Motif ID: SOX2.p2

Z-value: 1.047


Transcription factors associated with SOX2.p2:

Gene SymbolEntrez IDGene Name
SOX2 6657 SRY (sex determining region Y)-box 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
SOX2chr3_+_181430075-0.562.5e-02Click!


Activity profile for motif SOX2.p2.

activity profile for motif SOX2.p2


Sorted Z-values histogram for motif SOX2.p2

Sorted Z-values for motif SOX2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SOX2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_102553343 2.312 NM_001031692
NM_005824
 LRRC17

leucine rich repeat containing 17

chr10_+_11207053 2.114 CELF2
CUGBP, Elav-like family member 2
chr2_+_33359607 1.991 NM_000627
NM_001166264
NM_001166265
NM_001166266
 LTBP1



latent transforming growth factor beta binding protein 1



chr18_-_53177999 1.889 NM_001243231
 TCF4
transcription factor 4
chr10_+_70847817 1.754 NM_002727
 SRGN
serglycin
chr10_+_11206928 1.677 NM_001025076
NM_001083591
 CELF2

CUGBP, Elav-like family member 2

chr5_-_39424930 1.640 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr1_+_84647342 1.618 NM_001242862
 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr1_-_32801606 1.576 NM_023009
 MARCKSL1
MARCKS-like 1
chrX_+_15518899 1.574 NM_203281
 BMX
BMX non-receptor tyrosine kinase
chr10_+_70847857 1.562 SRGN
serglycin
chr4_-_101439071 1.546 NM_001159694
NM_016242
 EMCN

endomucin

chr10_+_11047274 1.465 CELF2
CUGBP, Elav-like family member 2
chr4_+_41258941 1.400 UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr2_-_188312872 1.384 NM_005795
 CALCRL
calcitonin receptor-like
chr5_+_15500288 1.381 NM_012304
 FBXL7
F-box and leucine-rich repeat protein 7
chr18_-_52988916 1.370 NM_001243234
NM_001243235
 TCF4

transcription factor 4

chr10_+_11047253 1.224 NM_001025077
 CELF2
CUGBP, Elav-like family member 2
chr1_-_173174611 1.190 TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr1_+_86046434 1.161 NM_001554
 CYR61
cysteine-rich, angiogenic inducer, 61

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 15 of 15 entries
Enrichment   P-value GO Accession GO Term
468.48 1.59e-03 GO:0048014 Tie receptor signaling pathway
31.27 4.07e-02 GO:0010594 regulation of endothelial cell migration
12.30 1.51e-02 GO:0048514 blood vessel morphogenesis
10.13 3.81e-02 GO:0001568 blood vessel development
8.32 4.45e-03 GO:0072358 cardiovascular system development
8.32 4.45e-03 GO:0072359 circulatory system development
7.49 2.00e-03 GO:0042060 wound healing
6.78 1.67e-02 GO:0050878 regulation of body fluid levels
5.60 4.83e-03 GO:0009611 response to wounding
4.42 3.69e-03 GO:0009653 anatomical structure morphogenesis
3.51 3.28e-02 GO:0048583 regulation of response to stimulus
3.06 1.37e-03 GO:0048856 anatomical structure development
2.97 1.33e-02 GO:0048731 system development
2.69 1.94e-02 GO:0007275 multicellular organismal development
2.60 1.27e-02 GO:0032502 developmental process

Gene overrepresentation in compartment category:

Showing 1 to 3 of 3 entries
Enrichment   P-value GO Accession GO Term
5.67 2.54e-03 GO:0005615 extracellular space
5.63 2.10e-04 GO:0044421 extracellular region part
3.98 5.93e-04 GO:0005576 extracellular region

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
Enrichment   P-value GO Accession GO Term
70.30 4.22e-04 GO:0030971 receptor tyrosine kinase binding
40.19 2.37e-03 GO:0005518 collagen binding
5.02 1.45e-03 GO:0005102 receptor binding