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Motif ID: SOX2.p2

Z-value: 1.047

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr7_+_102553343	2.312	NM_001031692 NM_005824	LRRC17	leucine rich repeat containing 17
chr10_+_11207053	2.114		CELF2	CUGBP, Elav-like family member 2
chr2_+_33359607	1.991	NM_000627 NM_001166264 NM_001166265 NM_001166266	LTBP1	latent transforming growth factor beta binding protein 1
chr18_-_53177999	1.889	NM_001243231	TCF4	transcription factor 4
chr10_+_70847817	1.754	NM_002727	SRGN	serglycin
chr10_+_11206928	1.677	NM_001025076 NM_001083591	CELF2	CUGBP, Elav-like family member 2
chr5_-_39424930	1.640		DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr1_+_84647342	1.618	NM_001242862	PRKACB	protein kinase, cAMP-dependent, catalytic, beta
chr1_-_32801606	1.576	NM_023009	MARCKSL1	MARCKS-like 1
chrX_+_15518899	1.574	NM_203281	BMX	BMX non-receptor tyrosine kinase
chr10_+_70847857	1.562		SRGN	serglycin
chr4_-_101439071	1.546	NM_001159694 NM_016242	EMCN	endomucin
chr10_+_11047274	1.465		CELF2	CUGBP, Elav-like family member 2
chr4_+_41258941	1.400		UCHL1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr2_-_188312872	1.384	NM_005795	CALCRL	calcitonin receptor-like
chr5_+_15500288	1.381	NM_012304	FBXL7	F-box and leucine-rich repeat protein 7
chr18_-_52988916	1.370	NM_001243234 NM_001243235	TCF4	transcription factor 4
chr10_+_11047253	1.224	NM_001025077	CELF2	CUGBP, Elav-like family member 2
chr1_-_173174611	1.190		TNFSF4	tumor necrosis factor (ligand) superfamily, member 4
chr1_+_86046434	1.161	NM_001554	CYR61	cysteine-rich, angiogenic inducer, 61
chr12_-_6233684	1.157	NM_000552	VWF	von Willebrand factor
chr18_+_72922725	1.151	NM_005786	TSHZ1	teashirt zinc finger homeobox 1
chr12_-_91573264	1.143	NM_133503	DCN	decorin
chr7_-_111846384	1.113	NM_014705	DOCK4	dedicator of cytokinesis 4
chr22_-_19512859	1.106	NM_001130861 NM_003277	CLDN5	claudin 5
chr8_-_6420454	1.098	NM_001118887 NM_001118888 NM_001147	ANGPT2	angiopoietin 2
chr6_+_12290528	1.073	NM_001168319 NM_001955	EDN1	endothelin 1
chr4_+_41258909	1.070		UCHL1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr5_-_111091947	1.069	NM_001142483	C5orf13	chromosome 5 open reading frame 13
chr7_+_93551015	1.062	NM_004126	GNG11	guanine nucleotide binding protein (G protein), gamma 11
chr4_+_41258895	1.054	NM_004181	UCHL1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr5_-_39425297	1.040	NM_001244871 NM_001343	DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr2_+_189839132	1.018		COL3A1	collagen, type III, alpha 1
chr6_+_121756744	1.007	NM_000165	GJA1	gap junction protein, alpha 1, 43kDa
chr8_-_108510094	1.002	NM_001146 NM_001199859	ANGPT1	angiopoietin 1
chr3_+_151986731	0.999		MBNL1	muscleblind-like (Drosophila)
chrX_+_100333835	0.988	NM_021637	TMEM35	transmembrane protein 35
chr5_-_39425030	0.974		DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr5_-_88199868	0.932	NM_001131005 NM_001193347	MEF2C	myocyte enhancer factor 2C
chr13_-_110959441	0.929	NM_001845	COL4A1	collagen, type IV, alpha 1
chr18_-_52969714	0.911	NM_001243236	TCF4	transcription factor 4
chr1_+_171154387	0.899	NM_001460	FMO2	flavin containing monooxygenase 2 (non-functional)
chr7_-_131241321	0.896	NM_001018111 NM_005397	PODXL	podocalyxin-like
chrX_+_100805415	0.890	NM_016608	ARMCX1	armadillo repeat containing, X-linked 1
chr15_-_23932410	0.883	NM_002487	NDN	necdin homolog (mouse)
chr7_-_27205148	0.880	NM_152739	HOXA9	homeobox A9
chr1_-_68697997	0.879	NM_001002292 NM_001193334 NM_024911	WLS	wntless homolog (Drosophila)
chr2_-_190044330	0.862	NM_000393	COL5A2	collagen, type V, alpha 2
chr1_+_183605207	0.858	NM_015149	RGL1	ral guanine nucleotide dissociation stimulator-like 1
chr16_+_66400524	0.852	NM_001795	CDH5	cadherin 5, type 2 (vascular endothelium)
chr1_+_81771844	0.838		LPHN2	latrophilin 2
chr18_-_53257033	0.835	NM_001243227 NM_001243228	TCF4	transcription factor 4
chr5_+_34687663	0.831	NM_001145523	RAI14	retinoic acid induced 14
chr10_+_17270469	0.828		VIM	vimentin
chr10_+_17271302	0.823		VIM	vimentin
chr1_+_66797775	0.818	NM_001037339	PDE4B	phosphodiesterase 4B, cAMP-specific
chr10_+_17271276	0.816		VIM	vimentin
chr10_+_17271277	0.816		VIM	vimentin
chr6_-_32163890	0.815		NOTCH4	notch 4
chr18_-_53089722	0.814	NM_001243233	TCF4	transcription factor 4
chr9_+_36036900	0.808	NM_021111	RECK	reversion-inducing-cysteine-rich protein with kazal motifs
chrX_+_12994286	0.786		TMSB4X	thymosin beta 4, X-linked
chrX_+_80457302	0.785	NM_003022	SH3BGRL	SH3 domain binding glutamic acid-rich protein like
chr6_-_139695739	0.778		CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chrX_+_15525430	0.768	NM_001721	BMX	BMX non-receptor tyrosine kinase
chr9_-_16727887	0.766		BNC2	basonuclin 2
chrX_+_135251454	0.755	NM_001159704	FHL1	four and a half LIM domains 1
chr4_+_146403955	0.753	NM_001003688	SMAD1	SMAD family member 1
chrX_+_135251795	0.749	NM_001167819	FHL1	four and a half LIM domains 1
chr1_+_100111430	0.745	NM_017734	PALMD	palmdelphin
chr1_+_151032866	0.741		MLLT11	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr1_+_151032880	0.733		MLLT11	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chrX_+_12993224	0.730	NM_021109	TMSB4X	thymosin beta 4, X-linked
chr15_-_83876769	0.729		HDGFRP3	hepatoma-derived growth factor, related protein 3
chr11_+_5710926	0.727		TRIM22	tripartite motif containing 22
chr6_+_153019029	0.722	NM_025107	MYCT1	myc target 1
chr6_-_112575880	0.716		LAMA4	laminin, alpha 4
chrX_+_80457597	0.709		SH3BGRL	SH3 domain binding glutamic acid-rich protein like
chr3_-_168864325	0.706	NM_001105078	MECOM	MDS1 and EVI1 complex locus
chr1_-_26233367	0.703	NM_203399	STMN1	stathmin 1
chrX_+_80457559	0.697		SH3BGRL	SH3 domain binding glutamic acid-rich protein like
chr1_+_66458389	0.695	NM_001037340	PDE4B	phosphodiesterase 4B, cAMP-specific
chr11_+_46402333	0.695	NM_001012334	MDK	midkine (neurite growth-promoting factor 2)
chr7_-_107643330	0.690	NM_002291	LAMB1	laminin, beta 1
chr5_+_95066628	0.686	NM_014899	RHOBTB3	Rho-related BTB domain containing 3
chr9_+_101705710	0.685	NM_001855	COL15A1	collagen, type XV, alpha 1
chr12_+_49212253	0.683	NM_000725 NM_001206915	CACNB3	calcium channel, voltage-dependent, beta 3 subunit
chr1_+_151032683	0.679		MLLT11	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr2_-_151344145	0.676	NM_005168	RND3	Rho family GTPase 3
chr8_-_93029864	0.674	NM_175636	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr1_+_155853546	0.669		SYT11	synaptotagmin XI
chr2_-_217540722	0.667		IGFBP5	insulin-like growth factor binding protein 5
chr15_+_67358194	0.665	NM_005902	SMAD3	SMAD family member 3
chrX_-_11284094	0.650	NM_013423	ARHGAP6	Rho GTPase activating protein 6
chr1_+_163038564	0.646	NM_005613	RGS4	regulator of G-protein signaling 4
chr1_-_85930610	0.644		DDAH1	dimethylarginine dimethylaminohydrolase 1
chr6_-_27440459	0.642	NM_007149	ZNF184	zinc finger protein 184
chr12_-_91576579	0.642		DCN	decorin
chr9_+_116342939	0.622	NM_021106	RGS3	regulator of G-protein signaling 3
chr9_+_116343169	0.611		RGS3	regulator of G-protein signaling 3
chr12_+_14538232	0.610		ATF7IP	activating transcription factor 7 interacting protein
chr1_+_163038934	0.610	NM_001113381	RGS4	regulator of G-protein signaling 4
chr6_-_139695784	0.607	NM_006079	CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr3_-_120169493	0.606	NM_007085	FSTL1	follistatin-like 1
chr14_+_105941061	0.605	NM_001312	CRIP2	cysteine-rich protein 2
chr9_+_116263706	0.604	NM_130795	RGS3	regulator of G-protein signaling 3
chr18_-_53255361	0.599		TCF4	transcription factor 4
chr5_+_102465256	0.594	NM_015216	PPIP5K2	diphosphoinositol pentakisphosphate kinase 2
chr14_-_92414004	0.591	NM_006329	FBLN5	fibulin 5
chr1_-_226926875	0.589	NM_002221	ITPKB	inositol-trisphosphate 3-kinase B
chr8_-_82395401	0.588	NM_001442	FABP4	fatty acid binding protein 4, adipocyte
chrX_+_135229536	0.587	NM_001159702 NM_001159703 NM_001449	FHL1	four and a half LIM domains 1
chr8_-_119964059	0.587	NM_002546	TNFRSF11B	tumor necrosis factor receptor superfamily, member 11b
chr15_+_96869156	0.587	NM_001145155	NR2F2	nuclear receptor subfamily 2, group F, member 2
chr1_-_47695442	0.580	NM_003189	TAL1	T-cell acute lymphocytic leukemia 1
chr5_+_71502700	0.579		MAP1B	microtubule-associated protein 1B
chr4_+_90816002	0.567	NM_007351	MMRN1	multimerin 1
chr1_-_95392501	0.559	NM_001839	CNN3	calponin 3, acidic
chr1_+_43766565	0.547	NM_001253357 NM_005424	TIE1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr4_+_86851425	0.541	NM_031305	ARHGAP24	Rho GTPase activating protein 24
chr5_-_111092918	0.540	NM_004772	C5orf13	chromosome 5 open reading frame 13
chr1_+_196621007	0.535	NM_000186 NM_001014975	CFH	complement factor H
chr14_-_92413738	0.533		FBLN5	fibulin 5
chr8_+_79428335	0.533	NM_006823 NM_181839	PKIA	protein kinase (cAMP-dependent, catalytic) inhibitor alpha
chr7_+_134464417	0.529		CALD1	caldesmon 1
chr8_-_93115453	0.528	NM_001198633 NM_175634	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr8_-_93107442	0.525	NM_001198629 NM_001198630 NM_001198632 NM_175635	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr10_-_88717319	0.525	NM_024756	MMRN2	multimerin 2
chr14_+_77228132	0.524	NM_014909	VASH1	vasohibin 1
chr13_-_24007822	0.522	NM_014363	SACS	spastic ataxia of Charlevoix-Saguenay (sacsin)
chr10_+_45496272	0.521	NM_006963	ZNF22	zinc finger protein 22 (KOX 15)
chr19_-_11305186	0.515	NM_015493	KANK2	KN motif and ankyrin repeat domains 2
chr1_-_110283659	0.513	NM_000849	GSTM3	glutathione S-transferase mu 3 (brain)
chr11_-_6676851	0.512	NM_003737	DCHS1	dachsous 1 (Drosophila)
chr13_+_111137249	0.511		COL4A2	collagen, type IV, alpha 2
chr12_+_112204690	0.510	NM_000690 NM_001204889	ALDH2	aldehyde dehydrogenase 2 family (mitochondrial)
chr2_-_175869910	0.506	NM_001822 NM_001025201	CHN1	chimerin (chimaerin) 1
chr12_-_10251520	0.506	NM_016511	CLEC1A	C-type lectin domain family 1, member A
chr5_-_150521200	0.494	NM_001193544	ANXA6	annexin A6
chr3_-_69037498	0.491		C3orf64	chromosome 3 open reading frame 64
chr21_+_35190586	0.491		ITSN1	intersectin 1 (SH3 domain protein)
chr8_-_17579729	0.489	NM_001001931	MTUS1	microtubule associated tumor suppressor 1
chr3_+_173116243	0.489	NM_014932	NLGN1	neuroligin 1
chr18_-_53255734	0.488	NM_001083962 NM_001243230 NM_003199	TCF4	transcription factor 4
chr13_-_99630243	0.488	NM_001130048 NM_001130050	DOCK9	dedicator of cytokinesis 9
chr6_-_167040700	0.480	NM_021135	RPS6KA2	ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr9_+_103235489	0.479	NM_003692	TMEFF1	transmembrane protein with EGF-like and two follistatin-like domains 1
chr6_-_139695349	0.476	NM_001168389 NM_001168388	CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chrX_+_86772714	0.476	NM_019117 NM_057162	KLHL4	kelch-like 4 (Drosophila)
chr3_-_114790221	0.473	NM_001164343	ZBTB20	zinc finger and BTB domain containing 20
chr15_-_23932364	0.473
chr17_-_33759518	0.471	NM_018042	SLFN12	schlafen family member 12
chr5_-_176900653	0.469	NM_004395	DBN1	drebrin 1
chr12_+_93963597	0.467	NM_003877	SOCS2	suppressor of cytokine signaling 2
chr2_-_218843541	0.462		TNS1	tensin 1
chr9_+_103204187	0.461	NM_001198812	C9orf30-TMEFF1 C9orf30	C9orf30-TMEFF1 readthrough chromosome 9 open reading frame 30
chr2_+_74120132	0.460		ACTG2	actin, gamma 2, smooth muscle, enteric
chr5_-_111092865	0.460		C5orf13	chromosome 5 open reading frame 13
chr9_-_14313899	0.457		NFIB	nuclear factor I/B
chr16_-_4896197	0.451		GLYR1	glyoxylate reductase 1 homolog (Arabidopsis)
chr6_-_46293404	0.451		RCAN2	regulator of calcineurin 2
chr7_-_27205123	0.451		HOXA9	homeobox A9
chr9_-_14398981	0.450	NM_001190738	NFIB	nuclear factor I/B
chr1_-_86043932	0.449	NM_001134445	DDAH1	dimethylarginine dimethylaminohydrolase 1
chrX_+_99899162	0.449	NM_014467	SRPX2	sushi-repeat containing protein, X-linked 2
chrX_+_99899388	0.448		SRPX2	sushi-repeat containing protein, X-linked 2
chr16_+_58534045	0.447	NM_001242833 NM_001242834 NM_001242835 NM_001242836	NDRG4	NDRG family member 4
chr9_+_4490193	0.447	NM_004170	SLC1A1	solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
chr5_-_176900591	0.446		DBN1	drebrin 1
chr5_-_39394423	0.446		DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr21_+_37507209	0.446	NM_001236	CBR3	carbonyl reductase 3
chr1_-_159895258	0.444		TAGLN2	transgelin 2
chr15_-_90347534	0.434		ANPEP	alanyl (membrane) aminopeptidase
chr8_+_70405027	0.433	NM_001128205 NM_001128206	SULF1	sulfatase 1
chr2_-_70475563	0.433	NM_022037 NM_022173	TIA1	TIA1 cytotoxic granule-associated RNA binding protein
chrX_+_51927918	0.430	NM_001098800 NM_001242362 NM_030801 NM_177535 NM_177537	MAGED4 MAGED4B	melanoma antigen family D, 4 melanoma antigen family D, 4B
chr18_+_32073343	0.426		DTNA	dystrobrevin, alpha
chr2_+_74120092	0.425	NM_001199893 NM_001615	ACTG2	actin, gamma 2, smooth muscle, enteric
chr4_-_186732047	0.425	NM_001145672	SORBS2	sorbin and SH3 domain containing 2
chr2_+_110656008	0.425	NM_001205288 NM_033514	LIMS3-LOC440895 LIMS3L LIMS3	LIMS3-LOC440895 readthrough LIM and senescent cell antigen-like domains 3-like LIM and senescent cell antigen-like domains 3
chr1_-_201476218	0.422		CSRP1	cysteine and glycine-rich protein 1
chr8_+_70405080	0.420		SULF1	sulfatase 1
chr2_+_189157551	0.420		GULP1	GULP, engulfment adaptor PTB domain containing 1
chr7_+_22767101	0.417		IL6	interleukin 6 (interferon, beta 2)
chr7_-_11871735	0.416	NM_015204	THSD7A	thrombospondin, type I, domain containing 7A
chrX_-_100872926	0.416	NM_001009584 NM_001184768 NM_019007	ARMCX6	armadillo repeat containing, X-linked 6
chr8_-_93075190	0.411	NM_004349	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr2_-_111230651	0.411	NM_001205288 NM_033514	LIMS3-LOC440895 LIMS3L LIMS3	LIMS3-LOC440895 readthrough LIM and senescent cell antigen-like domains 3-like LIM and senescent cell antigen-like domains 3
chr7_+_22766765	0.409	NM_000600	IL6	interleukin 6 (interferon, beta 2)
chr12_+_112204711	0.408		ALDH2	aldehyde dehydrogenase 2 family (mitochondrial)
chr16_+_58497628	0.407		NDRG4	NDRG family member 4
chr15_-_83876165	0.407	NM_016073	HDGFRP3	hepatoma-derived growth factor, related protein 3
chr16_+_58497548	0.406	NM_020465	NDRG4	NDRG family member 4
chr3_+_113616317	0.405	NM_001172105	GRAMD1C	GRAM domain containing 1C
chr3_-_15373807	0.401		SH3BP5	SH3-domain binding protein 5 (BTK-associated)
chr9_-_14086901	0.399		NFIB	nuclear factor I/B
chr10_+_105005643	0.398	NM_001143909	LOC729020	rcRPE
chr14_+_100259445	0.396	NM_001008707 NM_004434	EML1	echinoderm microtubule associated protein like 1
chr18_+_32556891	0.395	NM_001143826	MAPRE2	microtubule-associated protein, RP/EB family, member 2
chrX_+_149613719	0.394	NM_001177466 NM_005491	MAMLD1	mastermind-like domain containing 1

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
3.06	1.37e-03	GO:0048856	anatomical structure development
468.48	1.59e-03	GO:0048014	Tie receptor signaling pathway
7.49	2.00e-03	GO:0042060	wound healing
4.42	3.69e-03	GO:0009653	anatomical structure morphogenesis
8.32	4.45e-03	GO:0072358	cardiovascular system development
8.32	4.45e-03	GO:0072359	circulatory system development
5.60	4.83e-03	GO:0009611	response to wounding
2.60	1.27e-02	GO:0032502	developmental process
2.97	1.33e-02	GO:0048731	system development
12.30	1.51e-02	GO:0048514	blood vessel morphogenesis
6.78	1.67e-02	GO:0050878	regulation of body fluid levels
2.69	1.94e-02	GO:0007275	multicellular organismal development
3.51	3.28e-02	GO:0048583	regulation of response to stimulus
10.13	3.81e-02	GO:0001568	blood vessel development
31.27	4.07e-02	GO:0010594	regulation of endothelial cell migration

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
5.63	2.10e-04	GO:0044421	extracellular region part
3.98	5.93e-04	GO:0005576	extracellular region
5.67	2.54e-03	GO:0005615	extracellular space

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
70.30	4.22e-04	GO:0030971	receptor tyrosine kinase binding
5.02	1.45e-03	GO:0005102	receptor binding
40.19	2.37e-03	GO:0005518	collagen binding