Motif ID: NKX2-3_NKX2-5.p2

Z-value: 1.167


Transcription factors associated with NKX2-3_NKX2-5.p2:

Gene SymbolEntrez IDGene Name
NKX2-3 159296 NK2 transcription factor related, locus 3 (Drosophila)
NKX2-5 1482 NK2 transcription factor related, locus 5 (Drosophila)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NKX2-5chr5_-_172662085-0.391.3e-01Click!


Activity profile for motif NKX2-3_NKX2-5.p2.

activity profile for motif NKX2-3_NKX2-5.p2


Sorted Z-values histogram for motif NKX2-3_NKX2-5.p2

Sorted Z-values for motif NKX2-3_NKX2-5.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NKX2-3_NKX2-5.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_-_56494889 3.519 RNF43
ring finger protein 43
chr7_+_94297448 3.401 PEG10
paternally expressed 10
chr3_-_79817058 2.892 NM_002941
 ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr10_-_105845619 2.820 NM_000494
 COL17A1
collagen, type XVII, alpha 1
chrX_+_105937067 2.645 NM_024539
 RNF128
ring finger protein 128
chr12_-_52886971 2.607 NM_005554
 KRT6A
keratin 6A
chr10_+_7745354 2.545 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr10_+_7745284 2.534 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr4_+_74301932 2.499 NM_001134
 AFP
alpha-fetoprotein
chr3_-_151034514 2.497 NM_023915
 GPR87
G protein-coupled receptor 87
chr19_+_45409003 2.493 NM_000041
 APOE
apolipoprotein E
chr10_+_7745325 2.439 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr10_+_7745341 2.431 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr10_-_105845556 2.405 COL17A1
collagen, type XVII, alpha 1
chrX_+_115567746 2.378 NM_007231
 SLC6A14
solute carrier family 6 (amino acid transporter), member 14
chr12_-_52914080 2.242 NM_000424
 KRT5
keratin 5
chr2_-_31352489 2.186 NM_001253827
 GALNT14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr17_-_64225496 2.082 NM_000042
 APOH
apolipoprotein H (beta-2-glycoprotein I)
chr12_-_28124915 1.919 NM_002820
NM_198965
 PTHLH

parathyroid hormone-like hormone

chr10_+_102123420 1.877



Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

Showing 1 to 3 of 3 entries
Enrichment   P-value GO Accession GO Term
39.22 4.63e-03 GO:0034364 high-density lipoprotein particle
26.97 1.46e-02 GO:0032994 protein-lipid complex
26.97 1.46e-02 GO:0034358 plasma lipoprotein particle

Nothing significant found in function category.