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• Activity deltas table
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Motif ID: SRY.p2

Z-value: 1.068

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr9_+_75766794	4.855		ANXA1	annexin A1
chr9_+_75766777	3.293	NM_000700	ANXA1	annexin A1
chr2_-_56151273	3.257	NM_001039348 NM_001039349	EFEMP1	EGF containing fibulin-like extracellular matrix protein 1
chr7_+_134464417	2.866		CALD1	caldesmon 1
chrX_-_99891690	2.803	NM_003270	TSPAN6	tetraspanin 6
chr12_-_28124915	2.319	NM_002820 NM_198965	PTHLH	parathyroid hormone-like hormone
chr2_-_216259197	2.115		FN1	fibronectin 1
chr2_+_102508333	2.083		MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4
chr21_+_35190586	1.767		ITSN1	intersectin 1 (SH3 domain protein)
chr8_+_32504250	1.731	NM_013959	NRG1	neuregulin 1
chr20_+_19915716	1.693		RIN2	Ras and Rab interactor 2
chrX_+_107683015	1.641	NM_000495 NM_033380	COL4A5	collagen, type IV, alpha 5
chr6_-_134498973	1.616	NM_001143677	SGK1	serum/glucocorticoid regulated kinase 1
chr5_+_140739589	1.606	NM_018923 NM_032096	PCDHGB2	protocadherin gamma subfamily B, 2
chr10_-_105845619	1.564	NM_000494	COL17A1	collagen, type XVII, alpha 1
chr13_-_45048436	1.561	NM_001243798	TSC22D1	TSC22 domain family, member 1
chr3_-_149086884	1.558		TM4SF1	transmembrane 4 L six family member 1
chr2_+_102508377	1.545		MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4
chr8_-_82395401	1.524	NM_001442	FABP4	fatty acid binding protein 4, adipocyte
chr13_-_110802708	1.502		COL4A1	collagen, type IV, alpha 1
chr20_+_19870209	1.501	NM_018993	RIN2	Ras and Rab interactor 2
chr12_+_13349720	1.433		EMP1	epithelial membrane protein 1
chr2_-_190044330	1.418	NM_000393	COL5A2	collagen, type V, alpha 2
chr12_-_89746244	1.396	NM_001946 NM_022652	DUSP6	dual specificity phosphatase 6
chr12_-_8815266	1.390		MFAP5	microfibrillar associated protein 5
chr10_-_105845556	1.381		COL17A1	collagen, type XVII, alpha 1
chr9_-_14314036	1.380	NM_001190737 NM_005596	NFIB	nuclear factor I/B
chr4_+_169418167	1.356	NM_001166108 NM_016081	PALLD	palladin, cytoskeletal associated protein
chr5_+_34687663	1.353	NM_001145523	RAI14	retinoic acid induced 14
chr12_-_52886971	1.346	NM_005554	KRT6A	keratin 6A
chr18_+_3451589	1.313	NM_170695 NM_173210	TGIF1	TGFB-induced factor homeobox 1
chrX_-_10544852	1.306	NM_001193277	MID1	midline 1 (Opitz/BBB syndrome)
chr18_-_21852189	1.274	NM_018030	OSBPL1A	oxysterol binding protein-like 1A
chr4_-_101439071	1.248	NM_001159694 NM_016242	EMCN	endomucin
chrX_+_135251454	1.245	NM_001159704	FHL1	four and a half LIM domains 1
chr9_-_107690526	1.244	NM_005502	ABCA1	ATP-binding cassette, sub-family A (ABC1), member 1
chr18_+_72922725	1.220	NM_005786	TSHZ1	teashirt zinc finger homeobox 1
chr1_+_81771844	1.219		LPHN2	latrophilin 2
chr2_+_102314162	1.205	NM_001242560 NM_004834 NM_145686 NM_001242559 NM_145687	MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4
chr4_-_90759446	1.184	NM_001146055	SNCA	synuclein, alpha (non A4 component of amyloid precursor)
chr1_+_84609941	1.181	NM_182948	PRKACB	protein kinase, cAMP-dependent, catalytic, beta
chr5_+_71502700	1.164		MAP1B	microtubule-associated protein 1B
chr2_-_151344145	1.163	NM_005168	RND3	Rho family GTPase 3
chr12_-_6233684	1.155	NM_000552	VWF	von Willebrand factor
chr11_+_101983170	1.154	NM_001195045	YAP1	Yes-associated protein 1
chr1_-_153606567	1.150	NM_001024210	S100A13	S100 calcium binding protein A13
chr6_+_139456240	1.149	NM_016217	HECA	headcase homolog (Drosophila)
chr11_+_129979330	1.145		APLP2	amyloid beta (A4) precursor-like protein 2
chr6_+_151561508	1.136		AKAP12	A kinase (PRKA) anchor protein 12
chr22_-_36236330	1.116		RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2
chr10_-_126849010	1.115		CTBP2	C-terminal binding protein 2
chr1_+_151032683	1.110		MLLT11	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr1_-_85930610	1.109		DDAH1	dimethylarginine dimethylaminohydrolase 1
chr1_+_155099935	1.101		EFNA1	ephrin-A1
chr2_-_225266710	1.094	NM_001122779 NM_024785	FAM124B	family with sequence similarity 124B
chr22_-_36236421	1.091	NM_001031695 NM_001082576 NM_001082577 NM_014309	RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2
chr6_+_151561094	1.077	NM_005100	AKAP12	A kinase (PRKA) anchor protein 12
chr22_-_36236264	1.076		RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2
chr10_-_126849066	1.054	NM_001329	CTBP2	C-terminal binding protein 2
chr7_-_27205123	1.052		HOXA9	homeobox A9
chrX_+_135251795	1.045	NM_001167819	FHL1	four and a half LIM domains 1
chr11_-_102668892	1.044	NM_001145938 NM_002421	MMP1	matrix metallopeptidase 1 (interstitial collagenase)
chr5_+_36606667	1.035		SLC1A3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr1_+_151032866	1.032		MLLT11	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr5_+_36606456	1.030	NM_001166696 NM_004172	SLC1A3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr7_-_107643330	1.024	NM_002291	LAMB1	laminin, beta 1
chr10_-_91102430	1.023		LIPA	lipase A, lysosomal acid, cholesterol esterase
chr3_-_123339178	1.020		MYLK	myosin light chain kinase
chr6_-_47277354	1.014		TNFRSF21	tumor necrosis factor receptor superfamily, member 21
chr1_-_163113938	1.006		RGS5	regulator of G-protein signaling 5
chr6_-_134639195	0.994	NM_001143676	SGK1	serum/glucocorticoid regulated kinase 1
chr1_+_151032880	0.991		MLLT11	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr7_-_27205148	0.989	NM_152739	HOXA9	homeobox A9
chr1_+_43766565	0.962	NM_001253357 NM_005424	TIE1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr18_+_47088400	0.950	NM_006033	LIPG	lipase, endothelial
chr1_+_84630575	0.940	NM_001242860 NM_001242861	PRKACB	protein kinase, cAMP-dependent, catalytic, beta
chr5_+_34684611	0.917	NM_001145521 NM_001145525	RAI14	retinoic acid induced 14
chr11_+_129991582	0.910		APLP2	amyloid beta (A4) precursor-like protein 2
chr12_+_79439432	0.909	NM_001135806	SYT1	synaptotagmin I
chr21_+_39628869	0.906	NM_170736	KCNJ15	potassium inwardly-rectifying channel, subfamily J, member 15
chr11_-_102668822	0.899		MMP1	matrix metallopeptidase 1 (interstitial collagenase)
chr7_-_41742666	0.897	NM_002192	INHBA	inhibin, beta A
chr7_+_134464372	0.886		CALD1	caldesmon 1
chr14_+_94577078	0.876	NM_001130080 NM_005532	IFI27	interferon, alpha-inducible protein 27
chr16_+_55515468	0.871	NM_001127891	MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr18_+_3447607	0.854	NM_173207	TGIF1	TGFB-induced factor homeobox 1
chrX_+_102611379	0.845	NM_001006612 NM_001006613 NM_001006614 NM_016303	WBP5	WW domain binding protein 5
chr12_-_95611023	0.843	NM_018351	FGD6	FYVE, RhoGEF and PH domain containing 6
chr9_+_27109138	0.836	NM_000459	TEK	TEK tyrosine kinase, endothelial
chr10_+_124134206	0.833		PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr10_+_124134093	0.831	NM_001001974	PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr2_-_165424993	0.824		GRB14	growth factor receptor-bound protein 14
chr18_+_56530060	0.823	NM_018181	ZNF532	zinc finger protein 532
chr5_+_140743755	0.813	NM_018918 NM_032054	PCDHGA5	protocadherin gamma subfamily A, 5
chr3_-_69037498	0.804		C3orf64	chromosome 3 open reading frame 64
chr12_-_71031174	0.804	NM_001109754	PTPRB	protein tyrosine phosphatase, receptor type, B
chr12_+_78225068	0.800	NM_014903	NAV3	neuron navigator 3
chrX_+_15525430	0.789	NM_001721	BMX	BMX non-receptor tyrosine kinase
chr11_+_19372270	0.787	NM_001111018	NAV2	neuron navigator 2
chr12_-_52845862	0.780	NM_005555	KRT6B	keratin 6B
chr1_+_66458389	0.776	NM_001037340	PDE4B	phosphodiesterase 4B, cAMP-specific
chr5_-_39424930	0.772		DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr8_-_13134028	0.763		DLC1	deleted in liver cancer 1
chrX_-_38079980	0.761	NM_001170750 NM_001170751 NM_001170752 NM_006307	SRPX	sushi-repeat containing protein, X-linked
chr15_+_43885251	0.754	NM_020990	CKMT1B CKMT1A	creatine kinase, mitochondrial 1B creatine kinase, mitochondrial 1A
chr3_+_62305395	0.752	NM_020685	C3orf14	chromosome 3 open reading frame 14
chr3_-_99833348	0.748	NM_001042459 NM_182909	FILIP1L	filamin A interacting protein 1-like
chr2_-_192711923	0.744	NM_004657	SDPR	serum deprivation response
chr17_-_39743085	0.741	NM_000526	KRT14	keratin 14
chr6_-_105627857	0.723	NM_022361	POPDC3	popeye domain containing 3
chr12_-_8815479	0.719		MFAP5	microfibrillar associated protein 5
chr22_-_19512859	0.716	NM_001130861 NM_003277	CLDN5	claudin 5
chr9_-_74383301	0.713	NM_001135820 NM_013390	TMEM2	transmembrane protein 2
chr8_+_79428335	0.710	NM_006823 NM_181839	PKIA	protein kinase (cAMP-dependent, catalytic) inhibitor alpha
chr9_-_14086901	0.707		NFIB	nuclear factor I/B
chr12_-_10251520	0.704	NM_016511	CLEC1A	C-type lectin domain family 1, member A
chr9_-_16727887	0.694		BNC2	basonuclin 2
chr22_+_38599026	0.692	NM_001161573	MAFF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
chr2_-_55237255	0.683	NM_007008	RTN4	reticulon 4
chr9_+_116343169	0.672		RGS3	regulator of G-protein signaling 3
chr7_+_102553343	0.671	NM_001031692 NM_005824	LRRC17	leucine rich repeat containing 17
chr4_+_146403955	0.661	NM_001003688	SMAD1	SMAD family member 1
chr9_-_14398981	0.660	NM_001190738	NFIB	nuclear factor I/B
chrX_-_100914816	0.655	NM_014782 NM_177949	ARMCX2	armadillo repeat containing, X-linked 2
chr18_+_29027731	0.653	NM_001944	DSG3	desmoglein 3
chr2_+_234621637	0.649	NM_019078	UGT1A5	UDP glucuronosyltransferase 1 family, polypeptide A5
chr4_-_186732047	0.649	NM_001145672	SORBS2	sorbin and SH3 domain containing 2
chr4_+_86699846	0.646	NM_001042669	ARHGAP24	Rho GTPase activating protein 24
chr5_-_168271852	0.644
chr19_-_19049790	0.638	NM_001145724	HOMER3	homer homolog 3 (Drosophila)
chr20_+_11898536	0.633	NM_014962	BTBD3	BTB (POZ) domain containing 3
chr2_+_183582667	0.628		DNAJC10	DnaJ (Hsp40) homolog, subfamily C, member 10
chr4_-_159093523	0.628		FAM198B	family with sequence similarity 198, member B
chrX_+_114827818	0.621	NM_001136025 NM_001172335	PLS3	plastin 3
chr3_-_195310770	0.620		APOD	apolipoprotein D
chr11_-_72380107	0.618	NM_001146209	PDE2A	phosphodiesterase 2A, cGMP-stimulated
chr9_+_97521930	0.617	NM_001193329	C9orf3	chromosome 9 open reading frame 3
chr18_+_61254533	0.616	NM_012397	SERPINB13	serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr1_-_173020011	0.614	NM_005092	TNFSF18	tumor necrosis factor (ligand) superfamily, member 18
chr11_-_17191287	0.612	NM_002645	PIK3C2A	phosphoinositide-3-kinase, class 2, alpha polypeptide
chr1_+_84647342	0.604	NM_001242862	PRKACB	protein kinase, cAMP-dependent, catalytic, beta
chr10_-_123356158	0.598	NM_001144915	FGFR2	fibroblast growth factor receptor 2
chr2_-_55199894	0.594
chr13_+_111134933	0.594		COL4A2	collagen, type IV, alpha 2
chr5_+_73109342	0.593	NM_001244364	RGNEF	190 kDa guanine nucleotide exchange factor
chr1_-_95392501	0.586	NM_001839	CNN3	calponin 3, acidic
chr3_-_111314181	0.575	NM_024508	ZBED2	zinc finger, BED-type containing 2
chr13_-_99630243	0.574	NM_001130048 NM_001130050	DOCK9	dedicator of cytokinesis 9
chr9_+_116342939	0.573	NM_021106	RGS3	regulator of G-protein signaling 3
chr4_-_16900028	0.572		LDB2	LIM domain binding 2
chr11_-_89322778	0.571	NM_001143837	NOX4	NADPH oxidase 4
chr6_+_12290528	0.568	NM_001168319 NM_001955	EDN1	endothelin 1
chr5_+_125758818	0.564	NM_001146320 NM_001146321 NM_023927	GRAMD3	GRAM domain containing 3
chr1_+_84630014	0.563	NM_001242857 NM_001242858 NM_001242859	PRKACB	protein kinase, cAMP-dependent, catalytic, beta
chr2_-_113594325	0.559	NM_000576	IL1B	interleukin 1, beta
chr8_-_18666295	0.558	NM_206909	PSD3	pleckstrin and Sec7 domain containing 3
chr8_-_62602285	0.555	NM_001164750 NM_001164751 NM_001164752 NM_001164753 NM_020164 NM_032467 NM_032468	ASPH	aspartate beta-hydroxylase
chr14_+_85996512	0.555		FLRT2	fibronectin leucine rich transmembrane protein 2
chr1_+_20915440	0.552	NM_001785	CDA	cytidine deaminase
chr2_-_188312872	0.551	NM_005795	CALCRL	calcitonin receptor-like
chr20_+_9288446	0.533	NM_000933	PLCB4	phospholipase C, beta 4
chr11_+_113931228	0.529	NM_001018011	ZBTB16	zinc finger and BTB domain containing 16
chr6_+_158733691	0.527	NM_001007466 NM_020245	TULP4	tubby like protein 4
chr4_-_186732208	0.522	NM_001145671	SORBS2	sorbin and SH3 domain containing 2
chr8_-_17580024	0.515	NM_001166393	MTUS1	microtubule associated tumor suppressor 1
chr4_+_169552752	0.515	NM_001166109	PALLD	palladin, cytoskeletal associated protein
chrX_+_15518899	0.512	NM_203281	BMX	BMX non-receptor tyrosine kinase
chr2_+_102953716	0.510	NM_003856	IL1RL1	interleukin 1 receptor-like 1
chr6_-_46889620	0.509	NM_001098518	GPR116	G protein-coupled receptor 116
chr15_+_99191671	0.506		IGF1R	insulin-like growth factor 1 receptor
chr10_-_118680978	0.504		KIAA1598	KIAA1598
chr12_-_50616425	0.503	NM_001113547	LIMA1	LIM domain and actin binding 1
chr16_+_57673206	0.500	NM_001145774	GPR56	G protein-coupled receptor 56
chr1_+_155100304	0.500	NM_004428 NM_182685	EFNA1	ephrin-A1
chr14_-_69354900	0.498		ACTN1	actinin, alpha 1
chr12_+_13043955	0.498	NM_003979	GPRC5A	G protein-coupled receptor, family C, group 5, member A
chr1_+_84630374	0.498		PRKACB	protein kinase, cAMP-dependent, catalytic, beta
chr1_+_66797775	0.497	NM_001037339	PDE4B	phosphodiesterase 4B, cAMP-specific
chr13_-_45011059	0.497	NM_006022	TSC22D1	TSC22 domain family, member 1
chr7_+_134576150	0.495	NM_033139 NM_033140	CALD1	caldesmon 1
chr13_-_38172862	0.494	NM_001135934 NM_001135935 NM_001135936 NM_006475	POSTN	periostin, osteoblast specific factor
chr15_-_50411405	0.489	NM_024837	ATP8B4	ATPase, class I, type 8B, member 4
chr9_+_706744	0.488	NM_153186	KANK1	KN motif and ankyrin repeat domains 1
chr8_-_134309448	0.488	NM_001135242 NM_006096	NDRG1	N-myc downstream regulated 1
chr2_-_113542970	0.487	NM_000575	IL1A	interleukin 1, alpha
chr5_+_140771482	0.486	NM_014004 NM_032088	PCDHGA8	protocadherin gamma subfamily A, 8
chr12_+_56915587	0.485	NM_002898	RBMS2	RNA binding motif, single stranded interacting protein 2
chr2_-_219157207	0.484	NM_022152	TMBIM1	transmembrane BAX inhibitor motif containing 1
chr2_-_31352489	0.479	NM_001253827	GALNT14	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chrX_-_107682600	0.478	NM_001847	COL4A6	collagen, type IV, alpha 6
chr17_-_15554809	0.475		TRIM16	tripartite motif containing 16
chr11_+_123986103	0.474	NM_001130142 NM_014622 NM_198315	VWA5A	von Willebrand factor A domain containing 5A
chrX_+_100805415	0.470	NM_016608	ARMCX1	armadillo repeat containing, X-linked 1
chr1_-_152297678	0.469	NM_002016	FLG	filaggrin
chr4_+_90816002	0.468	NM_007351	MMRN1	multimerin 1
chr4_-_139163222	0.466	NM_014331	SLC7A11	solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr11_+_69467210	0.463		CCND1	cyclin D1
chr12_-_8815370	0.452	NM_003480	MFAP5	microfibrillar associated protein 5
chr12_-_10151689	0.450	NM_001099431 NM_016509	CLEC1B	C-type lectin domain family 1, member B
chr3_+_122044010	0.450	NM_005213	CSTA	cystatin A (stefin A)

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
218.09	9.79e-03	GO:0050701	interleukin-1 secretion
1.85	2.21e-02	GO:0032501	multicellular organismal process
19.40	2.39e-02	GO:0001816	cytokine production
145.40	2.93e-02	GO:0032612	interleukin-1 production

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
10.70	7.15e-08	GO:0005578	proteinaceous extracellular matrix
8.86	6.11e-07	GO:0031012	extracellular matrix
17.82	1.17e-06	GO:0044420	extracellular matrix part
3.93	2.98e-04	GO:0044421	extracellular region part
65.44	9.79e-04	GO:0043205	fibril
2.77	3.37e-03	GO:0005576	extracellular region
15.06	1.27e-02	GO:0005604	basement membrane
72.71	2.82e-02	GO:0005587	collagen type IV
62.32	3.94e-02	GO:0030935	sheet-forming collagen
19.84	4.13e-02	GO:0005581	collagen

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
19.26	5.25e-05	GO:0005201	extracellular matrix structural constituent
4.33	7.23e-03	GO:0005198	structural molecule activity