Motif ID: PDX1.p2

Z-value: 0.589


Transcription factors associated with PDX1.p2:

Gene SymbolEntrez IDGene Name
PDX1 3651 pancreatic and duodenal homeobox 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
PDX1chr13_+_284941360.312.5e-01Click!


Activity profile for motif PDX1.p2.

activity profile for motif PDX1.p2


Sorted Z-values histogram for motif PDX1.p2

Sorted Z-values for motif PDX1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PDX1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_22696318 1.573 NM_005256
GAS2
growth arrest-specific 2
chr18_+_55888799 1.332 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr10_+_63808968 1.273 NM_001244638
ARID5B
AT rich interactive domain 5B (MRF1-like)
chr8_-_17579729 1.212 NM_001001931
MTUS1
microtubule associated tumor suppressor 1
chr8_-_17580024 1.134 NM_001166393
MTUS1
microtubule associated tumor suppressor 1
chr4_+_74281884 1.102 ALB
albumin
chr17_-_7082654 0.924 NM_001197216
NM_001671
ASGR1

asialoglycoprotein receptor 1

chrX_-_131547536 0.890 NM_001170701
NM_001170702
NM_001170703
MBNL3


muscleblind-like 3 (Drosophila)


chr6_-_133035180 0.882 NM_004666
VNN1
vanin 1
chr18_+_55888750 0.803 NM_001144966
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr16_+_70557724 0.803 SF3B3
splicing factor 3b, subunit 3, 130kDa
chr8_-_17555158 0.750 NM_020749
MTUS1
microtubule associated tumor suppressor 1
chr3_+_100238063 0.744 TMEM45A
transmembrane protein 45A
chr16_+_70557726 0.704 SF3B3
splicing factor 3b, subunit 3, 130kDa
chr4_+_88896801 0.694 NM_000582
NM_001040058
NM_001040060
NM_001251829
NM_001251830
SPP1




secreted phosphoprotein 1




chr18_+_55888838 0.629 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr3_+_46619075 0.580 NM_003212
TDGF1
teratocarcinoma-derived growth factor 1
chr16_+_19078958 0.544 COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr2_-_188419049 0.473 TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr3_-_120400957 0.428 HGD
homogentisate 1,2-dioxygenase
chr2_-_188419185 0.359 NM_001032281
NM_006287
TFPI

tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)

chr16_+_8814567 0.355 NM_001127448
ABAT
4-aminobutyrate aminotransferase
chr16_+_19078916 0.341 NM_016138
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr12_-_103311380 0.338 NM_000277
PAH
phenylalanine hydroxylase
chr6_+_167704802 0.325 NM_001143947
NM_018974
UNC93A

unc-93 homolog A (C. elegans)

chr21_-_46348633 0.312 NM_001127491
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr3_+_52813936 0.306 NM_001166435
NM_001166436
ITIH1

inter-alpha-trypsin inhibitor heavy chain 1

chr6_-_134498973 0.296 NM_001143677
SGK1
serum/glucocorticoid regulated kinase 1
chr8_-_80993009 0.291 NM_001025252
TPD52
tumor protein D52
chr2_-_216259197 0.273 FN1
fibronectin 1
chr16_+_19079220 0.267 NM_001190983
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr6_-_131291480 0.238 NM_001199389
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr7_-_87342569 0.234 NM_000927
ABCB1
ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr6_+_33043702 0.228 NM_002121
HLA-DPB1
major histocompatibility complex, class II, DP beta 1
chr4_+_187187342 0.222 F11
coagulation factor XI
chr10_+_88730497 0.215 NM_133447
AGAP11
ankyrin repeat and GTPase domain Arf GTPase activating protein 11
chr19_-_7766978 0.206 NM_001220500
NM_002002
FCER2

Fc fragment of IgE, low affinity II, receptor for (CD23)

chr12_+_51318515 0.204 NM_014033
METTL7A
methyltransferase like 7A
chr16_-_28620648 0.187 NM_177530
NM_177534
SULT1A1

sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1

chr7_+_26400503 0.184 NM_001199837
SNX10
sorting nexin 10
chr3_-_21792815 0.181 NM_024697
ZNF385D
zinc finger protein 385D
chr6_-_143266283 0.176 NM_006734
HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
chr4_-_10023094 0.166 NM_020041
SLC2A9
solute carrier family 2 (facilitated glucose transporter), member 9
chr6_+_158733691 0.158 NM_001007466
NM_020245
TULP4

tubby like protein 4

chr2_+_38893051 0.137 NM_138801
GALM
galactose mutarotase (aldose 1-epimerase)
chr17_+_7960201 0.132


chr2_+_38893238 0.130 GALM
galactose mutarotase (aldose 1-epimerase)
chr5_-_16738346 0.119 MYO10
myosin X
chr6_+_144612872 0.105 NM_007124
UTRN
utrophin
chr6_-_31107110 0.102 NM_014069
PSORS1C2
psoriasis susceptibility 1 candidate 2
chr6_+_35310399 0.102 PPARD
peroxisome proliferator-activated receptor delta
chr1_+_17906941 0.097 NM_001011722
ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr1_+_57320442 0.093 NM_000562
C8A
complement component 8, alpha polypeptide
chr1_+_28764660 0.093 NM_023923
PHACTR4
phosphatase and actin regulator 4
chr6_-_43423785 0.091 NM_206539
DLK2
delta-like 2 homolog (Drosophila)
chr12_-_54020081 0.090 NM_001130060
NM_001206682
NM_006856
ATF7


activating transcription factor 7


chr7_-_44580857 0.088 NM_001101648
NM_013389
NPC1L1

NPC1 (Niemann-Pick disease, type C1, gene)-like 1

chr3_+_52811601 0.086 NM_002215
ITIH1
inter-alpha-trypsin inhibitor heavy chain 1
chr3_+_148447966 0.085 NM_032049
AGTR1
angiotensin II receptor, type 1
chr3_-_178969644 0.081 NM_171830
KCNMB3
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr3_-_114478117 0.080 NM_001164344
NM_001164345
ZBTB20

zinc finger and BTB domain containing 20

chr17_+_7482938 0.077 CD68
CD68 molecule
chr17_+_7482804 0.074 NM_001251
NM_001040059
CD68

CD68 molecule

chr3_-_114343791 0.073 NM_001164346
ZBTB20
zinc finger and BTB domain containing 20
chr16_-_67517715 0.069 NM_001138
AGRP
agouti related protein homolog (mouse)
chr12_-_91398744 0.067 EPYC
epiphycan
chr3_-_47933997 0.065 MAP4
microtubule-associated protein 4
chr16_+_28505920 0.063 NM_018690
APOBR
apolipoprotein B receptor
chr6_-_46825942 0.063 GPR116
G protein-coupled receptor 116
chr12_-_91398757 0.062 NM_004950
EPYC
epiphycan
chr17_-_42144001 0.057 LSM12
LSM12 homolog (S. cerevisiae)
chr2_-_200213802 0.054 SATB2
SATB homeobox 2
chr11_-_66445318 0.053 RBM4B
RNA binding motif protein 4B
chr14_+_23789396 0.051 NM_004643
PABPN1
poly(A) binding protein, nuclear 1
chr6_+_167536240 0.048 NM_031409
CCR6
chemokine (C-C motif) receptor 6
chr14_-_23504353 0.048 NM_001144932
NM_002797
NM_001130725
PSMB5


proteasome (prosome, macropain) subunit, beta type, 5


chr16_+_70557688 0.047 NM_012426
SF3B3
splicing factor 3b, subunit 3, 130kDa
chr1_-_33841142 0.046 NM_198040
PHC2
polyhomeotic homolog 2 (Drosophila)
chr1_+_101003692 0.045 NM_022049
GPR88
G protein-coupled receptor 88
chr6_-_131321868 0.045 NM_001252660
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr4_-_139163222 0.044 NM_014331
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr3_+_151531860 0.042 NM_001086
AADAC
arylacetamide deacetylase (esterase)
chr17_+_7482980 0.042 CD68
CD68 molecule
chr2_-_96947640 0.040 SNRNP200
small nuclear ribonucleoprotein 200kDa (U5)
chr4_+_74606222 0.039 NM_000584
IL8
interleukin 8
chr18_+_616671 0.038 NM_199167
CLUL1
clusterin-like 1 (retinal)
chr2_+_113735595 0.037 NM_019618
IL36G
interleukin 36, gamma
chr1_-_16763887 0.037 NM_198546
SPATA21
spermatogenesis associated 21
chr2_-_218808705 0.037 NM_022648
TNS1
tensin 1
chr6_+_131571298 0.036 NM_004842
NM_138633
AKAP7

A kinase (PRKA) anchor protein 7

chr17_-_29641087 0.036 EVI2B
ecotropic viral integration site 2B
chr17_-_42143937 0.036 LSM12
LSM12 homolog (S. cerevisiae)
chr1_+_79086087 0.033 NM_006820
IFI44L
interferon-induced protein 44-like
chr8_-_20040612 0.032 NM_001135691
NM_001142324
NM_001142325
NM_003053
SLC18A1



solute carrier family 18 (vesicular monoamine), member 1



chr12_+_4699243 0.032 NM_003845
DYRK4
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
chr17_+_39555993 0.032 GAST
gastrin
chrX_+_49091931 0.031 CCDC22
coiled-coil domain containing 22
chr6_+_72926144 0.031 NM_001168409
RIMS1
regulating synaptic membrane exocytosis 1
chr5_-_77844975 0.029 LHFPL2
lipoma HMGIC fusion partner-like 2
chr6_-_62995852 0.029 NM_152688
KHDRBS2
KH domain containing, RNA binding, signal transduction associated 2
chr17_-_42144986 0.028 NM_152344
LSM12
LSM12 homolog (S. cerevisiae)
chr2_+_228192227 0.028 NM_020194
MFF
mitochondrial fission factor
chr17_-_29641068 0.027 EVI2B
ecotropic viral integration site 2B
chr10_+_70980058 0.026 NM_025130
HKDC1
hexokinase domain containing 1
chr16_-_71782165 0.025 AP1G1
adaptor-related protein complex 1, gamma 1 subunit
chr4_-_48136245 0.025 NM_003328
TXK
TXK tyrosine kinase
chr5_-_75919051 0.025 NM_004101
F2RL2
coagulation factor II (thrombin) receptor-like 2
chr11_+_28131830 0.025 METTL15
methyltransferase like 15
chrX_-_62780748 0.023 LOC92249
uncharacterized LOC92249
chr1_+_36748164 0.019 THRAP3
thyroid hormone receptor associated protein 3
chr2_-_47134945 0.019 MCFD2
multiple coagulation factor deficiency 2
chr6_-_41254392 0.019 NM_001242589
NM_001242590
NM_018643
TREM1


triggering receptor expressed on myeloid cells 1


chr17_-_29641094 0.018 NM_006495
EVI2B
ecotropic viral integration site 2B
chr14_+_70918873 0.018 NM_003813
ADAM21
ADAM metallopeptidase domain 21
chr6_-_55740358 0.018 NM_021073
BMP5
bone morphogenetic protein 5
chr1_-_161519817 0.017 NM_000569
NM_001127592
FCGR3A

Fc fragment of IgG, low affinity IIIa, receptor (CD16a)

chr12_-_10962673 0.016 NM_023917
TAS2R9
taste receptor, type 2, member 9
chr4_+_88720701 0.015 NM_004967
IBSP
integrin-binding sialoprotein
chr3_-_123339423 0.015 NM_053031
NM_053032
MYLK

myosin light chain kinase

chr6_-_32731266 0.014 NM_001198858
HLA-DQB2
major histocompatibility complex, class II, DQ beta 2
chr6_+_46761093 0.013 NM_005588
MEP1A
meprin A, alpha (PABA peptide hydrolase)
chr4_-_46996423 0.012 NM_000809
GABRA4
gamma-aminobutyric acid (GABA) A receptor, alpha 4
chr1_+_186265404 0.010 NM_001127708
NM_001127709
NM_001127710
NM_005807
PRG4



proteoglycan 4



chr7_-_113559048 0.009 NM_002711
PPP1R3A
protein phosphatase 1, regulatory subunit 3A
chr1_-_204135420 0.008 NM_000537
REN
renin
chr12_+_15475190 0.008 NM_002848
NM_030667
PTPRO

protein tyrosine phosphatase, receptor type, O

chr19_-_14952688 0.008 NM_001005190
OR7A10
olfactory receptor, family 7, subfamily A, member 10
chr1_+_92632608 0.007 NM_015237
KIAA1107
KIAA1107
chr1_+_12977444 0.006 NM_001012277
PRAMEF7
PRAME family member 7
chr4_+_78432905 0.005 NM_006419
CXCL13
chemokine (C-X-C motif) ligand 13
chr4_-_176733901 0.001 GPM6A
glycoprotein M6A
chr21_-_31538970 0.000 NM_012131
CLDN17
claudin 17

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.