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Motif ID: NHLH1,2.p2

Z-value: 2.361

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr10_+_17271277	4.935		VIM	vimentin
chr10_+_17271341	4.897		VIM	vimentin
chr10_+_17271302	4.850		VIM	vimentin
chr10_+_17271276	4.771		VIM	vimentin
chr13_-_114566951	4.623		GAS6	growth arrest-specific 6
chr4_-_57976550	4.324	NM_001253835 NM_001553	IGFBP7	insulin-like growth factor binding protein 7
chr14_-_52535737	4.223		NID2	nidogen 2 (osteonidogen)
chr11_-_6341708	4.156	NM_145040	PRKCDBP	protein kinase C, delta binding protein
chr14_-_52535711	3.870		NID2	nidogen 2 (osteonidogen)
chr13_-_114567011	3.840		GAS6	growth arrest-specific 6
chr9_-_35689799	3.757		TPM2	tropomyosin 2 (beta)
chr14_-_52535765	3.735		NID2	nidogen 2 (osteonidogen)
chr4_-_57976516	3.697		IGFBP7	insulin-like growth factor binding protein 7
chr2_-_230135954	3.609	NM_001100818 NM_017933	PID1	phosphotyrosine interaction domain containing 1
chr3_-_149688886	3.562		PFN2	profilin 2
chr10_+_124220990	3.522	NM_002775	HTRA1	HtrA serine peptidase 1
chr9_-_35689902	3.513	NM_003289 NM_213674	TPM2	tropomyosin 2 (beta)
chr13_-_114567034	3.350		GAS6	growth arrest-specific 6
chr11_-_35547144	3.138	NM_001001991 NM_015430	PAMR1	peptidase domain containing associated with muscle regeneration 1
chr4_-_80994183	3.065
chr2_-_1748240	3.025		PXDN	peroxidasin homolog (Drosophila)
chr7_+_130131921	3.009	NM_002402	MEST	mesoderm specific transcript homolog (mouse)
chr7_+_102553343	2.882	NM_001031692 NM_005824	LRRC17	leucine rich repeat containing 17
chr12_-_21810733	2.818		LDHB	lactate dehydrogenase B
chrX_+_135229536	2.807	NM_001159702 NM_001159703 NM_001449	FHL1	four and a half LIM domains 1
chr12_-_21810769	2.762		LDHB	lactate dehydrogenase B
chr13_-_114567040	2.725	NM_000820	GAS6	growth arrest-specific 6
chr14_+_90863365	2.652		CALM1	calmodulin 1 (phosphorylase kinase, delta)
chr4_+_174089889	2.566	NM_017423	GALNT7	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
chr7_-_131241321	2.562	NM_001018111 NM_005397	PODXL	podocalyxin-like
chr15_+_74218962	2.545		LOXL1	lysyl oxidase-like 1
chr4_-_41216455	2.525	NM_001166050 NM_004307 NM_173075	APBB2	amyloid beta (A4) precursor protein-binding, family B, member 2
chr12_-_54813002	2.422		ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr3_-_73673978	2.375	NM_015009	PDZRN3	PDZ domain containing ring finger 3
chr8_+_31497267	2.300	NM_013962	NRG1	neuregulin 1
chr21_+_42540092	2.277		BACE2	beta-site APP-cleaving enzyme 2
chr19_+_16187047	2.265	NM_003290	TPM4	tropomyosin 4
chr9_-_117880411	2.211	NM_002160	TNC	tenascin C
chr20_-_57582303	2.163	NM_001336	CTSZ	cathepsin Z
chr12_-_54813010	2.150	NM_002205	ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr4_-_99579540	2.147	NM_005723	TSPAN5	tetraspanin 5
chr3_-_149688638	2.131	NM_002628 NM_053024	PFN2	profilin 2
chr15_-_48937795	2.067	NM_000138	FBN1	fibrillin 1
chr1_+_77747727	1.999		AK5	adenylate kinase 5
chr1_+_28919006	1.991	NM_001193532	RAB42	RAB42, member RAS oncogene family
chr14_-_52535945	1.985	NM_007361	NID2	nidogen 2 (osteonidogen)
chr12_-_21810754	1.981		LDHB	lactate dehydrogenase B
chr17_-_15165860	1.942		PMP22	peripheral myelin protein 22
chr14_+_90863302	1.923	NM_006888	CALM1	calmodulin 1 (phosphorylase kinase, delta)
chr11_-_66084501	1.875	NM_020404	CD248	CD248 molecule, endosialin
chrX_-_13956530	1.866		GPM6B	glycoprotein M6B
chr1_-_85930610	1.861		DDAH1	dimethylarginine dimethylaminohydrolase 1
chr12_+_6309475	1.837	NM_001769	CD9	CD9 molecule
chr2_+_5832778	1.816	NM_003108	SOX11	SRY (sex determining region Y)-box 11
chr1_+_86046434	1.810	NM_001554	CYR61	cysteine-rich, angiogenic inducer, 61
chr9_-_139940595	1.798	NM_015392	NPDC1	neural proliferation, differentiation and control, 1
chr21_+_46494433	1.757	NM_001112 NM_001160230 NM_015833 NM_015834	ADARB1	adenosine deaminase, RNA-specific, B1
chr10_-_126849010	1.751		CTBP2	C-terminal binding protein 2
chr5_-_136834887	1.750	NM_004598	SPOCK1	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr6_-_167040700	1.749	NM_021135	RPS6KA2	ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr3_-_87040246	1.739	NM_016206	VGLL3	vestigial like 3 (Drosophila)
chr9_-_139940556	1.731		NPDC1	neural proliferation, differentiation and control, 1
chr12_-_47473424	1.719	NM_001143668 NM_181847	AMIGO2	adhesion molecule with Ig-like domain 2
chr1_-_85930733	1.712	NM_012137	DDAH1	dimethylarginine dimethylaminohydrolase 1
chr1_-_95392501	1.696	NM_001839	CNN3	calponin 3, acidic
chr1_+_99127146	1.694	NM_015976 NM_152238	SNX7	sorting nexin 7
chr9_-_139940464	1.675		NPDC1	neural proliferation, differentiation and control, 1
chr2_-_37899227	1.660	NM_006449	CDC42EP3	CDC42 effector protein (Rho GTPase binding) 3
chr7_+_17338182	1.644	NM_001621	AHR	aryl hydrocarbon receptor
chr11_+_86511490	1.630	NM_007173	PRSS23	protease, serine, 23
chr8_-_98290072	1.623		TSPYL5	TSPY-like 5
chr3_-_45267068	1.623		TMEM158	transmembrane protein 158 (gene/pseudogene)
chr7_+_98246595	1.620	NM_002523	NPTX2	neuronal pentraxin II
chr14_-_61747956	1.615		TMEM30B	transmembrane protein 30B
chr19_-_58609606	1.612	NM_001145543 NM_001145544 NM_023926	ZSCAN18	zinc finger and SCAN domain containing 18
chr5_+_102201713	1.610		PAM	peptidylglycine alpha-amidating monooxygenase
chr3_+_8543508	1.604	NM_014583	LMCD1	LIM and cysteine-rich domains 1
chr19_+_16187266	1.593		TPM4	tropomyosin 4
chr12_-_69326946	1.587	NM_001005502 NM_198320	CPM	carboxypeptidase M
chr12_-_76424474	1.584		PHLDA1	pleckstrin homology-like domain, family A, member 1
chr11_+_44587140	1.583	NM_001024844 NM_002231	CD82	CD82 molecule
chrX_-_38079980	1.581	NM_001170750 NM_001170751 NM_001170752 NM_006307	SRPX	sushi-repeat containing protein, X-linked
chr19_+_16187306	1.576		TPM4	tropomyosin 4
chr19_+_38755422	1.561		SPINT2	serine peptidase inhibitor, Kunitz type, 2
chrX_-_140271275	1.537		LDOC1	leucine zipper, down-regulated in cancer 1
chr12_-_54812936	1.535		ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr21_+_27011588	1.521	NM_021219	JAM2	junctional adhesion molecule 2
chr20_+_19870209	1.519	NM_018993	RIN2	Ras and Rab interactor 2
chr12_+_53491417	1.503	NM_002178	IGFBP6	insulin-like growth factor binding protein 6
chr1_-_193155723	1.475	NM_003783	B3GALT2	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr12_-_110318178	1.450	NM_016433	GLTP	glycolipid transfer protein
chr8_-_98290171	1.450	NM_033512	TSPYL5	TSPY-like 5
chr2_-_1748317	1.448		PXDN	peroxidasin homolog (Drosophila)
chr9_+_124030455	1.447		GSN	gelsolin
chr19_+_16187315	1.440		TPM4	tropomyosin 4
chr6_-_109776946	1.429		MICAL1	microtubule associated monoxygenase, calponin and LIM domain containing 1
chr1_-_201346783	1.427		TNNT2	troponin T type 2 (cardiac)
chr3_+_49059046	1.424	NM_199069 NM_199070	NDUFAF3	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3
chr2_-_227663454	1.419	NM_005544	IRS1	insulin receptor substrate 1
chr1_-_94703252	1.415	NM_004815	ARHGAP29	Rho GTPase activating protein 29
chr5_-_175843531	1.413	NM_001834 NM_007097	CLTB	clathrin, light chain B
chrX_+_80457597	1.401		SH3BGRL	SH3 domain binding glutamic acid-rich protein like
chr12_+_4430346	1.388	NM_020375	C12orf5	chromosome 12 open reading frame 5
chr1_-_59248287	1.376		JUN	jun proto-oncogene
chrX_+_153046422	1.365	NM_001170760 NM_001170761 NM_014370	SRPK3	SRSF protein kinase 3
chr2_-_1748285	1.357	NM_012293	PXDN	peroxidasin homolog (Drosophila)
chr6_+_129204285	1.355	NM_000426 NM_001079823	LAMA2	laminin, alpha 2
chr1_+_165600433	1.346		MGST3	microsomal glutathione S-transferase 3
chr11_+_44587212	1.318		CD82	CD82 molecule
chrX_-_13956644	1.307	NM_001001994	GPM6B	glycoprotein M6B
chr3_+_49059490	1.293		NDUFAF3	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3
chr5_-_16936371	1.280	NM_012334	MYO10	myosin X
chr1_-_201465700	1.273	NM_001193572	CSRP1	cysteine and glycine-rich protein 1
chr2_+_36583369	1.248	NM_016441	CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr12_+_79258588	1.242		SYT1	synaptotagmin I
chr11_+_832965	1.234		CD151	CD151 molecule (Raph blood group)
chrX_-_154688260	1.229	NM_001007523 NM_001007524 NM_012151	F8A2 F8A3 F8A1	coagulation factor VIII-associated 2 coagulation factor VIII-associated 3 coagulation factor VIII-associated 1
chr18_+_33877630	1.214	NM_025135	FHOD3	formin homology 2 domain containing 3
chr3_-_133969563	1.208	NM_001005861 NM_002958	RYK	RYK receptor-like tyrosine kinase
chr9_+_114393543	1.201	NM_001015882 NM_004125	DNAJC25 DNAJC25-GNG10	DnaJ (Hsp40) homolog, subfamily C , member 25 DNAJC25-GNG10 readthrough
chrX_-_107018889	1.193		TSC22D3	TSC22 domain family, member 3
chr20_-_57582152	1.193		CTSZ	cathepsin Z
chr1_+_51701943	1.190	NM_014372	RNF11	ring finger protein 11
chr5_-_175843360	1.188		CLTB	clathrin, light chain B
chr11_+_833007	1.184		CD151	CD151 molecule (Raph blood group)
chr1_-_201346804	1.179	NM_000364 NM_001001430 NM_001001431 NM_001001432	TNNT2	troponin T type 2 (cardiac)
chr11_-_125366048	1.178	NM_005103 NM_022549	FEZ1	fasciculation and elongation protein zeta 1 (zygin I)
chr6_-_46459010	1.176	NM_001251974	RCAN2	regulator of calcineurin 2
chr6_-_109776832	1.170		MICAL1	microtubule associated monoxygenase, calponin and LIM domain containing 1
chr11_+_832909	1.156	NM_001039490 NM_004357 NM_139029 NM_139030	CD151	CD151 molecule (Raph blood group)
chr13_+_50070096	1.155		PHF11	PHD finger protein 11
chr2_-_235405692	1.151	NM_005737	ARL4C	ADP-ribosylation factor-like 4C
chr6_-_139695739	1.138		CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr1_+_51701995	1.138		RNF11	ring finger protein 11
chr4_+_78079302	1.136		CCNG2	cyclin G2
chrX_+_73641084	1.133	NM_006517	SLC16A2	solute carrier family 16, member 2 (monocarboxylic acid transporter 8)
chr2_-_55277698	1.131	NM_020532 NM_153828 NM_207520	RTN4	reticulon 4
chr10_+_11059854	1.126	NM_006561	CELF2	CUGBP, Elav-like family member 2
chr19_+_38755238	1.122		SPINT2	serine peptidase inhibitor, Kunitz type, 2
chr3_-_45187861	1.116		CDCP1	CUB domain containing protein 1
chr12_+_79258517	1.115		SYT1	synaptotagmin I
chr1_-_156647088	1.115	NM_006617	NES	nestin
chr1_+_77747602	1.113	NM_174858	AK5	adenylate kinase 5
chr12_-_77272767	1.112	NM_001321	CSRP2	cysteine and glycine-rich protein 2
chr6_+_139456240	1.108	NM_016217	HECA	headcase homolog (Drosophila)
chr3_-_124606129	1.100	NM_002213	ITGB5	integrin, beta 5
chr14_-_75078669	1.097	NM_000428	LTBP2	latent transforming growth factor beta binding protein 2
chr6_-_109776942	1.094		MICAL1	microtubule associated monoxygenase, calponin and LIM domain containing 1
chr2_+_233498206	1.094	NM_025202	EFHD1	EF-hand domain family, member D1
chr2_+_202899309	1.087	NM_003507	FZD7	frizzled family receptor 7
chr3_-_145878775	1.087		PLOD2	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr13_-_110959441	1.083	NM_001845	COL4A1	collagen, type IV, alpha 1
chr11_-_102668822	1.083		MMP1	matrix metallopeptidase 1 (interstitial collagenase)
chr12_-_56101667	1.073	NM_001144996 NM_002206	ITGA7	integrin, alpha 7
chr1_+_165600109	1.072	NM_004528	MGST3	microsomal glutathione S-transferase 3
chr13_-_45150391	1.072		TSC22D1	TSC22 domain family, member 1
chr17_-_15554809	1.060		TRIM16	tripartite motif containing 16
chr1_+_25071759	1.059	NM_013943	CLIC4	chloride intracellular channel 4
chr18_+_3247774	1.059		MYL12A	myosin, light chain 12A, regulatory, non-sarcomeric
chr2_+_191745791	1.056		GLS	glutaminase
chr2_-_55277459	1.054		RTN4	reticulon 4
chr5_-_176899870	1.053	NM_080881	DBN1	drebrin 1
chr2_+_238395863	1.052	NM_001042467 NM_024101	MLPH	melanophilin
chr15_+_63340314	1.040	NM_001018008	TPM1	tropomyosin 1 (alpha)
chr9_+_90340973	1.029	NM_001912 NM_145918	CTSL1	cathepsin L1
chr3_+_158787040	1.028	NM_001197113 NM_001197114 NM_001042705 NM_001042706 NM_001197100	IQCJ-SCHIP1 IQCJ	IQCJ-SCHIP1 readthrough IQ motif containing J
chr7_+_69063768	1.026	NM_001127231 NM_001127232 NM_015570	AUTS2	autism susceptibility candidate 2
chr13_+_50069745	1.022	NM_001040443	PHF11	PHD finger protein 11
chr9_+_124030413	1.021		GSN	gelsolin
chr7_+_44788453	1.019	NM_031449	ZMIZ2	zinc finger, MIZ-type containing 2
chr3_-_45187843	1.016		CDCP1	CUB domain containing protein 1
chr22_+_31489343	1.008		SMTN	smoothelin
chr19_+_3094528	0.996		GNA11	guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
chr19_+_38755097	0.995	NM_001166103 NM_021102	SPINT2	serine peptidase inhibitor, Kunitz type, 2
chr17_-_15165873	0.987	NM_153321	PMP22	peripheral myelin protein 22
chr4_-_122618129	0.982		ANXA5	annexin A5
chr3_-_45187897	0.981	NM_022842 NM_178181	CDCP1	CUB domain containing protein 1
chr1_-_203154304	0.978		CHI3L1	chitinase 3-like 1 (cartilage glycoprotein-39)
chr4_-_57976355	0.975		IGFBP7	insulin-like growth factor binding protein 7
chr1_+_25071967	0.974		CLIC4	chloride intracellular channel 4
chr15_-_78369825	0.974	NM_015079 NM_144572	TBC1D2B	TBC1 domain family, member 2B
chr7_-_2883649	0.970	NM_007353	GNA12	guanine nucleotide binding protein (G protein) alpha 12
chr12_-_56122800	0.964		CD63	CD63 molecule
chr18_+_9334820	0.963		TWSG1	twisted gastrulation homolog 1 (Drosophila)
chr1_-_47184730	0.963	NM_014774	KIAA0494	KIAA0494
chr22_-_51021200	0.960		CHKB	choline kinase beta
chr4_-_122618140	0.959	NM_001154	ANXA5	annexin A5
chr3_-_55515361	0.954		WNT5A	wingless-type MMTV integration site family, member 5A
chr3_+_57261778	0.951		APPL1	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
chr1_-_57045129	0.950		PPAP2B	phosphatidic acid phosphatase type 2B
chr6_-_139695784	0.948	NM_006079	CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr11_-_66335958	0.943	NM_003793	CTSF	cathepsin F
chr10_+_123923104	0.939	NM_006997 NM_206860	TACC2	transforming, acidic coiled-coil containing protein 2
chr11_-_10830034	0.939		EIF4G2	eukaryotic translation initiation factor 4 gamma, 2
chr4_-_122618098	0.938		ANXA5	annexin A5
chr1_+_218519576	0.937		TGFB2	transforming growth factor, beta 2
chr6_+_86159738	0.935		NT5E	5'-nucleotidase, ecto (CD73)
chr7_+_94023872	0.934	NM_000089	COL1A2	collagen, type I, alpha 2
chr5_+_102201526	0.933	NM_000919 NM_001177306 NM_138766 NM_138821 NM_138822	PAM	peptidylglycine alpha-amidating monooxygenase
chrX_+_154114609	0.932	NM_001007523 NM_001007524 NM_012151	F8A2 F8A3 F8A1	coagulation factor VIII-associated 2 coagulation factor VIII-associated 3 coagulation factor VIII-associated 1

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
4.87	8.59e-03	GO:0061061	muscle structure development
5.97	1.08e-02	GO:0006936	muscle contraction
13.79	1.61e-02	GO:0030049	muscle filament sliding
13.79	1.61e-02	GO:0033275	actin-myosin filament sliding
5.64	1.69e-02	GO:0007517	muscle organ development
13.43	1.83e-02	GO:0070252	actin-mediated cell contraction
5.47	2.15e-02	GO:0003012	muscle system process

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
5.52	2.59e-05	GO:0015629	actin cytoskeleton
4.83	1.31e-04	GO:0031012	extracellular matrix
76.51	4.76e-04	GO:0005862	muscle thin filament tropomyosin
31.39	7.53e-04	GO:0005865	striated muscle thin filament
2.08	9.18e-03	GO:0005576	extracellular region
4.17	1.74e-02	GO:0005578	proteinaceous extracellular matrix
8.80	3.20e-02	GO:0005604	basement membrane

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
25.51	1.50e-04	GO:0005520	insulin-like growth factor binding
8.09	8.03e-04	GO:0019838	growth factor binding
4.15	8.62e-03	GO:0003779	actin binding
3.23	1.29e-02	GO:0008092	cytoskeletal protein binding