Motif ID: NR6A1.p2

Z-value: 0.776


Transcription factors associated with NR6A1.p2:

Gene SymbolEntrez IDGene Name
NR6A1 2649 nuclear receptor subfamily 6, group A, member 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NR6A1chr9_-_127533397-0.273.0e-01Click!


Activity profile for motif NR6A1.p2.

activity profile for motif NR6A1.p2


Sorted Z-values histogram for motif NR6A1.p2

Sorted Z-values for motif NR6A1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NR6A1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 101 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_224903324 4.487 NM_001136530
 SERPINE2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr19_-_6720585 2.301 NM_000064
 C3
complement component 3
chr17_-_48264039 2.284 COL1A1
collagen, type I, alpha 1
chr15_+_101420004 2.027 NM_000693
 ALDH1A3
aldehyde dehydrogenase 1 family, member A3
chr7_+_100199881 1.875 NM_002593
 PCOLCE
procollagen C-endopeptidase enhancer
chr1_+_19923457 1.727 NM_001204088
NM_001204089
NM_001032363
NM_001204082
NM_001204083
 C1orf151-NBL1

MINOS1


C1orf151-NBL1 readthrough

mitochondrial inner membrane organizing system 1


chr15_+_101420032 1.398 ALDH1A3
aldehyde dehydrogenase 1 family, member A3
chr16_+_56642477 1.299 NM_005953
 MT2A
metallothionein 2A
chr12_+_7169192 1.051


chr2_-_162930629 1.040 DPP4
dipeptidyl-peptidase 4
chr9_+_124043719 0.912 GSN
gelsolin
chr2_-_162930500 0.837 DPP4
dipeptidyl-peptidase 4
chr7_-_150038689 0.784 NM_002889
 RARRES2
retinoic acid receptor responder (tazarotene induced) 2
chr10_+_123754141 0.700 TACC2
transforming, acidic coiled-coil containing protein 2
chr17_-_27402626 0.602 NM_004740
 TIAF1
TGFB1-induced anti-apoptotic factor 1
chr2_-_162930544 0.581 DPP4
dipeptidyl-peptidase 4
chr3_+_133464883 0.525 NM_001063
 TF
transferrin
chr3_+_46619075 0.424 NM_003212
 TDGF1
teratocarcinoma-derived growth factor 1
chr1_-_153538305 0.420 NM_005978
 S100A2
S100 calcium binding protein A2
chr19_-_15083729 0.407 NM_005071
 SLC1A6
solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 10 of 10 entries
Enrichment   P-value GO Accession GO Term
263.62 1.81e-03 GO:0010953 regulation of protein maturation by peptide bond cleavage
263.62 1.81e-03 GO:0070613 regulation of protein processing
225.98 2.49e-03 GO:0060324 face development
186.12 3.72e-03 GO:0060322 head development
95.94 1.44e-02 GO:0022407 regulation of cell-cell adhesion
67.40 2.93e-02 GO:0007162 negative regulation of cell adhesion
57.62 4.02e-02 GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
56.59 4.17e-02 GO:0002706 regulation of lymphocyte mediated immunity
56.59 4.17e-02 GO:0002819 regulation of adaptive immune response
32.17 5.59e-03 GO:0030155 regulation of cell adhesion

Gene overrepresentation in compartment category:

Showing 1 to 4 of 4 entries
Enrichment   P-value GO Accession GO Term
16.15 1.02e-02 GO:0031012 extracellular matrix
9.63 5.77e-03 GO:0005615 extracellular space
7.68 1.40e-02 GO:0044421 extracellular region part
5.67 7.78e-03 GO:0005576 extracellular region

Gene overrepresentation in function category:

Showing 1 to 9 of 9 entries
Enrichment   P-value GO Accession GO Term
90.47 2.99e-03 GO:0005518 collagen binding
33.29 9.31e-04 GO:0061134 peptidase regulator activity
32.39 2.35e-02 GO:0008201 heparin binding
28.11 3.11e-02 GO:0004866 endopeptidase inhibitor activity
27.62 3.22e-02 GO:0030414 peptidase inhibitor activity
26.92 3.39e-02 GO:0061135 endopeptidase regulator activity
24.83 3.98e-02 GO:0005539 glycosaminoglycan binding
23.04 4.62e-02 GO:0001871 pattern binding
23.04 4.62e-02 GO:0030247 polysaccharide binding