Motif ID: RXRG_dimer.p3

Z-value: 1.213


Transcription factors associated with RXRG_dimer.p3:

Gene SymbolEntrez IDGene Name
NR1H2 7376 nuclear receptor subfamily 1, group H, member 2
PPARA 5465 peroxisome proliferator-activated receptor alpha
PPARG 5468 peroxisome proliferator-activated receptor gamma
RXRA 6256 retinoid X receptor, alpha
RXRB 6257 retinoid X receptor, beta
RXRG 6258 retinoid X receptor, gamma

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NR1H2chr19_+_50879681-0.674.9e-03Click!
RXRBchr6_-_331683690.552.7e-02Click!
PPARGchr3_+_12329332,
chr3_+_12392993,
chr3_+_12330336		0.439.9e-02Click!
RXRGchr1_-_165414499-0.421.1e-01Click!
RXRAchr9_+_1372183240.361.7e-01Click!
PPARAchr22_+_46546690-0.341.9e-01Click!


Activity profile for motif RXRG_dimer.p3.

activity profile for motif RXRG_dimer.p3


Sorted Z-values histogram for motif RXRG_dimer.p3

Sorted Z-values for motif RXRG_dimer.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of RXRG_dimer.p3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_116708334 3.908 NM_000039
 APOA1
apolipoprotein A-I
chr11_+_116700620 3.409 NM_000040
 APOC3
apolipoprotein C-III
chr6_+_31623688 2.867 APOM
apolipoprotein M
chr6_+_31623668 2.744 NM_019101
 APOM
apolipoprotein M
chr20_+_56136136 2.321 NM_002591
 PCK1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr10_-_52645384 2.093 A1CF
APOBEC1 complementation factor
chr2_+_219283809 2.075 NM_007127
 VIL1
villin 1
chr19_+_50016490 2.069 FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr19_+_50016500 2.015 FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr5_-_42811959 1.997 NM_001085486
NM_001093726
NM_005410
 SEPP1


selenoprotein P, plasma, 1


chr10_-_52645430 1.697 NM_001198818
NM_001198819
NM_001198820
NM_014576
NM_138932
NM_138933
 A1CF





APOBEC1 complementation factor





chr2_+_109065665 1.694 GCC2
GRIP and coiled-coil domain containing 2
chr12_-_6665220 1.579 NM_001039670
NM_001193457
NM_080730
 IFFO1


intermediate filament family orphan 1


chr1_-_173886464 1.519 NM_000488
 SERPINC1
serpin peptidase inhibitor, clade C (antithrombin), member 1
chr2_+_109065576 1.422 NM_181453
 GCC2
GRIP and coiled-coil domain containing 2
chr19_+_50016435 1.404 NM_004107
 FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr5_+_92918924 1.390 NM_005654
 NR2F1
nuclear receptor subfamily 2, group F, member 1
chr1_+_145727665 1.270 NM_001201325
NM_001201326
NM_002614
 PDZK1


PDZ domain containing 1


chr10_+_102732285 1.263 NM_001203244
NM_017893
 SEMA4G

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G

chr2_+_178257488 1.218 AGPS
alkylglycerone phosphate synthase

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 24 entries
Enrichment   P-value GO Accession GO Term
366.65 1.72e-03 GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling
275.00 3.44e-03 GO:0010901 regulation of very-low-density lipoprotein particle remodeling
275.00 3.44e-03 GO:0032488 Cdc42 protein signal transduction
220.01 5.73e-03 GO:0034380 high-density lipoprotein particle assembly
183.35 8.59e-03 GO:0034384 high-density lipoprotein particle clearance
137.52 2.00e-04 GO:0034377 plasma lipoprotein particle assembly
137.52 2.00e-04 GO:0065005 protein-lipid complex assembly
122.25 2.05e-02 GO:0033700 phospholipid efflux
117.88 3.29e-04 GO:0034375 high-density lipoprotein particle remodeling
97.09 6.13e-04 GO:0043691 reverse cholesterol transport
86.87 8.72e-04 GO:0034381 plasma lipoprotein particle clearance
82.53 1.02e-03 GO:0033344 cholesterol efflux
78.60 1.19e-03 GO:0034367 macromolecular complex remodeling
78.60 1.19e-03 GO:0034368 protein-lipid complex remodeling
78.60 1.19e-03 GO:0034369 plasma lipoprotein particle remodeling
66.03 2.06e-03 GO:0071825 protein-lipid complex subunit organization
66.03 2.06e-03 GO:0071827 plasma lipoprotein particle organization
48.57 5.29e-03 GO:0097006 regulation of plasma lipoprotein particle levels
43.46 7.43e-03 GO:0030301 cholesterol transport
42.34 8.04e-03 GO:0015918 sterol transport

Gene overrepresentation in compartment category:

Showing 1 to 6 of 6 entries
Enrichment   P-value GO Accession GO Term
206.26 1.22e-05 GO:0034366 spherical high-density lipoprotein particle
91.70 1.76e-04 GO:0034361 very-low-density lipoprotein particle
91.70 1.76e-04 GO:0034385 triglyceride-rich lipoprotein particle
75.03 3.31e-04 GO:0034364 high-density lipoprotein particle
51.60 1.05e-03 GO:0032994 protein-lipid complex
51.60 1.05e-03 GO:0034358 plasma lipoprotein particle

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
Enrichment   P-value GO Accession GO Term
366.65 3.78e-04 GO:0070653 high-density lipoprotein particle receptor binding