Motif ID: TBX4,5.p2
Z-value: 2.097
Transcription factors associated with TBX4,5.p2:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| TBX4 | 9496 | T-box 4 |
| TBX5 | 6910 | T-box 5 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| TBX5 | chr12_-_114841702 | 0.22 | 4.2e-01 | Click! |
| TBX4 | chr17_+_59533806 | -0.21 | 4.3e-01 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in process category:
Showing 1 to 16 of 16 entries
| Enrichment | P-value | GO Accession | GO Term |
|---|---|---|---|
| 46.86 | 2.17e-02 | GO:0051023 | regulation of immunoglobulin secretion |
| 38.34 | 4.22e-02 | GO:0050710 | negative regulation of cytokine secretion |
| 24.45 | 1.44e-02 | GO:0002637 | regulation of immunoglobulin production |
| 20.09 | 3.32e-03 | GO:0050707 | regulation of cytokine secretion |
| 18.75 | 4.30e-02 | GO:0006958 | complement activation, classical pathway |
| 15.98 | 1.06e-02 | GO:0002700 | regulation of production of molecular mediator of immune response |
| 14.96 | 1.47e-02 | GO:0050714 | positive regulation of protein secretion |
| 13.19 | 4.32e-03 | GO:0050708 | regulation of protein secretion |
| 11.72 | 4.87e-02 | GO:0072376 | protein activation cascade |
| 9.93 | 2.24e-02 | GO:0051222 | positive regulation of protein transport |
| 5.75 | 6.35e-03 | GO:0006954 | inflammatory response |
| 3.80 | 4.84e-02 | GO:0080134 | regulation of response to stress |
| 3.53 | 7.52e-04 | GO:0009611 | response to wounding |
| 3.51 | 6.87e-03 | GO:0006955 | immune response |
| 2.86 | 2.73e-05 | GO:0048583 | regulation of response to stimulus |
| 1.66 | 1.61e-03 | GO:0050896 | response to stimulus |
Gene overrepresentation in compartment category:
Showing 1 to 3 of 3 entries
| Enrichment | P-value | GO Accession | GO Term |
|---|---|---|---|
| 4.66 | 6.71e-08 | GO:0005615 | extracellular space |
| 3.70 | 4.58e-06 | GO:0044421 | extracellular region part |
| 3.07 | 3.27e-07 | GO:0005576 | extracellular region |
Gene overrepresentation in function category:
Showing 1 to 9 of 9 entries
| Enrichment | P-value | GO Accession | GO Term |
|---|---|---|---|
| 12.79 | 3.07e-02 | GO:0008009 | chemokine activity |
| 11.48 | 4.66e-02 | GO:0042379 | chemokine receptor binding |
| 11.20 | 1.10e-05 | GO:0004866 | endopeptidase inhibitor activity |
| 11.01 | 1.28e-05 | GO:0030414 | peptidase inhibitor activity |
| 10.73 | 1.60e-05 | GO:0061135 | endopeptidase regulator activity |
| 8.86 | 8.29e-05 | GO:0061134 | peptidase regulator activity |
| 6.97 | 4.97e-05 | GO:0004857 | enzyme inhibitor activity |
| 6.74 | 2.68e-03 | GO:0005125 | cytokine activity |
| 3.47 | 3.13e-04 | GO:0030234 | enzyme regulator activity |