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Motif ID: SPIB.p2

Z-value: 1.959

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr12_-_15114495	7.815	NM_001175	ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta
chrX_+_48542159	4.573	NM_000377	WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
chr18_-_53068755	3.695		TCF4	transcription factor 4
chr2_-_175499275	3.128	NM_003387	WIPF1	WAS/WASL interacting protein family, member 1
chr17_+_34431219	2.884	NM_002984	CCL4	chemokine (C-C motif) ligand 4
chr12_+_25205180	2.811	NM_001204126 NM_001204127 NM_006152	LRMP	lymphoid-restricted membrane protein
chr12_+_25205488	2.769		LRMP	lymphoid-restricted membrane protein
chr17_+_34640030	2.695	NM_207007 NM_001001435	CCL4L2 CCL4L1	chemokine (C-C motif) ligand 4-like 2 chemokine (C-C motif) ligand 4-like 1
chr22_+_23222897	2.668		CYAT1	immunoglobulin lambda light chain-like
chr3_-_121379757	2.618	NM_005335	HCLS1	hematopoietic cell-specific Lyn substrate 1
chr19_+_49838673	2.462	NM_001040031 NM_001774	CD37	CD37 molecule
chr19_+_49838700	2.406		CD37	CD37 molecule
chr6_-_32160289	2.391		GPSM3	G-protein signaling modulator 3
chr17_+_67410825	2.389	NM_002758	MAP2K6	mitogen-activated protein kinase kinase 6
chr1_-_25256364	2.330		RUNX3	runt-related transcription factor 3
chr3_-_121379701	2.324		HCLS1	hematopoietic cell-specific Lyn substrate 1
chr19_+_49838646	2.320		CD37	CD37 molecule
chr10_+_70847857	2.295		SRGN	serglycin
chr1_-_183560010	2.284	NM_001127651	NCF2	neutrophil cytosolic factor 2
chr4_+_40198526	2.241	NM_004310	RHOH	ras homolog gene family, member H
chr2_-_96811138	2.223	NM_004418	DUSP2	dual specificity phosphatase 2
chr1_-_183559669	2.192	NM_000433 NM_001190789 NM_001190794	NCF2	neutrophil cytosolic factor 2
chr12_+_54891539	2.148		NCKAP1L	NCK-associated protein 1-like
chr10_+_70847817	2.139	NM_002727	SRGN	serglycin
chr16_+_30194925	2.089		CORO1A	coronin, actin binding protein, 1A
chr11_-_33890931	1.986		LMO2	LIM domain only 2 (rhombotin-like 1)
chr14_+_88471467	1.968	NM_003608	GPR65	G protein-coupled receptor 65
chr12_+_54891522	1.949		NCKAP1L	NCK-associated protein 1-like
chr19_-_36233311	1.933	NM_024660	IGFLR1	IGF-like family receptor 1
chr17_+_34538464	1.885	NM_207007 NM_001001435	CCL4L2 CCL4L1	chemokine (C-C motif) ligand 4-like 2 chemokine (C-C motif) ligand 4-like 1
chr12_+_54891491	1.883	NM_005337	NCKAP1L	NCK-associated protein 1-like
chr18_-_53177999	1.851	NM_001243231	TCF4	transcription factor 4
chr19_+_49838734	1.843		CD37	CD37 molecule
chrX_-_70331297	1.839	NM_000206	IL2RG	interleukin 2 receptor, gamma
chr12_+_7060517	1.836		PTPN6	protein tyrosine phosphatase, non-receptor type 6
chr12_+_7060538	1.820		PTPN6	protein tyrosine phosphatase, non-receptor type 6
chr1_-_183559463	1.813		NCF2	neutrophil cytosolic factor 2
chr12_+_7060543	1.803		PTPN6	protein tyrosine phosphatase, non-receptor type 6
chr5_-_169724734	1.794		LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr3_+_48507209	1.790	NM_016381 NM_033629	TREX1	three prime repair exonuclease 1
chr12_+_7060531	1.778		PTPN6	protein tyrosine phosphatase, non-receptor type 6
chr17_-_29641094	1.776	NM_006495	EVI2B	ecotropic viral integration site 2B
chr5_-_169724817	1.744	NM_005565	LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr5_-_169724782	1.736		LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr12_+_7060433	1.703	NM_002831 NM_080549	PTPN6	protein tyrosine phosphatase, non-receptor type 6
chr17_-_29641087	1.701		EVI2B	ecotropic viral integration site 2B
chrX_-_100641143	1.696	NM_000061	BTK	Bruton agammaglobulinemia tyrosine kinase
chr12_+_7060554	1.681		PTPN6	protein tyrosine phosphatase, non-receptor type 6
chrX_-_112066353	1.655	NM_001113490	AMOT	angiomotin
chr6_-_32634287	1.651	NM_001243961 NM_002123	HLA-DQB1	major histocompatibility complex, class II, DQ beta 1
chr11_-_33891361	1.643	NM_001142316	LMO2	LIM domain only 2 (rhombotin-like 1)
chr4_-_25864430	1.619	NM_015187	SEL1L3	sel-1 suppressor of lin-12-like 3 (C. elegans)
chrX_+_48542193	1.609		WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
chr11_-_33891258	1.580		LMO2	LIM domain only 2 (rhombotin-like 1)
chr5_+_169064274	1.566		DOCK2	dedicator of cytokinesis 2
chr17_-_29641068	1.557		EVI2B	ecotropic viral integration site 2B
chr1_-_207095198	1.557	NM_001193338 NM_001142473 NM_005449	FAIM3	Fas apoptotic inhibitory molecule 3
chr4_+_68424444	1.554	NM_012108	STAP1	signal transducing adaptor family member 1
chr3_-_119278402	1.545	NM_005191	CD80	CD80 molecule
chr12_+_4382882	1.544	NM_001759	CCND2	cyclin D2
chr17_-_29648631	1.495	NM_001003927 NM_014210	EVI2A	ecotropic viral integration site 2A
chr17_-_62084282	1.466	NM_000873	ICAM2	intercellular adhesion molecule 2
chr17_+_40439564	1.422	NM_003152	STAT5A	signal transducer and activator of transcription 5A
chr12_+_48499655	1.404	NM_001166686	PFKM	phosphofructokinase, muscle
chr4_+_103422822	1.392		NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chrX_-_135863104	1.384		ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr1_-_25291474	1.377	NM_001031680	RUNX3	runt-related transcription factor 3
chrX_-_135863033	1.370		ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr7_-_37488554	1.364	NM_014800	ELMO1	engulfment and cell motility 1
chr6_-_154677868	1.354	NM_001130700 NM_015553	IPCEF1	interaction protein for cytohesin exchange factors 1
chr11_+_102188180	1.353	NM_001165 NM_182962	BIRC3	baculoviral IAP repeat containing 3
chr7_-_37488408	1.302		ELMO1	engulfment and cell motility 1
chr7_-_37488894	1.297	NM_001206480	ELMO1	engulfment and cell motility 1
chr13_-_49110117	1.293		RCBTB2	regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr1_-_23886284	1.292	NM_002167	ID3	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr1_+_209929378	1.289	NM_025228	TRAF3IP3	TRAF3 interacting protein 3
chr18_-_60986508	1.273	NM_000633 NM_000657	BCL2	B-cell CLL/lymphoma 2
chr12_-_110434057	1.273		GIT2	G protein-coupled receptor kinase interacting ArfGAP 2
chr4_-_105412466	1.268	NM_025212	CXXC4	CXXC finger protein 4
chr18_-_53303129	1.267	NM_001243226	TCF4	transcription factor 4
chr14_+_100531764	1.253		EVL	Enah/Vasp-like
chr10_-_64576123	1.219	NM_000399 NM_001136177 NM_001136179	EGR2	early growth response 2
chr2_+_68592317	1.211	NM_002664	PLEK	pleckstrin
chr6_+_31582978	1.210	NM_004847 NM_001623	AIF1	allograft inflammatory factor 1
chr2_-_214015053	1.202	NM_016260	IKZF2	IKAROS family zinc finger 2 (Helios)
chr5_+_118691692	1.190		TNFAIP8	tumor necrosis factor, alpha-induced protein 8
chr6_+_31539875	1.182	NM_001159740	LTA	lymphotoxin alpha (TNF superfamily, member 1)
chr16_+_28943259	1.179	NM_001178098 NM_001770	CD19	CD19 molecule
chr11_-_67205151	1.146	NM_005608	PTPRCAP	protein tyrosine phosphatase, receptor type, C-associated protein
chr11_-_58343308	1.146	NM_004811	LPXN	leupaxin
chrX_-_15873094	1.142	NM_003916	AP1S2	adaptor-related protein complex 1, sigma 2 subunit
chr10_-_64576074	1.123		EGR2	early growth response 2
chr11_-_33891485	1.121	NM_001142315	LMO2	LIM domain only 2 (rhombotin-like 1)
chr19_-_6481765	1.110	NM_024898	DENND1C	DENN/MADD domain containing 1C
chr1_-_31230594	1.098		LAPTM5	lysosomal protein transmembrane 5
chr1_+_183774214	1.090		RGL1	ral guanine nucleotide dissociation stimulator-like 1
chr14_+_100531745	1.084	NM_016337	EVL	Enah/Vasp-like
chr17_+_76164624	1.082	NM_004710	SYNGR2	synaptogyrin 2
chr14_+_64971504	1.058		ZBTB1	zinc finger and BTB domain containing 1
chr7_+_150264457	1.056	NM_018326	GIMAP4	GTPase, IMAP family member 4
chr7_+_69063768	1.041	NM_001127231 NM_001127232 NM_015570	AUTS2	autism susceptibility candidate 2
chr13_-_46756326	1.037	NM_002298	LCP1	lymphocyte cytosolic protein 1 (L-plastin)
chr5_-_169724614	1.036		LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr1_-_25256767	1.035	NM_004350	RUNX3	runt-related transcription factor 3
chr21_-_39870303	1.034	NM_001136155 NM_182918	ERG	v-ets erythroblastosis virus E26 oncogene homolog (avian)
chr13_-_46756295	1.025		LCP1	lymphocyte cytosolic protein 1 (L-plastin)
chr8_-_95449131	1.018	NM_001205263	RAD54B	RAD54 homolog B (S. cerevisiae)
chr4_+_103422730	1.017		NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr8_-_6420454	1.013	NM_001118887 NM_001118888 NM_001147	ANGPT2	angiopoietin 2
chr15_+_81589240	1.008	NM_004513	IL16	interleukin 16
chr1_-_31230673	1.004	NM_006762	LAPTM5	lysosomal protein transmembrane 5
chr17_-_38721701	1.001	NM_001838	CCR7	chemokine (C-C motif) receptor 7
chr6_+_32407618	0.996	NM_019111	HLA-DRA	major histocompatibility complex, class II, DR alpha
chr17_+_25958192	0.995		LGALS9	lectin, galactoside-binding, soluble, 9
chr1_-_173174611	0.994		TNFSF4	tumor necrosis factor (ligand) superfamily, member 4
chr16_+_81812899	0.994		PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr17_+_25958151	0.982	NM_002308 NM_009587	LGALS9	lectin, galactoside-binding, soluble, 9
chr16_+_81812925	0.981		PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr19_-_39826676	0.975	NM_004877	GMFG	glia maturation factor, gamma
chr12_-_102874373	0.971	NM_000618 NM_001111283 NM_001111285	IGF1	insulin-like growth factor 1 (somatomedin C)
chr6_+_31543340	0.961	NM_000594	TNF	tumor necrosis factor
chr12_-_102874158	0.958		IGF1	insulin-like growth factor 1 (somatomedin C)
chr10_+_35484829	0.957	NM_182721 NM_182722 NM_182723 NM_182724 NM_182725	CREM	cAMP responsive element modulator
chr17_+_25958245	0.938		LGALS9	lectin, galactoside-binding, soluble, 9
chr17_+_25958217	0.934		LGALS9	lectin, galactoside-binding, soluble, 9
chr19_-_39826625	0.930		GMFG	glia maturation factor, gamma
chrX_+_12994286	0.925		TMSB4X	thymosin beta 4, X-linked
chr22_-_37545944	0.924	NM_000878	IL2RB	interleukin 2 receptor, beta
chrX_-_74376075	0.922	NM_004299	ABCB7	ATP-binding cassette, sub-family B (MDR/TAP), member 7
chr1_+_26644458	0.918		CD52	CD52 molecule
chr8_-_22550708	0.914	NM_004430	EGR3	early growth response 3
chr5_+_169064238	0.907	NM_004946	DOCK2	dedicator of cytokinesis 2
chr19_-_41859253	0.907		TGFB1	transforming growth factor, beta 1
chr16_+_30194730	0.896	NM_001193333 NM_007074	CORO1A	coronin, actin binding protein, 1A
chr17_+_18380097	0.896	NM_001040078	LGALS9B LGALS9C	lectin, galactoside-binding, soluble, 9B lectin, galactoside-binding, soluble, 9C
chr11_+_5646206	0.895	NM_021616	TRIM34	tripartite motif containing 34
chr1_-_160617042	0.895	NM_003037	SLAMF1	signaling lymphocytic activation molecule family member 1
chr22_+_22723972	0.892
chr20_+_44746889	0.891	NM_001250 NM_152854	CD40	CD40 molecule, TNF receptor superfamily member 5
chrX_+_37639246	0.885	NM_000397	CYBB	cytochrome b-245, beta polypeptide
chr8_-_22550057	0.879	NM_001199881	EGR3	early growth response 3
chr17_+_25958257	0.878		LGALS9	lectin, galactoside-binding, soluble, 9
chr1_-_23885916	0.878		ID3	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr1_+_26644380	0.871	NM_001803	CD52	CD52 molecule
chr7_+_128580725	0.870	NM_001098627	IRF5	interferon regulatory factor 5
chr22_+_23165273	0.870
chr9_+_71320105	0.849	NM_003558	PIP5K1B	phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr3_+_48507621	0.849		TREX1	three prime repair exonuclease 1
chr14_-_107131217	0.845		IGHA1	immunoglobulin heavy constant alpha 1
chrX_-_129244652	0.839	NM_001127197	ELF4	E74-like factor 4 (ets domain transcription factor)
chr16_+_81812897	0.837	NM_002661	PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr19_-_13213973	0.836	NM_005583	LYL1	lymphoblastic leukemia derived sequence 1
chr11_+_61560352	0.833		FEN1	flap structure-specific endonuclease 1
chr18_-_53089722	0.832	NM_001243233	TCF4	transcription factor 4
chr14_-_106967528	0.828		IGHA1 IGHA2 IGHG1 IGHM	immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant alpha 2 (A2m marker) immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant mu
chr17_-_40833840	0.826	NM_016602	CCR10	chemokine (C-C motif) receptor 10
chr1_-_111743297	0.820		DENND2D	DENN/MADD domain containing 2D
chr11_+_7618416	0.819		PPFIBP2	PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr2_-_60780404	0.818	NM_018014 NM_022893 NM_138559	BCL11A	B-cell CLL/lymphoma 11A (zinc finger protein)
chr16_+_30483959	0.803	NM_001114380 NM_002209	ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr22_-_37640287	0.800	NM_002872	RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr11_-_62472901	0.799
chr3_-_16555128	0.797	NM_015150	RFTN1	raftlin, lipid raft linker 1
chr15_-_43785266	0.791	NM_001141979 NM_001141980	TP53BP1	tumor protein p53 binding protein 1
chr3_-_16554992	0.789		RFTN1	raftlin, lipid raft linker 1
chr6_-_6320897	0.788	NM_000129	F13A1	coagulation factor XIII, A1 polypeptide
chr12_+_120105656	0.777	NM_006253	PRKAB1	protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr3_+_69134057	0.767	NM_006407	ARL6IP5	ADP-ribosylation-like factor 6 interacting protein 5
chr10_-_98031154	0.767	NM_001114094 NM_013314	BLNK	B-cell linker
chr1_+_150245182	0.766	NM_024579	C1orf54	chromosome 1 open reading frame 54
chr22_+_23213671	0.765		IGLV4-3	immunoglobulin lambda variable 4-3
chr3_+_152017193	0.764	NM_207293 NM_207294 NM_207295 NM_207296 NM_207297	MBNL1	muscleblind-like (Drosophila)
chr12_-_102874299	0.763		IGF1	insulin-like growth factor 1 (somatomedin C)
chr10_-_27149892	0.762		ABI1	abl-interactor 1
chr2_-_89165652	0.760
chr1_-_226926875	0.757	NM_002221	ITPKB	inositol-trisphosphate 3-kinase B
chr7_+_116660291	0.756		ST7	suppression of tumorigenicity 7
chrX_+_78200828	0.753	NM_014499 NM_198333	P2RY10	purinergic receptor P2Y, G-protein coupled, 10
chr3_+_16926451	0.751	NM_001144382	PLCL2	phospholipase C-like 2
chrX_+_119737743	0.750	NM_014060	MCTS1	malignant T cell amplified sequence 1
chr11_+_61560401	0.750		FEN1	flap structure-specific endonuclease 1
chr3_+_4535030	0.747	NM_001099952 NM_001168272 NM_002222	ITPR1	inositol 1,4,5-trisphosphate receptor, type 1
chr3_+_4535160	0.746		ITPR1	inositol 1,4,5-trisphosphate receptor, type 1
chr10_+_97515408	0.745	NM_001164178 NM_001164181 NM_001164179 NM_001164182 NM_001164183 NM_001776	ENTPD1	ectonucleoside triphosphate diphosphohydrolase 1
chr14_-_106573348	0.745		IGHV4-31 IGHA1 IGHA2 IGHG1 IGHG3 IGHM	immunoglobulin heavy variable 4-31 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant alpha 2 (A2m marker) immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 3 (G3m marker) immunoglobulin heavy constant mu
chr7_+_99971132	0.744		PILRA	paired immunoglobin-like type 2 receptor alpha
chr8_+_98703361	0.740		MTDH	metadherin
chrX_+_119737984	0.735		MCTS1	malignant T cell amplified sequence 1
chr22_-_37640187	0.732		RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr8_+_38585703	0.731	NM_001146216	TACC1	transforming, acidic coiled-coil containing protein 1
chr2_+_143886969	0.730		ARHGAP15	Rho GTPase activating protein 15
chrX_+_37639306	0.724		CYBB	cytochrome b-245, beta polypeptide
chr20_+_44746948	0.723		CD40	CD40 molecule, TNF receptor superfamily member 5
chr19_+_35645614	0.720	NM_014164	FXYD5	FXYD domain containing ion transport regulator 5
chr2_-_74405800	0.719	NM_018221	MOB1A	MOB kinase activator 1A
chr2_+_143886898	0.717	NM_018460	ARHGAP15	Rho GTPase activating protein 15
chr13_-_46756291	0.712		LCP1	lymphocyte cytosolic protein 1 (L-plastin)
chr14_+_50087400	0.707	NM_002408	MGAT2	mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr15_+_75074714	0.705		CSK	c-src tyrosine kinase
chr19_-_41859519	0.700		TGFB1	transforming growth factor, beta 1

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
4.52	2.37e-09	GO:0002376	immune system process
11.79	4.58e-09	GO:0030036	actin cytoskeleton organization
10.00	4.23e-08	GO:0030029	actin filament-based process
5.61	2.41e-07	GO:0002682	regulation of immune system process
3.40	2.97e-07	GO:0048583	regulation of response to stimulus
4.86	7.40e-06	GO:0006955	immune response
6.35	1.55e-05	GO:0002684	positive regulation of immune system process
6.27	1.83e-05	GO:0050776	regulation of immune response
6.19	2.15e-05	GO:0007010	cytoskeleton organization
17.85	6.61e-05	GO:0007015	actin filament organization
1.66	7.07e-05	GO:0050789	regulation of biological process
1.82	7.14e-05	GO:0050896	response to stimulus
4.21	3.98e-04	GO:0006952	defense response
13.49	4.62e-04	GO:0050851	antigen receptor-mediated signaling pathway
46.22	8.02e-04	GO:0043029	T cell homeostasis
12.39	8.25e-04	GO:0002429	immune response-activating cell surface receptor signaling pathway
12.02	1.01e-03	GO:0002768	immune response-regulating cell surface receptor signaling pathway
1.56	1.04e-03	GO:0065007	biological regulation
6.73	1.14e-03	GO:0050778	positive regulation of immune response
2.33	1.58e-03	GO:0048518	positive regulation of biological process
1.97	1.68e-03	GO:0051716	cellular response to stimulus
11.04	1.80e-03	GO:0042110	T cell activation
8.47	2.48e-03	GO:0002757	immune response-activating signal transduction
8.31	2.84e-03	GO:0002764	immune response-regulating signaling pathway
8.26	2.97e-03	GO:0050867	positive regulation of cell activation
1.61	3.54e-03	GO:0050794	regulation of cellular process
31.52	4.17e-03	GO:0001776	leukocyte homeostasis
31.52	4.17e-03	GO:0002260	lymphocyte homeostasis
8.68	8.88e-03	GO:0002697	regulation of immune effector process
3.66	1.14e-02	GO:0048584	positive regulation of response to stimulus
6.81	1.23e-02	GO:0002253	activation of immune response
2.02	1.26e-02	GO:0007165	signal transduction
4.53	1.48e-02	GO:0001775	cell activation
6.58	1.57e-02	GO:0045321	leukocyte activation
7.89	1.65e-02	GO:0051251	positive regulation of lymphocyte activation
6.29	2.19e-02	GO:0050865	regulation of cell activation
12.94	2.42e-02	GO:0050671	positive regulation of lymphocyte proliferation
7.36	2.57e-02	GO:0002696	positive regulation of leukocyte activation
12.75	2.60e-02	GO:0032946	positive regulation of mononuclear cell proliferation
2.22	2.70e-02	GO:0006950	response to stress
12.57	2.79e-02	GO:0070665	positive regulation of leukocyte proliferation
7.19	2.99e-02	GO:0046649	lymphocyte activation
5.94	3.28e-02	GO:0048534	hemopoietic or lymphoid organ development
1.88	3.67e-02	GO:0023052	signaling
11.72	3.91e-02	GO:0048872	homeostasis of number of cells
3.09	4.04e-02	GO:0042981	regulation of apoptosis
3.06	4.38e-02	GO:0043067	regulation of programmed cell death

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
27.09	7.81e-05	GO:0005884	actin filament
6.55	2.38e-02	GO:0031252	cell leading edge
3.19	2.38e-02	GO:0031982	vesicle
57.77	4.06e-02	GO:0001891	phagocytic cup
3.16	4.82e-02	GO:0031988	membrane-bounded vesicle

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
5.31	4.83e-04	GO:0030695	GTPase regulator activity
5.16	6.27e-04	GO:0060589	nucleoside-triphosphatase regulator activity
5.91	4.91e-03	GO:0005083	small GTPase regulator activity
1.43	2.01e-02	GO:0005515	protein binding