Motif ID: POU2F1..3.p2

Z-value: 3.968


Transcription factors associated with POU2F1..3.p2:

Gene SymbolEntrez IDGene Name
POU2F1 5451 POU class 2 homeobox 1
POU2F2 5452 POU class 2 homeobox 2
POU2F3 25833 POU class 2 homeobox 3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
POU2F2chr19_-_426365590.721.7e-03Click!
POU2F1chr1_+_1671899480.562.3e-02Click!
POU2F3chr11_+_120107348,
chr11_+_120110902		0.332.1e-01Click!


Activity profile for motif POU2F1..3.p2.

activity profile for motif POU2F1..3.p2


Sorted Z-values histogram for motif POU2F1..3.p2

Sorted Z-values for motif POU2F1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU2F1..3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_+_23847321 31.453 PRKCB
protein kinase C, beta
chr16_+_23847359 29.005 PRKCB
protein kinase C, beta
chr16_+_23847271 27.415 NM_002738
NM_212535
 PRKCB

protein kinase C, beta

chr14_-_107013474 24.230 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr14_-_106926393 18.078 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr14_-_106573348 15.330 IGHV4-31
IGHA1
IGHA2
IGHG1
IGHG3
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
chr22_+_22758538 14.549


chr22_+_22735134 14.447 CYAT1
immunoglobulin lambda light chain-like
chr14_-_107113943 14.053 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr22_+_23040394 12.058 IGL@
immunoglobulin lambda locus
chr22_+_23165273 11.562


chr10_-_98031154 11.056 NM_001114094
NM_013314
 BLNK

B-cell linker

chr14_-_106518424 10.937 IGH@
IGHA1
IGHG1
IGHG2
IGHM
immunoglobulin heavy locus
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 2 (G2m marker)
immunoglobulin heavy constant mu
chr14_-_106994001 10.870 IGHV3-48
IGH@
IGHA1
IGHM
immunoglobulin heavy variable 3-48
immunoglobulin heavy locus
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant mu
chrX_-_48776282 10.827 NM_006875
 PIM2
pim-2 oncogene
chr14_-_106610338 10.649 IGHV4-31
IGHG1
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant gamma 1 (G1m marker)
chr22_+_22735207 10.436 IGLJ3
immunoglobulin lambda joining 3
chr8_+_56792399 10.105 LYN
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr6_+_12717036 9.957 NM_001242648
NM_030948
 PHACTR1

phosphatase and actin regulator 1

chr14_-_106725620 9.604 IGHV4-31
IGHV3-23
IGHA1
IGHG1
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy variable 3-23
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 28 entries
Enrichment   P-value GO Accession GO Term
26.47 2.81e-21 GO:0006334 nucleosome assembly
25.82 4.90e-21 GO:0031497 chromatin assembly
24.67 9.84e-22 GO:0034728 nucleosome organization
24.60 7.72e-03 GO:0050853 B cell receptor signaling pathway
22.98 6.34e-20 GO:0065004 protein-DNA complex assembly
22.64 7.12e-21 GO:0071824 protein-DNA complex subunit organization
20.11 1.13e-18 GO:0006323 DNA packaging
18.77 4.83e-19 GO:0006333 chromatin assembly or disassembly
17.71 1.75e-18 GO:0071103 DNA conformation change
9.66 1.47e-02 GO:0042113 B cell activation
7.95 4.45e-02 GO:0006959 humoral immune response
7.21 2.25e-10 GO:0034622 cellular macromolecular complex assembly
6.77 1.51e-11 GO:0006325 chromatin organization
5.83 1.28e-09 GO:0034621 cellular macromolecular complex subunit organization
5.35 8.24e-10 GO:0051276 chromosome organization
5.13 9.29e-03 GO:0002253 activation of immune response
4.46 1.28e-02 GO:0050778 positive regulation of immune response
4.40 9.09e-09 GO:0006955 immune response
4.16 1.09e-06 GO:0065003 macromolecular complex assembly
3.99 2.45e-06 GO:0071844 cellular component assembly at cellular level

Gene overrepresentation in compartment category:

Showing 1 to 9 of 9 entries
Enrichment   P-value GO Accession GO Term
41.00 2.08e-26 GO:0000786 nucleosome
24.90 2.27e-21 GO:0032993 protein-DNA complex
12.31 3.12e-18 GO:0000785 chromatin
6.83 6.76e-13 GO:0044427 chromosomal part
5.69 4.37e-11 GO:0005694 chromosome
1.71 4.09e-02 GO:0043228 non-membrane-bounded organelle
1.71 4.09e-02 GO:0043232 intracellular non-membrane-bounded organelle
1.59 3.26e-02 GO:0032991 macromolecular complex
1.45 1.44e-02 GO:0005634 nucleus

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
Enrichment   P-value GO Accession GO Term
26.14 2.02e-10 GO:0003823 antigen binding
2.22 6.85e-05 GO:0003677 DNA binding
1.81 1.35e-03 GO:0003676 nucleic acid binding