Motif ID: MZF1.p2

Z-value: 2.711


Transcription factors associated with MZF1.p2:

Gene SymbolEntrez IDGene Name
MZF1 7593 myeloid zinc finger 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
MZF1chr19_-_59084735,
chr19_-_59084630
0.165.5e-01Click!


Activity profile for motif MZF1.p2.

activity profile for motif MZF1.p2


Sorted Z-values histogram for motif MZF1.p2

Sorted Z-values for motif MZF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MZF1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_-_114538953 20.006 NM_001143945
GAS6
growth arrest-specific 6
chr5_+_17217781 12.832 BASP1
brain abundant, membrane attached signal protein 1
chr5_+_17217474 11.210 NM_006317
BASP1
brain abundant, membrane attached signal protein 1
chr10_-_126849010 9.627 CTBP2
C-terminal binding protein 2
chr10_-_126849066 9.139 NM_001329
CTBP2
C-terminal binding protein 2
chr2_-_161350304 8.433 NM_002897
NM_016836
RBMS1

RNA binding motif, single stranded interacting protein 1

chr2_-_161349874 7.786 RBMS1
RNA binding motif, single stranded interacting protein 1
chr2_-_56150862 6.834 EFEMP1
EGF containing fibulin-like extracellular matrix protein 1
chr10_-_126849556 6.536 NM_001083914
CTBP2
C-terminal binding protein 2
chr4_-_157892545 5.954 NM_016205
PDGFC
platelet derived growth factor C
chr7_-_150973819 5.920 NM_001003802
SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr5_+_82767492 4.781 NM_001126336
NM_001164097
NM_001164098
NM_004385
VCAN



versican



chr7_-_150974179 4.493 NM_003078
SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr2_-_216300770 4.349 NM_002026
NM_054034
NM_212474
NM_212476
NM_212478
NM_212482
FN1





fibronectin 1





chr2_-_56151273 4.230 NM_001039348
NM_001039349
EFEMP1

EGF containing fibulin-like extracellular matrix protein 1

chr19_+_41725098 4.213 NM_001699
NM_021913
AXL

AXL receptor tyrosine kinase

chrX_+_73641084 4.173 NM_006517
SLC16A2
solute carrier family 16, member 2 (monocarboxylic acid transporter 8)
chr12_+_53491417 4.014 NM_002178
IGFBP6
insulin-like growth factor binding protein 6
chr12_+_53491448 3.997 IGFBP6
insulin-like growth factor binding protein 6
chr16_-_65155881 3.968 NM_001797
CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 68 entries
Enrichment   P-value GO Accession GO Term
23.54 1.82e-02 GO:0034446 substrate adhesion-dependent cell spreading
11.03 1.61e-02 GO:0001843 neural tube closure
11.03 1.61e-02 GO:0060606 tube closure
10.70 1.94e-02 GO:0014020 primary neural tube formation
9.54 3.86e-02 GO:0001841 neural tube formation
7.36 4.85e-02 GO:0016331 morphogenesis of embryonic epithelium
7.14 1.71e-02 GO:0048706 embryonic skeletal system development
6.36 3.99e-02 GO:0002576 platelet degranulation
5.91 2.33e-09 GO:0048729 tissue morphogenesis
5.89 9.98e-04 GO:0060562 epithelial tube morphogenesis
5.50 2.82e-04 GO:0035239 tube morphogenesis
5.45 1.66e-02 GO:0048705 skeletal system morphogenesis
5.41 1.75e-05 GO:0002009 morphogenesis of an epithelium
5.30 2.12e-02 GO:0001763 morphogenesis of a branching structure
5.22 9.32e-03 GO:0001655 urogenital system development
5.00 9.09e-04 GO:0045664 regulation of neuron differentiation
4.70 4.55e-03 GO:0007517 muscle organ development
4.45 3.09e-04 GO:0035295 tube development
4.42 1.76e-03 GO:0050767 regulation of neurogenesis
4.34 1.75e-05 GO:0048598 embryonic morphogenesis

Gene overrepresentation in compartment category:

Showing 1 to 19 of 19 entries
Enrichment   P-value GO Accession GO Term
58.83 8.60e-04 GO:0005589 collagen type VI
26.15 1.69e-03 GO:0030934 anchoring collagen
25.22 2.86e-02 GO:0005606 laminin-1 complex
14.27 1.02e-05 GO:0005581 collagen
12.87 1.51e-04 GO:0042641 actomyosin
10.90 1.42e-02 GO:0001725 stress fiber
10.15 2.03e-02 GO:0032432 actin filament bundle
9.01 1.52e-08 GO:0044420 extracellular matrix part
7.51 2.36e-02 GO:0031093 platelet alpha granule lumen
7.36 7.39e-03 GO:0031091 platelet alpha granule
7.36 2.66e-02 GO:0034774 secretory granule lumen
7.06 3.35e-02 GO:0060205 cytoplasmic membrane-bounded vesicle lumen
6.79 4.17e-02 GO:0031983 vesicle lumen
5.53 4.25e-09 GO:0005578 proteinaceous extracellular matrix
4.58 1.88e-07 GO:0031012 extracellular matrix
3.18 2.34e-02 GO:0015629 actin cytoskeleton
2.61 1.03e-05 GO:0044421 extracellular region part
2.48 1.31e-03 GO:0005615 extracellular space
1.90 1.84e-03 GO:0005576 extracellular region

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
Enrichment   P-value GO Accession GO Term
7.79 4.40e-04 GO:0005201 extracellular matrix structural constituent
3.69 7.73e-04 GO:0003779 actin binding
2.79 4.39e-03 GO:0008092 cytoskeletal protein binding
2.18 1.20e-02 GO:0030528 transcription regulator activity
2.09 1.95e-02 GO:0005102 receptor binding
1.30 2.47e-03 GO:0005515 protein binding