Motif ID: NKX6-1,2.p2

Z-value: 1.519


Transcription factors associated with NKX6-1,2.p2:

Gene SymbolEntrez IDGene Name
NKX6-1 4825 NK6 homeobox 1
NKX6-2 84504 NK6 homeobox 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NKX6-1chr4_-_854193860.009.9e-01Click!


Activity profile for motif NKX6-1,2.p2.

activity profile for motif NKX6-1,2.p2


Sorted Z-values histogram for motif NKX6-1,2.p2

Sorted Z-values for motif NKX6-1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NKX6-1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_169418167 6.476 NM_001166108
NM_016081
 PALLD

palladin, cytoskeletal associated protein

chr2_-_238322840 4.649 NM_004369
NM_057164
NM_057165
NM_057166
NM_057167
 COL6A3




collagen, type VI, alpha 3




chr4_+_41258895 4.340 NM_004181
 UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr2_-_175712276 4.086 NM_001206602
 CHN1
chimerin (chimaerin) 1
chr2_-_238322815 3.864 COL6A3
collagen, type VI, alpha 3
chr2_-_151344145 3.836 NM_005168
 RND3
Rho family GTPase 3
chr4_+_55095263 3.830 NM_006206
 PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr12_-_91505541 3.788 NM_002345
 LUM
lumican
chr4_+_41258909 3.532 UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr12_-_91505215 3.400 LUM
lumican
chr3_-_79817058 3.341 NM_002941
 ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr13_-_38172862 3.084 NM_001135934
NM_001135935
NM_001135936
NM_006475
 POSTN



periostin, osteoblast specific factor



chr7_-_137028533 2.678 NM_002825
 PTN
pleiotrophin
chr5_-_111091947 2.623 NM_001142483
 C5orf13
chromosome 5 open reading frame 13
chr21_+_30517897 2.294 C21orf7
chromosome 21 open reading frame 7
chrX_-_10535476 2.289 NM_001193278
NM_001193279
NM_001193280
NM_001193281
 MID1



midline 1 (Opitz/BBB syndrome)



chr9_+_116263706 2.198 NM_130795
 RGS3
regulator of G-protein signaling 3
chr2_-_217560247 2.128 NM_000599
 IGFBP5
insulin-like growth factor binding protein 5
chr20_+_19915716 2.092 RIN2
Ras and Rab interactor 2
chr6_+_114178516 2.077 NM_002356
 MARCKS
myristoylated alanine-rich protein kinase C substrate

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

Showing 1 to 1 of 1 entries
Enrichment   P-value GO Accession GO Term
147.95 3.69e-03 GO:0005589 collagen type VI

Nothing significant found in function category.