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Motif ID: NFKB1_REL_RELA.p2

Z-value: 3.287

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr19_+_4229494	9.771	NM_005755	EBI3	Epstein-Barr virus induced 3
chr5_-_149792276	7.089		CD74	CD74 molecule, major histocompatibility complex, class II invariant chain
chr6_-_32551993	6.932		HLA-DRB1 HLA-DRB4 HLA-DRB5	major histocompatibility complex, class II, DR beta 1 major histocompatibility complex, class II, DR beta 4 major histocompatibility complex, class II, DR beta 5
chr22_+_22758538	6.696
chr11_+_102188180	6.532	NM_001165 NM_182962	BIRC3	baculoviral IAP repeat containing 3
chr19_-_6591012	6.249		CD70	CD70 molecule
chr5_-_149792370	5.950	NM_001025158 NM_001025159 NM_004355	CD74	CD74 molecule, major histocompatibility complex, class II invariant chain
chr6_+_32605182	5.718	NM_002122	HLA-DQA1	major histocompatibility complex, class II, DQ alpha 1
chr2_-_163174816	5.518	NM_022168	IFIH1	interferon induced with helicase C domain 1
chr6_-_31324975	5.470	NM_005514	HLA-B	major histocompatibility complex, class I, B
chr22_-_37545944	5.407	NM_000878	IL2RB	interleukin 2 receptor, beta
chr14_-_35873823	5.397	NM_020529	NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
chr12_+_7055736	5.072	NM_080548	PTPN6	protein tyrosine phosphatase, non-receptor type 6
chr22_+_23134980	5.050
chr6_+_14117486	5.006	NM_001251901	CD83	CD83 molecule
chr20_+_44746889	4.853	NM_001250 NM_152854	CD40	CD40 molecule, TNF receptor superfamily member 5
chr1_+_111770280	4.811	NM_001025197 NM_004000	CHI3L2	chitinase 3-like 2
chr7_+_69064316	4.808		AUTS2	autism susceptibility candidate 2
chr6_-_31324955	4.774		HLA-B	major histocompatibility complex, class I, B
chr16_+_85932766	4.663	NM_002163	IRF8	interferon regulatory factor 8
chr22_+_23213671	4.446		IGLV4-3	immunoglobulin lambda variable 4-3
chr6_+_116692098	4.430	NM_013352	DSE	dermatan sulfate epimerase
chr16_+_50776012	4.410	NM_001042412	CYLD	cylindromatosis (turban tumor syndrome)
chr14_+_103243832	4.345		TRAF3	TNF receptor-associated factor 3
chr12_+_7055753	4.295		PTPN6	protein tyrosine phosphatase, non-receptor type 6
chr19_+_42381189	4.204	NM_001783 NM_021601	CD79A	CD79a molecule, immunoglobulin-associated alpha
chr22_-_37640287	4.145	NM_002872	RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr11_+_121322848	4.073	NM_003105	SORL1	sortilin-related receptor, L(DLR class) A repeats containing
chr14_-_96180402	4.063	NM_001098725 NM_021966	TCL1A	T-cell leukemia/lymphoma 1A
chr19_-_6591082	4.054		CD70	CD70 molecule
chr16_+_50775960	4.042	NM_001042355 NM_015247	CYLD	cylindromatosis (turban tumor syndrome)
chr22_-_37640187	3.911		RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr10_+_12391708	3.903		CAMK1D	calcium/calmodulin-dependent protein kinase ID
chr17_+_65373574	3.895		PITPNC1	phosphatidylinositol transfer protein, cytoplasmic 1
chr6_-_31324898	3.772		HLA-B	major histocompatibility complex, class I, B
chr19_+_50922194	3.736	NM_001243998 NM_001243999 NM_001244000 NM_003121	SPIB	Spi-B transcription factor (Spi-1/PU.1 related)
chr14_+_75988765	3.696	NM_006399	BATF	basic leucine zipper transcription factor, ATF-like
chr14_+_75988838	3.685		BATF	basic leucine zipper transcription factor, ATF-like
chr6_+_14118002	3.667		CD83	CD83 molecule
chr6_+_29974352	3.613		HLA-J	major histocompatibility complex, class I, J (pseudogene)
chr19_-_7766978	3.585	NM_001220500 NM_002002	FCER2	Fc fragment of IgE, low affinity II, receptor for (CD23)
chr20_-_4795768	3.550	NM_170774	RASSF2	Ras association (RalGDS/AF-6) domain family member 2
chr10_+_30722856	3.517	NM_001244134 NM_005204	MAP3K8	mitogen-activated protein kinase kinase kinase 8
chr10_+_104155431	3.472	NM_002502	NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr13_-_46756326	3.430	NM_002298	LCP1	lymphocyte cytosolic protein 1 (L-plastin)
chr21_+_27011588	3.375	NM_021219	JAM2	junctional adhesion molecule 2
chr2_+_95691428	3.346	NM_002371 NM_022438 NM_022439 NM_022440	MAL	mal, T-cell differentiation protein
chr14_+_103243813	3.310	NM_001199427 NM_003300 NM_145725 NM_145726	TRAF3	TNF receptor-associated factor 3
chr6_+_29910246	3.271	NM_001242758 NM_002116	HLA-A	major histocompatibility complex, class I, A
chr19_-_11688441	3.228		ACP5	acid phosphatase 5, tartrate resistant
chr15_+_85923739	3.197	NM_006738 NM_007200	AKAP13	A kinase (PRKA) anchor protein 13
chr7_-_24797031	3.162		DFNA5	deafness, autosomal dominant 5
chr17_+_72462521	3.155	NM_007261	CD300A	CD300a molecule
chr22_+_23222897	3.029		CYAT1	immunoglobulin lambda light chain-like
chr5_-_150466696	2.980	NM_001252391 NM_001252392	TNIP1	TNFAIP3 interacting protein 1
chr22_+_22712091	2.978		IGLV1-44 IGL@	immunoglobulin lambda variable 1-44 immunoglobulin lambda locus
chr1_-_183560010	2.946	NM_001127651	NCF2	neutrophil cytosolic factor 2
chr6_-_29527701	2.937	NM_006398	UBD	ubiquitin D
chrX_+_12885190	2.934	NM_016562	TLR7	toll-like receptor 7
chr4_+_103422479	2.912	NM_001165412 NM_003998	NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr4_+_103422822	2.887		NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr4_+_103422730	2.882		NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr20_+_44746948	2.851		CD40	CD40 molecule, TNF receptor superfamily member 5
chr15_+_89182038	2.840	NM_002201	ISG20	interferon stimulated exonuclease gene 20kDa
chr11_-_57335756	2.836	NM_198183	UBE2L6	ubiquitin-conjugating enzyme E2L 6
chr19_+_2476122	2.829	NM_015675	GADD45B	growth arrest and DNA-damage-inducible, beta
chr6_-_29527477	2.742		UBD	ubiquitin D
chr1_-_183559669	2.618	NM_000433 NM_001190789 NM_001190794	NCF2	neutrophil cytosolic factor 2
chr6_+_138188352	2.618	NM_006290	TNFAIP3	tumor necrosis factor, alpha-induced protein 3
chr6_-_31324564	2.615		HLA-B HLA-C	major histocompatibility complex, class I, B major histocompatibility complex, class I, C
chr10_+_104154228	2.609	NM_001077493 NM_001077494	NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr19_-_6591136	2.590	NM_001252	CD70	CD70 molecule
chr6_+_31539875	2.574	NM_001159740	LTA	lymphotoxin alpha (TNF superfamily, member 1)
chrX_+_78200828	2.568	NM_014499 NM_198333	P2RY10	purinergic receptor P2Y, G-protein coupled, 10
chr2_+_208394692	2.560		CREB1	cAMP responsive element binding protein 1
chr19_+_3136026	2.559	NM_002068	GNA15	guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
chr1_-_27961623	2.551	NM_005248	FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr16_+_81812897	2.478	NM_002661	PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr19_-_44285407	2.469	NM_002250	KCNN4	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr6_-_32811773	2.461	NM_148919	PSMB8	proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)
chr8_-_70747200	2.455	NM_030958	SLCO5A1	solute carrier organic anion transporter family, member 5A1
chr8_-_22550708	2.435	NM_004430	EGR3	early growth response 3
chr21_+_27011766	2.429		JAM2	junctional adhesion molecule 2
chr16_+_50731049	2.418	NM_022162	NOD2	nucleotide-binding oligomerization domain containing 2
chr16_+_81812899	2.398		PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr1_+_203274646	2.382	NM_006763	BTG2	BTG family, member 2
chr19_-_44285012	2.342		KCNN4	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr13_-_46756295	2.333		LCP1	lymphocyte cytosolic protein 1 (L-plastin)
chr6_+_31540092	2.328	NM_000595	LTA	lymphotoxin alpha (TNF superfamily, member 1)
chr1_-_184943532	2.290		FAM129A	family with sequence similarity 129, member A
chr4_-_76944585	2.277	NM_001565	CXCL10	chemokine (C-X-C motif) ligand 10
chr3_+_121796695	2.272	NM_006889 NM_176892	CD86	CD86 molecule
chr5_-_150460599	2.252	NM_001252385 NM_001252386 NM_001252393 NM_006058	TNIP1	TNFAIP3 interacting protein 1
chr17_-_34207308	2.245	NM_002985	CCL5	chemokine (C-C motif) ligand 5
chr10_+_30723050	2.242		MAP3K8	mitogen-activated protein kinase kinase kinase 8
chr2_+_237478379	2.241	NM_020311	CXCR7	chemokine (C-X-C motif) receptor 7
chr5_-_150460550	2.231		TNIP1	TNFAIP3 interacting protein 1
chr1_-_25256767	2.228	NM_004350	RUNX3	runt-related transcription factor 3
chr5_-_142782754	2.225		NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr19_+_1067536	2.201		HMHA1	histocompatibility (minor) HA-1
chr3_-_58200397	2.168	NM_004944	DNASE1L3	deoxyribonuclease I-like 3
chr2_+_208394756	2.155		CREB1	cAMP responsive element binding protein 1
chr5_-_142783225	2.151	NM_000176 NM_001020825 NM_001024094 NM_001204258 NM_001204259 NM_001204260 NM_001204261 NM_001204262 NM_001204263 NM_001204264 NM_001204265	NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr2_+_208394823	2.122		CREB1	cAMP responsive element binding protein 1
chr1_-_182573393	2.112	NM_002928	RGS16	regulator of G-protein signaling 16
chr14_-_64970319	2.109	NM_006977	ZBTB25	zinc finger and BTB domain containing 25
chr7_+_114562140	2.108	NM_001166345 NM_001166346 NM_199072	MDFIC	MyoD family inhibitor domain containing
chr21_+_27012045	2.094		JAM2	junctional adhesion molecule 2
chr11_-_3862183	2.076	NM_001665	RHOG	ras homolog gene family, member G (rho G)
chr17_+_72462766	2.067		CD300A	CD300a molecule
chr8_+_38758752	2.057	NM_021623	PLEKHA2	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
chr19_+_45504686	2.053	NM_006509	RELB	v-rel reticuloendotheliosis viral oncogene homolog B
chr10_+_12391471	2.043	NM_020397 NM_153498	CAMK1D	calcium/calmodulin-dependent protein kinase ID
chr3_+_53195214	2.029	NM_006254 NM_212539	PRKCD	protein kinase C, delta
chr9_+_4490193	2.018	NM_004170	SLC1A1	solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
chr15_+_81589240	2.016	NM_004513	IL16	interleukin 16
chr2_+_61108702	2.011		REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)
chr11_-_3862137	1.990		RHOG	ras homolog gene family, member G (rho G)
chr2_+_61108775	1.980		REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)
chr2_-_197036262	1.971		STK17B	serine/threonine kinase 17b
chr6_+_29910308	1.947		HLA-A	major histocompatibility complex, class I, A
chr20_+_9495297	1.943		LAMP5	lysosomal-associated membrane protein family, member 5
chr2_+_61108724	1.940	NM_002908	REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)
chr6_+_29855506	1.935
chr1_-_93426998	1.931	NM_001006605 NM_001252269 NM_001252270 NM_001252273	FAM69A	family with sequence similarity 69, member A
chr5_-_171615239	1.918		STK10	serine/threonine kinase 10
chr21_+_27012067	1.899		JAM2	junctional adhesion molecule 2
chr4_+_103422553	1.891		NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr17_-_16875388	1.885	NM_012452	TNFRSF13B	tumor necrosis factor receptor superfamily, member 13B
chr5_-_171615320	1.874	NM_005990	STK10	serine/threonine kinase 10
chr5_-_142783200	1.867		NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr3_+_52232174	1.859		ALAS1	aminolevulinate, delta-, synthase 1
chr11_+_1889902	1.858	NM_001013253	LSP1	lymphocyte-specific protein 1
chr4_+_142557722	1.853	NM_000585 NM_172175	IL15	interleukin 15
chr5_-_150467220	1.836	NM_001252390	TNIP1	TNFAIP3 interacting protein 1
chrX_-_30595883	1.836	NM_025159	CXorf21	chromosome X open reading frame 21
chr5_-_142783059	1.817		NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr6_+_14117857	1.788	NM_001040280 NM_004233	CD83	CD83 molecule
chr3_+_52232076	1.787	NM_199166 NM_000688	ALAS1	aminolevulinate, delta-, synthase 1
chr1_-_209824641	1.768	NM_001017402	LAMB3	laminin, beta 3
chr6_-_32908583	1.755	NM_002118	HLA-DMB	major histocompatibility complex, class II, DM beta
chr5_-_171615095	1.726		STK10	serine/threonine kinase 10
chr22_+_22764094	1.695
chr7_+_7606549	1.693	NM_019005	MIOS	missing oocyte, meiosis regulator, homolog (Drosophila)
chr12_+_48499655	1.673	NM_001166686	PFKM	phosphofructokinase, muscle
chr6_+_29855349	1.635		HLA-H	major histocompatibility complex, class I, H (pseudogene)
chr11_-_77122877	1.635		PAK1	p21 protein (Cdc42/Rac)-activated kinase 1
chr6_-_132722564	1.633	NM_015529	MOXD1	monooxygenase, DBH-like 1
chr17_+_7461591	1.596	NM_001198622 NM_001198623 NM_001198624 NM_003808 NM_172087 NM_172088	TNFSF13	tumor necrosis factor (ligand) superfamily, member 13
chr6_+_292033	1.590	NM_020185	DUSP22	dual specificity phosphatase 22
chr17_-_7590731	1.576	NM_000546 NM_001126112 NM_001126113 NM_001126114	TP53	tumor protein p53
chr11_+_58910173	1.571	NM_001142519 NM_001142520 NM_001142521	FAM111A	family with sequence similarity 111, member A
chr2_+_233925035	1.563	NM_001017915 NM_005541	INPP5D	inositol polyphosphate-5-phosphatase, 145kDa
chr4_-_71532206	1.534		IGJ	immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr20_-_57582152	1.511		CTSZ	cathepsin Z
chr1_-_27952591	1.496	NM_001042747	FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr19_+_14142459	1.491		IL27RA	interleukin 27 receptor, alpha
chr14_+_65878579	1.484		FUT8	fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr1_-_183604885	1.483	NM_005717	ARPC5	actin related protein 2/3 complex, subunit 5, 16kDa
chr4_-_185395616	1.474	NM_002199	IRF2	interferon regulatory factor 2
chr15_-_66084544	1.458	NM_001144823 NM_005848	DENND4A	DENN/MADD domain containing 4A
chr6_+_135502445	1.458	NM_001130172 NM_001130173 NM_001161656 NM_001161657 NM_001161658 NM_001161659 NM_001161660 NM_005375	MYB	v-myb myeloblastosis viral oncogene homolog (avian)
chr19_+_14142611	1.458		IL27RA	interleukin 27 receptor, alpha
chr1_-_209825797	1.454	NM_000228	LAMB3	laminin, beta 3
chr7_+_7606634	1.450		MIOS	missing oocyte, meiosis regulator, homolog (Drosophila)
chr4_-_71532341	1.445	NM_144646	IGJ	immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr1_+_156123321	1.438	NM_001193300 NM_022367 NM_001193302	SEMA4A	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr2_+_208394615	1.423	NM_004379 NM_134442	CREB1	cAMP responsive element binding protein 1
chr14_+_64971226	1.420	NM_001123329 NM_014950	ZBTB1	zinc finger and BTB domain containing 1
chr1_-_212873306	1.415	NM_018664	BATF3	basic leucine zipper transcription factor, ATF-like 3
chr14_-_106691698	1.410
chr3_+_57261729	1.393	NM_012096	APPL1	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
chr17_+_72462780	1.391		CD300A	CD300a molecule
chr22_-_23922376	1.388	NM_020070 NM_152855	IGLL1	immunoglobulin lambda-like polypeptide 1
chr1_+_26856252	1.363		RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr10_+_90750384	1.354		FAS	Fas (TNF receptor superfamily, member 6)
chr3_+_57261778	1.344		APPL1	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
chr2_-_197036301	1.325	NM_004226	STK17B	serine/threonine kinase 17b
chr14_-_106692107	1.325		IGHV4-31 IGHA1 IGHD IGHG1 IGHG3	immunoglobulin heavy variable 4-31 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant delta immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 3 (G3m marker)
chr5_-_131826426	1.324	NM_002198	IRF1	interferon regulatory factor 1
chr14_-_24616429	1.322		PSME2	proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr1_-_183604793	1.312		ARPC5	actin related protein 2/3 complex, subunit 5, 16kDa
chrX_-_112084006	1.311	NM_133265	AMOT	angiomotin
chr6_+_29894105	1.294
chr1_-_202130677	1.291	NM_001199797 NM_002832	PTPN7	protein tyrosine phosphatase, non-receptor type 7
chr8_+_54793409	1.291	NM_003702	RGS20	regulator of G-protein signaling 20
chr1_+_183605207	1.287	NM_015149	RGL1	ral guanine nucleotide dissociation stimulator-like 1
chr1_+_207627614	1.269	NM_001006658 NM_001877	CR2	complement component (3d/Epstein Barr virus) receptor 2
chr12_-_54653317	1.247	NM_001127322	CBX5	chromobox homolog 5
chr16_-_21314371	1.244	NM_001014444 NM_001888	CRYM	crystallin, mu
chr11_-_64570621	1.228	NM_004579	MAP4K2	mitogen-activated protein kinase kinase kinase kinase 2
chr7_-_24797316	1.224		DFNA5	deafness, autosomal dominant 5
chr17_-_61819120	1.219		STRADA	STE20-related kinase adaptor alpha
chr19_+_16187315	1.206		TPM4	tropomyosin 4
chr5_+_96271345	1.205	NM_005575	LNPEP	leucyl/cystinyl aminopeptidase
chr12_-_54653369	1.203	NM_001127321	CBX5	chromobox homolog 5
chr22_-_24059436	1.186
chr6_+_106534210	1.176		PRDM1	PR domain containing 1, with ZNF domain
chr7_-_129592794	1.168	NM_003344 NM_182697	UBE2H	ubiquitin-conjugating enzyme E2H
chr3_+_52232179	1.152		ALAS1	aminolevulinate, delta-, synthase 1

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
6.75	4.46e-25	GO:0006955	immune response
5.03	1.83e-24	GO:0002376	immune system process
6.70	2.34e-13	GO:0002684	positive regulation of immune system process
6.16	2.32e-11	GO:0050776	regulation of immune response
8.11	2.84e-11	GO:0001817	regulation of cytokine production
4.56	4.53e-11	GO:0006952	defense response
4.67	4.03e-10	GO:0002682	regulation of immune system process
8.71	5.17e-10	GO:0051249	regulation of lymphocyte activation
7.21	1.19e-09	GO:0050778	positive regulation of immune response
2.45	2.16e-09	GO:0048518	positive regulation of biological process
7.93	2.80e-09	GO:0002694	regulation of leukocyte activation
9.01	5.48e-09	GO:0002764	immune response-regulating signaling pathway
7.61	5.87e-09	GO:0050865	regulation of cell activation
9.20	1.75e-08	GO:0051251	positive regulation of lymphocyte activation
1.76	2.43e-08	GO:0050896	response to stimulus
8.64	4.58e-08	GO:0002757	immune response-activating signal transduction
8.58	5.03e-08	GO:0002696	positive regulation of leukocyte activation
5.88	5.70e-08	GO:0045087	innate immune response
8.43	6.61e-08	GO:0050867	positive regulation of cell activation
6.94	1.20e-06	GO:0002253	activation of immune response
3.73	1.23e-06	GO:0048584	positive regulation of response to stimulus
7.55	1.29e-06	GO:0019221	cytokine-mediated signaling pathway
2.05	1.69e-06	GO:0007165	signal transduction
8.99	2.01e-06	GO:0050870	positive regulation of T cell activation
2.30	2.45e-06	GO:0006950	response to stress
2.57	2.66e-06	GO:0048583	regulation of response to stimulus
3.23	4.69e-06	GO:0043067	regulation of programmed cell death
1.95	5.03e-06	GO:0023052	signaling
6.81	5.32e-06	GO:0071345	cellular response to cytokine stimulus
3.18	6.53e-06	GO:0010941	regulation of cell death
5.56	1.06e-05	GO:0034097	response to cytokine stimulus
4.41	1.08e-05	GO:0001775	cell activation
6.29	1.55e-05	GO:0045321	leukocyte activation
3.14	1.58e-05	GO:0042981	regulation of apoptosis
9.64	1.77e-05	GO:0002768	immune response-regulating cell surface receptor signaling pathway
1.52	1.90e-05	GO:0050789	regulation of biological process
1.55	2.35e-05	GO:0050794	regulation of cellular process
7.33	2.44e-05	GO:0050863	regulation of T cell activation
2.23	4.01e-05	GO:0048519	negative regulation of biological process
3.26	4.34e-05	GO:0051704	multi-organism process
1.81	4.82e-05	GO:0051716	cellular response to stimulus
2.18	5.10e-05	GO:0048522	positive regulation of cellular process
2.44	5.11e-05	GO:0007166	cell surface receptor linked signaling pathway
1.47	6.70e-05	GO:0065007	biological regulation
11.38	8.62e-05	GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
11.06	1.11e-04	GO:0002250	adaptive immune response
7.92	1.39e-04	GO:0001819	positive regulation of cytokine production
9.03	1.52e-04	GO:0002429	immune response-activating cell surface receptor signaling pathway
23.08	1.64e-04	GO:0002712	regulation of B cell mediated immunity
23.08	1.64e-04	GO:0002889	regulation of immunoglobulin mediated immune response
12.87	1.73e-04	GO:0050864	regulation of B cell activation
10.35	2.00e-04	GO:0034341	response to interferon-gamma
6.68	2.40e-04	GO:0070201	regulation of establishment of protein localization
21.23	2.83e-04	GO:0032655	regulation of interleukin-12 production
11.61	3.96e-04	GO:0060333	interferon-gamma-mediated signaling pathway
6.29	4.65e-04	GO:0046649	lymphocyte activation
2.75	5.15e-04	GO:0010604	positive regulation of macromolecule metabolic process
6.96	5.20e-04	GO:0002697	regulation of immune effector process
14.08	5.59e-04	GO:0032649	regulation of interferon-gamma production
4.42	6.88e-04	GO:0051707	response to other organism
27.65	6.90e-04	GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
3.44	7.23e-04	GO:0071310	cellular response to organic substance
8.85	7.73e-04	GO:0050851	antigen receptor-mediated signaling pathway
7.57	8.04e-04	GO:0002521	leukocyte differentiation
10.57	8.27e-04	GO:0071346	cellular response to interferon-gamma
5.87	9.69e-04	GO:0032880	regulation of protein localization
4.92	9.94e-04	GO:0002520	immune system development
6.37	1.26e-03	GO:0031349	positive regulation of defense response
9.70	1.61e-03	GO:0050852	T cell receptor signaling pathway
11.91	1.81e-03	GO:0019882	antigen processing and presentation
6.86	1.98e-03	GO:0002252	immune effector process
3.85	2.00e-03	GO:0009607	response to biotic stimulus
5.45	2.13e-03	GO:0009617	response to bacterium
2.50	2.28e-03	GO:0010033	response to organic substance
4.92	2.47e-03	GO:0048534	hemopoietic or lymphoid organ development
11.26	2.67e-03	GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
2.52	3.01e-03	GO:0009893	positive regulation of metabolic process
11.06	3.02e-03	GO:0002819	regulation of adaptive immune response
8.74	3.57e-03	GO:0002224	toll-like receptor signaling pathway
2.08	3.75e-03	GO:0048523	negative regulation of cellular process
8.64	3.92e-03	GO:0001818	negative regulation of cytokine production
10.50	4.32e-03	GO:0031294	lymphocyte costimulation
10.50	4.32e-03	GO:0031295	T cell costimulation
4.34	4.41e-03	GO:0031347	regulation of defense response
8.33	5.14e-03	GO:0002221	pattern recognition receptor signaling pathway
6.93	6.06e-03	GO:0045089	positive regulation of innate immune response
8.05	6.68e-03	GO:0002758	innate immune response-activating signal transduction
7.96	7.27e-03	GO:0002218	activation of innate immune response
7.96	7.27e-03	GO:0030098	lymphocyte differentiation
2.71	7.49e-03	GO:0070887	cellular response to chemical stimulus
3.28	9.27e-03	GO:0050878	regulation of body fluid levels
12.07	9.45e-03	GO:0032479	regulation of type I interferon production
17.02	9.49e-03	GO:0032088	negative regulation of NF-kappaB transcription factor activity
6.48	1.05e-02	GO:0032496	response to lipopolysaccharide
3.39	1.12e-02	GO:0080134	regulation of response to stress
16.39	1.15e-02	GO:0032480	negative regulation of type I interferon production
16.39	1.15e-02	GO:0050830	defense response to Gram-positive bacterium
7.38	1.28e-02	GO:0070663	regulation of leukocyte proliferation
5.50	1.43e-02	GO:0045088	regulation of innate immune response
1.94	1.54e-02	GO:0042221	response to chemical stimulus
8.61	1.65e-02	GO:0042035	regulation of cytokine biosynthetic process
8.49	1.81e-02	GO:0002699	positive regulation of immune effector process
1.76	1.81e-02	GO:0060255	regulation of macromolecule metabolic process
3.82	1.88e-02	GO:0044419	interspecies interaction between organisms
8.37	1.98e-02	GO:0043900	regulation of multi-organism process
10.62	2.01e-02	GO:0042108	positive regulation of cytokine biosynthetic process
5.90	2.23e-02	GO:0002237	response to molecule of bacterial origin
3.34	2.41e-02	GO:0007596	blood coagulation
3.34	2.41e-02	GO:0050817	coagulation
10.21	2.53e-02	GO:0016064	immunoglobulin mediated immune response
3.32	2.62e-02	GO:0007599	hemostasis
4.64	2.63e-02	GO:0030097	hemopoiesis
2.57	2.71e-02	GO:0042127	regulation of cell proliferation
7.94	2.80e-02	GO:0042742	defense response to bacterium
44.23	2.80e-02	GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin
10.02	2.83e-02	GO:0019724	B cell mediated immunity
2.31	3.44e-02	GO:0051239	regulation of multicellular organismal process
5.57	3.52e-02	GO:0051223	regulation of protein transport
9.48	3.89e-02	GO:0002706	regulation of lymphocyte mediated immunity
19.66	4.30e-02	GO:0046631	alpha-beta T cell activation
3.51	4.68e-02	GO:0060341	regulation of cellular localization
37.91	4.85e-02	GO:0002923	regulation of humoral immune response mediated by circulating immunoglobulin

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
70.77	1.02e-05	GO:0033256	I-kappaB/NF-kappaB complex
31.60	4.17e-05	GO:0042613	MHC class II protein complex
17.70	1.17e-04	GO:0042611	MHC protein complex
1.76	2.38e-04	GO:0071944	cell periphery
1.72	7.78e-04	GO:0005886	plasma membrane
5.53	1.32e-02	GO:0009897	external side of plasma membrane
88.45	1.67e-02	GO:0033257	Bcl3/NF-kappaB2 complex
7.08	2.62e-02	GO:0009898	internal side of plasma membrane

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
5.30	3.12e-03	GO:0005125	cytokine activity
11.06	1.32e-02	GO:0003823	antigen binding
1.34	1.69e-02	GO:0005515	protein binding