Motif ID: STAT1,3.p3

Z-value: 1.128


Transcription factors associated with STAT1,3.p3:

Gene SymbolEntrez IDGene Name
STAT1 6772 signal transducer and activator of transcription 1, 91kDa
STAT3 6774 signal transducer and activator of transcription 3 (acute-phase response factor)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
STAT3chr17_-_40540491-0.439.6e-02Click!
STAT1chr2_-_1918788820.351.9e-01Click!


Activity profile for motif STAT1,3.p3.

activity profile for motif STAT1,3.p3


Sorted Z-values histogram for motif STAT1,3.p3

Sorted Z-values for motif STAT1,3.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of STAT1,3.p3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_55515468 9.088 NM_001127891
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr11_+_114167168 5.916 NNMT
nicotinamide N-methyltransferase
chr11_+_114167197 5.790 NNMT
nicotinamide N-methyltransferase
chr10_-_90750955 4.919 NM_001141945
ACTA2
actin, alpha 2, smooth muscle, aorta
chr10_-_75415748 3.186 NM_001114133
SYNPO2L
synaptopodin 2-like
chr1_-_203155827 2.549 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr1_-_203155910 2.198 NM_001276
CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr1_-_203155813 2.055 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr1_-_203155867 1.717 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr2_+_170366211 1.444 NM_006063
KBTBD10
kelch repeat and BTB (POZ) domain containing 10
chr6_+_36646455 1.325 NM_000389
NM_001220778
CDKN1A

cyclin-dependent kinase inhibitor 1A (p21, Cip1)

chr10_+_90751044 1.245 FAS
Fas (TNF receptor superfamily, member 6)
chr1_-_144994943 1.155 NM_001002812
NM_014644
NM_001002810
NM_001198834
NM_001195261
PDE4DIP




phosphodiesterase 4D interacting protein




chr11_+_32112414 1.034 NM_002901
RCN1
reticulocalbin 1, EF-hand calcium binding domain
chr4_-_129209983 0.844 NM_006320
PGRMC2
progesterone receptor membrane component 2
chr6_+_36646489 0.832 CDKN1A
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chr1_+_156084579 0.825 LMNA
lamin A/C
chr1_-_144994908 0.813 PDE4DIP
phosphodiesterase 4D interacting protein
chr9_+_132897342 0.707 GPR107
G protein-coupled receptor 107
chr3_-_15900928 0.678 NM_015199
ANKRD28
ankyrin repeat domain 28
chr6_-_31698033 0.634 NM_013974
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr11_+_32112607 0.631 RCN1
reticulocalbin 1, EF-hand calcium binding domain
chr1_-_203155745 0.605 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr15_+_33010174 0.560 NM_001191322
NM_001191323
NM_013372
GREM1


gremlin 1


chr5_+_134209426 0.554 NM_024715
TXNDC15
thioredoxin domain containing 15
chr1_-_144994839 0.552 PDE4DIP
phosphodiesterase 4D interacting protein
chr14_+_67707825 0.533 NM_022474
MPP5
membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
chr10_+_91152321 0.532 NM_001548
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr9_-_75567915 0.520 ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr7_+_80275634 0.516 NM_001127443
NM_001127444
CD36

CD36 molecule (thrombospondin receptor)

chr12_+_102271082 0.506 NM_018370
DRAM1
DNA-damage regulated autophagy modulator 1
chr19_+_35168558 0.483 NM_001012320
NM_018443
ZNF302

zinc finger protein 302

chr14_-_68141328 0.467 NM_006370
VTI1B
vesicle transport through interaction with t-SNAREs homolog 1B (yeast)
chr15_+_90808833 0.448 NM_001033088
NGRN
neugrin, neurite outgrowth associated
chr8_-_18666295 0.428 NM_206909
PSD3
pleckstrin and Sec7 domain containing 3
chr8_-_57906143 0.420 IMPAD1
inositol monophosphatase domain containing 1
chr11_-_47470687 0.404 NM_005055
NM_032645
RAPSN

receptor-associated protein of the synapse

chr14_-_92414004 0.381 NM_006329
FBLN5
fibulin 5
chr4_+_126237566 0.375 NM_024582
FAT4
FAT tumor suppressor homolog 4 (Drosophila)
chr8_-_57906402 0.357 IMPAD1
inositol monophosphatase domain containing 1
chr7_-_151511925 0.355 NM_001040633
PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr5_-_138725544 0.351 NM_016459
MZB1
marginal zone B and B1 cell-specific protein
chr3_+_23987514 0.344 NM_001145425
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr5_-_133706717 0.340 CDKL3
cyclin-dependent kinase-like 3
chr4_-_111563278 0.337 NM_001204397
NM_001204398
NM_001204399
NM_153426
NM_153427
PITX2




paired-like homeodomain 2




chr10_+_93558182 0.333 TNKS2
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
chr16_-_24968856 0.323 ARHGAP17
Rho GTPase activating protein 17
chr1_+_196621007 0.319 NM_000186
NM_001014975
CFH

complement factor H

chr1_-_54518886 0.319 TMEM59
transmembrane protein 59
chr12_-_123756164 0.317 NM_004642
CDK2AP1
cyclin-dependent kinase 2 associated protein 1
chr3_+_132316080 0.312 NM_016557
CCRL1
chemokine (C-C motif) receptor-like 1
chr6_-_27440459 0.302 NM_007149
ZNF184
zinc finger protein 184
chr3_-_81810618 0.301 GBE1
glucan (1,4-alpha-), branching enzyme 1
chr19_+_58144510 0.300 NM_006385
NM_198855
ZNF211

zinc finger protein 211

chrX_+_48432740 0.295 NM_006743
RBM3
RNA binding motif (RNP1, RRM) protein 3
chr11_+_7618416 0.294 PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr4_+_41540320 0.290 LIMCH1
LIM and calponin homology domains 1
chr8_-_57906423 0.284 NM_017813
IMPAD1
inositol monophosphatase domain containing 1
chr11_-_615920 0.283 IRF7
interferon regulatory factor 7
chr1_-_54518790 0.275 TMEM59
transmembrane protein 59
chr3_-_81810914 0.268 NM_000158
GBE1
glucan (1,4-alpha-), branching enzyme 1
chr6_-_132722564 0.265 NM_015529
MOXD1
monooxygenase, DBH-like 1
chr5_+_149887673 0.244 NM_001543
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr17_+_76183397 0.241 NM_001010982
NM_001145526
AFMID

arylformamidase

chr19_+_44529493 0.241 NM_001129996
NM_013360
ZNF284
ZNF222

zinc finger protein 284
zinc finger protein 222

chr1_-_54518915 0.240 TMEM59
transmembrane protein 59
chr12_-_69357019 0.231 NM_001874
CPM
carboxypeptidase M
chr20_-_43280359 0.230 NM_000022
ADA
adenosine deaminase
chr1_-_163113938 0.227 RGS5
regulator of G-protein signaling 5
chr5_+_133707105 0.225 UBE2B
ubiquitin-conjugating enzyme E2B
chr21_-_27543445 0.224 NM_001136131
APP
amyloid beta (A4) precursor protein
chr10_+_95848811 0.218 NM_001165979
PLCE1
phospholipase C, epsilon 1
chr8_-_57906376 0.211 IMPAD1
inositol monophosphatase domain containing 1
chr11_+_844111 0.205 TSPAN4
tetraspanin 4
chr10_+_86004808 0.201 NM_001012720
NM_001012722
NM_002921
RGR


retinal G protein coupled receptor


chr1_-_42630386 0.198 NM_033553
GUCA2A
guanylate cyclase activator 2A (guanylin)
chr19_+_44556163 0.188 NM_013361
ZNF223
zinc finger protein 223
chr3_-_81810816 0.185 GBE1
glucan (1,4-alpha-), branching enzyme 1
chr17_+_5972425 0.184 WSCD1
WSC domain containing 1
chr6_+_36644236 0.181 NM_001220777
NM_078467
CDKN1A

cyclin-dependent kinase inhibitor 1A (p21, Cip1)

chr8_+_1772095 0.179 NM_014629
ARHGEF10
Rho guanine nucleotide exchange factor (GEF) 10
chr1_-_155959860 0.176 ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr1_-_154946830 0.175 SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr19_+_44507076 0.174 NM_006300
ZNF230
zinc finger protein 230
chr3_+_135741576 0.172 NM_181897
PPP2R3A
protein phosphatase 2, regulatory subunit B'', alpha
chr9_-_23821477 0.170 NM_001171197
ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr14_+_24836144 0.153 NM_001136022
NM_001198967
NFATC4

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4

chr1_-_159046555 0.153 NM_004833
AIM2
absent in melanoma 2
chr1_-_160617042 0.152 NM_003037
SLAMF1
signaling lymphocytic activation molecule family member 1
chr22_+_18121540 0.151 BCL2L13
BCL2-like 13 (apoptosis facilitator)
chr12_+_3068989 0.148 TEAD4
TEA domain family member 4
chr11_-_615998 0.147 NM_001572
NM_004029
IRF7

interferon regulatory factor 7

chr1_+_149871154 0.145 NM_016074
BOLA1
bolA homolog 1 (E. coli)
chr1_-_154946859 0.144 NM_001130041
NM_001202859
NM_003029
SHC1


SHC (Src homology 2 domain containing) transforming protein 1


chr2_-_264037 0.143 NM_001159597
NM_015677
SH3YL1

SH3 domain containing, Ysc84-like 1 (S. cerevisiae)

chr11_-_615649 0.140 NM_004031
IRF7
interferon regulatory factor 7
chr15_-_43802666 0.136 NM_005657
TP53BP1
tumor protein p53 binding protein 1
chr3_+_48481706 0.132 CCDC72
coiled-coil domain containing 72
chr12_-_54070108 0.131 NM_005176
ATP5G2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr11_-_64490654 0.130 NM_015080
NM_138732
NRXN2

neurexin 2

chr14_+_55168831 0.128 SAMD4A
sterile alpha motif domain containing 4A
chr17_+_42422490 0.128 NM_002087
GRN
granulin
chrX_-_134185978 0.127 NM_001078172
NM_001134321
FAM127B

family with sequence similarity 127, member B

chr22_-_24096551 0.120 NM_013378
VPREB3
pre-B lymphocyte 3
chr2_-_86094792 0.118 NM_001042437
ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chrX_-_100548044 0.117 NM_024885
TAF7L
TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa
chr1_+_111770280 0.114 NM_001025197
NM_004000
CHI3L2

chitinase 3-like 2

chr10_+_93558068 0.110 TNKS2
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
chr6_-_35480635 0.108 NM_003322
TULP1
tubby like protein 1
chr7_-_108096693 0.107 NM_001193582
NM_001193583
NM_001193584
NM_005010
NRCAM



neuronal cell adhesion molecule



chr5_+_109025135 0.106 NM_002372
MAN2A1
mannosidase, alpha, class 2A, member 1
chr10_+_71029755 0.101 NM_033497
NM_033498
NM_033500
HK1


hexokinase 1


chr11_-_102668822 0.101 MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr5_-_139943829 0.099 APBB3
amyloid beta (A4) precursor protein-binding, family B, member 3
chr7_-_72972021 0.096 NM_001197244
NM_001707
BCL7B

B-cell CLL/lymphoma 7B

chr2_+_17935379 0.095 NM_001130009
GEN1
Gen endonuclease homolog 1 (Drosophila)
chr22_+_18121446 0.087 NM_015367
BCL2L13
BCL2-like 13 (apoptosis facilitator)
chr16_+_4674829 0.086 MGRN1
mahogunin, ring finger 1
chr15_-_73076057 0.085 ADPGK
ADP-dependent glucokinase
chr20_-_48184652 0.082 NM_000961
PTGIS
prostaglandin I2 (prostacyclin) synthase
chr3_-_129118241 0.081 RPL32P3
ribosomal protein L32 pseudogene 3
chr19_+_44455379 0.080 NM_013359
ZNF221
zinc finger protein 221
chr13_-_95953572 0.080 NM_001105515
NM_005845
ABCC4

ATP-binding cassette, sub-family C (CFTR/MRP), member 4

chr7_-_100171269 0.073 NM_001168682
SAP25
Sin3A-associated protein, 25kDa
chr1_-_54519050 0.071 NM_004872
TMEM59
transmembrane protein 59
chr6_+_31540092 0.069 NM_000595
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr6_+_97010423 0.068 NM_001170807
NM_020482
FHL5

four and a half LIM domains 5

chr1_-_25558957 0.067 NM_015484
NM_207170
SYF2

SYF2 homolog, RNA splicing factor (S. cerevisiae)

chr10_+_93558139 0.067 NM_025235
TNKS2
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
chr11_-_102668892 0.066 NM_001145938
NM_002421
MMP1

matrix metallopeptidase 1 (interstitial collagenase)

chr19_+_44617510 0.062 NM_013362
ZNF225
zinc finger protein 225
chr5_-_139944045 0.061 NM_006051
NM_133172
NM_133173
NM_133174
APBB3



amyloid beta (A4) precursor protein-binding, family B, member 3



chr19_-_45004482 0.061 NM_013256
ZNF180
zinc finger protein 180
chr3_+_187871473 0.060 NM_001167672
LPP
LIM domain containing preferred translocation partner in lipoma
chr3_-_169587598 0.060 NM_024727
LRRC31
leucine rich repeat containing 31
chr9_-_131038196 0.058 NM_004486
GOLGA2
golgin A2
chr15_-_64385988 0.055 NM_001014812
NM_032231
FAM96A

family with sequence similarity 96, member A

chr17_-_3030844 0.053 NM_003555
OR1G1
olfactory receptor, family 1, subfamily G, member 1
chr9_-_134585107 0.053 NM_198679
RAPGEF1
Rap guanine nucleotide exchange factor (GEF) 1
chr15_-_73076071 0.052 ADPGK
ADP-dependent glucokinase
chr8_+_11351509 0.047 NM_001715
BLK
B lymphoid tyrosine kinase
chr11_-_118966175 0.046 NM_002105
H2AFX
H2A histone family, member X
chrX_-_107334749 0.045 NM_002814
NM_170750
PSMD10

proteasome (prosome, macropain) 26S subunit, non-ATPase, 10

chr2_-_68384575 0.044 NM_138458
WDR92
WD repeat domain 92
chr11_-_118966103 0.043 H2AFX
H2A histone family, member X
chr11_+_61447816 0.043 NM_006133
DAGLA
diacylglycerol lipase, alpha
chr19_+_44488331 0.038 NM_003445
NM_198089
ZNF155

zinc finger protein 155

chr19_-_3984152 0.037 EEF2
eukaryotic translation elongation factor 2
chr1_+_113010039 0.037 NM_004185
WNT2B
wingless-type MMTV integration site family, member 2B
chr19_-_44809126 0.037 NM_004234
ZNF235
zinc finger protein 235
chr14_-_93214873 0.036 NM_001008530
NM_005606
LGMN

legumain

chr19_+_10828813 0.034 DNM2
dynamin 2
chr1_-_207119707 0.034 NM_002644
PIGR
polymeric immunoglobulin receptor
chr3_+_187086167 0.033 NM_022147
RTP4
receptor (chemosensory) transporter protein 4
chr6_-_28303910 0.031 NM_001135216
NM_001243243
ZNF323

zinc finger protein 323

chr12_+_104324186 0.030 NM_003299
HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr22_+_36044412 0.030 NM_030641
APOL6
apolipoprotein L, 6
chr5_+_179132676 0.029 CANX
calnexin
chr11_+_61197574 0.029 NM_017841
SDHAF2
succinate dehydrogenase complex assembly factor 2
chr19_+_10828763 0.028 DNM2
dynamin 2
chr19_-_36980336 0.028 NM_032838
NM_001145343
NM_001145344
NM_001145345
ZNF566



zinc finger protein 566



chr8_+_27183062 0.028 NM_173175
PTK2B
PTK2B protein tyrosine kinase 2 beta
chr22_-_50699687 0.027 MAPK12
mitogen-activated protein kinase 12
chr4_+_148402244 0.027 EDNRA
endothelin receptor type A
chr3_-_118959723 0.026 NM_003778
NM_212543
B4GALT4

UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4

chr4_-_87813546 0.025 NM_144645
C4orf36
chromosome 4 open reading frame 36
chr19_-_38720312 0.025 NM_001135156
DPF1
D4, zinc and double PHD fingers family 1
chr9_+_136287443 0.025 ADAMTS13
ADAM metallopeptidase with thrombospondin type 1 motif, 13
chr12_-_7261788 0.025 NM_016546
C1RL
complement component 1, r subcomponent-like
chr17_+_71229357 0.025 C17orf80
chromosome 17 open reading frame 80
chr19_-_4831711 0.024 NM_182919
TICAM1
toll-like receptor adaptor molecule 1
chr5_-_179498995 0.023 NM_018434
RNF130
ring finger protein 130
chr12_-_56727720 0.022 NM_001166279
NM_014871
PAN2

PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)

chr12_+_104324214 0.022 HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr12_+_104324192 0.022 HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr19_+_44716683 0.021 NM_182490
ZNF227
zinc finger protein 227
chr12_+_3068442 0.020 NM_003213
NM_201441
NM_201443
TEAD4


TEA domain family member 4


chr3_+_37284680 0.020 NM_001172713
NM_002078
GOLGA4

golgin A4

chr19_+_48867650 0.019 NM_012451
SYNGR4
synaptogyrin 4
chr6_+_42531767 0.018 UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr19_+_10828725 0.016 NM_001005360
NM_001005361
NM_001005362
NM_001190716
NM_004945
DNM2




dynamin 2




chr12_+_104324157 0.016 HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr13_-_99738639 0.016 NM_001130049
NM_015296
DOCK9

dedicator of cytokinesis 9

chr2_+_131862885 0.015 PLEKHB2
pleckstrin homology domain containing, family B (evectins) member 2
chr17_-_48546174 0.015 NM_001267
CHAD
chondroadherin
chr12_+_22778085 0.014 ETNK1
ethanolamine kinase 1
chr5_+_161274196 0.012 NM_000806
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr1_+_36690038 0.011 THRAP3
thyroid hormone receptor associated protein 3
chr5_-_140012730 0.011 CD14
CD14 molecule
chrY_+_535078 0.011 NM_000451
NM_006883
SHOX

short stature homeobox

chrX_+_585078 0.010 NM_000451
NM_006883
SHOX

short stature homeobox

chr12_-_10962673 0.009 NM_023917
TAS2R9
taste receptor, type 2, member 9
chr5_+_175875386 0.009 FAF2
Fas associated factor family member 2
chr13_+_25946084 0.008 NM_016529
ATP8A2
ATPase, aminophospholipid transporter, class I, type 8A, member 2
chr7_+_150549577 0.008 ABP1
amiloride binding protein 1 (amine oxidase (copper-containing))
chr3_+_46283871 0.007 NM_001164680
NM_001837
NM_178328
NM_178329
CCR3



chemokine (C-C motif) receptor 3



chr17_+_32683470 0.005 NM_005408
CCL13
chemokine (C-C motif) ligand 13
chr5_+_73109342 0.005 NM_001244364
RGNEF
190 kDa guanine nucleotide exchange factor
chr4_-_185395616 0.004 NM_002199
IRF2
interferon regulatory factor 2
chr5_-_140013285 0.004 NM_001040021
NM_001174104
NM_001174105
CD14


CD14 molecule



Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.