Motif ID: NHLH1,2.p2

Z-value: 2.361


Transcription factors associated with NHLH1,2.p2:

Gene SymbolEntrez IDGene Name
NHLH1 4807 nescient helix loop helix 1
NHLH2 4808 nescient helix loop helix 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NHLH2chr1_-_1163833230.476.7e-02Click!
NHLH1chr1_+_160336856-0.136.4e-01Click!


Activity profile for motif NHLH1,2.p2.

activity profile for motif NHLH1,2.p2


Sorted Z-values histogram for motif NHLH1,2.p2

Sorted Z-values for motif NHLH1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NHLH1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_+_17271277 4.935 VIM
vimentin
chr10_+_17271341 4.897 VIM
vimentin
chr10_+_17271302 4.850 VIM
vimentin
chr10_+_17271276 4.771 VIM
vimentin
chr13_-_114566951 4.623 GAS6
growth arrest-specific 6
chr4_-_57976550 4.324 NM_001253835
NM_001553
 IGFBP7

insulin-like growth factor binding protein 7

chr14_-_52535737 4.223 NID2
nidogen 2 (osteonidogen)
chr11_-_6341708 4.156 NM_145040
 PRKCDBP
protein kinase C, delta binding protein
chr14_-_52535711 3.870 NID2
nidogen 2 (osteonidogen)
chr13_-_114567011 3.840 GAS6
growth arrest-specific 6
chr9_-_35689799 3.757 TPM2
tropomyosin 2 (beta)
chr14_-_52535765 3.735 NID2
nidogen 2 (osteonidogen)
chr4_-_57976516 3.697 IGFBP7
insulin-like growth factor binding protein 7
chr2_-_230135954 3.609 NM_001100818
NM_017933
 PID1

phosphotyrosine interaction domain containing 1

chr3_-_149688886 3.562 PFN2
profilin 2
chr10_+_124220990 3.522 NM_002775
 HTRA1
HtrA serine peptidase 1
chr9_-_35689902 3.513 NM_003289
NM_213674
 TPM2

tropomyosin 2 (beta)

chr13_-_114567034 3.350 GAS6
growth arrest-specific 6
chr11_-_35547144 3.138 NM_001001991
NM_015430
 PAMR1

peptidase domain containing associated with muscle regeneration 1

chr4_-_80994183 3.065



Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 7 of 7 entries
Enrichment   P-value GO Accession GO Term
13.79 1.61e-02 GO:0030049 muscle filament sliding
13.79 1.61e-02 GO:0033275 actin-myosin filament sliding
13.43 1.83e-02 GO:0070252 actin-mediated cell contraction
5.97 1.08e-02 GO:0006936 muscle contraction
5.64 1.69e-02 GO:0007517 muscle organ development
5.47 2.15e-02 GO:0003012 muscle system process
4.87 8.59e-03 GO:0061061 muscle structure development

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
Enrichment   P-value GO Accession GO Term
76.51 4.76e-04 GO:0005862 muscle thin filament tropomyosin
31.39 7.53e-04 GO:0005865 striated muscle thin filament
8.80 3.20e-02 GO:0005604 basement membrane
5.52 2.59e-05 GO:0015629 actin cytoskeleton
4.83 1.31e-04 GO:0031012 extracellular matrix
4.17 1.74e-02 GO:0005578 proteinaceous extracellular matrix
2.08 9.18e-03 GO:0005576 extracellular region

Gene overrepresentation in function category:

Showing 1 to 4 of 4 entries
Enrichment   P-value GO Accession GO Term
25.51 1.50e-04 GO:0005520 insulin-like growth factor binding
8.09 8.03e-04 GO:0019838 growth factor binding
4.15 8.62e-03 GO:0003779 actin binding
3.23 1.29e-02 GO:0008092 cytoskeletal protein binding