Motif ID: MYFfamily.p2

Z-value: 3.120


Transcription factors associated with MYFfamily.p2:

Gene SymbolEntrez IDGene Name
MYF5 4617 myogenic factor 5
MYF6 4618 myogenic factor 6 (herculin)
MYOD1 4654 myogenic differentiation 1
MYOG 4656 myogenin (myogenic factor 4)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
MYOD1chr11_+_177411090.243.6e-01Click!
MYF6chr12_+_811014070.107.2e-01Click!
MYF5chr12_+_811106890.087.7e-01Click!
MYOGchr1_-_203055088,
chr1_-_203055376		0.048.7e-01Click!


Activity profile for motif MYFfamily.p2.

activity profile for motif MYFfamily.p2


Sorted Z-values histogram for motif MYFfamily.p2

Sorted Z-values for motif MYFfamily.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MYFfamily.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_76424474 10.371 PHLDA1
pleckstrin homology-like domain, family A, member 1
chr12_-_76425207 10.204 PHLDA1
pleckstrin homology-like domain, family A, member 1
chr3_-_32022734 10.153 OSBPL10
oxysterol binding protein-like 10
chr4_-_57976516 9.101 IGFBP7
insulin-like growth factor binding protein 7
chr4_-_57976550 8.809 NM_001253835
NM_001553
 IGFBP7

insulin-like growth factor binding protein 7

chr12_-_76425375 8.277 NM_007350
 PHLDA1
pleckstrin homology-like domain, family A, member 1
chr4_-_57976355 7.593 IGFBP7
insulin-like growth factor binding protein 7
chr12_-_106641675 7.168 NM_006825
 CKAP4
cytoskeleton-associated protein 4
chr1_-_57045214 6.593 PPAP2B
phosphatidic acid phosphatase type 2B
chr2_-_227664330 6.127 IRS1
insulin receptor substrate 1
chr16_-_74640997 5.938 GLG1
golgi glycoprotein 1
chr2_+_36583369 5.622 NM_016441
 CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr2_-_161350304 5.551 NM_002897
NM_016836
 RBMS1

RNA binding motif, single stranded interacting protein 1

chr16_-_74640915 5.535 GLG1
golgi glycoprotein 1
chr12_-_89745997 5.522 DUSP6
dual specificity phosphatase 6
chr1_-_57045129 5.505 PPAP2B
phosphatidic acid phosphatase type 2B
chr10_+_124220990 5.305 NM_002775
 HTRA1
HtrA serine peptidase 1
chr1_-_57045235 5.177 NM_003713
 PPAP2B
phosphatidic acid phosphatase type 2B
chr6_+_107811272 4.997 NM_018013
 SOBP
sine oculis binding protein homolog (Drosophila)
chr1_-_57044980 4.888 PPAP2B
phosphatidic acid phosphatase type 2B

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 65 entries
Enrichment   P-value GO Accession GO Term
8.05 2.82e-02 GO:0007229 integrin-mediated signaling pathway
7.56 1.17e-02 GO:0045785 positive regulation of cell adhesion
7.36 1.13e-03 GO:0030198 extracellular matrix organization
6.96 2.70e-09 GO:0048514 blood vessel morphogenesis
6.75 2.73e-02 GO:0030879 mammary gland development
6.50 1.10e-05 GO:0001525 angiogenesis
6.00 1.56e-08 GO:0001568 blood vessel development
5.75 1.34e-03 GO:0043062 extracellular structure organization
5.59 6.29e-08 GO:0001944 vasculature development
5.13 4.50e-03 GO:0030155 regulation of cell adhesion
4.77 2.32e-02 GO:0030855 epithelial cell differentiation
4.48 2.65e-08 GO:0072358 cardiovascular system development
4.48 2.65e-08 GO:0072359 circulatory system development
4.44 4.57e-02 GO:0010038 response to metal ion
4.08 2.26e-03 GO:0040012 regulation of locomotion
3.99 1.71e-05 GO:0048646 anatomical structure formation involved in morphogenesis
3.87 1.88e-02 GO:0030334 regulation of cell migration
3.86 9.54e-03 GO:0016337 cell-cell adhesion
3.84 2.07e-02 GO:2000145 regulation of cell motility
3.78 1.92e-04 GO:0016477 cell migration

Gene overrepresentation in compartment category:

Showing 1 to 19 of 19 entries
Enrichment   P-value GO Accession GO Term
11.72 1.06e-02 GO:0001725 stress fiber
11.30 1.27e-02 GO:0008305 integrin complex
10.91 1.52e-02 GO:0032432 actin filament bundle
9.89 2.48e-02 GO:0042641 actomyosin
9.73 2.56e-04 GO:0031983 vesicle lumen
8.73 6.01e-04 GO:0005604 basement membrane
8.08 1.67e-02 GO:0031093 platelet alpha granule lumen
7.91 1.89e-02 GO:0034774 secretory granule lumen
7.59 2.38e-02 GO:0060205 cytoplasmic membrane-bounded vesicle lumen
6.78 4.50e-02 GO:0031091 platelet alpha granule
5.99 3.19e-12 GO:0031012 extracellular matrix
5.81 4.36e-03 GO:0044420 extracellular matrix part
5.17 3.12e-07 GO:0005578 proteinaceous extracellular matrix
4.32 4.45e-02 GO:0005912 adherens junction
3.78 1.19e-14 GO:0044421 extracellular region part
3.62 5.04e-10 GO:0005615 extracellular space
3.42 1.13e-02 GO:0015629 actin cytoskeleton
3.31 2.75e-03 GO:0009986 cell surface
2.80 1.02e-12 GO:0005576 extracellular region

Gene overrepresentation in function category:

Showing 1 to 16 of 16 entries
Enrichment   P-value GO Accession GO Term
47.44 3.61e-03 GO:0005010 insulin-like growth factor receptor activity
47.44 3.61e-03 GO:0031995 insulin-like growth factor II binding
42.16 2.07e-04 GO:0031994 insulin-like growth factor I binding
34.79 3.84e-13 GO:0005520 insulin-like growth factor binding
9.40 1.11e-08 GO:0019838 growth factor binding
9.04 4.81e-02 GO:0005518 collagen binding
7.51 8.66e-03 GO:0004714 transmembrane receptor protein tyrosine kinase activity
7.45 2.53e-03 GO:0005201 extracellular matrix structural constituent
6.66 5.80e-03 GO:0019199 transmembrane receptor protein kinase activity
5.81 5.45e-03 GO:0008201 heparin binding
5.05 2.62e-03 GO:0001871 pattern binding
5.05 2.62e-03 GO:0030247 polysaccharide binding
4.95 7.89e-03 GO:0005539 glycosaminoglycan binding
4.25 1.16e-04 GO:0032403 protein complex binding
3.36 5.31e-03 GO:0030246 carbohydrate binding
1.33 1.17e-03 GO:0005515 protein binding