Motif ID: SNAI1..3.p2

Z-value: 4.658


Transcription factors associated with SNAI1..3.p2:

Gene SymbolEntrez IDGene Name
SNAI1 6615 snail homolog 1 (Drosophila)
SNAI2 6591 snail homolog 2 (Drosophila)
SNAI3 333929 snail homolog 3 (Drosophila)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
SNAI1chr20_+_48599511-0.233.9e-01Click!
SNAI2chr8_-_498338230.234.0e-01Click!


Activity profile for motif SNAI1..3.p2.

activity profile for motif SNAI1..3.p2


Sorted Z-values histogram for motif SNAI1..3.p2

Sorted Z-values for motif SNAI1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SNAI1..3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_+_38755238 15.972 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr19_+_38755422 15.332 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr2_-_166650770 15.239 NM_004482
 GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr1_+_183155393 14.819 LAMC2
laminin, gamma 2
chr19_+_38755097 13.348 NM_001166103
NM_021102
 SPINT2

serine peptidase inhibitor, Kunitz type, 2

chr16_+_68679229 12.505 CDH3
cadherin 3, type 1, P-cadherin (placental)
chr4_+_75310852 10.696 NM_001657
 AREG
amphiregulin
chr1_+_183155361 9.871 LAMC2
laminin, gamma 2
chr1_+_183155173 9.398 NM_005562
NM_018891
 LAMC2

laminin, gamma 2

chr14_-_67878859 9.079 PLEK2
pleckstrin 2
chr14_-_67878770 8.934 NM_016445
 PLEK2
pleckstrin 2
chr14_-_61748510 8.713 NM_001017970
 TMEM30B
transmembrane protein 30B
chr18_+_21452981 8.445 NM_000227
NM_001127718
 LAMA3

laminin, alpha 3

chr1_+_46646199 8.203 TSPAN1
tetraspanin 1
chr20_-_6103562 7.679 FERMT1
fermitin family member 1
chr17_-_39942937 7.666 NM_002230
NM_021991
 JUP

junction plakoglobin

chr16_-_4987056 7.634 NM_002705
 PPL
periplakin
chr11_+_121322848 6.784 NM_003105
 SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr16_+_68771192 6.718 NM_004360
 CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chr14_-_61747956 6.712 TMEM30B
transmembrane protein 30B

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 17 of 17 entries
Enrichment   P-value GO Accession GO Term
34.25 2.28e-07 GO:0031581 hemidesmosome assembly
29.36 1.75e-05 GO:0043616 keratinocyte proliferation
13.46 6.27e-04 GO:0007044 cell-substrate junction assembly
9.79 1.32e-03 GO:0030216 keratinocyte differentiation
8.28 4.93e-03 GO:0009913 epidermal cell differentiation
7.94 1.12e-11 GO:0008544 epidermis development
5.15 9.77e-03 GO:0034329 cell junction assembly
5.13 3.98e-03 GO:0034330 cell junction organization
4.43 1.82e-02 GO:0030855 epithelial cell differentiation
3.87 1.18e-04 GO:0060429 epithelium development
3.22 3.68e-08 GO:0009888 tissue development
2.60 4.33e-02 GO:0006928 cellular component movement
1.88 4.00e-03 GO:0048513 organ development
1.63 3.62e-03 GO:0048856 anatomical structure development
1.59 4.10e-02 GO:0048731 system development
1.53 4.34e-02 GO:0007275 multicellular organismal development
1.44 7.99e-03 GO:0032501 multicellular organismal process

Gene overrepresentation in compartment category:

Showing 1 to 13 of 13 entries
Enrichment   P-value GO Accession GO Term
20.93 3.64e-06 GO:0030057 desmosome
13.05 2.27e-05 GO:0045095 keratin filament
7.40 4.68e-05 GO:0005882 intermediate filament
5.87 5.05e-04 GO:0045111 intermediate filament cytoskeleton
4.74 2.91e-04 GO:0005911 cell-cell junction
4.40 3.60e-03 GO:0070161 anchoring junction
3.68 5.51e-03 GO:0016323 basolateral plasma membrane
2.11 4.97e-02 GO:0005615 extracellular space
1.77 9.80e-04 GO:0044459 plasma membrane part
1.74 2.17e-02 GO:0005576 extracellular region
1.60 1.66e-04 GO:0005886 plasma membrane
1.58 3.22e-04 GO:0071944 cell periphery
1.31 8.10e-03 GO:0016020 membrane

Gene overrepresentation in function category:

Showing 1 to 4 of 4 entries
Enrichment   P-value GO Accession GO Term
17.94 1.10e-02 GO:0005154 epidermal growth factor receptor binding
6.92 1.15e-03 GO:0005200 structural constituent of cytoskeleton
2.77 5.09e-04 GO:0005198 structural molecule activity
2.52 4.03e-03 GO:0005509 calcium ion binding