Motif ID: NR5A1,2.p2

Z-value: 2.114


Transcription factors associated with NR5A1,2.p2:

Gene SymbolEntrez IDGene Name
NR5A1 2516 nuclear receptor subfamily 5, group A, member 1
NR5A2 2494 nuclear receptor subfamily 5, group A, member 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NR5A2chr1_+_199996729-0.411.2e-01Click!
NR5A1chr9_-_127269689-0.253.6e-01Click!


Activity profile for motif NR5A1,2.p2.

activity profile for motif NR5A1,2.p2


Sorted Z-values histogram for motif NR5A1,2.p2

Sorted Z-values for motif NR5A1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NR5A1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_5275904 8.648 NM_000184
 HBG1
HBG2
hemoglobin, gamma A
hemoglobin, gamma G
chr11_-_5271035 7.841 NM_000559
 HBG1
hemoglobin, gamma A
chr1_-_182354649 2.642 GLUL
glutamate-ammonia ligase
chr1_-_149814264 2.312 NM_001040874
NM_003516
 HIST2H2AA4
HIST2H2AA3
histone cluster 2, H2aa4
histone cluster 2, H2aa3
chr1_+_149822627 2.205 NM_001040874
NM_003516
 HIST2H2AA4
HIST2H2AA3
histone cluster 2, H2aa4
histone cluster 2, H2aa3
chr14_-_103989195 2.155 NM_001823
 CKB
creatine kinase, brain
chrX_+_48644961 2.012 NM_002049
 GATA1
GATA binding protein 1 (globin transcription factor 1)
chr14_-_103989112 1.985 CKB
creatine kinase, brain
chr3_+_69985750 1.938 NM_000248
NM_001184968
NM_198158
NM_198178
 MITF



microphthalmia-associated transcription factor



chr14_-_103988829 1.926 CKB
creatine kinase, brain
chrX_-_151938194 1.736 NM_005362
 MAGEA3
melanoma antigen family A, 3
chr1_+_149858466 1.733 NM_003517
 HIST2H2AC
histone cluster 2, H2ac
chrX_+_30261847 1.701 NM_002363
NM_177415
 MAGEB1

melanoma antigen family B, 1

chr10_+_81107259 1.647 PPIF
peptidylprolyl isomerase F
chrX_+_151867244 1.629 NM_005363
NM_175868
 MAGEA2
MAGEA6

melanoma antigen family A, 2
melanoma antigen family A, 6

chr7_-_150652861 1.618 NM_001204798
NM_172057
 KCNH2

potassium voltage-gated channel, subfamily H (eag-related), member 2

chr10_+_81107242 1.578 PPIF
peptidylprolyl isomerase F
chr5_-_42811959 1.555 NM_001085486
NM_001093726
NM_005410
 SEPP1


selenoprotein P, plasma, 1


chr6_-_125623214 1.536 NM_016063
 HDDC2
HD domain containing 2
chr6_-_125623071 1.523 HDDC2
HD domain containing 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 19 of 19 entries
Enrichment   P-value GO Accession GO Term
34.09 1.40e-11 GO:0006334 nucleosome assembly
33.28 8.92e-13 GO:0034728 nucleosome organization
33.24 1.82e-11 GO:0031497 chromatin assembly
30.54 2.39e-12 GO:0071824 protein-DNA complex subunit organization
29.59 6.09e-11 GO:0065004 protein-DNA complex assembly
25.90 2.40e-10 GO:0006323 DNA packaging
25.32 1.99e-11 GO:0006333 chromatin assembly or disassembly
21.72 1.43e-09 GO:0071103 DNA conformation change
13.82 2.67e-02 GO:0042742 defense response to bacterium
9.73 6.60e-07 GO:0034622 cellular macromolecular complex assembly
8.73 3.83e-07 GO:0006325 chromatin organization
7.84 1.29e-06 GO:0034621 cellular macromolecular complex subunit organization
6.63 8.43e-06 GO:0051276 chromosome organization
5.60 5.32e-05 GO:0065003 macromolecular complex assembly
5.04 5.05e-05 GO:0043933 macromolecular complex subunit organization
4.92 6.63e-04 GO:0071844 cellular component assembly at cellular level
3.80 3.14e-03 GO:0022607 cellular component assembly
3.40 9.66e-03 GO:0044085 cellular component biogenesis
2.80 3.26e-02 GO:0006996 organelle organization

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
Enrichment   P-value GO Accession GO Term
146.81 2.60e-11 GO:0005833 hemoglobin complex
52.79 3.79e-14 GO:0000786 nucleosome
32.06 7.58e-12 GO:0032993 protein-DNA complex
13.21 5.70e-08 GO:0000785 chromatin
11.72 3.54e-04 GO:0044445 cytosolic part
7.05 2.26e-05 GO:0044427 chromosomal part
5.87 1.20e-04 GO:0005694 chromosome

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
Enrichment   P-value GO Accession GO Term
112.15 1.43e-08 GO:0005344 oxygen transporter activity
31.31 1.61e-05 GO:0019825 oxygen binding
14.57 9.47e-05 GO:0020037 heme binding
13.59 1.42e-04 GO:0046906 tetrapyrrole binding
8.61 1.96e-03 GO:0005506 iron ion binding
2.24 4.79e-02 GO:0003677 DNA binding