Motif ID: POU5F1.p2

Z-value: 2.077


Transcription factors associated with POU5F1.p2:

Gene SymbolEntrez IDGene Name
POU5F1 5460 POU class 5 homeobox 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
POU5F1chr6_-_311346140.351.8e-01Click!


Activity profile for motif POU5F1.p2.

activity profile for motif POU5F1.p2


Sorted Z-values histogram for motif POU5F1.p2

Sorted Z-values for motif POU5F1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU5F1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_67410825 7.988 NM_002758
MAP2K6
mitogen-activated protein kinase kinase 6
chr10_-_98031154 7.774 NM_001114094
NM_013314
BLNK

B-cell linker

chr14_-_106733392 6.011 IGHG1
IGHG3
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
chr22_+_22697538 5.672


chr22_+_23213671 5.551 IGLV4-3
immunoglobulin lambda variable 4-3
chr10_+_11207053 5.476 CELF2
CUGBP, Elav-like family member 2
chr10_+_11206928 5.364 NM_001025076
NM_001083591
CELF2

CUGBP, Elav-like family member 2

chr15_-_80263460 5.252 NM_001114735
NM_004049
BCL2A1

BCL2-related protein A1

chr22_+_22735134 5.201 CYAT1
immunoglobulin lambda light chain-like
chr22_+_22758538 5.129


chr14_-_107179043 4.854 IGHA1
immunoglobulin heavy constant alpha 1
chr22_+_23010757 4.742


chr14_-_107066061 4.654 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr14_-_106405633 4.468 IGHM
immunoglobulin heavy constant mu
chr22_+_23040394 4.380 IGL@
immunoglobulin lambda locus
chr16_+_23847321 4.365 PRKCB
protein kinase C, beta
chr6_+_12717036 4.330 NM_001242648
NM_030948
PHACTR1

phosphatase and actin regulator 1

chr14_-_107131217 4.208 IGHA1
immunoglobulin heavy constant alpha 1
chr22_+_23134980 4.143


chr14_-_107013474 4.105 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr22_+_23165273 4.054


chr4_-_71532206 4.039 IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr7_-_37024664 4.035 NM_001039459
ELMO1
engulfment and cell motility 1
chr19_-_39108534 3.992 NM_001042600
NM_007181
MAP4K1

mitogen-activated protein kinase kinase kinase kinase 1

chr14_-_106691698 3.962


chr2_+_89185055 3.923


chr16_+_23847271 3.867 NM_002738
NM_212535
PRKCB

protein kinase C, beta

chr16_+_23847359 3.830 PRKCB
protein kinase C, beta
chr22_+_22735207 3.686 IGLJ3
immunoglobulin lambda joining 3
chr14_-_106746056 3.678


chr2_-_89442551 3.529 IGKC
IGK@
immunoglobulin kappa constant
immunoglobulin kappa locus
chr22_+_22550112 3.409


chr4_-_71532341 3.204 NM_144646
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr6_-_154651214 3.118 NM_001130699
IPCEF1
interaction protein for cytohesin exchange factors 1
chr22_+_22712091 3.104 IGLV1-44
IGL@
immunoglobulin lambda variable 1-44
immunoglobulin lambda locus
chr14_-_107048697 3.030 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr1_-_31230673 3.012 NM_006762
LAPTM5
lysosomal protein transmembrane 5
chr22_+_22786283 2.801


chr12_+_113344738 2.766 NM_001032409
NM_002534
NM_016816
OAS1


2'-5'-oligoadenylate synthetase 1, 40/46kDa


chr6_-_32908583 2.745 NM_002118
HLA-DMB
major histocompatibility complex, class II, DM beta
chr14_-_106573348 2.672 IGHV4-31
IGHA1
IGHA2
IGHG1
IGHG3
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
chr14_-_106641585 2.660 IGHV4-31
IGHA1
IGHA2
IGHG1
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
chr18_-_53089722 2.550 NM_001243233
TCF4
transcription factor 4
chr14_-_107113943 2.521 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr5_-_142783975 2.500 NM_001018076
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr5_-_88119604 2.494 NM_001193348
NM_001193349
MEF2C

myocyte enhancer factor 2C

chr14_-_106967528 2.487 IGHA1
IGHA2
IGHG1
IGHM
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chr14_-_107170400 2.432 IGHV4-31
IGHV1-69
IGHA1
IGHG1
IGHG3
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy variable 1-69
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
chr6_-_32557431 2.368 NM_001243965
NM_002124
HLA-DRB1

HLA-DRB4
HLA-DRB5
major histocompatibility complex, class II, DR beta 1

major histocompatibility complex, class II, DR beta 4
major histocompatibility complex, class II, DR beta 5
chr10_-_64578926 2.354 NM_001136178
EGR2
early growth response 2
chr9_+_100263461 2.344 NM_001166116
TMOD1
tropomodulin 1
chr8_-_102803196 2.323 NCALD
neurocalcin delta
chrX_-_33357725 2.317 NM_000109
DMD
dystrophin
chr1_-_154832187 2.278 NM_170782
KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr1_-_160681552 2.254 NM_001778
CD48
CD48 molecule
chr5_-_111091947 2.248 NM_001142483
C5orf13
chromosome 5 open reading frame 13
chr10_-_64576123 2.244 NM_000399
NM_001136177
NM_001136179
EGR2


early growth response 2


chr10_-_64576074 2.221 EGR2
early growth response 2
chr22_+_22550159 2.167 IGLV6-57
immunoglobulin lambda variable 6-57
chr12_+_25205180 2.154 NM_001204126
NM_001204127
NM_006152
LRMP


lymphoid-restricted membrane protein


chr12_-_8765438 2.120 NM_020661
AICDA
activation-induced cytidine deaminase
chr2_+_68592317 2.111 NM_002664
PLEK
pleckstrin
chr13_-_99959649 2.078 NM_004951
GPR183
G protein-coupled receptor 183
chr5_+_49962771 2.028 NM_001178056
NM_024615
PARP8

poly (ADP-ribose) polymerase family, member 8

chr1_-_23885916 2.015 ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr14_+_64682671 1.961 NM_182910
SYNE2
spectrin repeat containing, nuclear envelope 2
chr7_+_116660291 1.944 ST7
suppression of tumorigenicity 7
chr14_-_106692107 1.939 IGHV4-31
IGHA1
IGHD
IGHG1
IGHG3
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
chr14_-_106610338 1.926 IGHV4-31
IGHG1
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant gamma 1 (G1m marker)
chr20_+_9494995 1.923 NM_001199897
NM_012261
LAMP5

lysosomal-associated membrane protein family, member 5

chrX_+_154611748 1.912 NM_001007523
NM_001007524
NM_012151
F8A2
F8A3
F8A1
coagulation factor VIII-associated 2
coagulation factor VIII-associated 3
coagulation factor VIII-associated 1
chr14_-_106926393 1.903 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr12_+_25205488 1.878 LRMP
lymphoid-restricted membrane protein
chr3_-_127541160 1.825 NM_007283
MGLL
monoglyceride lipase
chr14_-_106494166 1.812 IGHV4-31
IGHA1
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
chr22_+_22676814 1.809


chr1_+_167298280 1.798 NM_001198783
POU2F1
POU class 2 homeobox 1
chr14_-_106725620 1.793 IGHV4-31
IGHV3-23
IGHA1
IGHG1
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy variable 3-23
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chr17_-_62009620 1.789 NM_000626
NM_001039933
NM_021602
CD79B


CD79b molecule, immunoglobulin-associated beta


chr5_-_88179278 1.785 NM_001193350
NM_002397
MEF2C

myocyte enhancer factor 2C

chr14_-_106994001 1.783 IGHV3-48
IGH@
IGHA1
IGHM
immunoglobulin heavy variable 3-48
immunoglobulin heavy locus
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant mu
chr1_+_192544856 1.780 NM_002922
RGS1
regulator of G-protein signaling 1
chr17_-_40833840 1.751 NM_016602
CCR10
chemokine (C-C motif) receptor 10
chr3_-_16555128 1.744 NM_015150
RFTN1
raftlin, lipid raft linker 1
chr8_-_102803178 1.732 NCALD
neurocalcin delta
chr3_+_98250742 1.690 NM_005290
GPR15
G protein-coupled receptor 15
chr6_-_24877453 1.678 NM_015864
FAM65B
family with sequence similarity 65, member B
chr1_+_167298382 1.662 POU2F1
POU class 2 homeobox 1
chr4_-_153273683 1.658 NM_018315
FBXW7
F-box and WD repeat domain containing 7
chr6_-_29527477 1.643 UBD
ubiquitin D
chr11_+_58939960 1.636 DTX4
deltex homolog 4 (Drosophila)
chr4_+_68424444 1.621 NM_012108
STAP1
signal transducing adaptor family member 1
chrX_+_80457559 1.621 SH3BGRL
SH3 domain binding glutamic acid-rich protein like
chr12_-_102874321 1.613 IGF1
insulin-like growth factor 1 (somatomedin C)
chr5_+_49962920 1.604 PARP8
poly (ADP-ribose) polymerase family, member 8
chr4_-_176734181 1.604 NM_201591
GPM6A
glycoprotein M6A
chr14_-_106518424 1.593 IGH@
IGHA1
IGHG1
IGHG2
IGHM
immunoglobulin heavy locus
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 2 (G2m marker)
immunoglobulin heavy constant mu
chr18_-_52988916 1.589 NM_001243234
NM_001243235
TCF4

transcription factor 4

chr7_+_74188308 1.567 NM_000265
NCF1
NCF1B
neutrophil cytosolic factor 1
neutrophil cytosolic factor 1B pseudogene
chr1_-_111743297 1.558 DENND2D
DENN/MADD domain containing 2D
chr8_+_56792399 1.535 LYN
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr5_+_49961732 1.497 NM_001178055
PARP8
poly (ADP-ribose) polymerase family, member 8
chr6_+_32407618 1.496 NM_019111
HLA-DRA
major histocompatibility complex, class II, DR alpha
chr1_-_111743261 1.489 NM_024901
DENND2D
DENN/MADD domain containing 2D
chr12_+_14518608 1.483 NM_018179
ATF7IP
activating transcription factor 7 interacting protein
chr3_+_178254223 1.479 NM_181361
KCNMB2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr8_+_56792345 1.471 NM_001111097
NM_002350
LYN

v-yes-1 Yamaguchi sarcoma viral related oncogene homolog

chrX_-_70331297 1.463 NM_000206
IL2RG
interleukin 2 receptor, gamma
chr2_+_33661392 1.438 NM_170672
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr8_+_56792392 1.433 LYN
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr3_-_58200397 1.431 NM_004944
DNASE1L3
deoxyribonuclease I-like 3
chr6_-_32784727 1.423 NM_002120
HLA-DOB
major histocompatibility complex, class II, DO beta
chr6_-_143266283 1.389 NM_006734
HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
chr14_-_107078578 1.386


chr14_-_106552313 1.379 IGHA1
IGHD
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
chrX_-_135863104 1.379 ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr3_-_124842442 1.369 SLC12A8
solute carrier family 12 (potassium/chloride transporters), member 8
chrX_-_135863033 1.361 ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr12_-_102874373 1.360 NM_000618
NM_001111283
NM_001111285
IGF1


insulin-like growth factor 1 (somatomedin C)


chr19_-_17516383 1.336 NM_004335
BST2
bone marrow stromal cell antigen 2
chr1_-_31230594 1.319 LAPTM5
lysosomal protein transmembrane 5
chr11_+_128563772 1.316 NM_001167681
NM_002017
FLI1

Friend leukemia virus integration 1

chr14_-_106539099 1.304 IGHA1
IGHG1
IGHG3
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
chr3_-_57234279 1.289 NM_003865
HESX1
HESX homeobox 1
chr6_-_137540544 1.287 IFNGR1
interferon gamma receptor 1
chr1_+_209941894 1.286 TRAF3IP3
TRAF3 interacting protein 3
chr6_-_133078894 1.285 NM_001242350
NM_004665
VNN2

vanin 2

chr12_-_102874299 1.285 IGF1
insulin-like growth factor 1 (somatomedin C)
chr19_+_35820069 1.283 NM_001185099
NM_001185100
NM_001185101
NM_001771
CD22



CD22 molecule



chr6_-_137540551 1.277 NM_000416
IFNGR1
interferon gamma receptor 1
chrX_+_80457302 1.276 NM_003022
SH3BGRL
SH3 domain binding glutamic acid-rich protein like
chr18_-_53255361 1.261 TCF4
transcription factor 4
chr22_+_22764094 1.254


chr1_+_6052357 1.219 NM_001199861
KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chrX_-_80457440 1.218 NM_030763
HMGN5
high mobility group nucleosome binding domain 5
chr14_-_107122358 1.212


chr13_-_47012324 1.208 KIAA0226L
KIAA0226-like
chr17_-_41739261 1.204 NM_001040002
MEOX1
mesenchyme homeobox 1
chr21_+_27012045 1.204 JAM2
junctional adhesion molecule 2
chr5_-_88199868 1.179 NM_001131005
NM_001193347
MEF2C

myocyte enhancer factor 2C

chr2_-_191872322 1.175 STAT1
signal transducer and activator of transcription 1, 91kDa
chr14_+_105953531 1.162 CRIP1
cysteine-rich protein 1 (intestinal)
chr21_+_27012067 1.154 JAM2
junctional adhesion molecule 2
chr13_-_99910548 1.154 NM_001098200
NM_005292
GPR18

G protein-coupled receptor 18

chr11_+_102188180 1.153 NM_001165
NM_182962
BIRC3

baculoviral IAP repeat containing 3

chr16_+_30483959 1.152 NM_001114380
NM_002209
ITGAL

integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)

chr1_+_156119734 1.144 NM_001193301
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr14_-_23285011 1.141 NM_001126105
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr6_-_29527701 1.140 NM_006398
UBD
ubiquitin D
chr11_+_128563973 1.139 FLI1
Friend leukemia virus integration 1
chr7_+_116660263 1.131 ST7
suppression of tumorigenicity 7
chr3_+_134514044 1.125 NM_004441
EPHB1
EPH receptor B1
chr5_-_111092918 1.122 NM_004772
C5orf13
chromosome 5 open reading frame 13
chr5_-_111092865 1.116 C5orf13
chromosome 5 open reading frame 13
chr2_+_237478379 1.113 NM_020311
CXCR7
chemokine (C-X-C motif) receptor 7
chr7_-_37488894 1.110 NM_001206480
ELMO1
engulfment and cell motility 1
chr4_-_176733901 1.107 GPM6A
glycoprotein M6A
chrX_-_48776282 1.095 NM_006875
PIM2
pim-2 oncogene
chr12_+_27397077 1.093 NM_015000
STK38L
serine/threonine kinase 38 like
chr22_+_22385340 1.090


chrM_+_1670 1.081


chr22_+_23063107 1.079 IGLJ3
immunoglobulin lambda joining 3
chr3_+_88188261 1.074 NM_018293
ZNF654
zinc finger protein 654
chr14_-_89883306 1.069 NM_005197
FOXN3
forkhead box N3
chr14_-_107218786 1.067 IGHA1
IGHG1
IGHM
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chr1_+_64088886 1.065 NM_001172818
PGM1
phosphoglucomutase 1
chr2_-_89513056 1.056 IGKC
immunoglobulin kappa constant
chrX_-_135863502 1.041 NM_004840
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr1_-_42965948 1.038 TMSB4XP1
thymosin beta 4, X-linked pseudogene 1
chr5_-_169724817 1.038 NM_005565
LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr3_-_79817058 1.033 NM_002941
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr1_+_212782103 1.033 ATF3
activating transcription factor 3
chr12_-_102874158 1.026 IGF1
insulin-like growth factor 1 (somatomedin C)
chr1_-_23886284 1.022 NM_002167
ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr4_-_153303663 1.013 NM_001013415
FBXW7
F-box and WD repeat domain containing 7
chr22_+_22735202 1.012


chr14_-_106877689 1.010 IGHV4-31
IGH@
IGHA1
IGHA2
IGHG1
IGHG4
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy locus
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 4 (G4m marker)
immunoglobulin heavy constant mu
chr5_-_111312522 1.010 NM_001142474
NM_001142475
C5orf13

chromosome 5 open reading frame 13

chr22_+_23154240 1.009


chr3_-_124930192 1.008 NM_001195483
SLC12A8
solute carrier family 12 (potassium/chloride transporters), member 8
chr3_-_16554992 1.006 RFTN1
raftlin, lipid raft linker 1
chr18_-_53255734 1.005 NM_001083962
NM_001243230
NM_003199
TCF4


transcription factor 4


chr22_-_24096551 1.003 NM_013378
VPREB3
pre-B lymphocyte 3
chr14_-_107099379 1.003 IGHG1
IGHG3
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
chr2_+_86668488 1.000 NM_001146688
KDM3A
lysine (K)-specific demethylase 3A
chr1_+_198608244 1.000 PTPRC
protein tyrosine phosphatase, receptor type, C
chr13_-_41593405 0.997 ELF1
E74-like factor 1 (ets domain transcription factor)
chr6_-_11232901 0.997 NM_006403
NM_182966
NEDD9

neural precursor cell expressed, developmentally down-regulated 9

chrX_+_80457597 0.991 SH3BGRL
SH3 domain binding glutamic acid-rich protein like
chr3_+_130569368 0.984 NM_001199180
NM_001199181
NM_001199182
ATP2C1


ATPase, Ca++ transporting, type 2C, member 1


chr10_+_91061705 0.984 NM_001547
IFIT2
interferon-induced protein with tetratricopeptide repeats 2
chr5_-_169724782 0.980 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr1_+_101185195 0.977 NM_001078
NM_001199834
NM_080682
VCAM1


vascular cell adhesion molecule 1


chr1_+_198608136 0.974 NM_002838
NM_080921
NM_080923
PTPRC


protein tyrosine phosphatase, receptor type, C


chr12_-_102874340 0.972 IGF1
insulin-like growth factor 1 (somatomedin C)
chr14_-_106478129 0.968 IGHV4-31
IGHD
IGHG3
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
chr12_-_772525 0.964 NM_016533
NINJ2
ninjurin 2
chr12_+_113344811 0.950 OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr18_-_53257033 0.950 NM_001243227
NM_001243228
TCF4

transcription factor 4

chr14_-_106791054 0.949 IGHV4-31
IGHV3-30
IGHA1
IGHD
IGHG1
IGHG2
IGHG3
IGHM
SCFV
immunoglobulin heavy variable 4-31
immunoglobulin heavy variable 3-30
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 2 (G2m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
single-chain Fv fragment

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
6.30 2.73e-15 GO:0006955 immune response
4.52 1.90e-13 GO:0002376 immune system process
39.53 6.09e-05 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
1.69 7.62e-05 GO:0050896 response to stimulus
13.15 7.74e-05 GO:0034341 response to interferon-gamma
14.52 2.46e-04 GO:0060333 interferon-gamma-mediated signaling pathway
11.25 2.63e-04 GO:0050851 antigen receptor-mediated signaling pathway
6.83 2.81e-04 GO:0002253 activation of immune response
7.72 3.13e-04 GO:0002757 immune response-activating signal transduction
7.58 3.70e-04 GO:0002764 immune response-regulating signaling pathway
6.60 3.94e-04 GO:0045321 leukocyte activation
13.22 4.73e-04 GO:0071346 cellular response to interferon-gamma
10.33 5.07e-04 GO:0002429 immune response-activating cell surface receptor signaling pathway
5.21 5.34e-04 GO:0045087 innate immune response
10.03 6.39e-04 GO:0002768 immune response-regulating cell surface receptor signaling pathway
4.57 9.37e-04 GO:0050776 regulation of immune response
3.46 1.52e-03 GO:0006952 defense response
14.60 1.67e-03 GO:0019882 antigen processing and presentation
2.45 1.77e-03 GO:0007166 cell surface receptor linked signaling pathway
4.21 2.50e-03 GO:0001775 cell activation
2.40 2.61e-03 GO:0048583 regulation of response to stimulus
5.40 2.80e-03 GO:0050778 positive regulation of immune response
11.69 6.25e-03 GO:0042113 B cell activation
47.44 1.46e-02 GO:0045576 mast cell activation
3.97 2.26e-02 GO:0002684 positive regulation of immune system process
3.24 2.52e-02 GO:0002682 regulation of immune system process
6.03 2.75e-02 GO:0050867 positive regulation of cell activation
3.05 2.76e-02 GO:0048584 positive regulation of response to stimulus
6.87 3.68e-02 GO:0002252 immune effector process

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
45.18 4.66e-06 GO:0042613 MHC class II protein complex
21.09 3.01e-04 GO:0042611 MHC protein complex
1.75 4.03e-03 GO:0071944 cell periphery
1.73 6.79e-03 GO:0005886 plasma membrane
8.35 7.09e-03 GO:0005765 lysosomal membrane
1.98 1.53e-02 GO:0044459 plasma membrane part
6.28 3.39e-02 GO:0005774 vacuolar membrane
6.03 4.22e-02 GO:0044437 vacuolar part
10.77 4.59e-02 GO:0031902 late endosome membrane

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
34.79 7.82e-13 GO:0003823 antigen binding
22.33 3.49e-02 GO:0045028 purinergic nucleotide receptor activity, G-protein coupled