO:0044420 extracellular matrix part
11.72 1.06e-02 GO:0001725 stress fiber
3.42 1.13e-02 GO:0015629 actin cytoskeleton
11.30 1.27e-02 GO:0008305 integrin complex
10.91 1.52e-02 GO:0032432 actin filament bundle
8.08 1.67e-02 GO:0031093 platelet alpha granule lumen
7.91 1.89e-02 GO:0034774 secretory granule lumen
7.59 2.38e-02 GO:0060205 cytoplasmic membrane-bounded vesicle lumen
9.89 2.48e-02 GO:0042641 actomyosin
4.32 4.45e-02 GO:0005912 adherens junction
6.78 4.50e-02 GO:0031091 platelet alpha granule

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
34.79 3.84e-13 GO:0005520 insulin-like growth factor binding
9.40 1.11e-08 GO:0019838 growth factor binding
4.25 1.16e-04 GO:0032403 protein complex binding
42.16 2.07e-04 GO:0031994 insulin-like growth factor I binding
1.33 1.17e-03 GO:0005515 protein binding
7.45 2.53e-03 GO:0005201 extracellular matrix structural constituent
5.05 2.62e-03 GO:0001871 pattern binding
5.05 2.62e-03 GO:0030247 polysaccharide binding
47.44 3.61e-03 GO:0005010 insulin-like growth factor receptor activity
47.44 3.61e-03 GO:0031995 insulin-like growth factor II binding
3.36 5.31e-03 GO:0030246 carbohydrate binding
5.81 5.45e-03 GO:0008201 heparin binding
6.66 5.80e-03 GO:0019199 transmembrane receptor protein kinase activity
4.95 7.89e-03 GO:0005539 glycosaminoglycan binding
7.51 8.66e-03 GO:0004714 transmembrane receptor protein tyrosine kinase activity
9.04 4.81e-02 GO:0005518 collagen binding