Motif ID: POU1F1.p2

Z-value: 1.405


Transcription factors associated with POU1F1.p2:

Gene SymbolEntrez IDGene Name
POU1F1 5449 POU class 1 homeobox 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
POU1F1chr3_-_87325611-0.224.0e-01Click!


Activity profile for motif POU1F1.p2.

activity profile for motif POU1F1.p2


Sorted Z-values histogram for motif POU1F1.p2

Sorted Z-values for motif POU1F1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU1F1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_74270832 6.301 ALB
albumin
chr2_-_88427535 3.773 NM_001443
 FABP1
fatty acid binding protein 1, liver
chr4_+_69681709 3.648 NM_001075
NM_001144767
 UGT2B10

UDP glucuronosyltransferase 2 family, polypeptide B10

chr4_+_74281884 3.630 ALB
albumin
chr4_+_74269971 3.562 NM_000477
 ALB
albumin
chr4_-_110723334 3.486 NM_000204
 CFI
complement factor I
chr2_-_21225640 3.000 APOB
apolipoprotein B (including Ag(x) antigen)
chr19_-_48389514 2.872 SULT2A1
sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
chr8_-_17752847 2.817 NM_147203
NM_201553
NM_004467
NM_201552
 FGL1



fibrinogen-like 1



chrX_-_2882288 2.692 NM_000047
 ARSE
arylsulfatase E (chondrodysplasia punctata 1)
chr4_-_70080448 2.483 NM_001073
 UGT2B11
UGT2B10
UDP glucuronosyltransferase 2 family, polypeptide B11
UDP glucuronosyltransferase 2 family, polypeptide B10
chr7_+_26400503 2.476 NM_001199837
 SNX10
sorting nexin 10
chr16_+_82068910 2.450 HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr4_+_74301932 2.354 NM_001134
 AFP
alpha-fetoprotein
chr16_+_82068830 2.319 NM_002153
 HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr12_+_100867739 2.063 NR1H4
nuclear receptor subfamily 1, group H, member 4
chr4_+_155484131 1.988 NM_001184741
NM_005141
 FGB

fibrinogen beta chain

chr1_-_169555624 1.826 F5
coagulation factor V (proaccelerin, labile factor)
chr9_-_123812535 1.758 NM_001735
 C5
complement component 5
chr13_-_48987247 1.722 LPAR6
lysophosphatidic acid receptor 6

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 13 of 13 entries
Enrichment   P-value GO Accession GO Term
187.40 1.26e-02 GO:0030573 bile acid catabolic process
52.72 7.63e-03 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
32.14 2.22e-03 GO:0008206 bile acid metabolic process
18.45 2.07e-02 GO:0060333 interferon-gamma-mediated signaling pathway
16.80 3.00e-02 GO:0071346 cellular response to interferon-gamma
10.78 1.92e-04 GO:0008202 steroid metabolic process
9.67 2.18e-03 GO:0002253 activation of immune response
7.65 1.00e-02 GO:0050778 positive regulation of immune response
7.14 4.16e-03 GO:0045087 innate immune response
5.33 4.31e-05 GO:0006629 lipid metabolic process
5.27 4.80e-04 GO:0006955 immune response
3.81 2.44e-03 GO:0002376 immune system process
1.79 2.63e-02 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 8 of 8 entries
Enrichment   P-value GO Accession GO Term
80.33 2.07e-02 GO:0005577 fibrinogen complex
60.25 1.18e-03 GO:0042613 MHC class II protein complex
28.13 1.27e-02 GO:0042611 MHC protein complex
21.64 2.61e-03 GO:0031983 vesicle lumen
17.96 4.86e-02 GO:0031093 platelet alpha granule lumen
4.25 6.51e-03 GO:0005615 extracellular space
3.38 4.24e-02 GO:0044421 extracellular region part
2.78 1.98e-02 GO:0005576 extracellular region

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
Enrichment   P-value GO Accession GO Term
105.42 1.49e-04 GO:0032395 MHC class II receptor activity
6.23 2.12e-03 GO:0008289 lipid binding