Motif ID: RREB1.p2

Z-value: 1.838


Transcription factors associated with RREB1.p2:

Gene SymbolEntrez IDGene Name
RREB1 6239 ras responsive element binding protein 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
RREB1chr6_+_71077990.533.7e-02Click!


Activity profile for motif RREB1.p2.

activity profile for motif RREB1.p2


Sorted Z-values histogram for motif RREB1.p2

Sorted Z-values for motif RREB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RREB1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_151938194 4.455 NM_005362
MAGEA3
melanoma antigen family A, 3
chrX_+_151867244 4.404 NM_005363
NM_175868
MAGEA2
MAGEA6

melanoma antigen family A, 2
melanoma antigen family A, 6

chrX_-_151903100 4.065 NM_001166386
NM_001166387
NM_005367
MAGEA12


melanoma antigen family A, 12


chrX_+_151903218 3.091 NM_001102576
NM_153478
CSAG1

chondrosarcoma associated gene 1

chrX_-_152486073 3.074 NM_004988
MAGEA1
melanoma antigen family A, 1 (directs expression of antigen MZ2-E)
chrX_+_151883074 2.687 NM_005361
NM_175742
NM_175743
MAGEA2


melanoma antigen family A, 2


chr19_-_55658310 2.452 TNNT1
troponin T type 1 (skeletal, slow)
chr6_+_3000026 2.316 NM_000904
NQO2
NAD(P)H dehydrogenase, quinone 2
chr11_+_46403279 2.315 MDK
midkine (neurite growth-promoting factor 2)
chrX_-_151922329 2.272 NM_005361
NM_175742
NM_175743
MAGEA2


melanoma antigen family A, 2


chr11_+_46403260 2.181 MDK
midkine (neurite growth-promoting factor 2)
chr11_+_46403205 2.121 NM_002391
MDK
midkine (neurite growth-promoting factor 2)
chr20_-_22564893 2.120 FOXA2
forkhead box A2
chrX_-_137793826 2.067 NM_004114
FGF13
fibroblast growth factor 13
chrX_-_137793394 1.791 FGF13
fibroblast growth factor 13
chr21_-_44495894 1.673 NM_000071
CBS
cystathionine-beta-synthase
chr11_+_46403302 1.670 NM_001012333
MDK
midkine (neurite growth-promoting factor 2)
chr19_+_860615 1.630 CFD
complement factor D (adipsin)
chr19_-_55660557 1.591 NM_001126132
NM_001126133
NM_003283
TNNT1


troponin T type 1 (skeletal, slow)


chr22_-_22901421 1.569 NM_206955
NM_206956
NM_006115
NM_206953
NM_206954
PRAME




preferentially expressed antigen in melanoma




chr19_-_18717577 1.485 CRLF1
cytokine receptor-like factor 1
chr19_-_18717631 1.466 NM_004750
CRLF1
cytokine receptor-like factor 1
chr20_-_22565050 1.373 NM_021784
FOXA2
forkhead box A2
chr19_-_18717467 1.346 CRLF1
cytokine receptor-like factor 1
chr1_-_161193190 1.310 APOA2
apolipoprotein A-II
chrX_-_39956655 1.293 NM_001123385
NM_017745
BCOR

BCL6 corepressor

chr2_-_218843541 1.242 TNS1
tensin 1
chr21_-_28339405 1.229 NM_007038
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chrX_-_151286410 1.224 NM_021049
MAGEA5
melanoma antigen family A, 5
chr3_-_185542807 1.173 NM_001007225
NM_006548
IGF2BP2

insulin-like growth factor 2 mRNA binding protein 2

chrX_+_152907892 1.125 NM_001395
DUSP9
dual specificity phosphatase 9
chr12_-_54694717 1.118 NM_001136023
NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr21_-_44496423 1.104 NM_001178008
NM_001178009
CBS

cystathionine-beta-synthase

chrX_-_148669108 1.079 NM_005365
NM_001080790
MAGEA9
MAGEA9B
melanoma antigen family A, 9
melanoma antigen family A, 9B
chr5_+_176513819 1.052 NM_002011
NM_213647
FGFR4

fibroblast growth factor receptor 4

chr7_-_150675236 1.051 NM_000238
NM_172056
KCNH2

potassium voltage-gated channel, subfamily H (eag-related), member 2

chrX_+_148863592 1.041 NM_005365
NM_001080790
MAGEA9
MAGEA9B
melanoma antigen family A, 9
melanoma antigen family A, 9B
chrX_-_153881757 1.038 NM_020994
NM_172377
CTAG2

cancer/testis antigen 2

chrX_+_152908819 1.030 DUSP9
dual specificity phosphatase 9
chr16_-_28608367 1.028 NM_001054
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr16_+_85645014 1.003 NM_001134473
KIAA0182
KIAA0182
chr10_+_5454516 0.997 NM_001047160
NET1
neuroepithelial cell transforming 1
chr12_-_54694647 0.996 NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr11_-_2158510 0.995 IGF2
insulin-like growth factor 2 (somatomedin A)
chr1_-_1293907 0.990 NM_032348
MXRA8
matrix-remodelling associated 8
chr6_+_32121775 0.963 NM_001204103
NM_005155
PPT2-EGFL8
PPT2

PPT2-EGFL8 readthrough
palmitoyl-protein thioesterase 2

chr16_-_28621279 0.933 NM_001055
NM_177529
SULT1A1

sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1

chr2_-_220436267 0.931 NM_001173408
NM_001173431
NM_015311
OBSL1


obscurin-like 1


chr12_+_57849086 0.931 NM_031479
INHBE
inhibin, beta E
chr16_+_30210548 0.926 NM_001017390
NM_177552
SULT1A4
SULT1A3
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr2_+_8822112 0.910 NM_002166
ID2
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
chr10_+_114709963 0.905 NM_001146274
NM_001146283
NM_001146284
NM_001146285
NM_001146286
NM_001198525
NM_001198526
NM_001198527
NM_001198528
NM_001198529
NM_001198530
NM_001198531
NM_030756
TCF7L2












transcription factor 7-like 2 (T-cell specific, HMG-box)












chr19_-_18548971 0.889 NM_001170938
NM_016368
ISYNA1

inositol-3-phosphate synthase 1

chr19_-_18548788 0.887 NM_001170939
ISYNA1
inositol-3-phosphate synthase 1
chr7_+_94023872 0.881 NM_000089
COL1A2
collagen, type I, alpha 2
chr18_+_33767420 0.877 NM_017947
MOCOS
molybdenum cofactor sulfurase
chr20_+_31350387 0.851 DNMT3B
DNA (cytosine-5-)-methyltransferase 3 beta
chr2_-_200322699 0.849 NM_001172509
SATB2
SATB homeobox 2
chr2_-_128432642 0.843 NM_001136037
NM_001161403
LIMS2

LIM and senescent cell antigen-like domains 2

chr3_-_185542744 0.837 IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chrX_-_11284094 0.829 NM_013423
ARHGAP6
Rho GTPase activating protein 6
chr1_-_21978287 0.818 NM_001145658
RAP1GAP
RAP1 GTPase activating protein
chr7_-_143599163 0.816 NM_014719
NM_001206938
FAM115A

family with sequence similarity 115, member A

chr20_+_34742656 0.813 NM_012156
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chrX_+_153813417 0.813 NM_001327
NM_139250
CTAG1B
CTAG1A
cancer/testis antigen 1B
cancer/testis antigen 1A
chr17_-_46703613 0.800 NM_024017
HOXB9
homeobox B9
chr21_+_47649066 0.799 MCM3AP-AS1
MCM3AP antisense RNA 1 (non-protein coding)
chr10_-_95360959 0.792 NM_006744
RBP4
retinol binding protein 4, plasma
chr17_+_79989485 0.787 NM_005052
RAC3
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr1_+_21835915 0.780 ALPL
alkaline phosphatase, liver/bone/kidney
chr5_-_134369841 0.779 NM_002653
PITX1
paired-like homeodomain 1
chr9_+_71320105 0.773 NM_003558
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr11_-_75062650 0.765 NM_004041
NM_020251
ARRB1

arrestin, beta 1

chr14_-_21994342 0.749 SALL2
sal-like 2 (Drosophila)
chr7_+_73868111 0.747 NM_001199207
NM_005685
NM_016328
GTF2IRD1


GTF2I repeat domain containing 1


chr7_+_73868236 0.743 GTF2IRD1
GTF2I repeat domain containing 1
chr7_-_92465876 0.741 CDK6
cyclin-dependent kinase 6
chr7_-_100239136 0.738 NM_003227
TFR2
transferrin receptor 2
chr5_-_172756505 0.710 NM_003714
STC2
stanniocalcin 2
chr6_+_20404033 0.695 NM_001243076
E2F3
E2F transcription factor 3
chr6_-_6320897 0.687 NM_000129
F13A1
coagulation factor XIII, A1 polypeptide
chr16_+_29471206 0.684 NM_001017390
NM_177552
SULT1A4
SULT1A3
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr2_+_46926049 0.683 NM_014011
SOCS5
suppressor of cytokine signaling 5
chr1_-_150947456 0.677 NM_022075
NM_181746
CERS2

ceramide synthase 2

chr17_-_76124791 0.676 NM_001127198
TMC6
transmembrane channel-like 6
chr6_-_46459010 0.674 NM_001251974
RCAN2
regulator of calcineurin 2
chr19_+_925984 0.674 NM_005224
ARID3A
AT rich interactive domain 3A (BRIGHT-like)
chrY_+_15016775 0.674 DDX3Y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr10_-_75415748 0.668 NM_001114133
SYNPO2L
synaptopodin 2-like
chr7_+_73868397 0.667 GTF2IRD1
GTF2I repeat domain containing 1
chrY_+_15016698 0.665 NM_004660
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr15_+_85291802 0.660 NM_014630
ZNF592
zinc finger protein 592
chr20_-_1165116 0.656 NM_018354
TMEM74B
transmembrane protein 74B
chr19_+_708766 0.653 NM_001040134
NM_002579
PALM

paralemmin

chr3_-_13008959 0.653 NM_014869
IQSEC1
IQ motif and Sec7 domain 1
chr3_+_52009036 0.653 NM_015407
ABHD14A-ACY1
ABHD14A
ABHD14A-ACY1 readthrough (non-protein coding)
abhydrolase domain containing 14A
chrX_+_30233674 0.652 NM_002364
MAGEB2
melanoma antigen family B, 2
chr20_-_47804675 0.649 STAU1
staufen, RNA binding protein, homolog 1 (Drosophila)
chr14_-_21493858 0.645 NDRG2
NDRG family member 2
chr2_-_227664330 0.644 IRS1
insulin receptor substrate 1
chr6_-_6320875 0.641 F13A1
coagulation factor XIII, A1 polypeptide
chr1_-_150947292 0.641 CERS2
ceramide synthase 2
chr14_-_65346554 0.634 SPTB
spectrin, beta, erythrocytic
chr3_+_12329332 0.626 NM_005037
NM_138712
PPARG

peroxisome proliferator-activated receptor gamma

chr11_-_414975 0.625 NM_001135054
SIGIRR
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr11_-_85780105 0.615 NM_001008660
NM_001206946
NM_007166
PICALM


phosphatidylinositol binding clathrin assembly protein


chr4_-_109089444 0.609 NM_001130713
NM_001130714
NM_016269
LEF1


lymphoid enhancer-binding factor 1


chr1_-_161193375 0.609 NM_001643
APOA2
apolipoprotein A-II
chr1_-_38471170 0.604 NM_001243878
NM_004468
FHL3

four and a half LIM domains 3

chr11_-_34379526 0.601 NM_145804
ABTB2
ankyrin repeat and BTB (POZ) domain containing 2
chr1_-_150947154 0.600 CERS2
ceramide synthase 2
chr10_-_735522 0.597 NM_014974
DIP2C
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr19_+_52800424 0.597 NM_144684
ZNF480
zinc finger protein 480
chrX_-_48693934 0.594 NM_013271
PCSK1N
proprotein convertase subtilisin/kexin type 1 inhibitor
chr14_-_21493910 0.586 NM_016250
NM_201535
NM_201536
NM_201537
NDRG2



NDRG family member 2



chr11_-_119293848 0.585 THY1
Thy-1 cell surface antigen
chr1_-_150947202 0.584 CERS2
ceramide synthase 2
chr12_-_71314247 0.583 PTPRR
protein tyrosine phosphatase, receptor type, R
chr7_-_148581379 0.583 EZH2
enhancer of zeste homolog 2 (Drosophila)
chr18_-_25757351 0.577 NM_001792
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr15_+_63335086 0.575 TPM1
tropomyosin 1 (alpha)
chr1_-_24104743 0.573 LOC100506963
uncharacterized LOC100506963
chr4_-_5890142 0.573 CRMP1
collapsin response mediator protein 1
chrX_-_151306959 0.570 NM_001204811
NM_001011543
NM_001251828
NM_021048
MAGEA10-MAGEA5
MAGEA10


MAGEA10-MAGEA5 readthrough
melanoma antigen family A, 10


chr8_+_21777165 0.567 NM_015024
XPO7
exportin 7
chr7_-_92465929 0.566 NM_001145306
CDK6
cyclin-dependent kinase 6
chr15_-_83240499 0.562 NM_001079533
NM_001079534
NM_001079535
CPEB1


cytoplasmic polyadenylation element binding protein 1


chr19_+_14544216 0.560 PKN1
protein kinase N1
chr1_-_32801606 0.558 NM_023009
MARCKSL1
MARCKS-like 1
chr20_+_31350190 0.558 NM_001207055
NM_001207056
NM_006892
NM_175848
NM_175849
DNMT3B




DNA (cytosine-5-)-methyltransferase 3 beta




chr1_+_15250578 0.555 NM_001018000
KAZN
kazrin, periplakin interacting protein
chr12_-_56101465 0.553 ITGA7
integrin, alpha 7
chr8_+_142432006 0.550 NM_007079
NM_032611
PTP4A3

protein tyrosine phosphatase type IVA, member 3

chr14_-_103989195 0.550 NM_001823
CKB
creatine kinase, brain
chr8_+_21777216 0.546 XPO7
exportin 7
chr10_-_76868853 0.545 NM_001007271
NM_001007272
NM_001007273
DUSP13


dual specificity phosphatase 13


chr20_-_62601140 0.545 NM_020713
ZNF512B
zinc finger protein 512B
chr6_+_160390128 0.544 NM_000876
IGF2R
insulin-like growth factor 2 receptor
chr16_+_202853 0.542 NM_005332
HBZ
hemoglobin, zeta
chr20_+_61427804 0.542 NM_018270
C20orf20
chromosome 20 open reading frame 20
chr7_-_752083 0.540 PRKAR1B
protein kinase, cAMP-dependent, regulatory, type I, beta
chr1_+_39456887 0.540 NM_001136275
NM_024595
AKIRIN1

akirin 1

chr11_-_27494232 0.539 NM_018490
LGR4
leucine-rich repeat containing G protein-coupled receptor 4
chr5_+_92920592 0.538 NR2F1
NR2F2
nuclear receptor subfamily 2, group F, member 1
nuclear receptor subfamily 2, group F, member 2
chr1_+_21835841 0.536 NM_000478
NM_001127501
NM_001177520
ALPL


alkaline phosphatase, liver/bone/kidney


chr19_+_45449228 0.534 NM_000483
APOC2
apolipoprotein C-II
chrX_-_153847390 0.531 NM_001327
NM_139250
CTAG1B
CTAG1A
cancer/testis antigen 1B
cancer/testis antigen 1A
chr5_-_77590466 0.527 AP3B1
adaptor-related protein complex 3, beta 1 subunit
chr17_-_74707066 0.527 MXRA7
matrix-remodelling associated 7
chr21_+_44073650 0.523 NM_001001567
NM_001001568
NM_001001569
NM_001001570
NM_001001571
NM_001001572
NM_001001573
NM_001001574
NM_001001575
NM_001001576
NM_001001577
NM_001001578
NM_001001579
NM_001001580
NM_001001581
NM_001001582
NM_001001583
NM_001001584
NM_001001585
NM_002606
PDE9A



















phosphodiesterase 9A



















chr14_-_21493122 0.523 NM_201538
NM_201539
NM_201540
NM_201541
NDRG2



NDRG family member 2



chr1_-_150947305 0.523 CERS2
ceramide synthase 2
chr18_-_25756946 0.523 CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr6_-_2971981 0.522 SERPINB6
serpin peptidase inhibitor, clade B (ovalbumin), member 6
chr17_-_74707000 0.518 NM_001008528
NM_001008529
NM_198530
MXRA7


matrix-remodelling associated 7


chr19_-_6720585 0.514 NM_000064
C3
complement component 3
chr10_+_22610138 0.514 NM_005180
BMI1
BMI1 polycomb ring finger oncogene
chr2_-_158731622 0.513 NM_001105
ACVR1
activin A receptor, type I
chr12_-_6716475 0.512 CHD4
chromodomain helicase DNA binding protein 4
chr18_+_12948010 0.498 SEH1L
SEH1-like (S. cerevisiae)
chr4_-_100009851 0.493 ADH5
alcohol dehydrogenase 5 (class III), chi polypeptide
chr11_+_46402333 0.490 NM_001012334
MDK
midkine (neurite growth-promoting factor 2)
chr20_-_47804903 0.490 NM_001037328
NM_004602
NM_017452
NM_017453
NM_017454
STAU1




staufen, RNA binding protein, homolog 1 (Drosophila)




chr19_+_45349584 0.489 PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr4_-_100009912 0.489 NM_000671
ADH5
alcohol dehydrogenase 5 (class III), chi polypeptide
chr1_+_11333244 0.483 NM_013319
UBIAD1
UbiA prenyltransferase domain containing 1
chr14_+_29236171 0.481 NM_005249
FOXG1
forkhead box G1
chr19_-_49944613 0.481 NM_020309
SLC17A7
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
chr3_+_8775485 0.478 NM_001234
NM_033337
CAV3

caveolin 3

chr12_-_6716550 0.476 NM_001273
CHD4
chromodomain helicase DNA binding protein 4
chr6_-_2971787 0.474 SERPINB6
serpin peptidase inhibitor, clade B (ovalbumin), member 6
chr14_-_103989112 0.474 CKB
creatine kinase, brain
chr8_-_145638929 0.468 SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr2_-_145277568 0.467 ZEB2
zinc finger E-box binding homeobox 2
chr19_-_46285645 0.467 DMPK
dystrophia myotonica-protein kinase
chr7_+_66093854 0.465 NM_001167961
NM_153033
KCTD7

potassium channel tetramerisation domain containing 7

chr4_+_123747815 0.464 NM_002006
FGF2
fibroblast growth factor 2 (basic)
chr16_+_2039945 0.464 NM_004209
SYNGR3
synaptogyrin 3
chr2_-_219134795 0.461 AAMP
angio-associated, migratory cell protein
chr3_-_50349811 0.460 NM_153281
HYAL1
hyaluronoglucosaminidase 1
chrX_+_9432980 0.460 NM_005647
TBL1X
transducin (beta)-like 1X-linked
chr22_+_45064323 0.459 NM_001017528
NM_001017529
PRR5

proline rich 5 (renal)

chr2_+_5832778 0.457 NM_003108
SOX11
SRY (sex determining region Y)-box 11
chr2_+_26467787 0.456 HADHB
hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
chr20_+_34680569 0.456 EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr2_-_158732341 0.453 NM_001111067
ACVR1
activin A receptor, type I
chr2_+_102508377 0.453 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr6_+_32121228 0.453 NM_138717
PPT2
palmitoyl-protein thioesterase 2
chr10_+_21823093 0.453 NM_001195627
NM_001195628
NM_001195630
NM_004641
MLLT10



myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10



chr2_-_219134865 0.449 NM_001087
AAMP
angio-associated, migratory cell protein
chr5_+_612404 0.446 NM_018140
CEP72
centrosomal protein 72kDa
chr10_+_21823573 0.445 NM_001195626
MLLT10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr16_-_30798206 0.445 NM_001080417
ZNF629
zinc finger protein 629
chr7_-_148581359 0.445 EZH2
enhancer of zeste homolog 2 (Drosophila)
chr11_-_8739398 0.444 ST5
suppression of tumorigenicity 5
chr15_-_35087748 0.442 NM_005159
ACTC1
actin, alpha, cardiac muscle 1
chr19_+_35629727 0.441 NM_021902
FXYD1
FXYD domain containing ion transport regulator 1
chr6_+_30312899 0.440 NM_001199120
NM_001199121
NM_024839
RPP21


ribonuclease P/MRP 21kDa subunit


chr2_-_145277879 0.438 NM_001171653
NM_014795
ZEB2

zinc finger E-box binding homeobox 2

chr2_-_148779172 0.437 NM_181742
ORC4
origin recognition complex, subunit 4

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.