Motif ID: REST.p3

Z-value: 0.720


Transcription factors associated with REST.p3:

Gene SymbolEntrez IDGene Name
REST 5978 RE1-silencing transcription factor

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
RESTchr4_+_57774090-0.476.9e-02Click!


Activity profile for motif REST.p3.

activity profile for motif REST.p3


Sorted Z-values histogram for motif REST.p3

Sorted Z-values for motif REST.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of REST.p3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_153141398 1.997 NM_000425
NM_001143963
NM_024003
L1CAM


L1 cell adhesion molecule


chr3_+_62305395 1.987 NM_020685
C3orf14
chromosome 3 open reading frame 14
chr3_+_62304667 1.796 C3orf14
chromosome 3 open reading frame 14
chr20_+_62328068 1.661 TNFRSF6B
tumor necrosis factor receptor superfamily, member 6b, decoy
chr20_+_62328002 1.562 NM_003823
TNFRSF6B
tumor necrosis factor receptor superfamily, member 6b, decoy
chr10_+_102790984 1.152 NM_030971
SFXN3
sideroflexin 3
chr2_+_46524448 0.891 NM_001430
EPAS1
endothelial PAS domain protein 1
chr3_+_193853937 0.877 HES1
hairy and enhancer of split 1, (Drosophila)
chr3_+_193853930 0.820 NM_005524
HES1
hairy and enhancer of split 1, (Drosophila)
chr1_-_209825797 0.799 NM_000228
LAMB3
laminin, beta 3
chr19_-_45927175 0.798 NM_001166049
NM_001983
ERCC1

excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)

chr19_-_45927142 0.730 ERCC1
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr19_-_45927081 0.695 ERCC1
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr19_-_45926819 0.689 NM_202001
ERCC1
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr19_-_45926759 0.630 ERCC1
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr7_+_145813452 0.537 NM_014141
CNTNAP2
contactin associated protein-like 2
chrX_-_47479229 0.466 NM_006950
NM_133499
SYN1

synapsin I

chr19_+_34175433 0.387 NM_022467
CHST8
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
chr12_+_175872 0.351 NM_001170738
IQSEC3
IQ motif and Sec7 domain 3
chr16_+_24267474 0.322 CACNG3
calcium channel, voltage-dependent, gamma subunit 3
chr17_-_3301703 0.281 NM_003553
OR1E1
olfactory receptor, family 1, subfamily E, member 1
chr17_-_3337134 0.252 NM_003554
OR1E2
olfactory receptor, family 1, subfamily E, member 2
chr16_+_24267672 0.224 CACNG3
calcium channel, voltage-dependent, gamma subunit 3
chr15_+_94774763 0.211 MCTP2
multiple C2 domains, transmembrane 2
chr5_+_33936490 0.207 NM_016568
RXFP3
relaxin/insulin-like family peptide receptor 3
chr8_-_145559831 0.205 NM_031309
SCRT1
scratch homolog 1, zinc finger protein (Drosophila)
chr16_+_3019341 0.191 NM_152341
PAQR4
progestin and adipoQ receptor family member IV
chr10_-_102790850 0.155 PDZD7
PDZ domain containing 7
chr4_-_175750377 0.153 NM_001042543
NM_006529
GLRA3

glycine receptor, alpha 3

chr14_+_93389491 0.152 CHGA
chromogranin A (parathyroid secretory protein 1)
chr11_+_62380212 0.152 NM_000327
ROM1
retinal outer segment membrane protein 1
chr10_-_102790877 0.144 NM_001195263
NM_024895
PDZD7

PDZ domain containing 7

chr12_+_113229548 0.139 NM_001143854
NM_014954
RPH3A

rabphilin 3A homolog (mouse)

chrX_+_153237990 0.138 NM_003492
TMEM187
transmembrane protein 187
chr9_+_140033588 0.135 NM_000832
NM_001185090
NM_001185091
NM_007327
NM_021569
GRIN1




glutamate receptor, ionotropic, N-methyl D-aspartate 1




chr20_+_44657858 0.135 SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr6_+_138725314 0.133 NM_014320
HEBP2
heme binding protein 2
chr6_+_154360442 0.132 NM_000914
NM_001008503
NM_001008504
NM_001008505
NM_001145282
NM_001145283
NM_001145284
NM_001145285
NM_001145286
OPRM1








opioid receptor, mu 1








chr6_+_138725458 0.131 HEBP2
heme binding protein 2
chr15_-_27018917 0.128 NM_021912
GABRB3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr11_-_123524881 0.122 SCN3B
sodium channel, voltage-gated, type III, beta
chr2_-_51259536 0.112 NM_001135659
NM_004801
NRXN1

neurexin 1

chr14_+_93389444 0.103 NM_001275
CHGA
chromogranin A (parathyroid secretory protein 1)
chr20_+_13765645 0.101 NM_001039375
NM_024120
C20orf7

chromosome 20 open reading frame 7

chrX_-_49056638 0.095 NM_003179
SYP
synaptophysin
chr3_-_113897849 0.095 NM_000796
NM_033663
DRD3

dopamine receptor D3

chr3_-_48700317 0.086 NM_001407
CELSR3
cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)
chr6_+_43149905 0.082 NM_015089
CUL9
cullin 9
chr20_+_44657812 0.070 NM_020708
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr4_+_158141735 0.064 NM_000826
NM_001083619
NM_001083620
GRIA2


glutamate receptor, ionotropic, AMPA 2


chr11_-_128807712 0.055 NM_001195194
TP53AIP1
tumor protein p53 regulated apoptosis inducing protein 1
chr10_+_26505593 0.047 GAD2
glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
chr18_+_57567191 0.047 NM_021127
PMAIP1
phorbol-12-myristate-13-acetate-induced protein 1
chr9_-_74061819 0.047 TRPM3
transient receptor potential cation channel, subfamily M, member 3
chr15_+_69222838 0.044 NM_145658
NM_001184780
SPESP1
NOX5
sperm equatorial segment protein 1
NADPH oxidase, EF-hand calcium binding domain 5
chr14_+_21156922 0.039 NM_001097577
NM_194431
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr20_-_62284701 0.037 NM_015894
STMN3
stathmin-like 3
chr16_+_69345250 0.028 NM_013245
VPS4A
vacuolar protein sorting 4 homolog A (S. cerevisiae)
chr20_+_57428035 0.025 NM_001077490
NM_080425
GNAS

GNAS complex locus

chrX_-_153141284 0.024 L1CAM
L1 cell adhesion molecule
chr9_-_123812535 0.022 NM_001735
C5
complement component 5
chr17_-_65362667 0.021 NM_002816
NM_174871
PSMD12

proteasome (prosome, macropain) 26S subunit, non-ATPase, 12

chr20_+_33814538 0.019 NM_006690
MMP24
matrix metallopeptidase 24 (membrane-inserted)
chr9_-_139096954 0.016 NM_178138
LHX3
LIM homeobox 3
chr1_-_20834609 0.016 NM_024544
MUL1
mitochondrial E3 ubiquitin protein ligase 1
chr1_-_175712669 0.016 NM_003285
TNR
tenascin R (restrictin, janusin)
chr20_+_5891973 0.014 NM_001819
CHGB
chromogranin B (secretogranin 1)
chr21_-_35828038 0.013 NM_001127670
KCNE1
potassium voltage-gated channel, Isk-related family, member 1
chr6_+_153071931 0.012 NM_003381
NM_194435
VIP

vasoactive intestinal peptide

chr11_+_32112607 0.011 RCN1
reticulocalbin 1, EF-hand calcium binding domain
chr11_+_22359666 0.011 NM_020346
SLC17A6
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
chr11_-_6676851 0.010 NM_003737
DCHS1
dachsous 1 (Drosophila)
chr3_+_52812438 0.007 NM_001166434
ITIH1
inter-alpha-trypsin inhibitor heavy chain 1
chr1_-_13184325 0.006 NM_001136561
LOC440563
heterogeneous nuclear ribonucleoprotein C-like
chr1_-_20834516 0.005 MUL1
mitochondrial E3 ubiquitin protein ligase 1
chr5_+_175298604 0.005 CPLX2
complexin 2

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.