Motif ID: PRRX1,2.p2

Z-value: 1.537


Transcription factors associated with PRRX1,2.p2:

Gene SymbolEntrez IDGene Name
PRRX1 5396 paired related homeobox 1
PRRX2 51450 paired related homeobox 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
PRRX1chr1_+_1706333120.476.7e-02Click!
PRRX2chr9_+_1324280160.332.1e-01Click!


Activity profile for motif PRRX1,2.p2.

activity profile for motif PRRX1,2.p2


Sorted Z-values histogram for motif PRRX1,2.p2

Sorted Z-values for motif PRRX1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PRRX1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_-_38172862 8.526 NM_001135934
NM_001135935
NM_001135936
NM_006475
 POSTN



periostin, osteoblast specific factor



chr12_-_91505215 5.726 LUM
lumican
chr3_+_158787040 5.133 NM_001197113
NM_001197114
NM_001042705
NM_001042706
NM_001197100
 IQCJ-SCHIP1

IQCJ


IQCJ-SCHIP1 readthrough

IQ motif containing J


chr3_-_55515361 4.571 WNT5A
wingless-type MMTV integration site family, member 5A
chr11_+_5710816 4.561 NM_001199573
NM_006074
 TRIM22

tripartite motif containing 22

chr1_+_151032866 4.536 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr1_+_151032880 4.535 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr3_+_159557649 4.513 NM_001197109
 SCHIP1
schwannomin interacting protein 1
chr2_+_189839132 4.488 COL3A1
collagen, type III, alpha 1
chr1_+_151032683 4.419 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr3_+_159557745 4.417 SCHIP1
schwannomin interacting protein 1
chr12_-_91505541 4.355 NM_002345
 LUM
lumican
chr18_-_21891469 4.050 NM_001242508
 OSBPL1A
oxysterol binding protein-like 1A
chrX_+_135230736 3.954 NM_001159700
 FHL1
four and a half LIM domains 1
chr9_-_14086901 3.919 NFIB
nuclear factor I/B
chr11_+_5710926 3.826 TRIM22
tripartite motif containing 22
chr20_+_9288446 3.742 NM_000933
 PLCB4
phospholipase C, beta 4
chr8_-_49833823 3.632 NM_003068
 SNAI2
snail homolog 2 (Drosophila)
chr2_-_190927321 3.617 NM_005259
 MSTN
myostatin
chr1_-_103496768 3.548 COL11A1
collagen, type XI, alpha 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 16 of 16 entries
Enrichment   P-value GO Accession GO Term
9.20 2.01e-03 GO:0030198 extracellular matrix organization
8.99 4.39e-02 GO:0048706 embryonic skeletal system development
7.89 8.14e-06 GO:0007517 muscle organ development
7.49 7.21e-04 GO:0043062 extracellular structure organization
6.54 2.53e-02 GO:0043627 response to estrogen stimulus
5.89 6.39e-03 GO:0003012 muscle system process
5.78 2.14e-02 GO:0006936 muscle contraction
5.57 4.92e-04 GO:0061061 muscle structure development
4.55 1.09e-02 GO:0001501 skeletal system development
2.99 2.50e-02 GO:0007155 cell adhesion
2.99 2.50e-02 GO:0022610 biological adhesion
2.13 1.97e-02 GO:0048513 organ development
1.87 1.88e-02 GO:0048731 system development
1.80 9.81e-03 GO:0007275 multicellular organismal development
1.76 4.60e-02 GO:0048856 anatomical structure development
1.56 3.75e-02 GO:0032501 multicellular organismal process

Gene overrepresentation in compartment category:

Showing 1 to 10 of 10 entries
Enrichment   P-value GO Accession GO Term
26.96 2.06e-02 GO:0005583 fibrillar collagen
21.97 3.59e-03 GO:0005859 muscle myosin complex
19.77 5.60e-03 GO:0016460 myosin II complex
11.99 4.27e-02 GO:0005581 collagen
9.08 8.08e-05 GO:0044420 extracellular matrix part
6.66 1.14e-02 GO:0030016 myofibril
6.24 1.71e-02 GO:0043292 contractile fiber
4.85 9.06e-04 GO:0005578 proteinaceous extracellular matrix
4.01 5.95e-03 GO:0031012 extracellular matrix
2.02 2.19e-02 GO:0005576 extracellular region

Nothing significant found in function category.