Motif ID: NFE2.p2

Z-value: 1.299


Transcription factors associated with NFE2.p2:

Gene SymbolEntrez IDGene Name
NFE2 4778 nuclear factor (erythroid-derived 2), 45kDa

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NFE2chr12_-_54694717,
chr12_-_54689536,
chr12_-_54694647		0.165.6e-01Click!


Activity profile for motif NFE2.p2.

activity profile for motif NFE2.p2


Sorted Z-values histogram for motif NFE2.p2

Sorted Z-values for motif NFE2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFE2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_-_38721701 6.680 NM_001838
 CCR7
chemokine (C-C motif) receptor 7
chr22_+_23040394 5.202 IGL@
immunoglobulin lambda locus
chr22_+_23010757 5.033


chr22_+_22723972 3.709


chr22_+_23165273 3.351


chr12_-_15114495 3.313 NM_001175
 ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr13_-_99959649 3.237 NM_004951
 GPR183
G protein-coupled receptor 183
chr1_+_174844655 3.181 NM_001035230
 RABGAP1L
RAB GTPase activating protein 1-like
chr22_+_22569155 3.161


chr4_+_41258941 2.923 UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chrX_-_154563735 2.863 NM_001289
 CLIC2
chloride intracellular channel 2
chr5_+_150020201 2.786 NM_001109974
NM_007286
 SYNPO

synaptopodin

chrX_+_12993224 2.752 NM_021109
 TMSB4X
thymosin beta 4, X-linked
chr6_+_33043702 2.609 NM_002121
 HLA-DPB1
major histocompatibility complex, class II, DP beta 1
chr11_+_20385324 2.397 NM_001098522
 HTATIP2
HIV-1 Tat interactive protein 2, 30kDa
chr11_+_20385230 2.261 NM_006410
NM_001098521
 HTATIP2

HIV-1 Tat interactive protein 2, 30kDa

chr11_+_20385259 2.255 NM_001098520
 HTATIP2
HIV-1 Tat interactive protein 2, 30kDa
chr22_+_22758538 2.161


chr10_-_6019880 2.109 NM_001243539
 IL15RA
interleukin 15 receptor, alpha
chr9_-_123688352 2.100 TRAF1
TNF receptor-associated factor 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 16 of 16 entries
Enrichment   P-value GO Accession GO Term
147.95 3.12e-02 GO:0051772 regulation of nitric-oxide synthase 2 biosynthetic process
10.42 1.14e-02 GO:0050870 positive regulation of T cell activation
10.10 5.45e-04 GO:0019221 cytokine-mediated signaling pathway
9.26 4.85e-03 GO:0050867 positive regulation of cell activation
9.12 1.18e-03 GO:0071345 cellular response to cytokine stimulus
8.66 3.24e-02 GO:0051251 positive regulation of lymphocyte activation
8.50 3.60e-02 GO:0050863 regulation of T cell activation
8.09 4.74e-02 GO:0002696 positive regulation of leukocyte activation
7.05 2.84e-02 GO:0050865 regulation of cell activation
6.57 1.32e-02 GO:0034097 response to cytokine stimulus
5.23 2.37e-02 GO:0002684 positive regulation of immune system process
4.85 3.12e-04 GO:0006955 immune response
4.17 2.52e-02 GO:0002682 regulation of immune system process
4.08 2.72e-05 GO:0002376 immune system process
2.27 4.21e-02 GO:0048518 positive regulation of biological process
1.75 1.27e-02 GO:0050896 response to stimulus

Nothing significant found in compartment category.

Nothing significant found in function category.