Motif ID: NFE2L1.p2

Z-value: 1.700


Transcription factors associated with NFE2L1.p2:

Gene SymbolEntrez IDGene Name
NFE2L1 4779 nuclear factor (erythroid-derived 2)-like 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NFE2L1chr17_+_461256750.421.0e-01Click!


Activity profile for motif NFE2L1.p2.

activity profile for motif NFE2L1.p2


Sorted Z-values histogram for motif NFE2L1.p2

Sorted Z-values for motif NFE2L1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFE2L1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_-_10535476 3.658 NM_001193278
NM_001193279
NM_001193280
NM_001193281
 MID1



midline 1 (Opitz/BBB syndrome)



chr2_-_216259197 3.205 FN1
fibronectin 1
chr16_+_82660390 3.133 NM_001220488
NM_001220489
NM_001220490
NM_001220491
NM_001220492
NM_001257
 CDH13





cadherin 13, H-cadherin (heart)





chr3_+_158991035 3.111 NM_001197107
NM_001197108
NM_014575
 SCHIP1


schwannomin interacting protein 1


chr17_-_39780762 2.963 NM_000422
 KRT17
keratin 17
chr21_+_47545896 2.755 COL6A2
collagen, type VI, alpha 2
chr17_-_39743085 2.644 NM_000526
 KRT14
keratin 14
chr1_-_68697997 2.597 NM_001002292
NM_001193334
NM_024911
 WLS


wntless homolog (Drosophila)


chr12_+_13349720 2.524 EMP1
epithelial membrane protein 1
chr12_+_13349601 2.499 NM_001423
 EMP1
epithelial membrane protein 1
chr10_+_75673346 2.411 PLAU
plasminogen activator, urokinase
chr5_+_148206155 2.364 NM_000024
 ADRB2
adrenergic, beta-2-, receptor, surface
chr3_-_45267068 2.336 TMEM158
transmembrane protein 158 (gene/pseudogene)
chr12_-_52886971 2.289 NM_005554
 KRT6A
keratin 6A
chr16_+_82660573 2.237 CDH13
cadherin 13, H-cadherin (heart)
chr21_+_47545189 2.198 COL6A2
collagen, type VI, alpha 2
chr1_-_59042827 2.153 TACSTD2
tumor-associated calcium signal transducer 2
chr13_-_114566951 2.119 GAS6
growth arrest-specific 6
chr13_-_114567011 2.093 GAS6
growth arrest-specific 6
chr13_-_114567034 2.081 GAS6
growth arrest-specific 6

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 14 of 14 entries
Enrichment   P-value GO Accession GO Term
16.60 4.63e-02 GO:0042058 regulation of epidermal growth factor receptor signaling pathway
8.54 3.35e-02 GO:0001525 angiogenesis
7.17 6.78e-03 GO:0001568 blood vessel development
6.68 1.13e-02 GO:0001944 vasculature development
5.46 5.77e-03 GO:0051094 positive regulation of developmental process
4.91 1.45e-02 GO:0007596 blood coagulation
4.91 1.45e-02 GO:0050817 coagulation
4.87 1.54e-02 GO:0007599 hemostasis
4.55 1.11e-02 GO:0042060 wound healing
4.28 4.58e-02 GO:0050878 regulation of body fluid levels
3.85 4.92e-03 GO:0009611 response to wounding
3.21 9.83e-03 GO:0051239 regulation of multicellular organismal process
2.00 2.89e-02 GO:0032502 developmental process
1.92 3.21e-03 GO:0032501 multicellular organismal process

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
Enrichment   P-value GO Accession GO Term
19.95 5.39e-04 GO:0031983 vesicle lumen
17.66 8.45e-03 GO:0031093 platelet alpha granule lumen
17.30 9.18e-03 GO:0034774 secretory granule lumen
16.60 1.08e-02 GO:0060205 cytoplasmic membrane-bounded vesicle lumen
14.83 1.68e-02 GO:0031091 platelet alpha granule
7.87 4.79e-02 GO:0005912 adherens junction
2.49 3.04e-02 GO:0005576 extracellular region

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
Enrichment   P-value GO Accession GO Term
12.21 2.94e-02 GO:0005201 extracellular matrix structural constituent
11.86 3.28e-02 GO:0005200 structural constituent of cytoskeleton
4.52 2.25e-03 GO:0005198 structural molecule activity