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Motif ID: RXRG_dimer.p3

Z-value: 1.213

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr11_-_116708334	3.908	NM_000039	APOA1	apolipoprotein A-I
chr11_+_116700620	3.409	NM_000040	APOC3	apolipoprotein C-III
chr6_+_31623688	2.867		APOM	apolipoprotein M
chr6_+_31623668	2.744	NM_019101	APOM	apolipoprotein M
chr20_+_56136136	2.321	NM_002591	PCK1	phosphoenolpyruvate carboxykinase 1 (soluble)
chr10_-_52645384	2.093		A1CF	APOBEC1 complementation factor
chr2_+_219283809	2.075	NM_007127	VIL1	villin 1
chr19_+_50016490	2.069		FCGRT	Fc fragment of IgG, receptor, transporter, alpha
chr19_+_50016500	2.015		FCGRT	Fc fragment of IgG, receptor, transporter, alpha
chr5_-_42811959	1.997	NM_001085486 NM_001093726 NM_005410	SEPP1	selenoprotein P, plasma, 1
chr10_-_52645430	1.697	NM_001198818 NM_001198819 NM_001198820 NM_014576 NM_138932 NM_138933	A1CF	APOBEC1 complementation factor
chr2_+_109065665	1.694		GCC2	GRIP and coiled-coil domain containing 2
chr12_-_6665220	1.579	NM_001039670 NM_001193457 NM_080730	IFFO1	intermediate filament family orphan 1
chr1_-_173886464	1.519	NM_000488	SERPINC1	serpin peptidase inhibitor, clade C (antithrombin), member 1
chr2_+_109065576	1.422	NM_181453	GCC2	GRIP and coiled-coil domain containing 2
chr19_+_50016435	1.404	NM_004107	FCGRT	Fc fragment of IgG, receptor, transporter, alpha
chr5_+_92918924	1.390	NM_005654	NR2F1	nuclear receptor subfamily 2, group F, member 1
chr1_+_145727665	1.270	NM_001201325 NM_001201326 NM_002614	PDZK1	PDZ domain containing 1
chr10_+_102732285	1.263	NM_001203244 NM_017893	SEMA4G	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr2_+_178257488	1.218		AGPS	alkylglycerone phosphate synthase
chr13_+_100741268	1.185	NM_000282 NM_001127692 NM_001178004	PCCA	propionyl CoA carboxylase, alpha polypeptide
chr1_+_145727712	1.169		PDZK1	PDZ domain containing 1
chr20_-_20033005	1.162		CRNKL1	crooked neck pre-mRNA splicing factor-like 1 (Drosophila)
chr7_-_65447233	1.148	NM_000181	GUSB	glucuronidase, beta
chr16_+_4714709	1.103		MGRN1	mahogunin, ring finger 1
chr2_+_178257371	1.074	NM_003659	AGPS	alkylglycerone phosphate synthase
chr2_+_138721807	1.074	NM_001024074 NM_001024075 NM_006895	HNMT	histamine N-methyltransferase
chr2_-_64246431	1.034		VPS54	vacuolar protein sorting 54 homolog (S. cerevisiae)
chr20_+_30945988	1.024	NM_001164603 NM_015338	ASXL1	additional sex combs like 1 (Drosophila)
chr7_-_65447162	0.988		GUSB	glucuronidase, beta
chr16_-_87970107	0.962	NM_001739	CA5A	carbonic anhydrase VA, mitochondrial
chr7_-_65447187	0.915		GUSB	glucuronidase, beta
chr7_-_72936538	0.913		BAZ1B	bromodomain adjacent to zinc finger domain, 1B
chr6_+_30524662	0.868		PRR3	proline rich 3
chr7_-_65447206	0.864		GUSB	glucuronidase, beta
chr4_+_140587086	0.837		MGST2	microsomal glutathione S-transferase 2
chr2_+_219646448	0.828	NM_000784	CYP27A1	cytochrome P450, family 27, subfamily A, polypeptide 1
chrX_-_122866888	0.817	NM_001081550	THOC2	THO complex 2
chr19_+_50016606	0.797		FCGRT	Fc fragment of IgG, receptor, transporter, alpha
chr1_-_173886401	0.788		SERPINC1	serpin peptidase inhibitor, clade C (antithrombin), member 1
chr14_-_95623665	0.776	NM_177438	DICER1	dicer 1, ribonuclease type III
chr20_+_37590969	0.763	NM_001190809 NM_021931	DHX35	DEAH (Asp-Glu-Ala-His) box polypeptide 35
chr2_-_28113211	0.719	NM_022128	RBKS	ribokinase
chr7_-_74489636	0.699		WBSCR16	Williams-Beuren syndrome chromosome region 16
chr1_-_15911461	0.644	NM_024758	AGMAT	agmatine ureohydrolase (agmatinase)
chr1_+_43855599	0.644		SZT2	seizure threshold 2 homolog (mouse)
chr2_+_159313407	0.624		PKP4	plakophilin 4
chr6_+_143999058	0.613	NM_001100164 NM_001100165	PHACTR2	phosphatase and actin regulator 2
chr2_-_207024103	0.573	NM_001199981 NM_001199982 NM_001199983 NM_005006	NDUFS1	NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chrX_-_122866881	0.571		THOC2	THO complex 2
chr2_+_73441344	0.570	NM_006062	SMYD5	SMYD family member 5
chr20_-_36661822	0.552	NM_014657	TTI1	TELO2 interacting protein 1
chr12_-_51422012	0.527	NM_001174125	SLC11A2	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr22_+_41865112	0.503	NM_001098	ACO2	aconitase 2, mitochondrial
chr3_-_52312257	0.499		WDR82	WD repeat domain 82
chr17_-_36105005	0.468	NM_000458 NM_001165923	HNF1B	HNF1 homeobox B
chr22_-_24059524	0.463		GUSBP11	glucuronidase, beta pseudogene 11
chr19_-_41196419	0.457	NM_004756	NUMBL	numb homolog (Drosophila)-like
chr7_-_74489572	0.438		WBSCR16	Williams-Beuren syndrome chromosome region 16
chr18_-_47339854	0.408		ACAA2	acetyl-CoA acyltransferase 2
chr2_+_162016926	0.401	NM_001199135	TANK	TRAF family member-associated NFKB activator
chr11_+_118230292	0.392	NM_001204077 NM_004788	UBE4A	ubiquitination factor E4A
chrX_+_38420690	0.387	NM_004615	TSPAN7	tetraspanin 7
chr7_+_137761177	0.385	NM_001190906 NM_001190907 NM_005989	AKR1D1	aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)
chr1_-_160313029	0.364		COPA	coatomer protein complex, subunit alpha
chr18_-_51750460	0.354		MBD2	methyl-CpG binding domain protein 2
chr1_+_160313061	0.347	NM_015331	NCSTN	nicastrin
chr7_-_74489686	0.343	NM_030798	WBSCR16	Williams-Beuren syndrome chromosome region 16
chr19_+_11546485	0.341		PRKCSH	protein kinase C substrate 80K-H
chr9_+_115142395	0.339		HSDL2	hydroxysteroid dehydrogenase like 2
chr16_-_47007567	0.325	NM_005880	DNAJA2	DnaJ (Hsp40) homolog, subfamily A, member 2
chr2_+_86668270	0.323	NM_018433	KDM3A	lysine (K)-specific demethylase 3A
chr9_+_115142188	0.320	NM_001195822 NM_032303	HSDL2	hydroxysteroid dehydrogenase like 2
chr7_-_72936592	0.316	NM_032408	BAZ1B	bromodomain adjacent to zinc finger domain, 1B
chr22_-_24059436	0.311
chr2_-_198364997	0.305	NM_199440	HSPD1	heat shock 60kDa protein 1 (chaperonin)
chr3_+_150264514	0.303	NM_032025	EIF2A	eukaryotic translation initiation factor 2A, 65kDa
chr11_+_118230348	0.285		UBE4A	ubiquitination factor E4A
chr2_-_198364522	0.285		HSPD1	heat shock 60kDa protein 1 (chaperonin)
chr22_+_25003610	0.283	NM_001032365	GGT1	gamma-glutamyltransferase 1
chr22_-_24059502	0.280		GUSBP11	glucuronidase, beta pseudogene 11
chr19_+_11546085	0.278	NM_001001329 NM_002743	PRKCSH	protein kinase C substrate 80K-H
chr20_+_43160435	0.277	NM_007066 NM_181804 NM_181805	PKIG	protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr1_-_43855448	0.274		MED8	mediator complex subunit 8
chr10_+_114133838	0.257	NM_203379	ACSL5	acyl-CoA synthetase long-chain family member 5
chr4_-_4543690	0.251		STX18	syntaxin 18
chr20_-_34542205	0.251		SCAND1	SCAN domain containing 1
chr22_+_38201113	0.244	NM_005318	H1F0	H1 histone family, member 0
chr4_+_90816002	0.244	NM_007351	MMRN1	multimerin 1
chr12_-_51419923	0.244	NM_001174129	SLC11A2	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr11_+_86748870	0.240	NM_001168724 NM_022918	TMEM135	transmembrane protein 135
chr16_-_21436657	0.238	NM_130464	NPIPL3	nuclear pore complex interacting protein-like 3
chr2_-_198364560	0.235		HSPD1	heat shock 60kDa protein 1 (chaperonin)
chr12_-_51420097	0.228	NM_000617 NM_001174126 NM_001174127 NM_001174128	SLC11A2	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr1_+_78354199	0.221	NM_001172309 NM_144573	NEXN	nexilin (F actin binding protein)
chr3_-_150264264	0.219		SERP1	stress-associated endoplasmic reticulum protein 1
chr1_-_32860014	0.204	NM_001143888 NM_001143889 NM_001143890 NM_018045	BSDC1	BSD domain containing 1
chr2_+_109237679	0.203	NM_001193484	LIMS1	LIM and senescent cell antigen-like domains 1
chr2_-_198364623	0.201	NM_002156	HSPD1	heat shock 60kDa protein 1 (chaperonin)
chr19_+_11546938	0.200		PRKCSH	protein kinase C substrate 80K-H
chr3_-_150264280	0.181	NM_014445	SERP1	stress-associated endoplasmic reticulum protein 1
chr18_-_46477080	0.178	NM_001190821 NM_005904	SMAD7	SMAD family member 7
chr12_-_54121203	0.171	NM_001143682 NM_020898	CALCOCO1	calcium binding and coiled-coil domain 1
chr1_+_45097669	0.170		RNF220	ring finger protein 220
chr9_+_91933384	0.165	NM_024077	SECISBP2	SECIS binding protein 2
chrX_-_64254592	0.162	NM_001178032 NM_001243804	ZC4H2	zinc finger, C4H2 domain containing
chr8_-_145550300	0.160		DGAT1	diacylglycerol O-acyltransferase 1
chr17_+_7123246	0.159		ACADVL	acyl-CoA dehydrogenase, very long chain
chr22_+_47158517	0.159	NM_014346	TBC1D22A	TBC1 domain family, member 22A
chr16_-_47007483	0.158		DNAJA2	DnaJ (Hsp40) homolog, subfamily A, member 2
chr3_-_49314281	0.158	NM_198562	C3orf62	chromosome 3 open reading frame 62
chr1_-_19578015	0.154		KIAA0090	KIAA0090
chr20_-_34542385	0.152	NM_033630	SCAND1	SCAN domain containing 1
chr15_+_96873845	0.151	NM_021005	NR2F2	nuclear receptor subfamily 2, group F, member 2
chr7_+_120628722	0.150	NM_024913	C7orf58	chromosome 7 open reading frame 58
chr12_+_107168336	0.149	NM_018157	RIC8B	resistance to inhibitors of cholinesterase 8 homolog B (C. elegans)
chr1_-_79472360	0.149	NM_022159	ELTD1	EGF, latrophilin and seven transmembrane domain containing 1
chr12_+_121416548	0.148	NM_000545	HNF1A	HNF1 homeobox A
chr15_+_57210852	0.146		TCF12	transcription factor 12
chrX_-_1510901	0.145	NM_001636	SLC25A6	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
chr22_+_24115035	0.145	NM_005940	MMP11	matrix metallopeptidase 11 (stromelysin 3)
chr22_-_31742329	0.142		PATZ1	POZ (BTB) and AT hook containing zinc finger 1
chr20_+_44509847	0.142	NM_080603	ZSWIM1	zinc finger, SWIM-type containing 1
chr11_+_117049838	0.139	NM_001040455	SIDT2	SID1 transmembrane family, member 2
chr18_-_47340208	0.137	NM_006111	ACAA2	acetyl-CoA acyltransferase 2
chr11_-_62414063	0.136		GANAB	glucosidase, alpha; neutral AB
chr11_+_118443091	0.129	NM_001142281 NM_001655	ARCN1	archain 1
chr1_+_150337145	0.123		RPRD2	regulation of nuclear pre-mRNA domain containing 2
chr3_+_184056304	0.122		FAM131A	family with sequence similarity 131, member A
chr1_-_226374400	0.120		ACBD3	acyl-CoA binding domain containing 3
chr1_-_226374401	0.120	NM_022735	ACBD3	acyl-CoA binding domain containing 3
chr11_+_118443140	0.117		ARCN1	archain 1
chr2_+_207024317	0.117	NM_001037663 NM_001959 NM_021121	EEF1B2	eukaryotic translation elongation factor 1 beta 2
chr19_+_1205773	0.112	NM_000455	STK11	serine/threonine kinase 11
chr1_+_36396673	0.109	NM_024852 NM_177422	EIF2C3	eukaryotic translation initiation factor 2C, 3
chr20_-_54967221	0.108	NM_003600 NM_198433 NM_198434 NM_198435 NM_198436 NM_198437	AURKA	aurora kinase A
chr16_-_30596808	0.108	NM_152458	ZNF785	zinc finger protein 785
chr12_+_96252705	0.107	NM_003095	SNRPF	small nuclear ribonucleoprotein polypeptide F
chr12_-_7079616	0.107		PHB2	prohibitin 2
chr2_+_198365113	0.106		HSPE1	heat shock 10kDa protein 1 (chaperonin 10)
chr2_+_207024614	0.104		EEF1B2	eukaryotic translation elongation factor 1 beta 2
chrY_-_1460901	0.101	NM_001636	SLC25A6	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
chr1_-_19578030	0.101		KIAA0090	KIAA0090
chr19_+_11546447	0.101		PRKCSH	protein kinase C substrate 80K-H
chr11_-_62414086	0.100		GANAB	glucosidase, alpha; neutral AB
chr14_+_24867926	0.097	NM_025081	NYNRIN	NYN domain and retroviral integrase containing
chr2_+_28113612	0.097		BRE	brain and reproductive organ-expressed (TNFRSF1A modulator)
chr19_+_11546467	0.097		PRKCSH	protein kinase C substrate 80K-H
chr1_-_111970354	0.096	NM_002557	OVGP1	oviductal glycoprotein 1, 120kDa
chr14_-_106174914	0.095		IGHA1	immunoglobulin heavy constant alpha 1
chr6_-_30523933	0.094		GNL1	guanine nucleotide binding protein-like 1
chr2_+_28113655	0.091		BRE	brain and reproductive organ-expressed (TNFRSF1A modulator)
chr1_-_19578045	0.091	NM_015047	KIAA0090	KIAA0090
chr5_-_32444729	0.089		ZFR	zinc finger RNA binding protein
chr10_+_120967094	0.087	NM_005308	GRK5	G protein-coupled receptor kinase 5
chr2_+_198365012	0.085		HSPE1	heat shock 10kDa protein 1 (chaperonin 10)
chr3_+_139654001	0.084	NM_022131	CLSTN2	calsyntenin 2
chr8_-_145550516	0.082		DGAT1	diacylglycerol O-acyltransferase 1
chr12_+_121416294	0.082		HNF1A	HNF1 homeobox A
chr17_+_7123149	0.076	NM_000018 NM_001033859	ACADVL	acyl-CoA dehydrogenase, very long chain
chr19_-_36303724	0.073		PRODH2	proline dehydrogenase (oxidase) 2
chr20_+_42187634	0.071	NM_170693	SGK2	serum/glucocorticoid regulated kinase 2
chr2_+_28113481	0.069	NM_199193 NM_199194 NM_004899 NM_199191 NM_199192	BRE	brain and reproductive organ-expressed (TNFRSF1A modulator)
chr20_+_54967572	0.069	NM_001324	CSTF1	cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
chr19_+_39390570	0.068		NFKBIB	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr17_+_7533452	0.067	NM_001040 NM_001146279 NM_001146280 NM_001146281	SHBG	sex hormone-binding globulin
chr12_+_49716970	0.066	NM_001100620 NM_005480	TROAP	trophinin associated protein (tastin)
chr15_+_57210823	0.065	NM_003205 NM_207036 NM_207037 NM_207038	TCF12	transcription factor 12
chr7_+_100318422	0.063	NM_000799	EPO	erythropoietin
chr17_+_45973515	0.061	NM_003110	SP2	Sp2 transcription factor
chr16_+_30710461	0.058	NM_006662	SRCAP	Snf2-related CREBBP activator protein
chr2_-_220034706	0.058	NM_001144889 NM_001144890 NM_144712	SLC23A3	solute carrier family 23 (nucleobase transporters), member 3
chr8_-_145550536	0.051	NM_012079	DGAT1	diacylglycerol O-acyltransferase 1
chrX_+_105937067	0.051	NM_024539	RNF128	ring finger protein 128
chr15_+_57210972	0.051		TCF12	transcription factor 12
chr20_+_55108265	0.050	NM_001013646	FAM209B	family with sequence similarity 209, member B
chr4_+_156680603	0.049		GUCY1B3	guanylate cyclase 1, soluble, beta 3
chr10_+_75504145	0.049		SEC24C	SEC24 family, member C (S. cerevisiae)
chr10_+_75504119	0.045	NM_004922 NM_198597	SEC24C	SEC24 family, member C (S. cerevisiae)
chr16_-_30546145	0.045	NM_023931	ZNF747	zinc finger protein 747
chr8_+_67624652	0.044	NM_001033578	SGK3	serum/glucocorticoid regulated kinase family, member 3
chr2_-_74756824	0.044		AUP1	ancient ubiquitous protein 1
chr2_-_74756823	0.043		AUP1	ancient ubiquitous protein 1
chr7_-_74306672	0.043		STAG3L2	stromal antigen 3-like 2
chr5_-_176981537	0.041	NM_001190946	FAM193B	family with sequence similarity 193, member B
chr1_-_211848820	0.041	NM_001204182 NM_001204183 NM_002497	NEK2	NIMA (never in mitosis gene a)-related kinase 2
chr4_-_4543747	0.041	NM_016930	STX18	syntaxin 18
chr13_+_21714709	0.041		SAP18	Sin3A-associated protein, 18kDa
chr2_-_74756815	0.037		AUP1	ancient ubiquitous protein 1
chr2_-_74756838	0.034		AUP1	ancient ubiquitous protein 1
chr12_+_69202796	0.031		MDM2	Mdm2 p53 binding protein homolog (mouse)
chr2_+_74756986	0.030		HTRA2	HtrA serine peptidase 2
chr6_+_96025343	0.028	NM_024641	MANEA	mannosidase, endo-alpha
chr12_+_67663147	0.028		CAND1	cullin-associated and neddylation-dissociated 1
chr15_-_83680369	0.028	NM_001160113 NM_001160114 NM_001160115 NM_001160116 NM_144597	C15orf40	chromosome 15 open reading frame 40
chr8_+_67624941	0.028		SGK3	serum/glucocorticoid regulated kinase family, member 3
chr9_+_140513451	0.026		EHMT1	euchromatic histone-lysine N-methyltransferase 1
chr2_+_74757243	0.025		HTRA2	HtrA serine peptidase 2
chr2_+_74757127	0.025		HTRA2	HtrA serine peptidase 2
chr1_-_160312959	0.025

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
137.52	2.00e-04	GO:0034377	plasma lipoprotein particle assembly
137.52	2.00e-04	GO:0065005	protein-lipid complex assembly
117.88	3.29e-04	GO:0034375	high-density lipoprotein particle remodeling
97.09	6.13e-04	GO:0043691	reverse cholesterol transport
86.87	8.72e-04	GO:0034381	plasma lipoprotein particle clearance
82.53	1.02e-03	GO:0033344	cholesterol efflux
78.60	1.19e-03	GO:0034367	macromolecular complex remodeling
78.60	1.19e-03	GO:0034368	protein-lipid complex remodeling
78.60	1.19e-03	GO:0034369	plasma lipoprotein particle remodeling
366.65	1.72e-03	GO:0010903	negative regulation of very-low-density lipoprotein particle remodeling
66.03	2.06e-03	GO:0071825	protein-lipid complex subunit organization
66.03	2.06e-03	GO:0071827	plasma lipoprotein particle organization
275.00	3.44e-03	GO:0010901	regulation of very-low-density lipoprotein particle remodeling
275.00	3.44e-03	GO:0032488	Cdc42 protein signal transduction
48.57	5.29e-03	GO:0097006	regulation of plasma lipoprotein particle levels
220.01	5.73e-03	GO:0034380	high-density lipoprotein particle assembly
43.46	7.43e-03	GO:0030301	cholesterol transport
42.34	8.04e-03	GO:0015918	sterol transport
183.35	8.59e-03	GO:0034384	high-density lipoprotein particle clearance
38.41	1.08e-02	GO:0042632	cholesterol homeostasis
38.41	1.08e-02	GO:0055092	sterol homeostasis
122.25	2.05e-02	GO:0033700	phospholipid efflux
28.49	2.66e-02	GO:0055088	lipid homeostasis
13.22	3.60e-02	GO:0046486	glycerolipid metabolic process

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
206.26	1.22e-05	GO:0034366	spherical high-density lipoprotein particle
91.70	1.76e-04	GO:0034361	very-low-density lipoprotein particle
91.70	1.76e-04	GO:0034385	triglyceride-rich lipoprotein particle
75.03	3.31e-04	GO:0034364	high-density lipoprotein particle
51.60	1.05e-03	GO:0032994	protein-lipid complex
51.60	1.05e-03	GO:0034358	plasma lipoprotein particle

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
366.65	3.78e-04	GO:0070653	high-density lipoprotein particle receptor binding