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• Activity deltas table
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Motif ID: ONECUT1,2.p2

Z-value: 1.291

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr6_+_30130982	5.844	NM_033229	TRIM15	tripartite motif containing 15
chr10_+_7745341	3.998		ITIH2	inter-alpha-trypsin inhibitor heavy chain 2
chr10_+_7745354	3.965		ITIH2	inter-alpha-trypsin inhibitor heavy chain 2
chr10_+_7745284	3.884		ITIH2	inter-alpha-trypsin inhibitor heavy chain 2
chr10_+_7745229	3.868	NM_002216	ITIH2	inter-alpha-trypsin inhibitor heavy chain 2
chrX_-_131573638	3.794	NM_018388 NM_133486	MBNL3	muscleblind-like 3 (Drosophila)
chr10_+_7745325	3.778		ITIH2	inter-alpha-trypsin inhibitor heavy chain 2
chr5_-_149792370	3.665	NM_001025158 NM_001025159 NM_004355	CD74	CD74 molecule, major histocompatibility complex, class II invariant chain
chr6_-_41715078	3.277	NM_001166424 NM_002630	PGC	progastricsin (pepsinogen C)
chr5_-_149792276	3.274		CD74	CD74 molecule, major histocompatibility complex, class II invariant chain
chr18_+_29171729	3.095	NM_000371	TTR	transthyretin
chrX_+_46940235	2.984		RGN	regucalcin (senescence marker protein-30)
chr6_+_31895201	2.958	NM_000063 NM_001145903	C2	complement component 2
chr11_+_22696318	2.729	NM_005256	GAS2	growth arrest-specific 2
chr4_-_155511838	2.721	NM_000508 NM_021871	FGA	fibrinogen alpha chain
chr6_+_31913852	2.582		CFB	complement factor B
chr10_-_98031154	2.494	NM_001114094 NM_013314	BLNK	B-cell linker
chr7_+_94297448	2.481		PEG10	paternally expressed 10
chr4_-_69886112	2.464	NM_001075 NM_001144767	UGT2B10	UDP glucuronosyltransferase 2 family, polypeptide B10
chr15_-_60919642	2.336	NM_002943 NM_134260	RORA	RAR-related orphan receptor A
chr3_-_148939784	2.249	NM_000096	CP	ceruloplasmin (ferroxidase)
chr20_-_34241830	2.069	NM_003915	CPNE1	copine I
chr6_+_64286348	1.998		PTP4A1	protein tyrosine phosphatase type IVA, member 1
chr22_+_23054862	1.898		IGLV3-21 IGLJ3 IGLC1	immunoglobulin lambda variable 3-21 immunoglobulin lambda joining 3 immunoglobulin lambda constant 1 (Mcg marker)
chr13_-_46679143	1.728	NM_001872 NM_016413	CPB2	carboxypeptidase B2 (plasma)
chr16_+_69680959	1.672		NFAT5	nuclear factor of activated T-cells 5, tonicity-responsive
chr1_+_111413820	1.622	NM_001040033	CD53	CD53 molecule
chr1_+_198608136	1.612	NM_002838 NM_080921 NM_080923	PTPRC	protein tyrosine phosphatase, receptor type, C
chr4_-_69817478	1.599	NM_024743	UGT2A3	UDP glucuronosyltransferase 2 family, polypeptide A3
chr7_+_45933096	1.589
chr1_+_198608244	1.580		PTPRC	protein tyrosine phosphatase, receptor type, C
chr9_-_123812535	1.548	NM_001735	C5	complement component 5
chr2_-_89165652	1.531
chr1_+_212788359	1.524	NM_001206486	ATF3	activating transcription factor 3
chr4_+_69681709	1.520	NM_001075 NM_001144767	UGT2B10	UDP glucuronosyltransferase 2 family, polypeptide B10
chr14_-_23426356	1.512		HAUS4	HAUS augmin-like complex, subunit 4
chr7_-_100239136	1.454	NM_003227	TFR2	transferrin receptor 2
chr3_-_183273407	1.445	NM_130446	KLHL6	kelch-like 6 (Drosophila)
chr3_-_170744767	1.420	NM_000340	SLC2A2	solute carrier family 2 (facilitated glucose transporter), member 2
chr1_+_198608216	1.388		PTPRC	protein tyrosine phosphatase, receptor type, C
chr17_-_56494930	1.369	NM_017763	RNF43	ring finger protein 43
chr7_+_94292737	1.341		PEG10	paternally expressed 10
chr8_+_123794043	1.325		ZHX2	zinc fingers and homeoboxes 2
chr4_-_70080448	1.300	NM_001073	UGT2B11 UGT2B10	UDP glucuronosyltransferase 2 family, polypeptide B11 UDP glucuronosyltransferase 2 family, polypeptide B10
chr1_+_15990300	1.277
chr5_+_70944968	1.269		MCCC2	methylcrotonoyl-CoA carboxylase 2 (beta)
chr17_-_64225496	1.253	NM_000042	APOH	apolipoprotein H (beta-2-glycoprotein I)
chr19_-_48389514	1.208		SULT2A1	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
chr14_+_39736529	1.206		CTAGE5	CTAGE family, member 5
chr15_-_37391893	1.112		MEIS2	Meis homeobox 2
chr3_-_49459870	1.106		AMT	aminomethyltransferase
chr14_-_23426265	1.093	NM_001166269 NM_001166270 NM_017815	HAUS4	HAUS augmin-like complex, subunit 4
chr7_-_23509972	1.089	NM_006547	IGF2BP3	insulin-like growth factor 2 mRNA binding protein 3
chr10_-_101841593	1.085	NM_001308	CPN1	carboxypeptidase N, polypeptide 1
chr9_+_35673852	1.071	NM_001216	CA9	carbonic anhydrase IX
chrX_-_32430370	1.062	NM_004011 NM_004012	DMD	dystrophin
chr3_-_49460110	1.050	NM_000481 NM_001164710 NM_001164711 NM_001164712	AMT	aminomethyltransferase
chr2_-_88427535	1.041	NM_001443	FABP1	fatty acid binding protein 1, liver
chr13_-_46756295	1.040		LCP1	lymphocyte cytosolic protein 1 (L-plastin)
chr6_+_33043702	0.998	NM_002121	HLA-DPB1	major histocompatibility complex, class II, DP beta 1
chr3_-_105421044	0.987		CBLB	Cas-Br-M (murine) ecotropic retroviral transforming sequence b
chr5_+_68667280	0.971	NM_133339	RAD17	RAD17 homolog (S. pombe)
chr10_-_52645384	0.967		A1CF	APOBEC1 complementation factor
chr6_-_79675672	0.959		PHIP	pleckstrin homology domain interacting protein
chr19_-_39826676	0.941	NM_004877	GMFG	glia maturation factor, gamma
chr10_-_116392099	0.930		ABLIM1	actin binding LIM protein 1
chr11_+_22689653	0.897	NM_177553	GAS2	growth arrest-specific 2
chr12_-_9268440	0.886		A2M	alpha-2-macroglobulin
chr10_+_102732285	0.877	NM_001203244 NM_017893	SEMA4G	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr7_+_120702818	0.871		C7orf58	chromosome 7 open reading frame 58
chrX_-_131547536	0.869	NM_001170701 NM_001170702 NM_001170703	MBNL3	muscleblind-like 3 (Drosophila)
chr10_+_63661012	0.859	NM_032199	ARID5B	AT rich interactive domain 5B (MRF1-like)
chr21_-_43735705	0.843	NM_003226	TFF3	trefoil factor 3 (intestinal)
chr11_+_22688156	0.817	NM_001143830	GAS2	growth arrest-specific 2
chr17_+_72439187	0.797		GPRC5C	G protein-coupled receptor, family C, group 5, member C
chr10_-_52645430	0.779	NM_001198818 NM_001198819 NM_001198820 NM_014576 NM_138932 NM_138933	A1CF	APOBEC1 complementation factor
chr5_+_139876504	0.764		ANKHD1	ankyrin repeat and KH domain containing 1
chr5_+_176516550	0.750	NM_022963	FGFR4	fibroblast growth factor receptor 4
chr17_-_49124128	0.739	NM_001251971	SPAG9	sperm associated antigen 9
chr13_-_46756291	0.738		LCP1	lymphocyte cytosolic protein 1 (L-plastin)
chr3_+_121774208	0.735	NM_001206924 NM_001206925 NM_175862	CD86	CD86 molecule
chr4_-_116034932	0.721	NM_022569	NDST4	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
chr14_-_38064176	0.710		FOXA1	forkhead box A1
chr6_+_74171610	0.706		MTO1	mitochondrial translation optimization 1 homolog (S. cerevisiae)
chr15_-_80263460	0.702	NM_001114735 NM_004049	BCL2A1	BCL2-related protein A1
chr4_+_74301932	0.699	NM_001134	AFP	alpha-fetoprotein
chr13_-_46756326	0.681	NM_002298	LCP1	lymphocyte cytosolic protein 1 (L-plastin)
chr6_-_32920812	0.678	NM_006120	HLA-DMA	major histocompatibility complex, class II, DM alpha
chr6_+_100054649	0.674	NM_021620	PRDM13	PR domain containing 13
chr6_+_56954985	0.672		ZNF451	zinc finger protein 451
chr6_-_41703938	0.661	NM_001167827	TFEB	transcription factor EB
chr4_-_84035888	0.654		PLAC8	placenta-specific 8
chr3_+_12392993	0.652	NM_015869	PPARG	peroxisome proliferator-activated receptor gamma
chr20_+_48552928	0.648		RNF114	ring finger protein 114
chr1_-_51887740	0.644	NM_001159969	EPS15	epidermal growth factor receptor pathway substrate 15
chr6_+_56954978	0.643		ZNF451	zinc finger protein 451
chr5_+_68666861	0.626	NM_133340 NM_133341	RAD17	RAD17 homolog (S. pombe)
chr15_-_65412175	0.625		PDCD7	programmed cell death 7
chr7_+_6617035	0.622	NM_001134387 NM_001134388 NM_001134389 NM_018106	ZDHHC4	zinc finger, DHHC-type containing 4
chr1_-_151431648	0.616		POGZ	pogo transposable element with ZNF domain
chr7_+_94539209	0.610	NM_001166161 NM_001166162 NM_001166163	PPP1R9A	protein phosphatase 1, regulatory subunit 9A
chrX_-_33357725	0.603	NM_000109	DMD	dystrophin
chr12_+_8332789	0.601		FAM66C	family with sequence similarity 66, member C
chr4_+_187187117	0.593	NM_000128	F11	coagulation factor XI
chr8_-_80993009	0.586	NM_001025252	TPD52	tumor protein D52
chr6_+_43738177	0.584		VEGFA	vascular endothelial growth factor A
chr19_-_48389571	0.583	NM_003167	SULT2A1	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
chr20_+_48552902	0.583	NM_018683	RNF114	ring finger protein 114
chr6_+_30227335	0.570		HLA-L	major histocompatibility complex, class I, L, pseudogene
chr18_-_47814691	0.570	NM_001101654 NM_014593	CXXC1	CXXC finger protein 1
chr6_+_56954801	0.568	NM_001031623 NM_015555	ZNF451	zinc finger protein 451
chr20_+_48552935	0.559		RNF114	ring finger protein 114
chrX_-_24690740	0.558	NM_001163264	PCYT1B	phosphate cytidylyltransferase 1, choline, beta
chrX_-_129272014	0.555	NM_001130846	AIFM1	apoptosis-inducing factor, mitochondrion-associated, 1
chr6_+_43738394	0.547		VEGFA	vascular endothelial growth factor A
chr13_-_75901897	0.543		TBC1D4	TBC1 domain family, member 4
chr12_+_54892567	0.540	NM_001184976	NCKAP1L	NCK-associated protein 1-like
chr10_-_42863435	0.534		LOC441666	zinc finger protein 91 pseudogene
chr14_+_21457964	0.533	NM_001029991 NM_022734	METTL17	methyltransferase like 17
chr17_-_38721701	0.528	NM_001838	CCR7	chemokine (C-C motif) receptor 7
chr20_+_32150139	0.511	NM_001039709 NM_005093	CBFA2T2	core-binding factor, runt domain, alpha subunit 2; translocated to, 2
chr3_-_197300193	0.506	NM_203315	BDH1	3-hydroxybutyrate dehydrogenase, type 1
chr2_+_143886969	0.499		ARHGAP15	Rho GTPase activating protein 15
chr2_-_167005641	0.497	NM_001202435	SCN1A	sodium channel, voltage-gated, type I, alpha subunit
chr15_+_74900712	0.494	NM_003992	CLK3	CDC-like kinase 3
chr3_-_178969402	0.492	NM_014407	KCNMB3	potassium large conductance calcium-activated channel, subfamily M beta member 3
chr15_+_93443418	0.489	NM_001042572 NM_001271	CHD2	chromodomain helicase DNA binding protein 2
chr4_-_38806410	0.482	NM_003263	TLR1	toll-like receptor 1
chr16_+_81812897	0.482	NM_002661	PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr4_-_151770611	0.481		LRBA	LPS-responsive vesicle trafficking, beach and anchor containing
chr5_-_98262217	0.480	NM_001270	CHD1	chromodomain helicase DNA binding protein 1
chr19_+_36486042	0.472	NM_001042631	SDHAF1	succinate dehydrogenase complex assembly factor 1
chr2_-_166930130	0.464	NM_001165963 NM_001165964 NM_006920	SCN1A	sodium channel, voltage-gated, type I, alpha subunit
chr6_+_56954889	0.463		ZNF451	zinc finger protein 451
chr6_+_32407618	0.457	NM_019111	HLA-DRA	major histocompatibility complex, class II, DR alpha
chr4_+_187187342	0.453		F11	coagulation factor XI
chr10_+_97471535	0.448	NM_001098175	ENTPD1	ectonucleoside triphosphate diphosphohydrolase 1
chr17_+_7461591	0.437	NM_001198622 NM_001198623 NM_001198624 NM_003808 NM_172087 NM_172088	TNFSF13	tumor necrosis factor (ligand) superfamily, member 13
chr3_-_79817058	0.436	NM_002941	ROBO1	roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr17_-_41623652	0.436	NM_001079675	ETV4	ets variant 4
chr1_-_109935869	0.429	NM_001205228	SORT1	sortilin 1
chr4_-_89978117	0.428	NM_014883	FAM13A	family with sequence similarity 13, member A
chr2_-_172087823	0.418	NM_001136554	TLK1	tousled-like kinase 1
chr22_+_22723972	0.417
chr6_-_133084585	0.409	NM_078488	VNN2	vanin 2
chr13_-_49018802	0.407	NM_005767	LPAR6	lysophosphatidic acid receptor 6
chr14_+_39735500	0.404	NM_001247988 NM_203356	CTAGE5	CTAGE family, member 5
chr2_+_163200582	0.404	NM_012198	GCA	grancalcin, EF-hand calcium binding protein
chr10_+_102123420	0.398
chr5_-_42811959	0.396	NM_001085486 NM_001093726 NM_005410	SEPP1	selenoprotein P, plasma, 1
chr14_-_38064440	0.394	NM_004496	FOXA1	forkhead box A1
chr5_+_159614373	0.388	NM_001130958	FABP6	fatty acid binding protein 6, ileal
chr3_-_12586962	0.387	NM_001195279	LOC100129480	uncharacterized LOC100129480
chr6_-_79787784	0.382		PHIP	pleckstrin homology domain interacting protein
chr1_+_28764660	0.381	NM_023923	PHACTR4	phosphatase and actin regulator 4
chr6_-_44280986	0.379	NM_020745	AARS2	alanyl-tRNA synthetase 2, mitochondrial (putative)
chr6_-_26056647	0.377	NM_005319	HIST1H1C	histone cluster 1, H1c
chr14_+_58894709	0.375	NM_014749	KIAA0586	KIAA0586
chr14_+_39649711	0.371		PNN	pinin, desmosome associated protein
chr18_+_13611664	0.370	NM_001003674 NM_001003675	C18orf1	chromosome 18 open reading frame 1
chr5_+_115898218	0.369
chr2_+_162272619	0.369	NM_006593	TBR1	T-box, brain, 1
chr1_+_212209129	0.369		DTL	denticleless homolog (Drosophila)
chr16_+_69958900	0.365	NM_199424	WWP2	WW domain containing E3 ubiquitin protein ligase 2
chr7_+_26331611	0.350		SNX10	sorting nexin 10
chr2_-_214015053	0.350	NM_016260	IKZF2	IKAROS family zinc finger 2 (Helios)
chr16_+_81812899	0.349		PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr16_+_30064470	0.344		ALDOA	aldolase A, fructose-bisphosphate
chr1_-_894620	0.342		NOC2L	nucleolar complex associated 2 homolog (S. cerevisiae)
chr8_-_103137134	0.342	NM_001040630	NCALD	neurocalcin delta
chr15_+_67000929	0.336	NM_001142861	SMAD6	SMAD family member 6
chr3_+_171561138	0.333	NM_001164436	TMEM212	transmembrane protein 212
chr2_-_20512016	0.331		PUM2	pumilio homolog 2 (Drosophila)
chr4_-_89744154	0.326	NM_001015045	FAM13A	family with sequence similarity 13, member A
chr17_-_29648631	0.325	NM_001003927 NM_014210	EVI2A	ecotropic viral integration site 2A
chr2_+_143886898	0.323	NM_018460	ARHGAP15	Rho GTPase activating protein 15
chr22_-_37098620	0.322	NM_006078	CACNG2	calcium channel, voltage-dependent, gamma subunit 2
chrX_+_107288199	0.321	NM_001170553 NM_182607	VSIG1	V-set and immunoglobulin domain containing 1
chrX_-_33229428	0.320	NM_004006	DMD	dystrophin
chr8_-_30585442	0.320	NM_000637 NM_001195102 NM_001195103 NM_001195104	GSR	glutathione reductase
chr6_-_27799304	0.318	NM_003541	HIST1H4A HIST1H4F HIST1H4K HIST1H4J	histone cluster 1, H4a histone cluster 1, H4f histone cluster 1, H4k histone cluster 1, H4j
chrX_-_102319080	0.318		BEX1	brain expressed, X-linked 1
chr7_+_102023016	0.317
chr2_+_128928040	0.316		UGGT1	UDP-glucose glycoprotein glucosyltransferase 1
chr5_+_69321071	0.316	NM_001178087 NM_022978 NM_021967 NM_022968	SERF1B SERF1A	small EDRK-rich factor 1B (centromeric) small EDRK-rich factor 1A (telomeric)
chr2_+_86333304	0.315	NM_017952	PTCD3	Pentatricopeptide repeat domain 3
chr3_+_142375738	0.314	NM_001172312	PLS1	plastin 1
chr16_+_30064410	0.314	NM_000034	ALDOA	aldolase A, fructose-bisphosphate
chrX_-_102319096	0.313	NM_018476	BEX1	brain expressed, X-linked 1
chr9_-_70490164	0.311	NM_001024916 NM_201453	CBWD5 CBWD3	COBW domain containing 5 COBW domain containing 3
chr20_-_48530275	0.309	NM_001135773	SPATA2	spermatogenesis associated 2
chr15_-_51630735	0.306	NM_000103 NM_031226	CYP19A1	cytochrome P450, family 19, subfamily A, polypeptide 1
chr4_-_84035908	0.304	NM_001130715 NM_016619	PLAC8	placenta-specific 8
chr10_-_7682741	0.303		ITIH5	inter-alpha-trypsin inhibitor heavy chain family, member 5
chr3_+_9476506	0.302
chr7_-_25268057	0.300	NM_022150	NPVF	neuropeptide VF precursor
chr18_+_55888750	0.294	NM_001144966	NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr2_+_177028804	0.293	NM_006898	HOXD3	homeobox D3
chr12_+_1017011	0.291		WNK1	WNK lysine deficient protein kinase 1
chr3_+_141043054	0.286	NM_001080412	ZBTB38	zinc finger and BTB domain containing 38

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
15.62	8.46e-05	GO:0002252	immune effector process
23.98	6.12e-04	GO:0072376	protein activation cascade
20.56	1.32e-03	GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
19.98	1.52e-03	GO:0002250	adaptive immune response
18.22	2.41e-03	GO:0006959	humoral immune response
28.07	3.83e-03	GO:0006956	complement activation
22.13	9.96e-03	GO:0016064	immunoglobulin mediated immune response
21.72	1.07e-02	GO:0019724	B cell mediated immunity
18.27	2.13e-02	GO:0002449	lymphocyte mediated immunity
8.48	2.20e-02	GO:0002253	activation of immune response
28.77	4.95e-02	GO:0006958	complement activation, classical pathway

Nothing significant found in compartment category.

Nothing significant found in function category.