Motif ID: NKX2-1,4.p2

Z-value: 1.222


Transcription factors associated with NKX2-1,4.p2:

Gene SymbolEntrez IDGene Name
NKX2-1 7080 NK2 homeobox 1
NKX2-4 644524 NK2 homeobox 4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NKX2-1chr14_-_369889020.332.2e-01Click!


Activity profile for motif NKX2-1,4.p2.

activity profile for motif NKX2-1,4.p2


Sorted Z-values histogram for motif NKX2-1,4.p2

Sorted Z-values for motif NKX2-1,4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NKX2-1,4.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_+_12058963 4.331 NM_001192
 TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chrX_-_154563735 4.007 NM_001289
 CLIC2
chloride intracellular channel 2
chr21_-_15918635 3.648 NM_022136
 SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chrX_+_78200828 3.227 NM_014499
NM_198333
 P2RY10

purinergic receptor P2Y, G-protein coupled, 10

chr11_+_60223281 2.493 NM_021950
NM_152866
 MS4A1

membrane-spanning 4-domains, subfamily A, member 1

chr17_-_29641087 2.278 EVI2B
ecotropic viral integration site 2B
chr1_+_212475147 2.276 NM_001199756
 PPP2R5A
protein phosphatase 2, regulatory subunit B', alpha
chrX_+_48542159 2.200 NM_000377
 WAS
Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
chr17_-_29641094 2.049 NM_006495
 EVI2B
ecotropic viral integration site 2B
chr3_-_141747434 1.635 NM_001178141
NM_001178142
NM_006286
 TFDP2


transcription factor Dp-2 (E2F dimerization partner 2)


chr15_-_55562483 1.625 NM_183234
NM_004580
 RAB27A

RAB27A, member RAS oncogene family

chr5_-_88119604 1.611 NM_001193348
NM_001193349
 MEF2C

myocyte enhancer factor 2C

chrX_-_137821514 1.402 NM_033642
 FGF13
fibroblast growth factor 13
chr2_-_89165652 1.386


chr15_-_55563091 1.371 NM_183236
 RAB27A
RAB27A, member RAS oncogene family
chrX_+_49160124 1.144 NM_001098413
 GAGE10
G antigen 10
chr10_-_11574273 1.143 NM_001080491
 USP6NL
USP6 N-terminal like
chr2_+_33701320 1.132 NM_001139488
 RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr2_+_143886898 1.128 NM_018460
 ARHGAP15
Rho GTPase activating protein 15
chr19_-_6670598 1.049 NM_003807
NM_172014
 TNFSF14

tumor necrosis factor (ligand) superfamily, member 14


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 3 of 3 entries
Enrichment   P-value GO Accession GO Term
19.75 4.34e-04 GO:0046649 lymphocyte activation
18.98 4.62e-05 GO:0045321 leukocyte activation
9.52 2.57e-03 GO:0001775 cell activation

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
Enrichment   P-value GO Accession GO Term
11.38 5.96e-03 GO:0005083 small GTPase regulator activity
6.42 8.05e-04 GO:0030234 enzyme regulator activity