Motif ID: SREBF1,2.p2

Z-value: 1.524


Transcription factors associated with SREBF1,2.p2:

Gene SymbolEntrez IDGene Name
SREBF1 6720 sterol regulatory element binding transcription factor 1
SREBF2 6721 sterol regulatory element binding transcription factor 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
SREBF2chr22_+_422291070.629.8e-03Click!
SREBF1chr17_-_17740288,
chr17_-_17740309		-0.476.5e-02Click!


Activity profile for motif SREBF1,2.p2.

activity profile for motif SREBF1,2.p2


Sorted Z-values histogram for motif SREBF1,2.p2

Sorted Z-values for motif SREBF1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SREBF1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr20_+_44519965 4.688 CTSA
cathepsin A
chr20_+_44520021 4.512 CTSA
cathepsin A
chr17_+_78075299 3.655 NM_000152
NM_001079803
NM_001079804
 GAA


glucosidase, alpha; acid


chr17_-_46688362 3.515 NM_004502
 HOXB7
homeobox B7
chr20_+_44519924 3.493 CTSA
cathepsin A
chr20_+_44520203 3.404 CTSA
cathepsin A
chr1_+_11866240 3.343 CLCN6
chloride channel 6
chr1_+_183605207 3.332 NM_015149
 RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr1_-_161193375 3.218 NM_001643
 APOA2
apolipoprotein A-II
chr15_-_72668301 3.205 NM_000520
 HEXA
hexosaminidase A (alpha polypeptide)
chr17_+_78075390 3.070 GAA
glucosidase, alpha; acid
chr7_+_150065859 3.019 NM_001099695
NM_001099696
NM_013400
 REPIN1


replication initiator 1


chr6_+_160390128 2.922 NM_000876
 IGF2R
insulin-like growth factor 2 receptor
chr19_+_10765106 2.846 ILF3
interleukin enhancer binding factor 3, 90kDa
chr20_+_44519590 2.667 NM_000308
NM_001127695
NM_001167594
 CTSA


cathepsin A


chrY_+_15016698 2.663 NM_004660
 DDX3Y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr16_-_5083933 2.595 NM_016256
 NAGPA
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr22_+_35777087 2.538 HMOX1
heme oxygenase (decycling) 1
chr17_-_46688279 2.531 HOXB7
homeobox B7
chr17_+_79935493 2.519 ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 1 of 1 entries
Enrichment   P-value GO Accession GO Term
31.09 4.21e-03 GO:0007040 lysosome organization

Gene overrepresentation in compartment category:

Showing 1 to 10 of 10 entries
Enrichment   P-value GO Accession GO Term
11.28 1.56e-03 GO:0005765 lysosomal membrane
9.90 6.88e-04 GO:0005774 vacuolar membrane
9.51 8.99e-04 GO:0044437 vacuolar part
8.48 6.19e-06 GO:0000323 lytic vacuole
8.48 6.19e-06 GO:0005764 lysosome
7.78 3.78e-06 GO:0005773 vacuole
4.60 6.14e-03 GO:0005768 endosome
1.63 3.40e-03 GO:0044444 cytoplasmic part
1.40 3.18e-02 GO:0005737 cytoplasm
1.38 3.43e-02 GO:0043227 membrane-bounded organelle

Nothing significant found in function category.