Motif ID: NKX3-1.p2

Z-value: 1.797


Transcription factors associated with NKX3-1.p2:

Gene SymbolEntrez IDGene Name
NKX3-1 4824 NK3 homeobox 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NKX3-1chr8_-_235404010.322.2e-01Click!


Activity profile for motif NKX3-1.p2.

activity profile for motif NKX3-1.p2


Sorted Z-values histogram for motif NKX3-1.p2

Sorted Z-values for motif NKX3-1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NKX3-1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_-_64225496 9.630 NM_000042
 APOH
apolipoprotein H (beta-2-glycoprotein I)
chr7_+_45933096 9.326


chr4_+_74301932 7.676 NM_001134
 AFP
alpha-fetoprotein
chr4_+_88896838 7.187 SPP1
secreted phosphoprotein 1
chr4_+_88896899 7.086 SPP1
secreted phosphoprotein 1
chr4_+_88896868 7.059 SPP1
secreted phosphoprotein 1
chr4_+_88896801 7.055 NM_000582
NM_001040058
NM_001040060
NM_001251829
NM_001251830
 SPP1




secreted phosphoprotein 1




chr4_+_74269971 6.234 NM_000477
 ALB
albumin
chrX_-_131573638 5.156 NM_018388
NM_133486
 MBNL3

muscleblind-like 3 (Drosophila)

chr20_+_30697291 4.906 NM_014742
 TM9SF4
transmembrane 9 superfamily protein member 4
chr17_-_56492938 4.329 RNF43
ring finger protein 43
chr8_-_17743062 3.935 FGL1
fibrinogen-like 1
chr7_+_94539209 3.392 NM_001166161
NM_001166162
NM_001166163
 PPP1R9A


protein phosphatase 1, regulatory subunit 9A


chr12_-_103311380 3.071 NM_000277
 PAH
phenylalanine hydroxylase
chrX_+_107683015 3.056 NM_000495
NM_033380
 COL4A5

collagen, type IV, alpha 5

chr6_+_31895201 2.907 NM_000063
NM_001145903
 C2

complement component 2

chr8_-_17752847 2.884 NM_147203
NM_201553
NM_004467
NM_201552
 FGL1



fibrinogen-like 1



chr5_+_156696351 2.722 NM_014376
 CYFIP2
cytoplasmic FMR1 interacting protein 2
chrX_+_105937067 2.634 NM_024539
 RNF128
ring finger protein 128
chr3_-_149086884 2.612 TM4SF1
transmembrane 4 L six family member 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 1 of 1 entries
Enrichment   P-value GO Accession GO Term
75.30 2.43e-03 GO:0030212 hyaluronan metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 1 of 1 entries
Enrichment   P-value GO Accession GO Term
2.55 1.12e-02 GO:0005576 extracellular region

Gene overrepresentation in function category:

Showing 1 to 4 of 4 entries
Enrichment   P-value GO Accession GO Term
16.21 1.08e-03 GO:0004867 serine-type endopeptidase inhibitor activity
8.90 1.93e-02 GO:0004866 endopeptidase inhibitor activity
8.74 2.10e-02 GO:0030414 peptidase inhibitor activity
8.52 2.36e-02 GO:0061135 endopeptidase regulator activity